Carboxylesterases of insects have been subdivided in clades A to M (Claudianos 2006 Ranson 2002). With the Dietary class (clades ABC), the Pheromone/hormone processing class (clades D to G), the Neuro/developmental class (H to M). The present family Carb_B_Arthropoda corresponds to clades ABC. Members of these clades are important in detoxifixtion of insecticides .Gene amplifications or point mutations leading to resistance. Clades D to M have their own family (AChE, JHE, Glutactin Neuroligin, Neurotactin). This family was extracted from the previous Carboxylesterase COesterase family. This family corresponds to the Carbohydrate Esterase family CE10 in CAZy - Carbohydrate-Active enZYmes database (CE_10).
Interpro : IPR002018 Carboxylesterase, type B
PIRSF : PIRSF005676 COesterase
Pdoc : PDOC00112
Pfam : PF00135 COesterase
Prints : No Print
EC Number : 3.1.1.1
Structures (32)
Genes Proteins in Carb_B_Arthropoda family (1573)
Fragments of genes in Carb_B_Arthropoda family (763)
Structures in Carb_B_Arthropoda family (32)Substrates in Carb_B_Arthropoda family (32)
Inhibitors in Carb_B_Arthropoda family (12)
Title : Characteristics of carboxylesterase genes and their expression-level between acaricide-susceptible and resistant Tetranychus cinnabarinus (Boisduval) - Wei_2016_Pestic.Biochem.Physiol_131_87 |
Author(s) : Wei P , Shi L , Shen G , Xu Z , Liu J , Pan Y , He L |
Ref : Pestic Biochem Physiol , 131 :87 , 2016 |
PubMedID: 27265830 |
Gene_locus related to this paper: tetur-t1jth5 , tetur-t1kth5 , tetur-t1kwe1 , tetur-t1kx09 , tetur-t1kxr8 , tetur-t1l430 , tetur-t1kgp1 , tetur-t1l0m8 , tetur-t1knw0 , tetur-t1kgp7 , tetur-t1l013 , tetur-t1jz51 , tetur-t1kg31 , tetur-t1knv9 , tetur-t1jrz3 , tetur-t1k786 , tetur-t1jth6 , tetur-t1jtg9 , tetur-t1kpg7 , tetur-t1jvb8 , tetur-t1kvj7 |
Title : Mapping the Accessible Conformational Landscape of an Insect Carboxylesterase Using Conformational Ensemble Analysis and Kinetic Crystallography - Correy_2016_Structure_24_977 |
Author(s) : Correy GJ , Carr PD , Meirelles T , Mabbitt PD , Fraser NJ , Weik M , Jackson CJ |
Ref : Structure , 24 :977 , 2016 |
PubMedID: 27210287 |
Gene_locus related to this paper: luccu-E3aest7 |
Title : Functional characterization of an alpha-esterase gene involving malathion detoxification in Bactrocera dorsalis (Hendel) - Wang_2016_Pestic.Biochem.Physiol_130_44 |
Author(s) : Wang LL , Lu XP , Meng LW , Huang Y , Wei D , Jiang HB , Smagghe G , Wang JJ |
Ref : Pestic Biochem Physiol , 130 :44 , 2016 |
PubMedID: 27155483 |
Gene_locus related to this paper: bacdo-a0a034w7m1 |
Title : Structure and function of an insect alpha-carboxylesterase (alphaEsterase7) associated with insecticide resistance - Jackson_2013_Proc.Natl.Acad.Sci.U.S.A_110_10177 |
Author(s) : Jackson CJ , Liu JW , Carr PD , Younus F , Coppin C , Meirelles T , Lethier M , Pandey G , Ollis DL , Russell RJ , Weik M , Oakeshott JG |
Ref : Proc Natl Acad Sci U S A , 110 :10177 , 2013 |
PubMedID: 23733941 |
Gene_locus related to this paper: luccu-E3aest7 |
Title : A deficit of detoxification enzymes: pesticide sensitivity and environmental response in the honeybee - Claudianos_2006_Insect.Mol.Biol_15_615 |
Author(s) : Claudianos C , Ranson H , Johnson RM , Biswas S , Schuler MA , Berenbaum MR , Feyereisen R , Oakeshott JG |
Ref : Insect Molecular Biology , 15 :615 , 2006 |
PubMedID: 17069637 |
Gene_locus related to this paper: apime-b9vmq4 , apime-b9vmq5 , apime-b9vmq6 , apime-b9vmq7 , apime-a0a088atg1 |
Title : Quantitative polymerase chain reaction to estimate the number of amplified esterase genes in insecticide-resistant mosquitoes - |
Author(s) : Weill M , Berticat C , Raymond M , Chevillon C |
Ref : Analytical Biochemistry , 285 :267 , 2000 |
PubMedID: 11017713 |
Title : Carboxyl\/cholinesterases: a case study of the evolution of a successful multigene family - Oakeshott_1999_Bioessays_21_1031 |
Author(s) : Oakeshott JG , Claudianos C , Russell RJ , Robin GC |
Ref : Bioessays , 21 :1031 , 1999 |
PubMedID: 10580988 |
Title : A new esterase gene amplification involved in OP resistance in Culex pipiens mosquitoes from China - Qiao_1998_Biochem.Genet_36_417 |
Author(s) : Qiao CL , Marquine M , Pasteur N , Raymond M |
Ref : Biochemical Genetics , 36 :417 , 1998 |
PubMedID: 10230522 |
Title : A single amino acid substitution converts a carboxylesterase to an organophosphorus hydrolase and confers insecticide resistance on a blowfly - Newcomb_1997_Proc.Natl.Acad.Sci.U.S.A_94_7464 |
Author(s) : Newcomb RD , Campbell PM , Ollis DL , Cheah E , Russell RJ , Oakeshott JG |
Ref : Proceedings of the National Academy of Sciences of the United States of America , 94 :7464 , 1997 |
PubMedID: 9207114 |
Gene_locus related to this paper: luccu-ACHE , luccu-E3aest7 |
Title : Action of Esterase B1 on Chlorpyrifos in Organophosphate-Resistant Culex Mosquitos - Cuany_1993_Pestic.Biochem.Physiol_45_1 |
Author(s) : Cuany A , Handani J , Berge J , Fournier D , Raymond M , Georghiou GP , Pasteur N |
Ref : Pesticide Biochemistry and Physiology , 45 :1 , 1993 |
PubMedID: |
Title : Worldwide migration of amplified insecticide resistance genes in mosquitoes. - Raymond_1991_Nature_350_151 |
Author(s) : Raymond M , Callaghan A , Fort P , Pasteur N |
Ref : Nature , 350 :151 , 1991 |
PubMedID: 2005964 |
Title : On the origins of esterases - Myers_1988_Mol.Biol.Evol_5_113 |
Author(s) : Myers M , Richmond RC , Oakeshott JG |
Ref : Molecular Biology Evolution , 5 :113 , 1988 |
PubMedID: 3163407 |
Title : Amplification of an esterase gene is responsible for insecticide resistance in a California Culex mosquito - Mouches_1986_Science_233_778 |
Author(s) : Mouches C , Pasteur N , Berge JB , Hyrien O , Raymond M , de Saint Vincent BR , de Silvestri M , Georghiou GP |
Ref : Science , 233 :778 , 1986 |
PubMedID: 755546 |