multi-kinase inhibitor

A multi-kinase inhibitor (MKI) is a drug that blocks multiple kinases, enzymes crucial for cell signaling, growth, and division, often used in cancer treatment to stop tumor growth, angiogenesis (new blood vessel formation), and metastasis by targeting various pathways simultaneously, offering advantages like higher potency and reduced drug resistance compared to single-target drugs, with examples including sorafenib and lenvatinib used in kidney, liver, and thyroid cancers. Used as building blocks of Multi-target drug ligand MTDL