Author

Biblio print

Tree Display

AceDB Schema

XML Display

Feedback

Author Report for: Zhu KY

Contact information:

Zhu Kevin Y
Division of Life Science, Center for Chinese Medicine and State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology, Clear Water Bay Road, Hong Kong.
China
Phone :
Fax :
Send E-Mail to Zhu Kevin Y





    Title: Comparative analyses of transcriptional responses of Dectes texanus LeConte (Coleoptera: Cerambycidae) larvae fed on three different host plants and artificial diet
    Aguirre-Rojas LM, Scully ED, Trick HN, Zhu KY, Smith CM
    Ref: Sci Rep, 11:11448, 2021 : PubMed

            

    Title: RNA interference: Applications and advances in insect toxicology and insect pest management
    Kim YH, Soumaila Issa M, Cooper AM, Zhu KY
    Ref: Pestic Biochem Physiol, 120:109, 2015 : PubMed

            

    Title: Two homologous carboxylesterase genes from Locusta migratoria with different tissue expression patterns and roles in insecticide detoxification
    Zhang J, Ge P, Li D, Guo Y, Zhu KY, Ma E
    Ref: J Insect Physiol, 77:1, 2015 : PubMed

            

    Title: Authentication of Bulbus Fritillariae Cirrhosae by RAPD-derived DNA markers
    Xin GZ, Lam YC, Maiwulanjiang M, Chan GK, Zhu KY, Tang WL, Dong TTX, Shi ZQ, Li P, Tsim KWK
    Ref: Molecules, 19:3450, 2014 : PubMed

            

    Title: Synergistic Action of Flavonoids, Baicalein, and Daidzein in Estrogenic and Neuroprotective Effects: A Development of Potential Health Products and Therapeutic Drugs against Alzheimer's Disease
    Choi RC, Zhu JT, Yung AW, Lee PS, Xu SL, Guo AJ, Zhu KY, Dong TTX, Tsim KWK
    Ref: Evid Based Complement Alternat Med, 2013:635694, 2013 : PubMed

            

    Title: Song bu li decoction, a traditional uyghur medicine, protects cell death by regulation of oxidative stress and differentiation in cultured PC12 cells
    Maiwulanjiang M, Zhu KY, Chen J, Miernisha A, Xu SL, Du CY, Lau KK, Choi RC, Dong TTX and Tsim KWK <1 more author(s)>
    Ref: Evid Based Complement Alternat Med, 2013:687958, 2013 : PubMed

            

    Title: Flavonoids induce the synthesis and secretion of neurotrophic factors in cultured rat astrocytes: a signaling response mediated by estrogen receptor
    Xu SL, Bi CWC, Choi RC, Zhu KY, Miernisha A, Dong TTX, Tsim KWK
    Ref: Evid Based Complement Alternat Med, 2013:127075, 2013 : PubMed

            

    Title: Flavonoids induce the expression of synaptic proteins, synaptotagmin, and postsynaptic density protein-95 in cultured rat cortical neuron
    Xu SL, Zhu KY, Bi CWC, Choi RC, Miernisha A, Yan AL, Maiwulanjiang M, Men SW, Dong TTX, Tsim KWK
    Ref: Planta Med, 79:1710, 2013 : PubMed

            

    Title: Flavonoids, derived from traditional Chinese medicines, show roles in the differentiation of neurons: possible targets in developing health food products
    Xu SL, Zhu KY, Bi CWC, Yan L, Men SW, Dong TTX, Tsim KWK
    Ref: Birth Defects Res C Embryo Today, 99:292, 2013 : PubMed

            

    Title: Chemical changes of Angelicae Sinensis Radix and Chuanxiong Rhizoma by wine treatment: chemical profiling and marker selection by gas chromatography coupled with triple quadrupole mass spectrometry
    Zhan JY, Zhang WL, Zheng KY, Zhu KY, Chen JP, Chan PH, Dong TTX, Choi RC, Lam H and Lau DT <1 more author(s)>
    Ref: Chin Med, 8:12, 2013 : PubMed

            

    Title: Importance of wine-treated Angelica Sinensis Radix in Si Wu Tang, a traditional herbal formula for treating women's ailments
    Zhan JY, Zheng KY, Zhu KY, Zhang WL, Bi CWC, Chen JP, Du CY, Dong TTX, Lau DT, Tsim KWK
    Ref: Planta Med, 79:533, 2013 : PubMed

            

    Title: RNA interference revealed the roles of two carboxylesterase genes in insecticide detoxification in Locusta migratoria
    Zhang J, Li D, Ge P, Yang M, Guo Y, Zhu KY, Ma E
    Ref: Chemosphere, 93:1207, 2013 : PubMed

            

    Title: Chemical and biological assessment of angelica roots from different cultivated regions in a chinese herbal decoction danggui buxue tang
    Zhang WL, Zheng KY, Zhu KY, Zhan JY, Bi CWC, Chen JP, Dong TTX, Choi RC, Lau DT, Tsim KWK
    Ref: Evid Based Complement Alternat Med, 2013:483286, 2013 : PubMed

            

    Title: Kai-xin-san, a chinese herbal decoction containing ginseng radix et rhizoma, polygalae radix, acori tatarinowii rhizoma, and poria, stimulates the expression and secretion of neurotrophic factors in cultured astrocytes
    Zhu KY, Xu SL, Choi RC, Yan AL, Dong TTX, Tsim KWK
    Ref: Evid Based Complement Alternat Med, 2013:731385, 2013 : PubMed

            

    Title: Can acetylcholinesterase serve as a target for developing more selective insecticides?
    Lang GJ, Zhu KY, Zhang CX
    Ref: Curr Drug Targets, 13:495, 2012 : PubMed

            

    Title: Genome organization, phylogenies, expression patterns, and three-dimensional protein models of two acetylcholinesterase genes from the red flour beetle
    Lu Y, Pang YP, Park Y, Gao X, Yao J, Zhang X, Zhu KY
    Ref: PLoS ONE, 7:e32288, 2012 : PubMed

            

    Title: Cholinergic and non-cholinergic functions of two acetylcholinesterase genes revealed by gene-silencing in Tribolium castaneum
    Lu Y, Park Y, Gao X, Zhang X, Yao J, Pang YP, Jiang H, Zhu KY
    Ref: Sci Rep, 2:288, 2012 : PubMed

            

    Title: Novel and viable acetylcholinesterase target site for developing effective and environmentally safe insecticides
    Pang YP, Brimijoin S, Ragsdale DW, Zhu KY, Suranyi R
    Ref: Curr Drug Targets, 13:471, 2012 : PubMed

            

    Title: [Effects of soybean trypsinase inhibitor and defense signaling compounds on detoxification enzymes in Spodoptera litura (F.) larvae]
    Wu GZ, Hu L, Ye M, Wang RL, Zhu KY, Zeng RS, Cai W
    Ref: Ying Yong Sheng Tai Xue Bao, 23:1952, 2012 : PubMed

            

    Title: Isorhamnetin, A Flavonol Aglycone from Ginkgo biloba L., Induces Neuronal Differentiation of Cultured PC12 Cells: Potentiating the Effect of Nerve Growth Factor
    Xu SL, Choi RC, Zhu KY, Leung KW, Guo AJ, Bi D, Xu H, Lau DT, Dong TTX, Tsim KWK
    Ref: Evid Based Complement Alternat Med, 2012:278273, 2012 : PubMed

            

    Title: Chemical and biological assessment of Angelica herbal decoction: comparison of different preparations during historical applications
    Zhang WL, Zheng KY, Zhu KY, Zhan JY, Bi CWC, Chen JP, Du CY, Zhao KJ, Lau DT and Tsim KWK <1 more author(s)>
    Ref: Phytomedicine, 19:1042, 2012 : PubMed

            

    Title: The membrane permeability of Astragali Radix-derived formononetin and calycosin is increased by Angelicae Sinensis Radix in Caco-2 cells: a synergistic action of an ancient herbal decoction Danggui Buxue Tang
    Zheng KY, Choi RC, Guo AJ, Bi CWC, Zhu KY, Du CY, Zhang ZX, Lau DT, Dong TTX, Tsim KWK
    Ref: J Pharm Biomed Anal, 70:671, 2012 : PubMed

            

    Title: Salidroside stimulates the accumulation of HIF-1alpha protein resulted in the induction of EPO expression: a signaling via blocking the degradation pathway in kidney and liver cells
    Zheng KY, Zhang ZX, Guo AJ, Bi CWC, Zhu KY, Xu SL, Zhan JY, Lau DT, Dong TTX and Tsim KWK <1 more author(s)>
    Ref: European Journal of Pharmacology, 679:34, 2012 : PubMed

            

    Title: A standardized chinese herbal decoction, kai-xin-san, restores decreased levels of neurotransmitters and neurotrophic factors in the brain of chronic stress-induced depressive rats
    Zhu KY, Mao QQ, Ip SP, Choi RC, Dong TTX, Lau DT, Tsim KWK
    Ref: Evid Based Complement Alternat Med, 2012:149256, 2012 : PubMed

            

    Title: Chemical and biological assessment of Angelicae Sinensis Radix after processing with wine: an orthogonal array design to reveal the optimized conditions
    Zhan JY, Zheng KY, Zhu KY, Bi CWC, Zhang WL, Du CY, Fu Q, Dong TTX, Choi RC and Lau DT <1 more author(s)>
    Ref: Journal of Agricultural and Food Chemistry, 59:6091, 2011 : PubMed

            

    Title: Genomics-based approaches to screening carboxylesterase-like genes potentially involved in malathion resistance in oriental migratory locust (Locusta migratoria manilensis)
    Zhang J, Yang M, Jia Q, Guo Y, Ma E, Zhu KY
    Ref: Pest Manag Sci, 67:183, 2011 : PubMed

            

    Title: Flavonoids from Radix Astragali induce the expression of erythropoietin in cultured cells: a signaling mediated via the accumulation of hypoxia-inducible factor-1alpha
    Zheng KY, Choi RC, Cheung AW, Guo AJ, Bi CWC, Zhu KY, Fu Q, Du Y, Zhang WL and Tsim KWK <4 more author(s)>
    Ref: Journal of Agricultural and Food Chemistry, 59:1697, 2011 : PubMed

            

    Title: The extract of Rhodiolae Crenulatae Radix et Rhizoma induces the accumulation of HIF-1alpha via blocking the degradation pathway in cultured kidney fibroblasts
    Zheng KY, Guo AJ, Bi CWC, Zhu KY, Chan GK, Fu Q, Xu SL, Zhan JY, Lau DT and Tsim KWK <2 more author(s)>
    Ref: Planta Med, 77:894, 2011 : PubMed

            

    Title: Major putative pesticide receptors, detoxification enzymes, and transcriptional profile of the midgut of the tobacco budworm, Heliothis virescens (Lepidoptera: Noctuidae)
    Zhu YC, Guo Z, Chen MS, Zhu KY, Liu XF, Scheffler B
    Ref: J Invertebr Pathol, 106:296, 2011 : PubMed

            

    Title: Expression and Localization of PRiMA-linked globular form acetylcholinesterase in vertebrate neuromuscular junctions
    Tsim KWK, Leung KW, Mok KW, Chen VP, Zhu KY, Zhu JT, Guo AJ, Bi CWC, Zheng KY and Choi RC <2 more author(s)>
    Ref: Journal of Molecular Neuroscience, 40:40, 2010 : PubMed

            

    Title: PRiMA directs a restricted localization of tetrameric AChE at synapses
    Xie HQ, Leung KW, Chen VP, Chan GK, Xu SL, Guo AJ, Zhu KY, Zheng KY, Bi CWC and Tsim KWK <3 more author(s)>
    Ref: Chemico-Biological Interactions, 187:78, 2010 : PubMed

            

    Title: Targeting acetylcholinesterase to membrane rafts: a function mediated by the proline-rich membrane anchor (PRiMA) in neurons
    Xie HQ, Liang D, Leung KW, Chen VP, Zhu KY, Chan WK, Choi RC, Massoulie J, Tsim KWK
    Ref: Journal of Biological Chemistry, 285:11537, 2010 : PubMed

            

    Title: Heterologous expression, purification, and biochemical characterization of a greenbug (Schizaphis graminum) acetylcholinesterase encoded by a paralogous gene (ace-1)
    Zhao P, Zhu KY, Jiang H
    Ref: J Biochem Mol Toxicol, 24:51, 2010 : PubMed

            

    Title: The expression of erythropoietin triggered by danggui buxue tang, a Chinese herbal decoction prepared from radix Astragali and radix Angelicae Sinensis, is mediated by the hypoxia-inducible factor in cultured HEK293T cells
    Zheng KY, Choi RC, Xie HQ, Cheung AW, Guo AJ, Leung KW, Chen VP, Bi CWC, Zhu KY and Tsim KWK <5 more author(s)>
    Ref: J Ethnopharmacol, 132:259, 2010 : PubMed

            

    Title: Quality assessment of a formulated Chinese herbal decoction, Kaixinsan, by using rapid resolution liquid chromatography coupled with mass spectrometry: A chemical evaluation of different historical formulae
    Zhu KY, Fu Q, Xie HQ, Xu SL, Cheung AW, Zheng KY, Luk WK, Choi RC, Lau DT and Tsim KWK <3 more author(s)>
    Ref: J Sep Sci, 33:3666, 2010 : PubMed

            

    Title: Selective and irreversible inhibitors of aphid acetylcholinesterases: steps toward human-safe insecticides
    Pang YP, Singh SK, Gao Y, Lassiter TL, Mishra RK, Zhu KY, Brimijoin S
    Ref: PLoS ONE, 4:e4349, 2009 : PubMed

            

    Title: Selective and irreversible inhibitors of mosquito acetylcholinesterases for controlling malaria and other mosquito-borne diseases
    Pang YP, Ekstrom F, Polsinelli GA, Gao Y, Rana S, Hua DH, Andersson B, Andersson PO, Peng L and Brimijoin S <5 more author(s)>
    Ref: PLoS ONE, 4:e6851, 2009 : PubMed

            

    Title: Mechanisms of organophosphate resistance in a field population of oriental migratory locust, Locusta migratoria manilensis (Meyen)
    Yang ML, Zhang JZ, Zhu KY, Xuan T, Liu XJ, Guo YP, Ma EB
    Ref: Archives of Insect Biochemistry & Physiology, 71:3, 2009 : PubMed

            

    Title: Effect of alachlor and metolachlor on toxicity of chlorpyrifos and major detoxification enzymes in the aquatic midge, Chironomus tentans (Diptera: Chironomidae)
    Jin-Clark Y, Anderson TD, Zhu KY
    Ref: Archives of Environmental Contamination & Toxicology, 54:645, 2008 : PubMed

            

    Title: Increased activity and reduced sensitivity of acetylcholinesterase associated with malathion resistance in a field population of the oriental migratory locust, Locusta migratoria manilensis (Meyen)
    Yang M, Zhang J, Zhu KY, Xuan T, Liu X, Guo Y, Ma E
    Ref: Pesticide Biochemistry and Physiology, 91:32, 2008 : PubMed

            

    Title: Sublethal effects of three pesticides on activities of selected target and detoxification enzymes in the aquatic midge, Chironomus tentans (diptera: chironomidae)
    Rakotondravelo ML, Anderson TD, Charlton RE, Zhu KY
    Ref: Archives of Environmental Contamination & Toxicology, 51:360, 2006 : PubMed

            

    Title: Synergistic and antagonistic effects of atrazine on the toxicity of organophosphorodithioate and organophosphorothioate insecticides to Chironomus tentans (Diptera: Chironomidae)
    Anderson TD, Zhu KY
    Ref: Pesticide Biochemistry and Physiology, 80:54, 2004 : PubMed

            

    Title: Characterizations of general esterases in relation to malathion susceptibility in two field populations of the oriental migratory locust, Locusta migratoria manilensis (Meyen)
    He Y-P, Ma E-B, Zhu KY
    Ref: Pesticide Biochemistry and Physiology, 78:103, 2004 : PubMed

            

    Title: Comparative studies of acetylcholinesterases purified from two field populations of the oriental migratory locust (Locusta migratoria manilensis): implications of insecticide resistance
    Ma EB, He YP, Zhu KY
    Ref: Pesticide Biochemistry and Physiology, 78:67, 2004 : PubMed

            

    Title: Molecular cloning and characterization of a greenbug (Schizaphis graminum) cDNA encoding acetylcholinesterase possibly evolved from a duplicate gene lineage
    Gao JR, Kambhampati S, Zhu KY
    Ref: Insect Biochemistry & Molecular Biology, 32:765, 2002 : PubMed

            

    Title: Increased expression of an acetylcholinesterase gene may confer organophosphate resistance in the greenbug, Schizaphis graminum (Homoptera: Aphididae)
    Gao JR, Zhu KY
    Ref: Pesticide Biochemistry and Physiology, 73:164, 2002 : PubMed

            

    Title: Effects of atrazine and cyanazine on chlorpyrifos toxicity in Chironomus tentans (Diptera: Chironomidae)
    Jin-Clark Y, Lydy MJ, Zhu KY
    Ref: Environ Toxicol Chem, 21:598, 2002 : PubMed

            

    Title: An acetylcholinesterase purified from the greenbug (Schizaphis graminum) with some unique enzymological and pharmacological characteristics
    Gao J, Zhu KY, Gao JR
    Ref: Insect Biochemistry & Molecular Biology, 31:1095, 2001 : PubMed

            

    Title: Host plant-induced changes in detoxification enzymes and susceptibility to pesticides in the twospotted spider mite (Acari: Tetranychidae)
    Yang X, Margolies DC, Zhu KY, Buschman LL
    Ref: J Econ Entomol, 94:381, 2001 : PubMed

            

    Title: Comparative toxicity of selected organophosphate insecticides against resistant and susceptible clones of the greenbug, Schizaphis graminum (Homoptera: aphididae)
    Gao JR, Zhu KY
    Ref: Journal of Agricultural and Food Chemistry, 48:4717, 2000 : PubMed

            

    Title: Alterations in esterases are associated with malathion resistance in Habrobracon hebetor (Hymenoptera: Braconidae)
    Perez-Mendoza J, Fabrick JA, Zhu KY, Baker JE
    Ref: J Econ Entomol, 93:31, 2000 : PubMed

            

    Title: Organophosphate Resistance Mediated by Alterations of Acetylcholinesterase in a Resistant Clone of the Greenbug, Schizaphis graminum (Homoptera: Aphididae)
    Zhu KY, Gao JR, Starkey SR
    Ref: Pesticide Biochemistry and Physiology, 68:138, 2000 : PubMed

            

    Title: Elevated Esterases Exhibiting Arylesterase-like Characteristics in an Organophosphate-Resistant Clone of the Greenbug, Schizaphis graminum (Homoptera: Aphididae)
    Zhu KY, He F
    Ref: Pesticide Biochemistry and Physiology, 67:155, 2000 : PubMed

            

    Title: Purification and kinetic analysis of acetylcholinesterase from western corn rootworm, Diabrotica virgifera virgifera (Coleoptera: Chrysomelidae)
    Gao JR, Rao JV, Wilde GE, Zhu KY
    Ref: Archives of Insect Biochemistry & Physiology, 39:118, 1998 : PubMed

            

    Title: Characterization of acetylcholinesterase purified from the lesser grain borer, Rhyzopertha dominica (Coleoptera: Bostrichidae)
    Guedes RN, Zhu KY, Kambhampati S, Dover BA
    Ref: Comparative Biochemistry & Physiology C Pharmacol Toxicol Endocrinol, 119:205, 1998 : PubMed

            

    Title: Characterization of malathion resistance in a Mexican population of Rhizopertha dominica
    Guedes RNC, Zhu KY
    Ref: Pest Sci, 53:15, 1998 : PubMed

            

    Title: Kinetic Properties and Variability of Esterases in Organophosphate-Susceptible and -Resistant Greenbugs, Schizaphis graminum (Homoptera: Aphididae)
    Zhu KY, Gao JR
    Ref: Pesticide Biochemistry and Physiology, 62:135, 1998 : PubMed

            

    Title: An Altered Acetylcholinesterase Conferring Negative Cross-Insensitivity to Different Insecticidal Inhibitors in Organophosphate-Resistant Lesser Grain Borer,Rhyzopertha dominica
    Guedes RN, Zhu KY, Kambhampati S, Dover BA
    Ref: Pesticide Biochemistry and Physiology, 58:55, 1997 : PubMed

            

    Title: Validation of a Point Mutation of Acetylcholinesterase in Colorado Potato Beetle by Polymerase Chain Reaction Coupled to Enzyme Inhibition Assay
    Zhu KY, Clark JM
    Ref: Pesticide Biochemistry and Physiology, 57:28, 1997 : PubMed

            

    Title: A Point Mutation of Acetylcholinesterase Associated with Azinphosmethyl Resistance and Reduced Fitness in Colorado Potato Beetle
    Zhu KY, Lee SH, Clark JM
    Ref: Pestic Biochem Physiol, 55:100, 1996 : PubMed

            

    Title: Comparisons of Kinetic Properties of Acetylcholinesterase Purified from Azinphosmethyl-Susceptible and Resistant Strains of Colorado Potato Beetle
    Zhu KY, Clark JM
    Ref: Pesticide Biochemistry and Physiology, 51:57, 1995 : PubMed

            

    Title: Cloning and sequencing of a cdna encoding acetylcholinesterase in Colorado potato beetle, Leptinotarsa decemlineata (Say)
    Zhu KY, Clark JM
    Ref: Insect Biochemistry & Molecular Biology, 25 (10):1129, 1995 : PubMed

            

    Title: Biochemical Mechanisms of Azinphosmethyl Resistance in Isogenic Strains of Colorado Potato Beetle
    Argentine JA, Zhu KY, Lee SH, Clark JM
    Ref: Pesticide Biochemistry and Physiology, 48:63, 1994 : PubMed

            

    Title: Purification and characterization of acetylcholinesterase from the Colorado potato beetle, Leptinotarsa decemlineata (Say)
    Zhu KY, Clark JM
    Ref: Insect Biochemistry & Molecular Biology, 24:453, 1994 : PubMed

            

    Title: Significance of carboxylesterases and insensitive acetylcholinesterase in conferring organophosphate resistance in Lygus hesperus populations
    Zhu KY, Brindley WA
    Ref: Pesticide Biochemistry and Physiology, 43:223, 1992 : PubMed

            

    Title: Acetylcholinesterase and its reduced sensitivity to inhibition by paraoxon in organophosphate-resistant Lygus hesperus knight (Hemiptera: Miridae)
    Zhu KY, Brindley WA
    Ref: Pesticide Biochemistry and Physiology, 36:22, 1990 : PubMed

            


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page
webmaster

Acknowledgements and disclaimer