| Title : ABCB1 attenuates brain exposure to the KRAS(G12C) inhibitor opnurasib whereas binding to mouse carboxylesterase 1c influences its plasma exposure - Rijmers_2024_Biomed.Pharmacother_175_116720 |
| Author(s) : Rijmers J , Retmana IA , Bui V , Arguedas D , Lebre MC , Sparidans RW , Beijnen JH , Schinkel AH |
| Ref : Biomed Pharmacother , 175 :116720 , 2024 |
| Abstract : |
| PubMedSearch : Rijmers_2024_Biomed.Pharmacother_175_116720 |
| PubMedID: 38733773 |
| Title : Pharmacokinetics of the KRAS(G12C) inhibitor adagrasib is limited by CYP3A and ABCB1, and influenced by binding to mouse plasma carboxylesterase 1c - Loos_2023_Biomed.Pharmacother_166_115304 |
| Author(s) : Loos NHC , Retmana IA , Rijmers J , Wang Y , Gan C , Lebre MC , Sparidans RW , Beijnen JH , Schinkel AH |
| Ref : Biomed Pharmacother , 166 :115304 , 2023 |
| Abstract : |
| PubMedSearch : Loos_2023_Biomed.Pharmacother_166_115304 |
| PubMedID: 37586117 |