Title : From structure to clinic: Design of a muscarinic M1 receptor agonist with potential to treatment of Alzheimer's disease - Brown_2021_Cell_184_5886 |
Author(s) : Brown AJH , Bradley SJ , Marshall FH , Brown GA , Bennett KA , Brown J , Cansfield JE , Cross DM , de Graaf C , Hudson BD , Dwomoh L , Dias JM , Errey JC , Hurrell E , Liptrot J , Mattedi G , Molloy C , Nathan PJ , Okrasa K , Osborne G , Patel JC , Pickworth M , Robertson N , Shahabi S , Bundgaard C , Phillips K , Broad LM , Goonawardena AV , Morairty SR , Browning M , Perini F , Dawson GR , Deakin JFW , Smith RT , Sexton PM , Warneck J , Vinson M , Tasker T , Tehan BG , Teobald B , Christopoulos A , Langmead CJ , Jazayeri A , Cooke RM , Rucktooa P , Congreve MS , Weir M , Tobin AB |
Ref : Cell , 184 :5886 , 2021 |
Abstract : |
PubMedSearch : Brown_2021_Cell_184_5886 |
PubMedID: 34822784 |
Title : The 5-HT6 receptor antagonist idalopirdine potentiates the effects of donepezil on gamma oscillations in the frontal cortex of anesthetized and awake rats without affecting sleep-wake architecture - Amat-Foraster_2016_Neuropharmacol_113_45 |
Author(s) : Amat-Foraster M , Leiser SC , Herrik KF , Richard N , Agerskov C , Bundgaard C , Bastlund JF , de Jong IE |
Ref : Neuropharmacology , 113 :45 , 2016 |
Abstract : |
PubMedSearch : Amat-Foraster_2016_Neuropharmacol_113_45 |
PubMedID: 27647493 |
Title : The 5-HT receptor antagonist idalopirdine potentiates the effects of acetylcholinesterase inhibition on neuronal network oscillations and extracellular acetylcholine levels in the rat dorsal hippocampus - Herrik_2016_Neuropharmacol_107_351 |
Author(s) : Herrik KF , Mork A , Richard N , Bundgaard C , Bastlund JF , de Jong IE |
Ref : Neuropharmacology , 107 :351 , 2016 |
Abstract : |
PubMedSearch : Herrik_2016_Neuropharmacol_107_351 |
PubMedID: 27039041 |
Title : Poster: Antipsychotic compounds show inhibition of the human nicotinic acetylcholine alpha-7 receptor at high concentrations - |
Author(s) : Frederiksen K , Bundgaard C , Dekermendjian K , Redrobe JP , FullertonStoier J , Eskildsen J , Bastlund JF |
Ref : Biochemical Pharmacology , 86 :1226 , 2013 |
PubMedID: |
Title : Poster: Discovery of Lu AF58801, a novel, selective and brain penetrant positive allosteric modulator of alpha-7 nicotinic acetylcholine receptors: Attenuation of subchronic phencyclidine (PCP)-induced cognitive deficits in rats following oral administration - |
Author(s) : Bastlund JF , Bundgaard C , Dekermendjian K , Papke RL , Redrobe JP , Frederiksen K , Eskildsen J |
Ref : Biochemical Pharmacology , 86 :1231 , 2013 |
PubMedID: |