| Title : From structure to clinic: Design of a muscarinic M1 receptor agonist with potential to treatment of Alzheimer's disease - Brown_2021_Cell_184_5886 |
| Author(s) : Brown AJH , Bradley SJ , Marshall FH , Brown GA , Bennett KA , Brown J , Cansfield JE , Cross DM , de Graaf C , Hudson BD , Dwomoh L , Dias JM , Errey JC , Hurrell E , Liptrot J , Mattedi G , Molloy C , Nathan PJ , Okrasa K , Osborne G , Patel JC , Pickworth M , Robertson N , Shahabi S , Bundgaard C , Phillips K , Broad LM , Goonawardena AV , Morairty SR , Browning M , Perini F , Dawson GR , Deakin JFW , Smith RT , Sexton PM , Warneck J , Vinson M , Tasker T , Tehan BG , Teobald B , Christopoulos A , Langmead CJ , Jazayeri A , Cooke RM , Rucktooa P , Congreve MS , Weir M , Tobin AB |
| Ref : Cell , 184 :5886 , 2021 |
| Abstract : |
| PubMedSearch : Brown_2021_Cell_184_5886 |
| PubMedID: 34822784 |
| Title : Acetylcholine binding protein (AChBP) as template for hierarchical in silico screening procedures to identify structurally novel ligands for the nicotinic receptors - Akdemir_2011_Bioorg.Med.Chem_19_6107 |
| Author(s) : Akdemir A , Rucktooa P , Jongejan A , Elk R , Bertrand S , Sixma TK , Bertrand D , Smit AB , Leurs R , de Graaf C , de Esch IJ |
| Ref : Bioorganic & Medicinal Chemistry , 19 :6107 , 2011 |
| Abstract : |
| PubMedSearch : Akdemir_2011_Bioorg.Med.Chem_19_6107 |
| PubMedID: 21920761 |