| Title : Novel 6-alkyl-bridged 4-arylalkylpiperazin-1-yl derivatives of azepino[4,3-b]indol-1(2H)-one as potent BChE-selective inhibitors showing protective effects against neurodegenerative insults - Samarelli_2024_Eur.J.Med.Chem_270_116353 |
| Author(s) : Samarelli F , Purgatorio R , Lopopolo G , Deruvo C , Catto M , Andresini M , Carrieri A , Nicolotti O , De Palma A , Miniero DV , de Candia M , Altomare CD |
| Ref : Eur Journal of Medicinal Chemistry , 270 :116353 , 2024 |
| Abstract : |
| PubMedSearch : Samarelli_2024_Eur.J.Med.Chem_270_116353 |
| PubMedID: 38579622 |
| Title : Structure-based design of multitargeting ChEs-MAO B inhibitors based on phenyl ring bioisosteres: AChE\/BChE selectivity switch and drug-like characterization - La Spada_2024_Eur.J.Med.Chem_274_116511 |
| Author(s) : La Spada G , Miniero DV , Rullo M , Cipolloni M , Delre P , Colliva C , Colella M , Leonetti F , Liuzzi GM , Mangiatordi GF , Giacche N , Pisani L |
| Ref : Eur Journal of Medicinal Chemistry , 274 :116511 , 2024 |
| Abstract : |
| PubMedSearch : La Spada_2024_Eur.J.Med.Chem_274_116511 |
| PubMedID: 38820854 |
| Title : Thioxanthenone-based derivatives as multitarget therapeutic leads for Alzheimer's disease - Tonelli_2023_Eur.J.Med.Chem_250_115169 |
| Author(s) : Tonelli M , Catto M , Sabate R , Francesconi V , Laurini E , Pricl S , Pisani L , Miniero DV , Liuzzi GM , Gatta E , Relini A , Gavin R , Del Rio JA , Sparatore F , Carotti A |
| Ref : Eur Journal of Medicinal Chemistry , 250 :115169 , 2023 |
| Abstract : |
| PubMedSearch : Tonelli_2023_Eur.J.Med.Chem_250_115169 |
| PubMedID: 36753881 |
| Title : Mannich base approach to 5-methoxyisatin 3-(4-isopropylphenyl)hydrazone: A water-soluble prodrug for a multitarget inhibition of cholinesterases, beta-amyloid fibrillization and oligomer-induced cytotoxicity - Pisani_2017_Eur.J.Pharm.Sci_109_381 |
| Author(s) : Pisani L , De Palma A , Giangregorio N , Miniero DV , Pesce P , Nicolotti O , Campagna F , Altomare CD , Catto M |
| Ref : Eur J Pharm Sci , 109 :381 , 2017 |
| Abstract : |
| PubMedSearch : Pisani_2017_Eur.J.Pharm.Sci_109_381 |
| PubMedID: 28801274 |