| Title : Identification of a New, Potent, and Stable Tetrahydroquinoline-Based 5-LOX\/sEH Dual Inhibitor with Polymodal Anti-Inflammatory Activity in Acute Pancreatitis - D'Avino_2026_J.Med.Chem__ |
| Author(s) : D'Avino D , Ciaglia T , Jordan PM , Di Micco S , Musella S , Di Sarno V , Merciai F , Perna S , Smaldone G , Di Matteo F , Napolitano V , Stimoli R , Sardo I , Ricci O , Bifulco G , Sommella EM , Basilicata MG , Ferrara G , Roviezzo F , Di Dio A , Aquino G , Pellecchia S , Pepe G , Gomez-Monterrey IM , Campiglia P , Ostacolo C , Manfra M , Werz O , Rossi A , Bertamino A |
| Ref : Journal of Medicinal Chemistry , : , 2026 |
| Abstract : |
| PubMedSearch : D'Avino_2026_J.Med.Chem__ |
| PubMedID: 42504850 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : Reorganization of Innate Immune Cell Lipid Profiles by Bioinspired Meroterpenoids to Limit Inflammation - Waltl_2026_Adv.Sci.(Weinh)__e76861 |
| Author(s) : Waltl L , Holubek D , Speck K , Wildermuth R , Haut FL , Permann S , Plangger I , Steinborn C , Rao Z , D'Avino D , Cerqua I , Stadler J , Roviezzo F , Schlenke P , Siller A , Schennach H , Koeberle SC , Pferschy-Wenzig EM , Rossi A , Magauer T , Koeberle A |
| Ref : Adv Sci (Weinh) , :e76861 , 2026 |
| Abstract : |
| PubMedSearch : Waltl_2026_Adv.Sci.(Weinh)__e76861 |
| PubMedID: 42610641 |
| Title : An adamantylureido-benzylamide aniline as FLAP\/sEH dual inhibitor: Rational design, in vitro and in vivo lipidomic profiling - Ciaglia_2025_Eur.J.Med.Chem_302_118338 |
| Author(s) : Ciaglia T , D'Avino D , Jordan PM , Di Micco S , Musella S , Engelbrecht H , Peltner LK , Di Sarno V , Merciai F , Perna S , Smaldone G , Di Matteo F , Napolitano V , Stimoli R , Bifulco G , Pepe G , Sommella EM , Basilicata MG , Aquino G , Gomez-Monterrey IM , Campiglia P , Ostacolo C , Werz O , Rossi A , Bertamino A , Manfra M |
| Ref : Eur Journal of Medicinal Chemistry , 302 :118338 , 2025 |
| Abstract : |
| PubMedSearch : Ciaglia_2025_Eur.J.Med.Chem_302_118338 |
| PubMedID: 41197472 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : Design, Synthesis, and Pharmacological Characterization of a Potent Soluble Epoxide Hydrolase Inhibitor for the Treatment of Acute Pancreatitis - Musella_2023_J.Med.Chem__ |
| Author(s) : Musella S , D'Avino D , Peltner LK , Di Sarno V , Cerqua I , Merciai F , Vestuto V , Ciaglia T , Smaldone G , Di Matteo F , Di Micco S , Napolitano V , Bifulco G , Pepe G , Sommella EM , Basilicata MG , Aquino G , Gomez-Monterrey IM , Campiglia P , Ostacolo C , Roviezzo F , Werz O , Rossi A , Bertamino A |
| Ref : Journal of Medicinal Chemistry , : , 2023 |
| Abstract : |
| PubMedSearch : Musella_2023_J.Med.Chem__ |
| PubMedID: 37334504 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : Discovery and Optimization of Indoline-Based Compounds as Dual 5-LOX\/sEH Inhibitors: In Vitro and In Vivo Anti-Inflammatory Characterization - Cerqua_2022_J.Med.Chem__ |
| Author(s) : Cerqua I , Musella S , Peltner LK , D'Avino D , Di Sarno V , Granato E , Vestuto V , Di Matteo R , Pace S , Ciaglia T , Bilancia R , Smaldone G , Di Matteo F , Di Micco S , Bifulco G , Pepe G , Basilicata MG , Rodriquez M , Gomez-Monterrey IM , Campiglia P , Ostacolo C , Roviezzo F , Werz O , Rossi A , Bertamino A |
| Ref : Journal of Medicinal Chemistry , : , 2022 |
| Abstract : |
| PubMedSearch : Cerqua_2022_J.Med.Chem__ |
| PubMedID: 36318728 |