| Title : An adamantylureido-benzylamide aniline as FLAP\/sEH dual inhibitor: Rational design, in vitro and in vivo lipidomic profiling - Ciaglia_2025_Eur.J.Med.Chem_302_118338 |
| Author(s) : Ciaglia T , D'Avino D , Jordan PM , Di Micco S , Musella S , Engelbrecht H , Peltner LK , Di Sarno V , Merciai F , Perna S , Smaldone G , Di Matteo F , Napolitano V , Stimoli R , Bifulco G , Pepe G , Sommella EM , Basilicata MG , Aquino G , Gomez-Monterrey IM , Campiglia P , Ostacolo C , Werz O , Rossi A , Bertamino A , Manfra M |
| Ref : Eur Journal of Medicinal Chemistry , 302 :118338 , 2025 |
| Abstract : |
| PubMedSearch : Ciaglia_2025_Eur.J.Med.Chem_302_118338 |
| PubMedID: 41197472 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : An adamantylureido-benzylamide aniline as FLAP\/sEH dual inhibitor: Rational design, in vitro and in vivo lipidomic profiling - Ciaglia_2025_Eur.J.Med.Chem_302_118338 |
| Author(s) : Ciaglia T , D'Avino D , Jordan PM , Di Micco S , Musella S , Engelbrecht H , Peltner LK , Di Sarno V , Merciai F , Perna S , Smaldone G , Di Matteo F , Napolitano V , Stimoli R , Bifulco G , Pepe G , Sommella EM , Basilicata MG , Aquino G , Gomez-Monterrey IM , Campiglia P , Ostacolo C , Werz O , Rossi A , Bertamino A , Manfra M |
| Ref : Eur Journal of Medicinal Chemistry , 302 :118338 , 2025 |
| Abstract : |
| PubMedSearch : Ciaglia_2025_Eur.J.Med.Chem_302_118338 |
| PubMedID: 41197472 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : An adamantylureido-benzylamide aniline as FLAP\/sEH dual inhibitor: Rational design, in vitro and in vivo lipidomic profiling - Ciaglia_2025_Eur.J.Med.Chem_302_118338 |
| Author(s) : Ciaglia T , D'Avino D , Jordan PM , Di Micco S , Musella S , Engelbrecht H , Peltner LK , Di Sarno V , Merciai F , Perna S , Smaldone G , Di Matteo F , Napolitano V , Stimoli R , Bifulco G , Pepe G , Sommella EM , Basilicata MG , Aquino G , Gomez-Monterrey IM , Campiglia P , Ostacolo C , Werz O , Rossi A , Bertamino A , Manfra M |
| Ref : Eur Journal of Medicinal Chemistry , 302 :118338 , 2025 |
| Abstract : |
| PubMedSearch : Ciaglia_2025_Eur.J.Med.Chem_302_118338 |
| PubMedID: 41197472 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : Biomarker responses in fish caged in a rice field during a bifenthrin application - Cazenave_2024_Environ.Res__120240 |
| Author(s) : Cazenave J , Bacchetta C , Repetti MR , Rossi A |
| Ref : Environ Research , :120240 , 2024 |
| Abstract : |
| PubMedSearch : Cazenave_2024_Environ.Res__120240 |
| PubMedID: 39490548 |
| Title : Biomarker responses in fish caged in a rice field during a bifenthrin application - Cazenave_2024_Environ.Res__120240 |
| Author(s) : Cazenave J , Bacchetta C , Repetti MR , Rossi A |
| Ref : Environ Research , :120240 , 2024 |
| Abstract : |
| PubMedSearch : Cazenave_2024_Environ.Res__120240 |
| PubMedID: 39490548 |
| Title : Biomarker responses in fish caged in a rice field during a bifenthrin application - Cazenave_2024_Environ.Res__120240 |
| Author(s) : Cazenave J , Bacchetta C , Repetti MR , Rossi A |
| Ref : Environ Research , :120240 , 2024 |
| Abstract : |
| PubMedSearch : Cazenave_2024_Environ.Res__120240 |
| PubMedID: 39490548 |
| Title : Design, Synthesis, and Pharmacological Characterization of a Potent Soluble Epoxide Hydrolase Inhibitor for the Treatment of Acute Pancreatitis - Musella_2023_J.Med.Chem__ |
| Author(s) : Musella S , D'Avino D , Peltner LK , Di Sarno V , Cerqua I , Merciai F , Vestuto V , Ciaglia T , Smaldone G , Di Matteo F , Di Micco S , Napolitano V , Bifulco G , Pepe G , Sommella EM , Basilicata MG , Aquino G , Gomez-Monterrey IM , Campiglia P , Ostacolo C , Roviezzo F , Werz O , Rossi A , Bertamino A |
| Ref : Journal of Medicinal Chemistry , : , 2023 |
| Abstract : |
| PubMedSearch : Musella_2023_J.Med.Chem__ |
| PubMedID: 37334504 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : Design, Synthesis, and Pharmacological Characterization of a Potent Soluble Epoxide Hydrolase Inhibitor for the Treatment of Acute Pancreatitis - Musella_2023_J.Med.Chem__ |
| Author(s) : Musella S , D'Avino D , Peltner LK , Di Sarno V , Cerqua I , Merciai F , Vestuto V , Ciaglia T , Smaldone G , Di Matteo F , Di Micco S , Napolitano V , Bifulco G , Pepe G , Sommella EM , Basilicata MG , Aquino G , Gomez-Monterrey IM , Campiglia P , Ostacolo C , Roviezzo F , Werz O , Rossi A , Bertamino A |
| Ref : Journal of Medicinal Chemistry , : , 2023 |
| Abstract : |
| PubMedSearch : Musella_2023_J.Med.Chem__ |
| PubMedID: 37334504 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : Design, Synthesis, and Pharmacological Characterization of a Potent Soluble Epoxide Hydrolase Inhibitor for the Treatment of Acute Pancreatitis - Musella_2023_J.Med.Chem__ |
| Author(s) : Musella S , D'Avino D , Peltner LK , Di Sarno V , Cerqua I , Merciai F , Vestuto V , Ciaglia T , Smaldone G , Di Matteo F , Di Micco S , Napolitano V , Bifulco G , Pepe G , Sommella EM , Basilicata MG , Aquino G , Gomez-Monterrey IM , Campiglia P , Ostacolo C , Roviezzo F , Werz O , Rossi A , Bertamino A |
| Ref : Journal of Medicinal Chemistry , : , 2023 |
| Abstract : |
| PubMedSearch : Musella_2023_J.Med.Chem__ |
| PubMedID: 37334504 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : Discovery and Optimization of Indoline-Based Compounds as Dual 5-LOX\/sEH Inhibitors: In Vitro and In Vivo Anti-Inflammatory Characterization - Cerqua_2022_J.Med.Chem__ |
| Author(s) : Cerqua I , Musella S , Peltner LK , D'Avino D , Di Sarno V , Granato E , Vestuto V , Di Matteo R , Pace S , Ciaglia T , Bilancia R , Smaldone G , Di Matteo F , Di Micco S , Bifulco G , Pepe G , Basilicata MG , Rodriquez M , Gomez-Monterrey IM , Campiglia P , Ostacolo C , Roviezzo F , Werz O , Rossi A , Bertamino A |
| Ref : Journal of Medicinal Chemistry , : , 2022 |
| Abstract : |
| PubMedSearch : Cerqua_2022_J.Med.Chem__ |
| PubMedID: 36318728 |
| Title : Discovery and Optimization of Indoline-Based Compounds as Dual 5-LOX\/sEH Inhibitors: In Vitro and In Vivo Anti-Inflammatory Characterization - Cerqua_2022_J.Med.Chem__ |
| Author(s) : Cerqua I , Musella S , Peltner LK , D'Avino D , Di Sarno V , Granato E , Vestuto V , Di Matteo R , Pace S , Ciaglia T , Bilancia R , Smaldone G , Di Matteo F , Di Micco S , Bifulco G , Pepe G , Basilicata MG , Rodriquez M , Gomez-Monterrey IM , Campiglia P , Ostacolo C , Roviezzo F , Werz O , Rossi A , Bertamino A |
| Ref : Journal of Medicinal Chemistry , : , 2022 |
| Abstract : |
| PubMedSearch : Cerqua_2022_J.Med.Chem__ |
| PubMedID: 36318728 |
| Title : Discovery and Optimization of Indoline-Based Compounds as Dual 5-LOX\/sEH Inhibitors: In Vitro and In Vivo Anti-Inflammatory Characterization - Cerqua_2022_J.Med.Chem__ |
| Author(s) : Cerqua I , Musella S , Peltner LK , D'Avino D , Di Sarno V , Granato E , Vestuto V , Di Matteo R , Pace S , Ciaglia T , Bilancia R , Smaldone G , Di Matteo F , Di Micco S , Bifulco G , Pepe G , Basilicata MG , Rodriquez M , Gomez-Monterrey IM , Campiglia P , Ostacolo C , Roviezzo F , Werz O , Rossi A , Bertamino A |
| Ref : Journal of Medicinal Chemistry , : , 2022 |
| Abstract : |
| PubMedSearch : Cerqua_2022_J.Med.Chem__ |
| PubMedID: 36318728 |
| Title : Multibiomarker responses in Danio rerio after exposure to sediment spiked with triclosan - Sager_2021_An.Acad.Bras.Cienc_93_e20201938 |
| Author(s) : Sager E , Rossi A , Loughlin TM , Marino D , Torre F |
| Ref : An Acad Bras Cienc , 93 :e20201938 , 2021 |
| Abstract : |
| PubMedSearch : Sager_2021_An.Acad.Bras.Cienc_93_e20201938 |
| PubMedID: 34550207 |
| Title : Oxidative stress responses after exposure to triclosan sublethal concentrations: an integrated biomarker approach with a native (Corydoras paleatus) and a model fish species (Danio rerio) - Sager_2021_J.Toxicol.Environ.Health.A__1 |
| Author(s) : Sager E , Scarcia P , Marino D , Mac Loughlin T , Rossi A , de La Torre F |
| Ref : J Toxicol Environ Health A , :1 , 2021 |
| Abstract : |
| PubMedSearch : Sager_2021_J.Toxicol.Environ.Health.A__1 |
| PubMedID: 34879786 |
| Title : Multibiomarker responses in Danio rerio after exposure to sediment spiked with triclosan - Sager_2021_An.Acad.Bras.Cienc_93_e20201938 |
| Author(s) : Sager E , Rossi A , Loughlin TM , Marino D , Torre F |
| Ref : An Acad Bras Cienc , 93 :e20201938 , 2021 |
| Abstract : |
| PubMedSearch : Sager_2021_An.Acad.Bras.Cienc_93_e20201938 |
| PubMedID: 34550207 |
| Title : Oxidative stress responses after exposure to triclosan sublethal concentrations: an integrated biomarker approach with a native (Corydoras paleatus) and a model fish species (Danio rerio) - Sager_2021_J.Toxicol.Environ.Health.A__1 |
| Author(s) : Sager E , Scarcia P , Marino D , Mac Loughlin T , Rossi A , de La Torre F |
| Ref : J Toxicol Environ Health A , :1 , 2021 |
| Abstract : |
| PubMedSearch : Sager_2021_J.Toxicol.Environ.Health.A__1 |
| PubMedID: 34879786 |
| Title : Multibiomarker responses in Danio rerio after exposure to sediment spiked with triclosan - Sager_2021_An.Acad.Bras.Cienc_93_e20201938 |
| Author(s) : Sager E , Rossi A , Loughlin TM , Marino D , Torre F |
| Ref : An Acad Bras Cienc , 93 :e20201938 , 2021 |
| Abstract : |
| PubMedSearch : Sager_2021_An.Acad.Bras.Cienc_93_e20201938 |
| PubMedID: 34550207 |
| Title : Oxidative stress responses after exposure to triclosan sublethal concentrations: an integrated biomarker approach with a native (Corydoras paleatus) and a model fish species (Danio rerio) - Sager_2021_J.Toxicol.Environ.Health.A__1 |
| Author(s) : Sager E , Scarcia P , Marino D , Mac Loughlin T , Rossi A , de La Torre F |
| Ref : J Toxicol Environ Health A , :1 , 2021 |
| Abstract : |
| PubMedSearch : Sager_2021_J.Toxicol.Environ.Health.A__1 |
| PubMedID: 34879786 |
| Title : SMN-primed ribosomes modulate the translation of transcripts related to spinal muscular atrophy - Lauria_2020_Nat.Cell.Biol_22_1239 |
| Author(s) : Lauria F , Bernabo P , Tebaldi T , Groen EJN , Perenthaler E , Maniscalco F , Rossi A , Donzel D , Clamer M , Marchioretto M , Omersa N , Orri J , Dalla Serra M , Anderluh G , Quattrone A , Inga A , Gillingwater TH , Viero G |
| Ref : Nat Cell Biol , 22 :1239 , 2020 |
| Abstract : |
| PubMedSearch : Lauria_2020_Nat.Cell.Biol_22_1239 |
| PubMedID: 32958857 |
| Title : SMN-primed ribosomes modulate the translation of transcripts related to spinal muscular atrophy - Lauria_2020_Nat.Cell.Biol_22_1239 |
| Author(s) : Lauria F , Bernabo P , Tebaldi T , Groen EJN , Perenthaler E , Maniscalco F , Rossi A , Donzel D , Clamer M , Marchioretto M , Omersa N , Orri J , Dalla Serra M , Anderluh G , Quattrone A , Inga A , Gillingwater TH , Viero G |
| Ref : Nat Cell Biol , 22 :1239 , 2020 |
| Abstract : |
| PubMedSearch : Lauria_2020_Nat.Cell.Biol_22_1239 |
| PubMedID: 32958857 |
| Title : SMN-primed ribosomes modulate the translation of transcripts related to spinal muscular atrophy - Lauria_2020_Nat.Cell.Biol_22_1239 |
| Author(s) : Lauria F , Bernabo P , Tebaldi T , Groen EJN , Perenthaler E , Maniscalco F , Rossi A , Donzel D , Clamer M , Marchioretto M , Omersa N , Orri J , Dalla Serra M , Anderluh G , Quattrone A , Inga A , Gillingwater TH , Viero G |
| Ref : Nat Cell Biol , 22 :1239 , 2020 |
| Abstract : |
| PubMedSearch : Lauria_2020_Nat.Cell.Biol_22_1239 |
| PubMedID: 32958857 |
| Title : Pharmacological profile and efficiency in vivo of diflapolin, the first dual inhibitor of 5-lipoxygenase-activating protein and soluble epoxide hydrolase - Garscha_2017_Sci.Rep_7_9398 |
| Author(s) : Garscha U , Romp E , Pace S , Rossi A , Temml V , Schuster D , Konig S , Gerstmeier J , Liening S , Werner M , Atze H , Wittmann S , Weinigel C , Rummler S , Scriba GK , Sautebin L , Werz O |
| Ref : Sci Rep , 7 :9398 , 2017 |
| Abstract : |
| PubMedSearch : Garscha_2017_Sci.Rep_7_9398 |
| PubMedID: 28839250 |
| Title : Pharmacological profile and efficiency in vivo of diflapolin, the first dual inhibitor of 5-lipoxygenase-activating protein and soluble epoxide hydrolase - Garscha_2017_Sci.Rep_7_9398 |
| Author(s) : Garscha U , Romp E , Pace S , Rossi A , Temml V , Schuster D , Konig S , Gerstmeier J , Liening S , Werner M , Atze H , Wittmann S , Weinigel C , Rummler S , Scriba GK , Sautebin L , Werz O |
| Ref : Sci Rep , 7 :9398 , 2017 |
| Abstract : |
| PubMedSearch : Garscha_2017_Sci.Rep_7_9398 |
| PubMedID: 28839250 |
| Title : Pharmacological profile and efficiency in vivo of diflapolin, the first dual inhibitor of 5-lipoxygenase-activating protein and soluble epoxide hydrolase - Garscha_2017_Sci.Rep_7_9398 |
| Author(s) : Garscha U , Romp E , Pace S , Rossi A , Temml V , Schuster D , Konig S , Gerstmeier J , Liening S , Werner M , Atze H , Wittmann S , Weinigel C , Rummler S , Scriba GK , Sautebin L , Werz O |
| Ref : Sci Rep , 7 :9398 , 2017 |
| Abstract : |
| PubMedSearch : Garscha_2017_Sci.Rep_7_9398 |
| PubMedID: 28839250 |
| Title : Poster: alpha5 nAChR modulation of the effects of nicotine on ventral-striatal DA release and cue-reward learning - |
| Author(s) : Howe W , Tierney PL , Rossi A , Young D , Guillmette E , Kozak R |
| Ref : Biochemical Pharmacology , 97 :634 , 2015 |
| PubMedID: |
| Title : Poster: alpha5 nAChR modulation of the effects of nicotine on ventral-striatal DA release and cue-reward learning - |
| Author(s) : Howe W , Tierney PL , Rossi A , Young D , Guillmette E , Kozak R |
| Ref : Biochemical Pharmacology , 97 :634 , 2015 |
| PubMedID: |
| Title : Poster: alpha5 nAChR modulation of the effects of nicotine on ventral-striatal DA release and cue-reward learning - |
| Author(s) : Howe W , Tierney PL , Rossi A , Young D , Guillmette E , Kozak R |
| Ref : Biochemical Pharmacology , 97 :634 , 2015 |
| PubMedID: |
| Title : A single amino acid substitution in one of the lipases of Aspergillus nidulans confers resistance to the antimycotic drug undecanoic acid - Brito-Madurro_2008_Biochem.Genet_46_557 |
| Author(s) : Brito-Madurro AG , Prade RA , Madurro JM , Santos MA , Peres NT , Cursino-Santos JR , Martinez-Rossi NM , Rossi A |
| Ref : Biochemical Genetics , 46 :557 , 2008 |
| Abstract : |
| PubMedSearch : Brito-Madurro_2008_Biochem.Genet_46_557 |
| PubMedID: 18516670 |
| Title : A single amino acid substitution in one of the lipases of Aspergillus nidulans confers resistance to the antimycotic drug undecanoic acid - Brito-Madurro_2008_Biochem.Genet_46_557 |
| Author(s) : Brito-Madurro AG , Prade RA , Madurro JM , Santos MA , Peres NT , Cursino-Santos JR , Martinez-Rossi NM , Rossi A |
| Ref : Biochemical Genetics , 46 :557 , 2008 |
| Abstract : |
| PubMedSearch : Brito-Madurro_2008_Biochem.Genet_46_557 |
| PubMedID: 18516670 |
| Title : A single amino acid substitution in one of the lipases of Aspergillus nidulans confers resistance to the antimycotic drug undecanoic acid - Brito-Madurro_2008_Biochem.Genet_46_557 |
| Author(s) : Brito-Madurro AG , Prade RA , Madurro JM , Santos MA , Peres NT , Cursino-Santos JR , Martinez-Rossi NM , Rossi A |
| Ref : Biochemical Genetics , 46 :557 , 2008 |
| Abstract : |
| PubMedSearch : Brito-Madurro_2008_Biochem.Genet_46_557 |
| PubMedID: 18516670 |
| Title : Neurotoxic effects of 2,5-hexanedione in rats: early morphological and functional changes in nerve fibres and neuromuscular junctions - Cangiano_1981_Neurotoxicol_2_25 |
| Author(s) : Cangiano A , Lutzemberger L , Rizzuto N , Simonati A , Rossi A , Toschi G |
| Ref : Neurotoxicology , 2 :25 , 1981 |
| Abstract : |
| PubMedSearch : Cangiano_1981_Neurotoxicol_2_25 |
| PubMedID: 15622721 |
| Title : Neurotoxic effects of 2,5-hexanedione in rats: early morphological and functional changes in nerve fibres and neuromuscular junctions - Cangiano_1981_Neurotoxicol_2_25 |
| Author(s) : Cangiano A , Lutzemberger L , Rizzuto N , Simonati A , Rossi A , Toschi G |
| Ref : Neurotoxicology , 2 :25 , 1981 |
| Abstract : |
| PubMedSearch : Cangiano_1981_Neurotoxicol_2_25 |
| PubMedID: 15622721 |
| Title : Neurotoxic effects of 2,5-hexanedione in rats: early morphological and functional changes in nerve fibres and neuromuscular junctions - Cangiano_1981_Neurotoxicol_2_25 |
| Author(s) : Cangiano A , Lutzemberger L , Rizzuto N , Simonati A , Rossi A , Toschi G |
| Ref : Neurotoxicology , 2 :25 , 1981 |
| Abstract : |
| PubMedSearch : Cangiano_1981_Neurotoxicol_2_25 |
| PubMedID: 15622721 |
| Title : Acetylcholine receptors in the ciliary ganglion and in the iris muscle of the chick: specific binding and effect on the synaptic transmission of the neurotoxin from Naja naja siamensis - Conti-Tronconi_1979_Br.J.Pharmacol_66_33 |
| Author(s) : Conti-Tronconi B , Gotti C , Paggi P , Rossi A |
| Ref : British Journal of Pharmacology , 66 :33 , 1979 |
| Abstract : |
| PubMedSearch : Conti-Tronconi_1979_Br.J.Pharmacol_66_33 |
| PubMedID: 222384 |
| Title : Acetylcholine receptors in the ciliary ganglion and in the iris muscle of the chick: specific binding and effect on the synaptic transmission of the neurotoxin from Naja naja siamensis - Conti-Tronconi_1979_Br.J.Pharmacol_66_33 |
| Author(s) : Conti-Tronconi B , Gotti C , Paggi P , Rossi A |
| Ref : British Journal of Pharmacology , 66 :33 , 1979 |
| Abstract : |
| PubMedSearch : Conti-Tronconi_1979_Br.J.Pharmacol_66_33 |
| PubMedID: 222384 |
| Title : Acetylcholine receptors in the ciliary ganglion and in the iris muscle of the chick: specific binding and effect on the synaptic transmission of the neurotoxin from Naja naja siamensis - Conti-Tronconi_1979_Br.J.Pharmacol_66_33 |
| Author(s) : Conti-Tronconi B , Gotti C , Paggi P , Rossi A |
| Ref : British Journal of Pharmacology , 66 :33 , 1979 |
| Abstract : |
| PubMedSearch : Conti-Tronconi_1979_Br.J.Pharmacol_66_33 |
| PubMedID: 222384 |