Manfra M

Title : Furazanopyrazine-based novel promising anticancer agents interfering with the eicosanoid biosynthesis pathways by dual mPGES-1 and sEH inhibition - Lauro_2025_Eur.J.Med.Chem_289_117402

Author(s) : Lauro G , Aliberti M , De Nisco M , Pedatella S , Pepe G , Basilicata MG , Chini MG , Fischer K , Hofstetter RK , Werz O , Ferraro MG , Piccolo M , Irace C , Saviano A , Campiglia P , Bertamino A , Ostacolo C , Ciaglia T , Manfra M , Bifulco G

Ref : Eur Journal of Medicinal Chemistry , 289 :117402 , 2025

Abstract :

PubMedSearch : Lauro_2025_Eur.J.Med.Chem_289_117402

PubMedID: 40010271

Title : An adamantylureido-benzylamide aniline as FLAP\/sEH dual inhibitor: Rational design, in vitro and in vivo lipidomic profiling - Ciaglia_2025_Eur.J.Med.Chem_302_118338

Author(s) : Ciaglia T , D'Avino D , Jordan PM , Di Micco S , Musella S , Engelbrecht H , Peltner LK , Di Sarno V , Merciai F , Perna S , Smaldone G , Di Matteo F , Napolitano V , Stimoli R , Bifulco G , Pepe G , Sommella EM , Basilicata MG , Aquino G , Gomez-Monterrey IM , Campiglia P , Ostacolo C , Werz O , Rossi A , Bertamino A , Manfra M

Ref : Eur Journal of Medicinal Chemistry , 302 :118338 , 2025

Abstract :

PubMedSearch : Ciaglia_2025_Eur.J.Med.Chem_302_118338

PubMedID: 41197472

Gene_locus related to this paper: human-EPHX2

Manfra M

References (2)

1. Furazanopyrazine-based novel promising anticancer agents interfering with the eicosanoid biosynthesis pathways by dual mPGES-1 and sEH inhibition - Lauro_2025_Eur.J.Med.Chem_289_117402

2. An adamantylureido-benzylamide aniline as FLAP\/sEH dual inhibitor: Rational design, in vitro and in vivo lipidomic profiling - Ciaglia_2025_Eur.J.Med.Chem_302_118338