| Title : Potent soluble epoxide hydrolase inhibitors based on thiazole-5-carboxamide structure with imidazolidinone moiety as a secondary pharmacophore - Lengerli_2025_Bioorg.Chem_163_108644 |
| Author(s) : Lengerli D , Koc B , Jordan PM , Caliskan K , Caliskan B , Werz O , Banoglu E |
| Ref : Bioorg Chem , 163 :108644 , 2025 |
| Abstract : |
| PubMedSearch : Lengerli_2025_Bioorg.Chem_163_108644 |
| PubMedID: 40466300 |
| Title : Phenyl-benzyl-ureas with pyridazinone motif: Potent soluble epoxide hydrolase inhibitors with enhanced pharmacokinetics and efficacy in a paclitaxel-induced neuropathic pain model - Lengerli_2025_Eur.J.Med.Chem_290_117510 |
| Author(s) : Lengerli D , Bakht A , Caliskan K , Dahlke P , Bal NB , Jordan PM , Caliskan B , Werz O , Banoglu E |
| Ref : Eur Journal of Medicinal Chemistry , 290 :117510 , 2025 |
| Abstract : |
| PubMedSearch : Lengerli_2025_Eur.J.Med.Chem_290_117510 |
| PubMedID: 40101448 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : Harnessing structure-activity relationships to repurpose the FLAP inhibitor BRP-7 into potent and selective sEH inhibitors - Caliskan_2025_Bioorg.Chem_165_108997 |
| Author(s) : Caliskan K , Karatas M , Jordan PM , Caliskan B , Werz O , Banoglu E |
| Ref : Bioorg Chem , 165 :108997 , 2025 |
| Abstract : |
| PubMedSearch : Caliskan_2025_Bioorg.Chem_165_108997 |
| PubMedID: 40974655 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : An adamantylureido-benzylamide aniline as FLAP\/sEH dual inhibitor: Rational design, in vitro and in vivo lipidomic profiling - Ciaglia_2025_Eur.J.Med.Chem_302_118338 |
| Author(s) : Ciaglia T , D'Avino D , Jordan PM , Di Micco S , Musella S , Engelbrecht H , Peltner LK , Di Sarno V , Merciai F , Perna S , Smaldone G , Di Matteo F , Napolitano V , Stimoli R , Bifulco G , Pepe G , Sommella EM , Basilicata MG , Aquino G , Gomez-Monterrey IM , Campiglia P , Ostacolo C , Werz O , Rossi A , Bertamino A , Manfra M |
| Ref : Eur Journal of Medicinal Chemistry , 302 :118338 , 2025 |
| Abstract : |
| PubMedSearch : Ciaglia_2025_Eur.J.Med.Chem_302_118338 |
| PubMedID: 41197472 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : Benzoxazolone-5-Urea Derivatives as Human Soluble Epoxide Hydrolase (sEH) Inhibitors - Gur_2023_ACS.Omega_8_2445 |
| Author(s) : Gur Maz T , Koc B , Jordan PM , Ibis K , Caliskan B , Werz O , Banoglu E |
| Ref : ACS Omega , 8 :2445 , 2023 |
| Abstract : |
| PubMedSearch : Gur_2023_ACS.Omega_8_2445 |
| PubMedID: 36687110 |
| Title : Discovery and optimization of piperazine urea derivatives as soluble epoxide hydrolase (sEH) inhibitors - Capan_2022_ChemMedChem__ |
| Author(s) : Capan I , Jordan PM , Olgac A , Caliskan B , Kretzer C , Werz O , Banoglu E |
| Ref : ChemMedChem , : , 2022 |
| Abstract : |
| PubMedSearch : Capan_2022_ChemMedChem__ |
| PubMedID: 35466565 |
| Title : Quinazoline-4(3H)-one-7-carboxamide Derivatives as Human Soluble Epoxide Hydrolase Inhibitors with Developable 5-Lipoxygenase Activating Protein Inhibition - Turanli_2022_ACS.Omega_7_36354 |
| Author(s) : Turanli S , Ergul AG , Jordan PM , Olgac A , Caliskan B , Werz O , Banoglu E |
| Ref : ACS Omega , 7 :36354 , 2022 |
| Abstract : |
| PubMedSearch : Turanli_2022_ACS.Omega_7_36354 |
| PubMedID: 36278102 |