Perna S

Title : Identification of a New, Potent, and Stable Tetrahydroquinoline-Based 5-LOX\/sEH Dual Inhibitor with Polymodal Anti-Inflammatory Activity in Acute Pancreatitis - D'Avino_2026_J.Med.Chem__

Author(s) : D'Avino D , Ciaglia T , Jordan PM , Di Micco S , Musella S , Di Sarno V , Merciai F , Perna S , Smaldone G , Di Matteo F , Napolitano V , Stimoli R , Sardo I , Ricci O , Bifulco G , Sommella EM , Basilicata MG , Ferrara G , Roviezzo F , Di Dio A , Aquino G , Pellecchia S , Pepe G , Gomez-Monterrey IM , Campiglia P , Ostacolo C , Manfra M , Werz O , Rossi A , Bertamino A

Ref : Journal of Medicinal Chemistry , : , 2026

Abstract :

PubMedSearch : D'Avino_2026_J.Med.Chem__

PubMedID: 42504850

Gene_locus related to this paper: human-EPHX2

Title : An adamantylureido-benzylamide aniline as FLAP\/sEH dual inhibitor: Rational design, in vitro and in vivo lipidomic profiling - Ciaglia_2025_Eur.J.Med.Chem_302_118338

Author(s) : Ciaglia T , D'Avino D , Jordan PM , Di Micco S , Musella S , Engelbrecht H , Peltner LK , Di Sarno V , Merciai F , Perna S , Smaldone G , Di Matteo F , Napolitano V , Stimoli R , Bifulco G , Pepe G , Sommella EM , Basilicata MG , Aquino G , Gomez-Monterrey IM , Campiglia P , Ostacolo C , Werz O , Rossi A , Bertamino A , Manfra M

Ref : Eur Journal of Medicinal Chemistry , 302 :118338 , 2025

Abstract :

PubMedSearch : Ciaglia_2025_Eur.J.Med.Chem_302_118338

PubMedID: 41197472

Gene_locus related to this paper: human-EPHX2

Perna S

References (2)

1. Identification of a New, Potent, and Stable Tetrahydroquinoline-Based 5-LOX\/sEH Dual Inhibitor with Polymodal Anti-Inflammatory Activity in Acute Pancreatitis - D'Avino_2026_J.Med.Chem__

2. An adamantylureido-benzylamide aniline as FLAP\/sEH dual inhibitor: Rational design, in vitro and in vivo lipidomic profiling - Ciaglia_2025_Eur.J.Med.Chem_302_118338