| Title : Novel Dual-Acting Hybrids Targeting Type-2 Cannabinoid Receptors and Cholinesterase Activity Show Neuroprotective Effects In Vitro and Amelioration of Cognitive Impairment In Vivo - Mugnaini_2024_ACS.Chem.Neurosci__ |
| Author(s) : Mugnaini C , Brizzi A , Paolino M , Scarselli E , Castelli R , de Candia M , Gambacorta N , Nicolotti O , Kostrzewa M , Kumar P , Mahmoud AM , Borgonetti V , Iannotta M , Morace A , Galeotti N , Maione S , Altomare CD , Ligresti A , Corelli F |
| Ref : ACS Chem Neurosci , : , 2024 |
| Abstract : |
| PubMedSearch : Mugnaini_2024_ACS.Chem.Neurosci__ |
| PubMedID: 38372253 |
| Title : Assessing the Role of a Malonamide Linker in the Design of Potent Dual Inhibitors of Factor Xa and Cholinesterases - Purgatorio_2022_Molecules_27_ |
| Author(s) : Purgatorio R , Gambacorta N , Samarelli F , Lopopolo G , de Candia M , Catto M , Nicolotti O , Altomare CD |
| Ref : Molecules , 27 : , 2022 |
| Abstract : |
| PubMedSearch : Purgatorio_2022_Molecules_27_ |
| PubMedID: 35807514 |
| Title : Morpholine-based chalcones as dual-acting monoamine oxidase-B and acetylcholinesterase inhibitors: synthesis and biochemical investigations - Sasidharan_2021_J.Enzyme.Inhib.Med.Chem_36_188 |
| Author(s) : Sasidharan R , Eom BH , Heo JH , Park JE , Abdelgawad MA , Musa A , Gambacorta N , Nicolotti O , Manju SL , Mathew B , Kim H |
| Ref : J Enzyme Inhib Med Chem , 36 :188 , 2021 |
| Abstract : |
| PubMedSearch : Sasidharan_2021_J.Enzyme.Inhib.Med.Chem_36_188 |
| PubMedID: 33430657 |
| Title : Halogenated Coumarin-Chalcones as Multifunctional Monoamine Oxidase-B and Butyrylcholinesterase Inhibitors - Rehuman_2021_ACS.Omega_6_28182 |
| Author(s) : Rehuman NA , Oh JM , Nath LR , Khames A , Abdelgawad MA , Gambacorta N , Nicolotti O , Jat RK , Kim H , Mathew B |
| Ref : ACS Omega , 6 :28182 , 2021 |
| Abstract : |
| PubMedSearch : Rehuman_2021_ACS.Omega_6_28182 |
| PubMedID: 34723016 |
| Title : Away from Flatness: Unprecedented Nitrogen-Bridged Cyclopenta[a]indene Derivatives as Novel Anti-Alzheimer Multitarget Agents - Titov_2021_ACS.Chem.Neurosci__ |
| Author(s) : Titov AA , Kobzev MS , Catto M , de Candia M , Gambacorta N , Denora N , Pisani L , Nicolotti O , Borisova TN , Varlamov AV , Voskressensky LG , Altomare CD |
| Ref : ACS Chem Neurosci , : , 2021 |
| Abstract : |
| PubMedSearch : Titov_2021_ACS.Chem.Neurosci__ |
| PubMedID: 33395258 |
| Title : Piperazine-substituted chalcones: a new class of MAO-B, AChE, and BACE-1 inhibitors for the treatment of neurological disorders - Mathew_2021_Environ.Sci.Pollut.Res.Int__1 |
| Author(s) : Mathew B , Oh JM , Baty RS , Batiha GE , Parambi DGT , Gambacorta N , Nicolotti O , Kim H |
| Ref : Environ Sci Pollut Res Int , :1 , 2021 |
| Abstract : |
| PubMedSearch : Mathew_2021_Environ.Sci.Pollut.Res.Int__1 |
| PubMedID: 33743158 |
| Title : First-in-Class Isonipecotamide-Based Thrombin and Cholinesterase Dual Inhibitors with Potential for Alzheimer Disease - Purgatorio_2021_Molecules_26_ |
| Author(s) : Purgatorio R , Gambacorta N , de Candia M , Catto M , Rullo M , Pisani L , Nicolotti O , Altomare CD |
| Ref : Molecules , 26 : , 2021 |
| Abstract : |
| PubMedSearch : Purgatorio_2021_Molecules_26_ |
| PubMedID: 34500640 |
| Title : Novel Class of Chalcone Oxime Ethers as Potent Monoamine Oxidase-B and Acetylcholinesterase Inhibitors - Oh_2020_Molecules_25_ |
| Author(s) : Oh JM , Rangarajan TM , Chaudhary R , Singh RP , Singh M , Tondo AR , Gambacorta N , Nicolotti O , Mathew B , Kim H |
| Ref : Molecules , 25 : , 2020 |
| Abstract : |
| PubMedSearch : Oh_2020_Molecules_25_ |
| PubMedID: 32443652 |
| Title : Selected 1,3-Benzodioxine-Containing Chalcones as Multipotent Oxidase and Acetylcholinesterase Inhibitors - Jeong_2020_ChemMedChem_15_2257 |
| Author(s) : Jeong GS , Kaipakasseri S , Lee SR , Marraiki N , Batiha GE , Dev S , Palakkathondi A , Kavully FS , Gambacorta N , Nicolotti O , Mathew B , Kim H |
| Ref : ChemMedChem , 15 :2257 , 2020 |
| Abstract : |
| PubMedSearch : Jeong_2020_ChemMedChem_15_2257 |
| PubMedID: 32924264 |
| Title : De novo drug design of targeted chemical libraries based on artificial intelligence and pair based multi-objective optimization - Alberga_2020_J.Chem.Inf.Model_60_4582 |
| Author(s) : Alberga D , Gambacorta N , Trisciuzzi D , Ciriaco F , Amoroso N , Nicolotti O |
| Ref : J Chem Inf Model , 60 :4582 , 2020 |
| Abstract : |
| PubMedSearch : Alberga_2020_J.Chem.Inf.Model_60_4582 |
| PubMedID: 32845150 |
| Title : (Hetero-)(arylidene)arylhydrazides as Multitarget-Directed Monoamine Oxidase Inhibitors - Palakkathondi_2020_ACS.Comb.Sci_22_592 |
| Author(s) : Palakkathondi A , Oh JM , Dev S , Rangarajan TM , Kaipakasseri S , Kavully FS , Gambacorta N , Nicolotti O , Kim H , Mathew B |
| Ref : ACS Comb Sci , 22 :592 , 2020 |
| Abstract : |
| PubMedSearch : Palakkathondi_2020_ACS.Comb.Sci_22_592 |
| PubMedID: 33047950 |