| Title : Novel 6-alkyl-bridged 4-arylalkylpiperazin-1-yl derivatives of azepino[4,3-b]indol-1(2H)-one as potent BChE-selective inhibitors showing protective effects against neurodegenerative insults - Samarelli_2024_Eur.J.Med.Chem_270_116353 |
| Author(s) : Samarelli F , Purgatorio R , Lopopolo G , Deruvo C , Catto M , Andresini M , Carrieri A , Nicolotti O , De Palma A , Miniero DV , de Candia M , Altomare CD |
| Ref : Eur Journal of Medicinal Chemistry , 270 :116353 , 2024 |
| Abstract : Samarelli_2024_Eur.J.Med.Chem_270_116353 |
| ESTHER : Samarelli_2024_Eur.J.Med.Chem_270_116353 |
| PubMedSearch : Samarelli_2024_Eur.J.Med.Chem_270_116353 |
| PubMedID: 38579622 |
| Title : Chemical and Biological Evaluation of Novel 1H-Chromeno[3,2-c]pyridine Derivatives as MAO Inhibitors Endowed with Potential Anticancer Activity - Kulikova_2023_Int.J.Mol.Sci_24_ |
| Author(s) : Kulikova LN , Purgatorio R , Beloglazkin AA , Tafeenko VA , Reza RG , Levickaya DD , Sblano S , Boccarelli A , de Candia M , Catto M , Voskressensky LG , Altomare CD |
| Ref : Int J Mol Sci , 24 : , 2023 |
| Abstract : Kulikova_2023_Int.J.Mol.Sci_24_ |
| ESTHER : Kulikova_2023_Int.J.Mol.Sci_24_ |
| PubMedSearch : Kulikova_2023_Int.J.Mol.Sci_24_ |
| PubMedID: 37175433 |
| Title : Investigation on Novel E\/Z 2-Benzylideneindan-1-One-Based Photoswitches with AChE and MAO-B Dual Inhibitory Activity - Paolino_2023_Molecules_28_ |
| Author(s) : Paolino M , de Candia M , Purgatorio R , Catto M , Saletti M , Tondo AR , Nicolotti O , Cappelli A , Brizzi A , Mugnaini C , Corelli F , Altomare CD |
| Ref : Molecules , 28 : , 2023 |
| Abstract : Paolino_2023_Molecules_28_ |
| ESTHER : Paolino_2023_Molecules_28_ |
| PubMedSearch : Paolino_2023_Molecules_28_ |
| PubMedID: 37570828 |
| Title : Novel thienocycloalkylpyridazinones as useful scaffolds for acetylcholinesterase inhibition and serotonin 5-HT(6) receptor interaction - Asproni_2023_Bioorg.Med.Chem_84_117256 |
| Author(s) : Asproni B , Catto M , Loriga G , Murineddu G , Corona P , Purgatorio R , Cichero E , Fossa P , Scarano N , Martinez AL , Brea J , Pinna GA |
| Ref : Bioorganic & Medicinal Chemistry , 84 :117256 , 2023 |
| Abstract : Asproni_2023_Bioorg.Med.Chem_84_117256 |
| ESTHER : Asproni_2023_Bioorg.Med.Chem_84_117256 |
| PubMedSearch : Asproni_2023_Bioorg.Med.Chem_84_117256 |
| PubMedID: 37003157 |
| Title : In-vitro and in-silico studies of annelated 1,4,7,8-tetrahydroazocine ester derivatives as nanomolar selective inhibitors of human butyrylcholinesterase - de Candia_2023_Chem.Biol.Interact_14ChEPon_110741 |
| Author(s) : de Candia M , Titov AA , Viayna A , Kulikova LN , Purgatorio R , Piergiovanni B , Niso M , Catto M , Voskressensky LG , Luque FJ , Altomare CD |
| Ref : Chemico-Biological Interactions , :110741 , 2023 |
| Abstract : de Candia_2023_Chem.Biol.Interact_14ChEPon_110741 |
| ESTHER : de Candia_2023_Chem.Biol.Interact_14ChEPon_110741 |
| PubMedSearch : de Candia_2023_Chem.Biol.Interact_14ChEPon_110741 |
| PubMedID: 37839515 |
| Title : Synthesis of Isomeric 3-Benzazecines Decorated with Endocyclic Allene Moiety and Exocyclic Conjugated Double Bond and Evaluation of Their Anticholinesterase Activity - Titov_2022_Molecules_27_ |
| Author(s) : Titov AA , Purgatorio R , Obydennik AY , Listratova AV , Borisova TN , de Candia M , Catto M , Altomare CD , Varlamov AV , Voskressensky LG |
| Ref : Molecules , 27 : , 2022 |
| Abstract : Titov_2022_Molecules_27_ |
| ESTHER : Titov_2022_Molecules_27_ |
| PubMedSearch : Titov_2022_Molecules_27_ |
| PubMedID: 36234811 |
| Title : Assessing the Role of a Malonamide Linker in the Design of Potent Dual Inhibitors of Factor Xa and Cholinesterases - Purgatorio_2022_Molecules_27_ |
| Author(s) : Purgatorio R , Gambacorta N , Samarelli F , Lopopolo G , de Candia M , Catto M , Nicolotti O , Altomare CD |
| Ref : Molecules , 27 : , 2022 |
| Abstract : Purgatorio_2022_Molecules_27_ |
| ESTHER : Purgatorio_2022_Molecules_27_ |
| PubMedSearch : Purgatorio_2022_Molecules_27_ |
| PubMedID: 35807514 |
| Title : Homobivalent Lamellarin-Like Schiff Bases: In Vitro Evaluation of Their Cancer Cell Cytotoxicity and Multitargeting Anti-Alzheimer's Disease Potential - Nevskaya_2021_Molecules_26_ |
| Author(s) : Nevskaya AA , Anikina LV , Purgatorio R , Catto M , Nicolotti O , de Candia M , Pisani L , Borisova TN , Miftyakhova AR , Varlamov AV , Nevskaya EY , Borisov RS , Voskressensky LG , Altomare CD |
| Ref : Molecules , 26 : , 2021 |
| Abstract : Nevskaya_2021_Molecules_26_ |
| ESTHER : Nevskaya_2021_Molecules_26_ |
| PubMedSearch : Nevskaya_2021_Molecules_26_ |
| PubMedID: 33445600 |
| Title : Evaluation of water-soluble Mannich base prodrugs of 2,3,4,5-tetrahydroazepino[4,3-b]indol-1(6H)-one as multitarget-directed agents for Alzheimer's disease - Purgatorio_2021_ChemMedChem_16_589 |
| Author(s) : Purgatorio R , de Candia M , Catto M , Rullo M , Pisani L , Denora N , Carrieri A , Nevskaya AA , Voskressensky LG , Altomare CD |
| Ref : ChemMedChem , 16 :589 , 2021 |
| Abstract : Purgatorio_2021_ChemMedChem_16_589 |
| ESTHER : Purgatorio_2021_ChemMedChem_16_589 |
| PubMedSearch : Purgatorio_2021_ChemMedChem_16_589 |
| PubMedID: 33156950 |
| Title : Synthesis of 8-phenyl substituted 3-benzazecines with allene moiety, their thermal rearrangement and evaluation as acetylcholinesterase inhibitors - Kobzev_2021_Mol.Divers__ |
| Author(s) : Kobzev MS , Titov AA , Alexandrova EV , Purgatorio R , Catto M , Sorokina EA , Borisova TN , Varlamov AV , Altomare CD , Voskressensky LG |
| Ref : Mol Divers , : , 2021 |
| Abstract : Kobzev_2021_Mol.Divers__ |
| ESTHER : Kobzev_2021_Mol.Divers__ |
| PubMedSearch : Kobzev_2021_Mol.Divers__ |
| PubMedID: 33538985 |
| Title : First-in-Class Isonipecotamide-Based Thrombin and Cholinesterase Dual Inhibitors with Potential for Alzheimer Disease - Purgatorio_2021_Molecules_26_ |
| Author(s) : Purgatorio R , Gambacorta N , de Candia M , Catto M , Rullo M , Pisani L , Nicolotti O , Altomare CD |
| Ref : Molecules , 26 : , 2021 |
| Abstract : Purgatorio_2021_Molecules_26_ |
| ESTHER : Purgatorio_2021_Molecules_26_ |
| PubMedSearch : Purgatorio_2021_Molecules_26_ |
| PubMedID: 34500640 |
| Title : Scouting around 1,2,3,4-Tetrahydrochromeno[3,2-c]pyridin-10-ones for Single- and Multi-target Ligands Directed towards Relevant Alzheimer's Targets - Purgatorio_2020_ChemMedChem_15_1947 |
| Author(s) : Purgatorio R , Kulikova L , Pisani L , Catto M , de Candia M , Carrieri A , Cellamare S , De Palma A , Beloglazkin A , Raesi GR , Voskressensky L , Altomare CD |
| Ref : ChemMedChem , 15 :1947 , 2020 |
| Abstract : Purgatorio_2020_ChemMedChem_15_1947 |
| ESTHER : Purgatorio_2020_ChemMedChem_15_1947 |
| PubMedSearch : Purgatorio_2020_ChemMedChem_15_1947 |
| PubMedID: 32716595 |
| Title : A Prospective Repurposing of Dantrolene as a Multitarget Agent for Alzheimer's Disease - Bolognino_2019_Molecules_24_ |
| Author(s) : Bolognino I , Giangregorio N , Pisani L , de Candia M , Purgatorio R , Tonazzi A , Altomare CD , Cellamare S , Catto M |
| Ref : Molecules , 24 : , 2019 |
| Abstract : Bolognino_2019_Molecules_24_ |
| ESTHER : Bolognino_2019_Molecules_24_ |
| PubMedSearch : Bolognino_2019_Molecules_24_ |
| PubMedID: 31775359 |
| Title : Investigating 1,2,3,4,5,6-hexahydroazepino[4,3-b]indole as scaffold of butyrylcholinesterase-selective inhibitors with additional neuroprotective activities for Alzheimer's disease - Purgatorio_2019_Eur.J.Med.Chem_177_414 |
| Author(s) : Purgatorio R , de Candia M , Catto M , Carrieri A , Pisani L , De Palma A , Toma M , Ivanova OA , Voskressensky LG , Altomare CD |
| Ref : Eur Journal of Medicinal Chemistry , 177 :414 , 2019 |
| Abstract : Purgatorio_2019_Eur.J.Med.Chem_177_414 |
| ESTHER : Purgatorio_2019_Eur.J.Med.Chem_177_414 |
| PubMedSearch : Purgatorio_2019_Eur.J.Med.Chem_177_414 |
| PubMedID: 31158754 |