| Title : Novel 6-alkyl-bridged 4-arylalkylpiperazin-1-yl derivatives of azepino[4,3-b]indol-1(2H)-one as potent BChE-selective inhibitors showing protective effects against neurodegenerative insults - Samarelli_2024_Eur.J.Med.Chem_270_116353 |
| Author(s) : Samarelli F , Purgatorio R , Lopopolo G , Deruvo C , Catto M , Andresini M , Carrieri A , Nicolotti O , De Palma A , Miniero DV , de Candia M , Altomare CD |
| Ref : Eur Journal of Medicinal Chemistry , 270 :116353 , 2024 |
| Abstract : |
| PubMedSearch : Samarelli_2024_Eur.J.Med.Chem_270_116353 |
| PubMedID: 38579622 |
| Title : Chiral pyrrolidines as multipotent agents in Alzheimer and neurodegenerative diseases - Carrieri_2024_Bioorg.Med.Chem_110_117829 |
| Author(s) : Carrieri A , Barbarossa A , de Candia M , Samarelli F , Damiano Altomare C , Czarnota-Lydka K , Sudol-Talaj S , Latacz G , Handzlik J , Brunetti L , Piemontese L , Limongelli F , Lentini G , Carocci A |
| Ref : Bioorganic & Medicinal Chemistry , 110 :117829 , 2024 |
| Abstract : |
| PubMedSearch : Carrieri_2024_Bioorg.Med.Chem_110_117829 |
| PubMedID: 39002183 |
| Title : Synthesis, computational and experimental pharmacological studies for (thio)ether-triazine 5-HT(6)R ligands with noticeable action on AChE\/BChE and chalcogen-dependent intrinsic activity in search for new class of drugs against Alzheimer's disease - Czarnota-Lydka_2023_Eur.J.Med.Chem_259_115695 |
| Author(s) : Czarnota-Lydka K , Sudol-Talaj S , Kucwaj-Brysz K , Kurczab R , Satala G , de Candia M , Samarelli F , Altomare CD , Carocci A , Barbarossa A , eslawska E , Gluch-Lutwin M , Mordyl B , Kubacka M , Wilczynska-Zawal N , Jastrzebska-Wiesek M , Partyka A , Khan N , Wiecek M , Nitek W , Honkisz-Orzechowska E , Latacz G , Wesolowska A , Carrieri A , Handzlik J |
| Ref : Eur Journal of Medicinal Chemistry , 259 :115695 , 2023 |
| Abstract : |
| PubMedSearch : Czarnota-Lydka_2023_Eur.J.Med.Chem_259_115695 |
| PubMedID: 37567058 |
| Title : Assessing the Role of a Malonamide Linker in the Design of Potent Dual Inhibitors of Factor Xa and Cholinesterases - Purgatorio_2022_Molecules_27_ |
| Author(s) : Purgatorio R , Gambacorta N , Samarelli F , Lopopolo G , de Candia M , Catto M , Nicolotti O , Altomare CD |
| Ref : Molecules , 27 : , 2022 |
| Abstract : |
| PubMedSearch : Purgatorio_2022_Molecules_27_ |
| PubMedID: 35807514 |