Title : Poster (46) Major hallmarks in alzheimer's disease (ad) can beneficially be modulated by M1 muscarinic agonists - an added value vs. cholinesterase inhibitors - |
Author(s) : Fisher A , Brandeis R , Pittel Z , Haring R , Sparks L , Beach TG , Bons N , Maestre-Frances N , Bar-Ner N , Kliger-Spatz M , Natan N , Marcovitch I , Hartmann T |
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :345 , 2004 |
PubMedID: |
Title : Beta-amyloids, tau hyperphosphorylation and cognition are beneficially affected by M1 muscarinic agonists. - |
Author(s) : Pittel Z , Haring R , Bons N , Bar-Ner N , Sonego H , Natan N , Marcovitch I , Brandeis R |
Ref : Cholinergic Mechanisms, CRC Press :345 , 2004 |
PubMedID: |
Title : M1 muscarinic agonists can modulate some of the hallmarks in Alzheimer's disease: implications in future therapy - Fisher_2003_J.Mol.Neurosci_20_349 |
Author(s) : Fisher A , Pittel Z , Haring R , Bar-Ner N , Kliger-Spatz M , Natan N , Egozi I , Sonego H , Marcovitch I , Brandeis R |
Ref : Journal of Molecular Neuroscience , 20 :349 , 2003 |
Abstract : |
PubMedSearch : Fisher_2003_J.Mol.Neurosci_20_349 |
PubMedID: 14501019 |
Title : M1 muscarinic agonists as potential disease-modifying agents in Alzheimer's disease. Rationale and perspectives - Fisher_2000_Ann.N.Y.Acad.Sci_920_315 |
Author(s) : Fisher A , Michaelson DM , Brandeis R , Haring R , Chapman S , Pittel Z |
Ref : Annals of the New York Academy of Sciences , 920 :315 , 2000 |
Abstract : |
PubMedSearch : Fisher_2000_Ann.N.Y.Acad.Sci_920_315 |
PubMedID: 11193170 |
Title : Novel m1 muscarinic agonists in treatment and delaying the progression of Alzheimer's disease: An unifying hypothesis - Fisher_1998_J.Physiol.Paris_92_337 |
Author(s) : Fisher A , Brandeis R , Haring R , Eshhar N , Heldman E , Karton Y , Eisenberg O , Meshulam H , Marciano D , Bar-Ner N , Pittel Z |
Ref : Journal de Physiologie (Paris) , 92 :337 , 1998 |
Abstract : |
PubMedSearch : Fisher_1998_J.Physiol.Paris_92_337 |
PubMedID: 9789833 |
Title : Muscarinic control of amyloid precursor protein secretion in rat cerebral cortex and cerebellum - Pittel_1996_Brain.Res_742_299 |
Author(s) : Pittel Z , Heldman E , Barg J , Haring R , Fisher A |
Ref : Brain Research , 742 :299 , 1996 |
Abstract : |
PubMedSearch : Pittel_1996_Brain.Res_742_299 |
PubMedID: 9117408 |
Title : Dehydroepiandrosterone (DHEA) increases production and release of Alzheimer's amyloid precursor protein - Danenberg_1996_Life.Sci_59_1651 |
Author(s) : Danenberg HD , Haring R , Fisher A , Pittel Z , Gurwitz D , Heldman E |
Ref : Life Sciences , 59 :1651 , 1996 |
Abstract : |
PubMedSearch : Danenberg_1996_Life.Sci_59_1651 |
PubMedID: 8913330 |
Title : M1 agonists for the treatment of Alzheimer's disease. Novel properties and clinical update - Fisher_1996_Ann.N.Y.Acad.Sci_777_189 |
Author(s) : Fisher A , Heldman E , Gurwitz D , Haring R , Karton Y , Meshulam H , Pittel Z , Marciano D , Brandeis R , Sadot E , Barg Y , Pinkas-Kramarski R , Vogel Z , Ginzburg I , Treves TA , Verchovsky R , Klimowsky S , Korczyn AD |
Ref : Annals of the New York Academy of Sciences , 777 :189 , 1996 |
Abstract : |
PubMedSearch : Fisher_1996_Ann.N.Y.Acad.Sci_777_189 |
PubMedID: 8624083 |
Title : Dehydroepiandrosterone augments M1-muscarinic receptor-stimulated amyloid precursor protein secretion in desensitized PC12M1 cells - Danenberg_1995_Ann.N.Y.Acad.Sci_774_300 |
Author(s) : Danenberg HD , Haring R , Heldman E , Gurwitz D , Ben-Nathan D , Pittel Z , Zuckerman A , Fisher A |
Ref : Annals of the New York Academy of Sciences , 774 :300 , 1995 |
Abstract : |
PubMedSearch : Danenberg_1995_Ann.N.Y.Acad.Sci_774_300 |
PubMedID: 8597471 |
Title : Discrete activation of transduction pathways associated with acetylcholine m1 receptor by several muscarinic ligands - Gurwitz_1994_Eur.J.Pharmacol_267_21 |
Author(s) : Gurwitz D , Haring R , Heldman E , Fraser CM , Manor D , Fisher A |
Ref : European Journal of Pharmacology , 267 :21 , 1994 |
Abstract : |
PubMedSearch : Gurwitz_1994_Eur.J.Pharmacol_267_21 |
PubMedID: 8206127 |
Title : Selective signaling via unique M1 muscarinic agonists - Fisher_1993_Ann.N.Y.Acad.Sci_695_300 |
Author(s) : Fisher A , Heldman E , Gurwitz D , Haring R , Barak D , Meshulam H , Marciano D , Brandeis R , Pittel Z , Segal M , et al. |
Ref : Annals of the New York Academy of Sciences , 695 :300 , 1993 |
Abstract : |
PubMedSearch : Fisher_1993_Ann.N.Y.Acad.Sci_695_300 |
PubMedID: 8239299 |
Title : Progress in medicinal chemistry of novel selective muscarinic agonists - Fisher_1993_Drug.Des.Discov_9_221 |
Author(s) : Fisher A , Karton Y , Heldman E , Gurwitz D , Haring R , Meshulam H , Brandeis R , Pittel Z , Segall Y , Marciano D , et al. |
Ref : Drug Des Discov , 9 :221 , 1993 |
Abstract : |
PubMedSearch : Fisher_1993_Drug.Des.Discov_9_221 |
PubMedID: 8400004 |
Title : (+-)-cis-2-methyl-spiro(1,3-oxathiolane-5,3')quinuclidine, an M1 selective cholinergic agonist, attenuates cognitive dysfunctions in an animal model of Alzheimer's disease - Fisher_1991_J.Pharmacol.Exp.Ther_257_392 |
Author(s) : Fisher A , Brandeis R , Karton I , Pittel Z , Gurwitz D , Haring R , Sapir M , Levy A , Heldman E |
Ref : Journal of Pharmacology & Experimental Therapeutics , 257 :392 , 1991 |
Abstract : |
PubMedSearch : Fisher_1991_J.Pharmacol.Exp.Ther_257_392 |
PubMedID: 2019998 |
Title : Localization of azidophencyclidine-binding site on the nicotinic acetylcholine receptor alpha-subunit - Mosckovitz_1987_Biochem.Biophys.Res.Commun_145_810 |
Author(s) : Mosckovitz R , Haring R , Gershoni JM , Kloog Y , Sokolovsky M |
Ref : Biochemical & Biophysical Research Communications , 145 :810 , 1987 |
Abstract : |
PubMedSearch : Mosckovitz_1987_Biochem.Biophys.Res.Commun_145_810 |
PubMedID: 3297059 |