Fisher A

General

Full name : Fisher Avraham

First name : Avraham

Mail : Weizmann Institute of Science. Neurobiology

Zip Code :

City :

Country : Israel

Email : fisher_a@netvision.net.il

Phone : 972 89381603

Fax : 972 89381615

Website :

Directory :

References (50)

Title : Reimagining cholinergic therapy for Alzheimer's disease - Giacobini_2022_Brain_145_2250
Author(s) : Giacobini E , Cuello AC , Fisher A
Ref : Brain , 145 :2250 , 2022
PubMedID: 35289363

Title : Policy-induced selection bias in pharmacoepidemiology: The example of coverage for Alzheimer's medications in British Columbia - Fisher_2019_Pharmacoepidemiol.Drug.Saf_28_1067
Author(s) : Fisher A , Carney G , Bassett K , Maclure KM , Dormuth CR
Ref : Pharmacoepidemiol Drug Safety , 28 :1067 , 2019
PubMedID: 31267629

Title : Tolerability of Cholinesterase Inhibitors: A Population-Based Study of Persistence, Adherence, and Switching - Fisher_2017_Drugs.Aging_34_221
Author(s) : Fisher A , Carney G , Bassett K , Dormuth CR
Ref : Drugs & Aging , 34 :221 , 2017
PubMedID: 28138912

Title : Cholinesterase Inhibitor Utilization: The Impact of Provincial Drug Policy on Discontinuation - Fisher_2016_Value.Health_19_688
Author(s) : Fisher A , Carney G , Bassett K , Chappell NL
Ref : Value Health , 19 :688 , 2016
PubMedID: 27565287

Title : Acute Effects of Muscarinic M1 Receptor Modulation on AbetaPP Metabolism and Amyloid-beta Levels in vivo: A Microdialysis Study - Welt_2015_J.Alzheimers.Dis_46_971
Author(s) : Welt T , Kulic L , Hoey SE , McAfoose J , Spani C , Chadha AS , Fisher A , Nitsch RM
Ref : J Alzheimers Dis , 46 :971 , 2015
PubMedID: 25881909

Title : Cholinergic modulation of amyloid precursor protein processing with emphasis on M1 muscarinic receptor: perspectives and challenges in treatment of Alzheimer's disease - Fisher_2012_J.Neurochem_120 Suppl 1_22
Author(s) : Fisher A
Ref : Journal of Neurochemistry , 120 Suppl 1 :22 , 2012
PubMedID: 22122190

Title : Isoform-specific contribution of protein kinase C to prion processing - Alfa_2008_Mol.Cell.Neurosci_39_400
Author(s) : Alfa Cisse M , Louis K , Braun U , Mari B , Leitges M , Slack BE , Fisher A , Auberger P , Checler F , Vincent B
Ref : Molecular & Cellular Neurosciences , 39 :400 , 2008
PubMedID: 18722532

Title : Cholinergic treatments with emphasis on m1 muscarinic agonists as potential disease-modifying agents for Alzheimer's disease - Fisher_2008_Neurotherapeutics_5_433
Author(s) : Fisher A
Ref : Neurotherapeutics , 5 :433 , 2008
PubMedID: 18625455

Title : In vitro metabolism of indiplon and an assessment of its drug interaction potential - Madan_2007_Xenobiotica_37_736
Author(s) : Madan A , Fisher A , Jin L , Chapman D , Bozigian HP
Ref : Xenobiotica , 37 :736 , 2007
PubMedID: 17620220

Title : M1 and M3 muscarinic receptors control physiological processing of cellular prion by modulating ADAM17 phosphorylation and activity - Alfa_2007_J.Neurosci_27_4083
Author(s) : Alfa Cisse M , Sunyach C , Slack BE , Fisher A , Vincent B , Checler F
Ref : Journal of Neuroscience , 27 :4083 , 2007
PubMedID: 17428986

Title : Poster (46) Major hallmarks in alzheimer's disease (ad) can beneficially be modulated by M1 muscarinic agonists - an added value vs. cholinesterase inhibitors -
Author(s) : Fisher A , Brandeis R , Pittel Z , Haring R , Sparks L , Beach TG , Bons N , Maestre-Frances N , Bar-Ner N , Kliger-Spatz M , Natan N , Marcovitch I , Hartmann T
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :345 , 2004
PubMedID:

Title : Reduction in distractibility with AF102B and THA in the macaque - O'Neill_2003_Pharmacol.Biochem.Behav_76_301
Author(s) : O'Neill J , Siembieda DW , Crawford KC , Halgren E , Fisher A , Fitten LJ
Ref : Pharmacol Biochem Behav , 76 :301 , 2003
PubMedID: 14592682

Title : M1 muscarinic agonists can modulate some of the hallmarks in Alzheimer's disease: implications in future therapy - Fisher_2003_J.Mol.Neurosci_20_349
Author(s) : Fisher A , Pittel Z , Haring R , Bar-Ner N , Kliger-Spatz M , Natan N , Egozi I , Sonego H , Marcovitch I , Brandeis R
Ref : Journal of Molecular Neuroscience , 20 :349 , 2003
PubMedID: 14501019

Title : M1 muscarinic agonists as potential disease-modifying agents in Alzheimer's disease. Rationale and perspectives - Fisher_2000_Ann.N.Y.Acad.Sci_920_315
Author(s) : Fisher A , Michaelson DM , Brandeis R , Haring R , Chapman S , Pittel Z
Ref : Annals of the New York Academy of Sciences , 920 :315 , 2000
PubMedID: 11193170

Title : Therapeutic strategies in Alzheimer's disease: M1 muscarinic agonists - Fisher_2000_Jpn.J.Pharmacol_84_101
Author(s) : Fisher A
Ref : Japanese Journal of Pharmacology , 84 :101 , 2000
PubMedID: 11128032

Title : Divided attention-enhancing effects of AF102B and THA in aging monkeys - O'Neill_1999_Psychopharmacology.(Berl)_143_123
Author(s) : O'Neill J , Fitten LJ , Siembieda DW , Crawford KC , Halgren E , Fisher A , Refai D
Ref : Psychopharmacology (Berl) , 143 :123 , 1999
PubMedID: 10326774

Title : Poster: Effect of muscarinic stimulation on beta-amyloid precursor protein processing in rat brain and primary cultures -
Author(s) : Pittel Z , Fisher A , Eshhar N , Haring R , Heldman E
Ref : Life Sciences , 64 :572 , 1999
PubMedID:

Title : Site-specific dephosphorylation of tau of apolipoprotein E-deficient and control mice by M1 muscarinic agonist treatment - Genis_1999_J.Neurochem_72_206
Author(s) : Genis I , Fisher A , Michaelson DM
Ref : Journal of Neurochemistry , 72 :206 , 1999
PubMedID: 9886071

Title : Reduction of motoric agitation and restlessness by AF102B and tacrine in the macaque - Fitten_1999_J.Neuropsychiatry.Clin.Neurosci_11_79
Author(s) : Fitten LJ , Ortiz F , Siembieda DW , O'Neill J , Halgren E , Fisher A
Ref : J Neuropsychiatry Clin Neurosci , 11 :79 , 1999
PubMedID: 9990560

Title : M1 muscarinic agonist treatment reverses cognitive and cholinergic impairments of apolipoprotein E-deficient mice - Fisher_1998_J.Neurochem_70_1991
Author(s) : Fisher A , Brandeis R , Chapman S , Pittel Z , Michaelson DM
Ref : Journal of Neurochemistry , 70 :1991 , 1998
PubMedID: 9572284

Title : Effects of AF102B and tacrine on delayed match-to-sample in monkeys - O'Neill_1998_Prog.Neuropsychopharmacol.Biol.Psychiatry_22_665
Author(s) : O'Neill J , Fitten LJ , Siembieda D , Halgren E , Kim E , Fisher A , Perryman K
Ref : Prog Neuropsychopharmacol Biological Psychiatry , 22 :665 , 1998
PubMedID: 9682279

Title : Novel m1 muscarinic agonists in treatment and delaying the progression of Alzheimer's disease: An unifying hypothesis - Fisher_1998_J.Physiol.Paris_92_337
Author(s) : Fisher A , Brandeis R , Haring R , Eshhar N , Heldman E , Karton Y , Eisenberg O , Meshulam H , Marciano D , Bar-Ner N , Pittel Z
Ref : Journal de Physiologie (Paris) , 92 :337 , 1998
PubMedID: 9789833

Title : The effects of the acetylcholinesterase inhibitor ENA713 and the M1 agonist AF150(S) on apolipoprotein E deficient mice - Chapman_1998_J.Physiol.Paris_92_299
Author(s) : Chapman S , Fisher A , Weinstock M , Brandies R , Shohami E , Michaelson DM
Ref : Journal de Physiologie Paris , 92 :299 , 1998
PubMedID: 9789827

Title : Poster: An M1 selective agonist AF102b, as a potential drug in treatment of Alzheimer's disease: Biochemical and pharmacological properties -
Author(s) : Haring R , Eshhar N , Heldman E , Marciano D , Kloog Y , Fisher A
Ref : Life Sciences , 60 :1183 , 1997
PubMedID:

Title : M1 agonists for the treatment of Alzheimer's disease. Novel properties and clinical update - Fisher_1996_Ann.N.Y.Acad.Sci_777_189
Author(s) : Fisher A , Heldman E , Gurwitz D , Haring R , Karton Y , Meshulam H , Pittel Z , Marciano D , Brandeis R , Sadot E , Barg Y , Pinkas-Kramarski R , Vogel Z , Ginzburg I , Treves TA , Verchovsky R , Klimowsky S , Korczyn AD
Ref : Annals of the New York Academy of Sciences , 777 :189 , 1996
PubMedID: 8624083

Title : Muscarinic control of amyloid precursor protein secretion in rat cerebral cortex and cerebellum - Pittel_1996_Brain.Res_742_299
Author(s) : Pittel Z , Heldman E , Barg J , Haring R , Fisher A
Ref : Brain Research , 742 :299 , 1996
PubMedID: 9117408

Title : Dehydroepiandrosterone (DHEA) increases production and release of Alzheimer's amyloid precursor protein - Danenberg_1996_Life.Sci_59_1651
Author(s) : Danenberg HD , Haring R , Fisher A , Pittel Z , Gurwitz D , Heldman E
Ref : Life Sciences , 59 :1651 , 1996
PubMedID: 8913330

Title : Dehydroepiandrosterone augments M1-muscarinic receptor-stimulated amyloid precursor protein secretion in desensitized PC12M1 cells - Danenberg_1995_Ann.N.Y.Acad.Sci_774_300
Author(s) : Danenberg HD , Haring R , Heldman E , Gurwitz D , Ben-Nathan D , Pittel Z , Zuckerman A , Fisher A
Ref : Annals of the New York Academy of Sciences , 774 :300 , 1995
PubMedID: 8597471

Title : Discrete activation of transduction pathways associated with acetylcholine m1 receptor by several muscarinic ligands - Gurwitz_1994_Eur.J.Pharmacol_267_21
Author(s) : Gurwitz D , Haring R , Heldman E , Fraser CM , Manor D , Fisher A
Ref : European Journal of Pharmacology , 267 :21 , 1994
PubMedID: 8206127

Title : Selective signaling via unique M1 muscarinic agonists - Fisher_1993_Ann.N.Y.Acad.Sci_695_300
Author(s) : Fisher A , Heldman E , Gurwitz D , Haring R , Barak D , Meshulam H , Marciano D , Brandeis R , Pittel Z , Segal M , et al.
Ref : Annals of the New York Academy of Sciences , 695 :300 , 1993
PubMedID: 8239299

Title : Progress in medicinal chemistry of novel selective muscarinic agonists - Fisher_1993_Drug.Des.Discov_9_221
Author(s) : Fisher A , Karton Y , Heldman E , Gurwitz D , Haring R , Meshulam H , Brandeis R , Pittel Z , Segall Y , Marciano D , et al.
Ref : Drug Des Discov , 9 :221 , 1993
PubMedID: 8400004

Title : Effects of muscarinic receptor agonists and anticholinesterase drugs on high voltage spindles and slow waves - Riekkinen_1993_Eur.J.Pharmacol_240_1
Author(s) : Riekkinen P, Jr. , Riekkinen M , Fisher A , Ekonsalo T , Sirvio J
Ref : European Journal of Pharmacology , 240 :1 , 1993
PubMedID: 8405117

Title : Poster: Transmembrane signaling of M1 muscarinic receptors in the rat brain and cell cultures -
Author(s) : Pittel Z , Fisher A , Vogel Z , Heldman E
Ref : Life Sciences , 52(5-6) :565 , 1993
PubMedID:

Title : Differential long-term effect of AF64A on [3H]ACh synthesis and release in rat hippocampal synaptosomes - Pittel_1992_Brain.Res_586_148
Author(s) : Pittel Z , Cohen S , Fisher A , Heldman E
Ref : Brain Research , 586 :148 , 1992
PubMedID: 1511344

Title : AF102B, a muscarinic M1 receptor agonist, mimics some effects of acetylcholine on neurons of rat hippocampus slices - Segal_1992_Eur.J.Pharmacol_220_103
Author(s) : Segal M , Fisher A
Ref : European Journal of Pharmacology , 220 :103 , 1992
PubMedID: 1425975

Title : Evidence of paired M2 muscarinic receptors - Potter_1991_Mol.Pharmacol_39_211
Author(s) : Potter LT , Ballesteros LA , Bichajian LH , Ferrendelli CA , Fisher A , Hanchett HE , Zhang R
Ref : Molecular Pharmacology , 39 :211 , 1991
PubMedID: 1899905

Title : (+-)-cis-2-methyl-spiro(1,3-oxathiolane-5,3')quinuclidine, an M1 selective cholinergic agonist, attenuates cognitive dysfunctions in an animal model of Alzheimer's disease - Fisher_1991_J.Pharmacol.Exp.Ther_257_392
Author(s) : Fisher A , Brandeis R , Karton I , Pittel Z , Gurwitz D , Haring R , Sapir M , Levy A , Heldman E
Ref : Journal of Pharmacology & Experimental Therapeutics , 257 :392 , 1991
PubMedID: 2019998

Title : Dual synaptic effects of activating M1-muscarinic receptors, in superior cervical ganglia of rabbits - Mochida_1988_Brain.Res_455_9
Author(s) : Mochida S , Mizobe F , Fisher A , Kawanishi G , Kobayashi H
Ref : Brain Research , 455 :9 , 1988
PubMedID: 2458168

Title : AF64A: an active site directed irreversible inhibitor of choline acetyltransferase - Sandberg_1985_J.Neurochem_44_439
Author(s) : Sandberg K , Schnaar RL , McKinney M , Hanin I , Fisher A , Coyle JT
Ref : Journal of Neurochemistry , 44 :439 , 1985
PubMedID: 3838098

Title : AF64A, a cholinergic neurotoxin, selectively depletes acetylcholine in hippocampus and cortex, and produces long-term passive avoidance and radial-arm maze deficits in the rat - Walsh_1984_Brain.Res_321_91
Author(s) : Walsh TJ , Tilson HA , DeHaven DL , Mailman RB , Fisher A , Hanin I
Ref : Brain Research , 321 :91 , 1984
PubMedID: 6548653

Title : Selective cholinergic neurotoxin: AF64A's effects in rat striatum - Sandberg_1984_Brain.Res_293_49
Author(s) : Sandberg K , Hanin I , Fisher A , Coyle JT
Ref : Brain Research , 293 :49 , 1984
PubMedID: 6142754

Title : Effects of the cholinotoxin, AF64A, on neuronal trace-metal distribution in the rat hippocampus and neocortex - Szerdahelyi_1984_Histochem_81_497
Author(s) : Szerdahelyi P , Kasa P , Fisher A , Hanin I
Ref : Histochemistry , 81 :497 , 1984
PubMedID: 6549180

Title : Possible mechanisms involved in the presynaptic cholinotoxicity due to ethylcholine aziridinium (AF64A) in vivo - Mantione_1984_Life.Sci_35_33
Author(s) : Mantione CR , Fisher A , Hanin I
Ref : Life Sciences , 35 :33 , 1984
PubMedID: 6330483

Title : Selective presynaptic cholinergic neurotoxicity following intrahippocampal AF64A injection in rats - Mantione_1983_J.Neurochem_41_251
Author(s) : Mantione CR , Zigmond MJ , Fisher A , Hanin I
Ref : Journal of Neurochemistry , 41 :251 , 1983
PubMedID: 6688090

Title : Selective inhibition of peripheral cholinergic transmission in the cat produced by AF64A - Mantione_1983_J.Pharmacol.Exp.Ther_225_616
Author(s) : Mantione CR , De Groat WC , Fisher A , Hanin I
Ref : Journal of Pharmacology & Experimental Therapeutics , 225 :616 , 1983
PubMedID: 6306213

Title : Long-term central cholinergic hypofunction induced in mice by ethylcholine aziridinium ion (AF64A) in vivo - Fisher_1982_J.Pharmacol.Exp.Ther_222_140
Author(s) : Fisher A , Mantione CR , Abraham DJ , Hanin I
Ref : Journal of Pharmacology & Experimental Therapeutics , 222 :140 , 1982
PubMedID: 6896342

Title : Does rigidity in structure of muscarinic agonists and antagonists reflect drug specificity? - Fisher_1980_Monogr.Neural.Sci_7_41
Author(s) : Fisher A , Abraham S , Lachman C , Lass Y , Akselrod S , Akerman E , Cohen S
Ref : Monogr Neural Sci , 7 :41 , 1980
PubMedID: 7231438

Title : Choline analogs as potential tools in developing selective animal models of central cholinergic hypofunction -
Author(s) : Fisher A , Hanin I
Ref : Life Sciences , 27 :1615 , 1980
PubMedID: 7003285

Title : Offset rate of action of muscarinic antagonists depends on their structural flexibility - Lass_1979_Experientia_35_650
Author(s) : Lass Y , Akselrod S , Gavish B , Cohen S , Fisher A
Ref : Experientia , 35 :650 , 1979
PubMedID: 446670

Title : A study of muscarinic receptor heterogeneity with weak antagonists - Fisher_1976_Eur.J.Pharmacol_38_131
Author(s) : Fisher A , Grunfeld Y , Weinstock M , Gitter S , Cohen S
Ref : European Journal of Pharmacology , 38 :131 , 1976
PubMedID: 954822