| Title : Phenotype in Individuals with Heterozygous Rare Variants in LIPC Encoding Hepatic Lipase - Jacob_2024_Int.J.Mol.Sci_25_11445 |
| Author(s) : Jacob EO , Wang J , McIntyre AD , Hegele RA |
| Ref : Int J Mol Sci , 25 :11445 , 2024 |
| Abstract : |
| PubMedSearch : Jacob_2024_Int.J.Mol.Sci_25_11445 |
| PubMedID: 39518997 |
| Gene_locus related to this paper: human-LIPC |
| Title : Soluble Epoxide Hydrolase Derived Linoleic Acid Oxylipins, Small Vessel Disease Markers, and Neurodegeneration in Stroke - Yu_2023_J.Am.Heart.Assoc_12_e026901 |
| Author(s) : Yu D , Liang N , Zebarth J , Shen Q , Ozzoude M , Goubran M , Rabin JS , Ramirez J , Scott CJM , Gao F , Bartha R , Symons S , Haddad SMH , Berezuk C , Tan B , Kwan D , Hegele RA , Dilliott AA , Nanayakkara ND , Binns MA , Beaton D , Arnott SR , Lawrence-Dewar JM , Hassan A , Dowlatshahi D , Mandzia J , Sahlas D , Casaubon L , Saposnik G , Otoki Y , Lanctot KL , Masellis M , Black SE , Swartz RH , Taha AY , Swardfager W |
| Ref : J Am Heart Assoc , 12 :e026901 , 2023 |
| Abstract : |
| PubMedSearch : Yu_2023_J.Am.Heart.Assoc_12_e026901 |
| PubMedID: 36583428 |
| Title : The longitudinal triglyceride phenotype in heterozygotes with LPL pathogenic variants - Perera_2022_J.Clin.Lipidol__ |
| Author(s) : Perera SD , Wang J , McIntyre AD , Dron JS , Hegele RA |
| Ref : J Clin Lipidol , : , 2022 |
| Abstract : |
| PubMedSearch : Perera_2022_J.Clin.Lipidol__ |
| PubMedID: 36476373 |
| Title : Volanesorsen for treatment of familial chylomicronemia syndrome - Lazarte_2021_Expert.Rev.Cardiovasc.Ther_19_685 |
| Author(s) : Lazarte J , Hegele RA |
| Ref : Expert Rev Cardiovasc Ther , 19 :685 , 2021 |
| Abstract : |
| PubMedSearch : Lazarte_2021_Expert.Rev.Cardiovasc.Ther_19_685 |
| PubMedID: 34261380 |
| Title : Novel therapeutics in hypertriglyceridemia - Gryn_2015_Curr.Opin.Lipidol_26_484 |
| Author(s) : Gryn SE , Hegele RA |
| Ref : Curr Opin Lipidol , 26 :484 , 2015 |
| Abstract : |
| PubMedSearch : Gryn_2015_Curr.Opin.Lipidol_26_484 |
| PubMedID: 26780002 |
| Title : Severe Hypertriglyceridemia due to a novel p.Q240H mutation in the Lipoprotein Lipase gene - Soto_2015_Lipids.Health.Dis_14_102 |
| Author(s) : Soto AG , McIntyre A , Agrawal S , Bialo SR , Hegele RA , Boney CM |
| Ref : Lipids Health Dis , 14 :102 , 2015 |
| Abstract : |
| PubMedSearch : Soto_2015_Lipids.Health.Dis_14_102 |
| PubMedID: 26337181 |
| Gene_locus related to this paper: human-LPL |
| Title : Partial lipodystrophy associated with muscular dystrophy of unknown genetic origin - |
| Author(s) : Carboni N , Brancati F , Cocco E , Solla E , D'Apice MR , Mateddu A , McIntyre A , Fadda E , Mura M , Lattanzi G , Piras R , Maioli MA , Marrosu G , Novelli G , Marrosu MG , Hegele RA |
| Ref : Muscle & Nerve , 49 :928 , 2014 |
| PubMedID: 24375490 |
| Gene_locus related to this paper: human-LIPE |
| Title : A novel LIPE nonsense mutation found using exome sequencing in siblings with late-onset familial partial lipodystrophy - Farhan_2014_Can.J.Cardiol_30_1649 |
| Author(s) : Farhan SM , Robinson JF , McIntyre AD , Marrosu MG , Ticca AF , Loddo S , Carboni N , Brancati F , Hegele RA |
| Ref : Can J Cardiol , 30 :1649 , 2014 |
| Abstract : |
| PubMedSearch : Farhan_2014_Can.J.Cardiol_30_1649 |
| PubMedID: 25475467 |
| Gene_locus related to this paper: human-LIPE |
| Title : Mutations in LPL, APOC2, APOA5, GPIHBP1 and LMF1 in patients with severe hypertriglyceridaemia - Surendran_2012_J.Intern.Med_272_185 |
| Author(s) : Surendran RP , Visser ME , Heemelaar S , Wang J , Peter J , Defesche JC , Kuivenhoven JA , Hosseini M , Peterfy M , Kastelein JJ , Johansen CT , Hegele RA , Stroes ES , Dallinga-Thie GM |
| Ref : J Intern Med , 272 :185 , 2012 |
| Abstract : |
| PubMedSearch : Surendran_2012_J.Intern.Med_272_185 |
| PubMedID: 22239554 |
| Gene_locus related to this paper: human-LPL |
| Title : Loss-of-function variants in endothelial lipase are a cause of elevated HDL cholesterol in humans - Edmondson_2009_J.Clin.Invest_119_1042 |
| Author(s) : Edmondson AC , Brown RJ , Kathiresan S , Cupples LA , Demissie S , Manning AK , Jensen MK , Rimm EB , Wang J , Rodrigues A , Bamba V , Khetarpal SA , Wolfe ML , Derohannessian S , Li M , Reilly MP , Aberle J , Evans D , Hegele RA , Rader DJ |
| Ref : J Clinical Investigation , 119 :1042 , 2009 |
| Abstract : |
| PubMedSearch : Edmondson_2009_J.Clin.Invest_119_1042 |
| PubMedID: 19287092 |
| Gene_locus related to this paper: human-LIPG |
| Title : Novel LPL mutations associated with lipoprotein lipase deficiency: two case reports and a literature review - Rahalkar_2009_Can.J.Physiol.Pharmacol_87_151 |
| Author(s) : Rahalkar AR , Giffen F , Har B , Ho J , Morrison KM , Hill J , Wang J , Hegele RA , Joy T |
| Ref : Canadian Journal of Physiology & Pharmacology , 87 :151 , 2009 |
| Abstract : |
| PubMedSearch : Rahalkar_2009_Can.J.Physiol.Pharmacol_87_151 |
| PubMedID: 19295657 |
| Gene_locus related to this paper: human-LPL |
| Title : Stability of lipids on peritoneal dialysis in a patient with familial LCAT deficiency - |
| Author(s) : Weber CL , Frohlich J , Wang J , Hegele RA , Chan-Yan C |
| Ref : Nephrol Dial Transplant , 22 :2084 , 2007 |
| PubMedID: 17452402 |
| Title : Resequencing genomic DNA of patients with severe hypertriglyceridemia (MIM 144650) - Wang_2007_Arterioscler.Thromb.Vasc.Biol_27_2450 |
| Author(s) : Wang J , Cao H , Ban MR , Kennedy BA , Zhu S , Anand S , Yusuf S , Pollex RL , Hegele RA |
| Ref : Arterioscler Thromb Vasc Biol , 27 :2450 , 2007 |
| Abstract : |
| PubMedSearch : Wang_2007_Arterioscler.Thromb.Vasc.Biol_27_2450 |
| PubMedID: 17717288 |
| Gene_locus related to this paper: human-LPL |
| Title : Treatment of dyslipidemia with lovastatin and ezetimibe in an adolescent with cholesterol ester storage disease - Tadiboyina_2005_Lipids.Health.Dis_4_26 |
| Author(s) : Tadiboyina VT , Liu DM , Miskie BA , Wang J , Hegele RA |
| Ref : Lipids Health Dis , 4 :26 , 2005 |
| Abstract : |
| PubMedSearch : Tadiboyina_2005_Lipids.Health.Dis_4_26 |
| PubMedID: 16255772 |
| Title : Identification of a novel lipase gene mutated in lpd mice with hypertriglyceridemia and associated with dyslipidemia in humans - Wen_2003_Hum.Mol.Genet_12_1131 |
| Author(s) : Wen XY , Hegele RA , Wang J , Wang DY , Cheung J , Wilson M , Yahyapour M , Bai Y , Zhuang L , Skaug J , Young TK , Connelly PW , Koop BF , Tsui LC , Stewart AK |
| Ref : Hum Mol Genet , 12 :1131 , 2003 |
| Abstract : |
| PubMedSearch : Wen_2003_Hum.Mol.Genet_12_1131 |
| PubMedID: 12719377 |
| Gene_locus related to this paper: human-LIPI |
| Title : DNA polymorphisms of lipase related genes - Cao_2003_J.Hum.Genet_48_443 |
| Author(s) : Cao H , Hegele RA |
| Ref : J Hum Genet , 48 :443 , 2003 |
| Abstract : |
| PubMedSearch : Cao_2003_J.Hum.Genet_48_443 |
| PubMedID: 12898288 |
| Title : Characterization of a novel mutation causing hepatic lipase deficiency among French Canadians - Ruel_2003_J.Lipid.Res_44_1508 |
| Author(s) : Ruel IL , Couture P , Gagne C , Deshaies Y , Simard J , Hegele RA , Lamarche B |
| Ref : J Lipid Res , 44 :1508 , 2003 |
| Abstract : |
| PubMedSearch : Ruel_2003_J.Lipid.Res_44_1508 |
| PubMedID: 12777476 |
| Gene_locus related to this paper: human-LIPC |
| Title : Polymorphisms in the gene encoding phosphatidylserine-specific phospholipase A1 ( PSPLA1) - Wang_2002_J.Hum.Genet_47_611 |
| Author(s) : Wang J , Wen XY , Stewart AK , Hegele RA |
| Ref : J Hum Genet , 47 :611 , 2002 |
| Abstract : |
| PubMedSearch : Wang_2002_J.Hum.Genet_47_611 |
| PubMedID: 12436198 |
| Title : Polymorphisms in PNLIP, encoding pancreatic lipase, and associations with metabolic traits - Hegele_2001_J.Hum.Genet_46_320 |
| Author(s) : Hegele RA , Ramdath DD , Ban MR , Carruthers MN , Carrington CV , Cao H |
| Ref : J Hum Genet , 46 :320 , 2001 |
| Abstract : |
| PubMedSearch : Hegele_2001_J.Hum.Genet_46_320 |
| PubMedID: 11393534 |
| Title : Absence of association between genetic variation in the LIPC gene promoter and plasma lipoproteins in three Canadian populations - Hegele_1999_Atherosclerosis_146_153 |
| Author(s) : Hegele RA , Harris SB , Brunt JH , Young TK , Hanley AJ , Zinman B , Connelly PW |
| Ref : Atherosclerosis , 146 :153 , 1999 |
| Abstract : |
| PubMedSearch : Hegele_1999_Atherosclerosis_146_153 |
| PubMedID: 10487498 |
| Title : Atorvastatin in the management of an index patient with complete hepatic lipase deficiency - |
| Author(s) : Hegele RA , Little JA , Connelly PW |
| Ref : Atherosclerosis , 143 :219 , 1999 |
| PubMedID: 10208500 |
| Title : Elevated LDL triglyceride concentrations in subjects heterozygous for the hepatic lipase S267F variant - Hegele_1998_Arterioscler.Thromb.Vasc.Biol_18_1212 |
| Author(s) : Hegele RA , Breckenridge WC , Cox DW , Maguire GF , Little JA , Connelly PW |
| Ref : Arterioscler Thromb Vasc Biol , 18 :1212 , 1998 |
| Abstract : |
| PubMedSearch : Hegele_1998_Arterioscler.Thromb.Vasc.Biol_18_1212 |
| PubMedID: 9714127 |
| Title : Beta-VLDL in hepatic lipase deficiency induces apoE-mediated cholesterol ester accumulation in macrophages - Huff_1993_Arterioscler.Thromb_13_1282 |
| Author(s) : Huff MW , Sawyez CG , Connelly PW , Maguire GF , Little JA , Hegele RA |
| Ref : Arterioscler Thromb , 13 :1282 , 1993 |
| Abstract : |
| PubMedSearch : Huff_1993_Arterioscler.Thromb_13_1282 |
| PubMedID: 8364012 |
| Title : Hepatic lipase deficiency. Clinical, biochemical, and molecular genetic characteristics - Hegele_1993_Arterioscler.Thromb_13_720 |
| Author(s) : Hegele RA , Little JA , Vezina C , Maguire GF , Tu L , Wolever TS , Jenkins DJ , Connelly PW |
| Ref : Arterioscler Thromb , 13 :720 , 1993 |
| Abstract : |
| PubMedSearch : Hegele_1993_Arterioscler.Thromb_13_720 |
| PubMedID: 8485124 |
| Title : Human hepatic lipase mutations and polymorphisms - Hegele_1992_Hum.Mutat_1_320 |
| Author(s) : Hegele RA , Tu L , Connelly PW |
| Ref : Hum Mutat , 1 :320 , 1992 |
| Abstract : |
| PubMedSearch : Hegele_1992_Hum.Mutat_1_320 |
| PubMedID: 1301939 |
| Title : Compound heterozygosity for mutant hepatic lipase in familial hepatic lipase deficiency - Hegele_1991_Biochem.Biophys.Res.Commun_179_78 |
| Author(s) : Hegele RA , Little JA , Connelly PW |
| Ref : Biochemical & Biophysical Research Communications , 179 :78 , 1991 |
| Abstract : |
| PubMedSearch : Hegele_1991_Biochem.Biophys.Res.Commun_179_78 |
| PubMedID: 1883393 |
| Title : A hepatic lipase gene mutation associated with heritable lipolytic deficiency - Hegele_1991_J.Clin.Endocrinol.Metab_72_730 |
| Author(s) : Hegele RA , Vezina C , Moorjani S , Lupien PJ , Gagne C , Brun LD , Little JA , Connelly PW |
| Ref : J Clinical Endocrinology Metab , 72 :730 , 1991 |
| Abstract : |
| PubMedSearch : Hegele_1991_J.Clin.Endocrinol.Metab_72_730 |
| PubMedID: 1671786 |