Zheng F

General

Full name : Zheng Fang

First name : Fang

Mail : Molecular Modelling and Biopharmaceutical Center and Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, 789 South Limestone Street, Lexington, KY 40536

Zip Code :

City :

Country : USA

Email : fzhen2@email.uky.edu

Phone :

Fax :

Website :

Directory :

References (65)

Title : In vitro and in vivo stability of a highly efficient long-acting cocaine hydrolase - Shang_2024_Sci.Rep_14_10952
Author(s) : Shang L , Wei H , Deng J , Stewart MJ , LeSaint JE , Kyomuhangi A , Park S , Maul EC , Zhan CG , Zheng F
Ref : Sci Rep , 14 :10952 , 2024
PubMedID: 38740850

Title : Long-lasting blocking of interoceptive effects of cocaine by a highly efficient cocaine hydrolase in rats - Wei_2024_Sci.Rep_14_927
Author(s) : Wei H , LeSaint JE , Jin Z , Zhan CG , Zheng F
Ref : Sci Rep , 14 :927 , 2024
PubMedID: 38195724

Title : Human Butyrylcholinesterase Mutants for (-)-Cocaine Hydrolysis: A Correlation Relationship between Catalytic Efficiency and Total Hydrogen Bonding Energy with an Oxyanion Hole - Zheng_2023_J.Phys.Chem.B__
Author(s) : Zheng F , Hou S , Xue L , Yang W , Zhan CG
Ref : J Phys Chem B , : , 2023
PubMedID: 38063500

Title : Recovery of dopaminergic system after cocaine exposure and impact of a long-acting cocaine hydrolase - Deng_2022_Addict.Biol_27_e13179
Author(s) : Deng J , Zhang T , Zheng X , Shang L , Zhan CG , Zheng F
Ref : Addict Biol , 27 :e13179 , 2022
PubMedID: 35754103

Title : Development of a Highly Efficient Long-Acting Cocaine Hydrolase Entity to Accelerate Cocaine Metabolism - Zheng_2022_Bioconjug.Chem__
Author(s) : Zheng F , Jin Z , Deng J , Chen X , Zheng X , Wang G , Kim K , Shang L , Zhou Z , Zhan CG
Ref : Bioconjug Chem , : , 2022
PubMedID: 35767675

Title : Effects of alcohol on metabolism and toxicity of cocaine in rats - Shang_2022_Toxicol.Rep_9_1586
Author(s) : Shang L , Zheng X , Zhang T , Deng J , Zhan CG , Zheng F
Ref : Toxicol Rep , 9 :1586 , 2022
PubMedID: 36518391

Title : Catalytic activities of cocaine hydrolases against the most toxic cocaine metabolite norcocaethylene - Zheng_2020_Org.Biomol.Chem__
Author(s) : Zheng X , Chen X , Zhang T , Zhan M , Zhan CG , Zheng F
Ref : Org Biomol Chem , : , 2020
PubMedID: 32101217

Title : Efficient Cocaine Degradation by Cocaine Esterase-Loaded Red Blood Cells - Rossi_2020_Front.Physiol_11_573492
Author(s) : Rossi L , Pierige F , Agostini M , Bigini N , Termopoli V , Cai Y , Zheng F , Zhan CG , Landry DW , Magnani M
Ref : Front Physiol , 11 :573492 , 2020
PubMedID: 33013487

Title : Identification of ovalbumin-derived peptides as multi-target inhibitors of AChE, BChE and BACE1 - Yu_2020_J.Sci.Food.Agric__
Author(s) : Yu Z , Dong W , Wu S , Shen J , Zhao W , Ding L , Liu J , Zheng F
Ref : J Sci Food Agric , : , 2020
PubMedID: 31997357

Title : Structure-based virtual screening leading to discovery of highly selective butyrylcholinesterase inhibitors with solanaceous alkaloid scaffolds - Zhou_2019_Chem.Biol.Interact_13ChEPon_308_372
Author(s) : Zhou S , Yuan Y , Zheng F , Zhan CG
Ref : Chemico-Biological Interactions , 308 :372 , 2019
PubMedID: 31152736

Title : Reengineering of Albumin-Fused Cocaine Hydrolase CocH1 (TV-1380) to Prolong Its Biological Half-Life - Cai_2019_AAPS.J_22_5
Author(s) : Cai Y , Zhou S , Jin Z , Wei H , Shang L , Deng J , Zhan CG , Zheng F
Ref : AAPS J , 22 :5 , 2019
PubMedID: 31754920

Title : Development of a long-acting Fc-fused cocaine hydrolase with improved yield of protein expression - Chen_2019_Chem.Biol.Interact_13ChEPon_306_89
Author(s) : Chen X , Deng J , Zheng X , Zhang J , Zhou Z , Wei H , Zhan CG , Zheng F
Ref : Chemico-Biological Interactions , 306 :89 , 2019
PubMedID: 30986387

Title : Dimerization of human butyrylcholinesterase expressed in bacterium for development of a thermally stable bioscavenger of organophosphorus compounds - Cai_2019_Chem.Biol.Interact_13ChEPon_310_108756
Author(s) : Cai Y , Zhou S , Stewart MJ , Zheng F , Zhan CG
Ref : Chemico-Biological Interactions , 310 :108756 , 2019
PubMedID: 31325422

Title : Assessment of phthalate ester residues and distribution patterns in Baijiu raw materials and Baijiu - Dong_2019_Food.Chem_283_508
Author(s) : Dong W , Guo R , Sun X , Li H , Zhao M , Zheng F , Sun J , Huang M , Wu J
Ref : Food Chem , 283 :508 , 2019
PubMedID: 30722905

Title : Draft genome sequence of Camellia sinensis var. sinensis provides insights into the evolution of the tea genome and tea quality - Wei_2018_Proc.Natl.Acad.Sci.U.S.A_115_E4151
Author(s) : Wei C , Yang H , Wang S , Zhao J , Liu C , Gao L , Xia E , Lu Y , Tai Y , She G , Sun J , Cao H , Tong W , Gao Q , Li Y , Deng W , Jiang X , Wang W , Chen Q , Zhang S , Li H , Wu J , Wang P , Li P , Shi C , Zheng F , Jian J , Huang B , Shan D , Shi M , Fang C , Yue Y , Li F , Li D , Wei S , Han B , Jiang C , Yin Y , Xia T , Zhang Z , Bennetzen JL , Zhao S , Wan X
Ref : Proc Natl Acad Sci U S A , 115 :E4151 , 2018
PubMedID: 29678829
Gene_locus related to this paper: camsi-a0a4s4dr18 , camsi-a0a4s4etg9 , camsi-a0a4s4e3j5 , camsi-a0a4s4d2s5 , camsi-a0a4s4duc4 , camsi-a0a4v3wr80 , camsi-a0a4v3wpu4

Title : Catalytic Reaction Mechanism for Drug Metabolism in Human Carboxylesterase-1: Cocaine Hydrolysis Pathway - Yao_2018_Mol.Pharm_15_3871
Author(s) : Yao J , Chen X , Zheng F , Zhan CG
Ref : Mol Pharm , 15 :3871 , 2018
PubMedID: 30095924

Title : Kinetic characterization of cholinesterases and a therapeutically valuable cocaine hydrolase for their catalytic activities against heroin and its metabolite 6-monoacetylmorphine - Kim_2018_Chem.Biol.Interact_293_107
Author(s) : Kim K , Yao J , Jin Z , Zheng F , Zhan CG
Ref : Chemico-Biological Interactions , 293 :107 , 2018
PubMedID: 30080993

Title : Metabolic Enzymes of Cocaine Metabolite Benzoylecgonine - Chen_2016_ACS.Chem.Biol_11_2186
Author(s) : Chen X , Zheng X , Zhan M , Zhou Z , Zhan CG , Zheng F
Ref : ACS Chemical Biology , 11 :2186 , 2016
PubMedID: 27224254

Title : Effects of a cocaine hydrolase engineered from human butyrylcholinesterase on metabolic profile of cocaine in rats - Chen_2016_Chem.Biol.Interact_259_104
Author(s) : Chen X , Zheng X , Zhou Z , Zhan CG , Zheng F
Ref : Chemico-Biological Interactions , 259 :104 , 2016
PubMedID: 27154495

Title : Potential anti-obesity effects of a long-acting cocaine hydrolase - Zheng_2016_Chem.Biol.Interact_259_99
Author(s) : Zheng X , Deng J , Zhang T , Yao J , Zheng F , Zhan CG
Ref : Chemico-Biological Interactions , 259 :99 , 2016
PubMedID: 27163854

Title : Free energy profiles of cocaine esterase-cocaine binding process by molecular dynamics and potential of mean force simulations - Zhang_2016_Chem.Biol.Interact_259_142
Author(s) : Zhang Y , Huang X , Han K , Zheng F , Zhan CG
Ref : Chemico-Biological Interactions , 259 :142 , 2016
PubMedID: 27163853

Title : Unexpected Reaction Pathway for butyrylcholinesterase-catalyzed inactivation of hunger hormone ghrelin - Yao_2016_Sci.Rep_6_22322
Author(s) : Yao J , Yuan Y , Zheng F , Zhan CG
Ref : Sci Rep , 6 :22322 , 2016
PubMedID: 26922910

Title : Kinetic characterization of a cocaine hydrolase engineered from mouse butyrylcholinesterase - Chen_2015_Biochem.J_466_243
Author(s) : Chen X , Huang X , Geng L , Xue L , Hou S , Zheng X , Brimijoin S , Zheng F , Zhan CG
Ref : Biochemical Journal , 466 :243 , 2015
PubMedID: 25486543
Gene_locus related to this paper: human-BCHE

Title : Rational design, preparation, and characterization of a therapeutic enzyme mutant with improved stability and function for cocaine detoxification - Fang_2014_ACS.Chem.Biol_9_1764
Author(s) : Fang L , Chow KM , Hou S , Xue L , Chen X , Rodgers DW , Zheng F , Zhan CG
Ref : ACS Chemical Biology , 9 :1764 , 2014
PubMedID: 24919140
Gene_locus related to this paper: rhosm-cocE

Title : Modeling in vitro inhibition of butyrylcholinesterase using molecular docking, multi-linear regression and artificial neural network approaches - Zheng_2014_Bioorg.Med.Chem_22_538
Author(s) : Zheng F , Zhan M , Huang X , Abdul Hameed MD , Zhan CG
Ref : Bioorganic & Medicinal Chemistry , 22 :538 , 2014
PubMedID: 24290065

Title : Kinetic characterization of human butyrylcholinesterase mutants for the hydrolysis of cocaethylene - Hou_2014_Biochem.J_460_447
Author(s) : Hou S , Zhan M , Zheng X , Zhan CG , Zheng F
Ref : Biochemical Journal , 460 :447 , 2014
PubMedID: 24870023

Title : GW1929 inhibits alpha7 nAChR expression through PPARgamma-independent activation of p38 MAPK and inactivation of PI3-K\/mTOR: The role of Egr-1 - Hahn_2014_Cell.Signal_26_730
Author(s) : Hahn SS , Tang Q , Zheng F , Zhao S , Wu J
Ref : Cell Signal , 26 :730 , 2014
PubMedID: 24412748

Title : Kinetic characterization of high-activity mutants of human butyrylcholinesterase for the cocaine metabolite norcocaine - Zhan_2014_Biochem.J_457_197
Author(s) : Zhan M , Hou S , Zhan CG , Zheng F
Ref : Biochemical Journal , 457 :197 , 2014
PubMedID: 24125115

Title : A highly efficient cocaine-detoxifying enzyme obtained by computational design - Zheng_2014_Nat.Commun_5_3457
Author(s) : Zheng F , Xue L , Hou S , Liu J , Zhan M , Yang W , Zhan CG
Ref : Nat Commun , 5 :3457 , 2014
PubMedID: 24643289
Gene_locus related to this paper: human-BCHE

Title : Amino-acid mutations to extend the biological half-life of a therapeutically valuable mutant of human butyrylcholinesterase - Fang_2014_Chem.Biol.Interact_214C_18
Author(s) : Fang L , Hou S , Xue L , Zheng F , Zhan CG
Ref : Chemico-Biological Interactions , 214C :18 , 2014
PubMedID: 24582612
Gene_locus related to this paper: human-BCHE

Title : Joint neurodevelopmental and behavioral effects of nonylphenol and estradiol on F1 male rats - Jie_2013_Int.J.Environ.Health.Res_23_321
Author(s) : Jie Y , Fan QY , Binli H , Biao Z , Zheng F , Jianmei L , Jie X
Ref : Int J Environ Health Res , 23 :321 , 2013
PubMedID: 23289371

Title : Catalytic activities of a cocaine hydrolase engineered from human butyrylcholinesterase against (+)- and (-)-cocaine - Xue_2013_Chem.Biol.Interact_203_57
Author(s) : Xue L , Hou S , Yang W , Fang L , Zheng F , Zhan CG
Ref : Chemico-Biological Interactions , 203 :57 , 2013
PubMedID: 22917637

Title : Preparation and in vivo characterization of a cocaine hydrolase engineered from human butyrylcholinesterase for metabolizing cocaine - Xue_2013_Biochem.J_453_447
Author(s) : Xue L , Hou S , Tong M , Fang L , Chen X , Jin Z , Tai HH , Zheng F , Zhan CG
Ref : Biochemical Journal , 453 :447 , 2013
PubMedID: 23849058

Title : Substrate selectivity of high-activity mutants of human butyrylcholinesterase - Hou_2013_Org.Biomol.Chem_11_7477
Author(s) : Hou S , Xue L , Yang W , Fang L , Zheng F , Zhan CG
Ref : Org Biomol Chem , 11 :7477 , 2013
PubMedID: 24077614

Title : A model of glycosylated human butyrylcholinesterase - Fang_2013_Mol.Biosyst_10_348
Author(s) : Fang L , Zheng F , Zhan CG
Ref : Mol Biosyst , 10 :348 , 2013
PubMedID: 24327294

Title : Cocaine esterase-cocaine binding process and the free energy profiles by molecular dynamics and potential of mean force simulations - Huang_2012_J.Phys.Chem.B_116_3361
Author(s) : Huang X , Zhao X , Zheng F , Zhan CG
Ref : J Phys Chem B , 116 :3361 , 2012
PubMedID: 22385120

Title : Modeling of pharmacokinetics of cocaine in human reveals the feasibility for development of enzyme therapies for drugs of abuse - Zheng_2012_PLoS.Comput.Biol_8_e1002610
Author(s) : Zheng F , Zhan CG
Ref : PLoS Comput Biol , 8 :e1002610 , 2012
PubMedID: 22844238

Title : Crystal structure of FAS thioesterase domain with polyunsaturated fatty acyl adduct and inhibition by dihomo-gamma-linolenic acid - Zhang_2011_Proc.Natl.Acad.Sci.U.S.A_108_15757
Author(s) : Zhang W , Chakravarty B , Zheng F , Gu Z , Wu H , Mao J , Wakil SJ , Quiocho FA
Ref : Proc Natl Acad Sci U S A , 108 :15757 , 2011
PubMedID: 21908709
Gene_locus related to this paper: human-FASN

Title : Design, synthesis and interaction at the vesicular monoamine transporter-2 of lobeline analogs: potential pharmacotherapies for the treatment of psychostimulant abuse - Crooks_2011_Curr.Top.Med.Chem_11_1103
Author(s) : Crooks PA , Zheng G , Vartak AP , Culver JP , Zheng F , Horton DB , Dwoskin LP
Ref : Curr Top Med Chem , 11 :1103 , 2011
PubMedID: 21050177

Title : Enzyme-therapy approaches for the treatment of drug overdose and addiction -
Author(s) : Zheng F , Zhan CG
Ref : Future Med Chem , 3 :9 , 2011
PubMedID: 21428822

Title : Human butyrylcholinesterase-cocaine binding pathway and free energy profiles by molecular dynamics and potential of mean force simulations - Huang_2011_J.Phys.Chem.B_115_11254
Author(s) : Huang X , Zheng F , Zhan CG
Ref : J Phys Chem B , 115 :11254 , 2011
PubMedID: 21902185

Title : Design, preparation, and characterization of high-activity mutants of human butyrylcholinesterase specific for detoxification of cocaine - Xue_2011_Mol.Pharmacol_79_290
Author(s) : Xue L , Ko MC , Tong M , Yang W , Hou S , Fang L , Liu J , Zheng F , Woods JH , Tai HH , Zhan CG
Ref : Molecular Pharmacology , 79 :290 , 2011
PubMedID: 20971807

Title : Free energy perturbation simulation on transition states and high-activity mutants of human butyrylcholinesterase for (-)-cocaine hydrolysis - Yang_2010_J.Phys.Chem.B_114_10889
Author(s) : Yang W , Pan Y , Fang L , Gao D , Zheng F , Zhan CG
Ref : J Phys Chem B , 114 :10889 , 2010
PubMedID: 20677742

Title : Design of high-activity mutants of human butyrylcholinesterase against (-)-cocaine: structural and energetic factors affecting the catalytic efficiency - Zheng_2010_Biochemistry_49_9113
Author(s) : Zheng F , Yang W , Xue L , Hou S , Liu J , Zhan CG
Ref : Biochemistry , 49 :9113 , 2010
PubMedID: 20886866

Title : Reaction pathway and free energy profile for prechemical reaction step of human butyrylcholinesterase-catalyzed hydrolysis of (-)-cocaine by combined targeted molecular dynamics and potential of mean force simulations - Huang_2010_J.Phys.Chem.B_114_13545
Author(s) : Huang X , Pan Y , Zheng F , Zhan CG
Ref : J Phys Chem B , 114 :13545 , 2010
PubMedID: 20883001

Title : A novel selective muscarinic acetylcholine receptor subtype 1 antagonist reduces seizures without impairing hippocampus-dependent learning - Sheffler_2009_Mol.Pharmacol_76_356
Author(s) : Sheffler DJ , Williams R , Bridges TM , Xiang Z , Kane AS , Byun NE , Jadhav S , Mock MM , Zheng F , Lewis LM , Jones CK , Niswender CM , Weaver CD , Lindsley CW , Conn PJ
Ref : Molecular Pharmacology , 76 :356 , 2009
PubMedID: 19407080

Title : Inactivation of dipeptidyl peptidase IV attenuates the virulence of Streptococcus suis serotype 2 that causes streptococcal toxic shock syndrome - Ge_2009_Curr.Microbiol_59_248
Author(s) : Ge J , Feng Y , Ji H , Zhang H , Zheng F , Wang C , Yin Z , Pan X , Tang J
Ref : Curr Microbiol , 59 :248 , 2009
PubMedID: 19484301

Title : Discovery and development of a potent and highly selective small molecule muscarinic acetylcholine receptor subtype I (mAChR 1 or M1) antagonist in vitro and in vivo probe - Weaver_2009_Curr.Top.Med.Chem_9_1217
Author(s) : Weaver CD , Sheffler DJ , Lewis LM , Bridges TM , Williams R , Nalywajko NT , Kennedy JP , Mulder MM , Jadhav S , Aldrich LA , Jones CK , Marlo JE , Niswender CM , Mock MM , Zheng F , Conn PJ , Lindsley CW
Ref : Curr Top Med Chem , 9 :1217 , 2009
PubMedID: 19807667

Title : Recent progress in protein drug design and discovery with a focus on novel approaches to the development of anti-cocaine medications - Zheng_2009_Future.Med.Chem_1_515
Author(s) : Zheng F , Zhan CG
Ref : Future Med Chem , 1 :515 , 2009
PubMedID: 20161378

Title : First-Principles Determination of Molecular Conformations of Indolizidine (-)-235B' in Solution - Zheng_2009_Theor.Chem.Acc_124_269
Author(s) : Zheng F , Dwoskin LP , Crooks PA , Zhan CG
Ref : Theor Chem Acc , 124 :269 , 2009
PubMedID: 20161506

Title : QSAR study on maximal inhibition (Imax) of quaternary ammonium antagonists for S-(-)-nicotine-evoked dopamine release from dopaminergic nerve terminals in rat striatum - Zheng_2009_Bioorg.Med.Chem_17_4477
Author(s) : Zheng F , McConnell MJ , Zhan CG , Dwoskin LP , Crooks PA
Ref : Bioorganic & Medicinal Chemistry , 17 :4477 , 2009
PubMedID: 19477134

Title : Computational neural network analysis of the affinity of N-n-alkylnicotinium salts for the alpha4beta2* nicotinic acetylcholine receptor - Zheng_2009_J.Enzyme.Inhib.Med.Chem_24_157
Author(s) : Zheng F , Zheng G , Deaciuc AG , Zhan CG , Dwoskin LP , Crooks PA
Ref : J Enzyme Inhib Med Chem , 24 :157 , 2009
PubMedID: 18629679

Title : Free-energy perturbation simulation on transition states and redesign of butyrylcholinesterase - Yang_2009_Biophys.J_96_1931
Author(s) : Yang W , Pan Y , Zheng F , Cho H , Tai HH , Zhan CG
Ref : Biophysical Journal , 96 :1931 , 2009
PubMedID: 19254552

Title : Modeling binding modes of alpha7 nicotinic acetylcholine receptor with ligands: the roles of Gln117 and other residues of the receptor in agonist binding - Huang_2008_J.Med.Chem_51_6293
Author(s) : Huang X , Zheng F , Stokes C , Papke RL , Zhan CG
Ref : Journal of Medicinal Chemistry , 51 :6293 , 2008
PubMedID: 18826295

Title : Structure-and-mechanism-based design and discovery of therapeutics for cocaine overdose and addiction - Zheng_2008_Org.Biomol.Chem_6_836
Author(s) : Zheng F , Zhan CG
Ref : Org Biomol Chem , 6 :836 , 2008
PubMedID: 18292872

Title : Rational design of an enzyme mutant for anti-cocaine therapeutics - Zheng_2008_J.Comput.Aided.Mol.Des_22_661
Author(s) : Zheng F , Zhan CG
Ref : J Comput Aided Mol Des , 22 :661 , 2008
PubMedID: 17989928

Title : Most efficient cocaine hydrolase designed by virtual screening of transition states - Zheng_2008_J.Am.Chem.Soc_130_12148
Author(s) : Zheng F , Yang W , Ko MC , Liu J , Cho H , Gao D , Tong M , Tai HH , Woods JH , Zhan CG
Ref : Journal of the American Chemical Society , 130 :12148 , 2008
PubMedID: 18710224

Title : Molecular cloning, and characterization of a modular acetyl xylan esterase from the edible straw mushroom Volvariella volvacea - Ding_2007_FEMS.Microbiol.Lett_274_304
Author(s) : Ding S , Cao J , Zhou R , Zheng F
Ref : FEMS Microbiology Letters , 274 :304 , 2007
PubMedID: 17623028

Title : Computational neural network analysis of the affinity of lobeline and tetrabenazine analogs for the vesicular monoamine transporter-2 - Zheng_2007_Bioorg.Med.Chem_15_2975
Author(s) : Zheng F , Zheng G , Deaciuc AG , Zhan CG , Dwoskin LP , Crooks PA
Ref : Bioorganic & Medicinal Chemistry , 15 :2975 , 2007
PubMedID: 17331733

Title : A glimpse of streptococcal toxic shock syndrome from comparative genomics of S. suis 2 Chinese isolates - Chen_2007_PLoS.One_2_e315
Author(s) : Chen C , Tang J , Dong W , Wang C , Feng Y , Wang J , Zheng F , Pan X , Liu D , Li M , Song Y , Zhu X , Sun H , Feng T , Guo Z , Ju A , Ge J , Dong Y , Sun W , Jiang Y , Yan J , Yang H , Wang X , Gao GF , Yang R , Yu J
Ref : PLoS ONE , 2 :e315 , 2007
PubMedID: 17375201
Gene_locus related to this paper: strsu-a4vws4 , strsu-q302y4 , strsy-a4vus4 , strsy-a4vwf6

Title : Modeling subtype-selective agonists binding with alpha4beta2 and alpha7 nicotinic acetylcholine receptors: effects of local binding and long-range electrostatic interactions - Huang_2006_J.Med.Chem_49_7661
Author(s) : Huang X , Zheng F , Chen X , Crooks PA , Dwoskin LP , Zhan CG
Ref : Journal of Medicinal Chemistry , 49 :7661 , 2006
PubMedID: 17181149

Title : QSAR modeling of mono- and bis-quaternary ammonium salts that act as antagonists at neuronal nicotinic acetylcholine receptors mediating dopamine release - Zheng_2006_Bioorg.Med.Chem_14_3017
Author(s) : Zheng F , Bayram E , Sumithran SP , Ayers JT , Zhan CG , Schmitt JD , Dwoskin LP , Crooks PA
Ref : Bioorganic & Medicinal Chemistry , 14 :3017 , 2006
PubMedID: 16431111

Title : Modeling multiple species of nicotine and deschloroepibatidine interacting with alpha4beta2 nicotinic acetylcholine receptor: from microscopic binding to phenomenological binding affinity - Huang_2005_J.Am.Chem.Soc_127_14401
Author(s) : Huang X , Zheng F , Crooks PA , Dwoskin LP , Zhan CG
Ref : Journal of the American Chemical Society , 127 :14401 , 2005
PubMedID: 16218635

Title : M2 muscarinic acetylcholine receptor knock-out mice show deficits in behavioral flexibility, working memory, and hippocampal plasticity - Seeger_2004_J.Neurosci_24_10117
Author(s) : Seeger T , Fedorova I , Zheng F , Miyakawa T , Koustova E , Gomeza J , Basile AS , Alzheimer C , Wess J
Ref : Journal of Neuroscience , 24 :10117 , 2004
PubMedID: 15537882

Title : Fundamental reaction mechanism for cocaine hydrolysis in human butyrylcholinesterase - Zhan_2003_J.Am.Chem.Soc_125_2462
Author(s) : Zhan CG , Zheng F , Landry DW
Ref : Journal of the American Chemical Society , 125 :2462 , 2003
PubMedID: 12603134