Leadlay PF

References (16)

Title : Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactones - Pidot_2008_BMC.Genomics_9_462
Author(s) : Pidot SJ , Hong H , Seemann T , Porter JL , Yip MJ , Men A , Johnson M , Wilson P , Davies JK , Leadlay PF , Stinear TP
Ref : BMC Genomics , 9 :462 , 2008
PubMedID: 18840298

Title : Insights into polyether biosynthesis from analysis of the nigericin biosynthetic gene cluster in Streptomyces sp. DSM4137 - Harvey_2007_Chem.Biol_14_703
Author(s) : Harvey BM , Mironenko T , Sun Y , Hong H , Deng Z , Leadlay PF , Weissman KJ , Haydock SF
Ref : Chemical Biology , 14 :703 , 2007
PubMedID: 17584617
Gene_locus related to this paper: strvo-q27w67

Title : Evidence that a novel thioesterase is responsible for polyketide chain release during biosynthesis of the polyether ionophore monensin - Harvey_2006_Chembiochem_7_1435
Author(s) : Harvey BM , Hong H , Jones MA , Hughes-Thomas ZA , Goss RM , Heathcote ML , Bolanos-Garcia VM , Kroutil W , Staunton J , Leadlay PF , Spencer JB
Ref : Chembiochem , 7 :1435 , 2006
PubMedID: 16897798
Gene_locus related to this paper: strci-MONCII

Title : Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449 - Haydock_2005_Microbiology_151_3161
Author(s) : Haydock SF , Appleyard AN , Mironenko T , Lester J , Scott N , Leadlay PF
Ref : Microbiology , 151 :3161 , 2005
PubMedID: 16207901
Gene_locus related to this paper: 9acto-q3s868 , 9acto-q3s880

Title : Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans - Stinear_2004_Proc.Natl.Acad.Sci.U.S.A_101_1345
Author(s) : Stinear TP , Mve-Obiang A , Small PL , Frigui W , Pryor MJ , Brosch R , Jenkin GA , Johnson PD , Davies JK , Lee RE , Adusumilli S , Garnier T , Haydock SF , Leadlay PF , Cole ST
Ref : Proc Natl Acad Sci U S A , 101 :1345 , 2004
PubMedID: 14736915

Title : Biosynthesis of the angiogenesis inhibitor borrelidin by Streptomyces parvulus Tu4055: cluster analysis and assignment of functions - Olano_2004_Chem.Biol_11_87
Author(s) : Olano C , Wilkinson B , Sanchez C , Moss SJ , Sheridan R , Math V , Weston AJ , Brana AF , Martin CJ , Oliynyk M , Mendez C , Leadlay PF , Salas JA
Ref : Chemical Biology , 11 :87 , 2004
PubMedID: 15112998
Gene_locus related to this paper: 9acto-q70hz7 , 9acto-q70i09 , 9acto-q70i12

Title : Biosynthetic gene cluster of the glycopeptide antibiotic teicoplanin: characterization of two glycosyltransferases and the key acyltransferase - Li_2004_Chem.Biol_11_107
Author(s) : Li TL , Huang F , Haydock SF , Mironenko T , Leadlay PF , Spencer JB
Ref : Chemical Biology , 11 :107 , 2004
PubMedID: 15113000
Gene_locus related to this paper: actti-q6zzg3 , actti-q6zzj3 , actti-q6zzg0

Title : Analysis of the biosynthetic gene cluster for the polyether antibiotic monensin in Streptomyces cinnamonensis and evidence for the role of monB and monC genes in oxidative cyclization - Oliynyk_2003_Mol.Microbiol_49_1179
Author(s) : Oliynyk M , Stark CB , Bhatt A , Jones MA , Hughes-Thomas ZA , Wilkinson C , Oliynyk Z , Demydchuk Y , Staunton J , Leadlay PF
Ref : Molecular Microbiology , 49 :1179 , 2003
PubMedID: 12940979
Gene_locus related to this paper: strci-MONAIX , strci-MONAX , strci-MONCII , strci-Q846W0

Title : Evidence from engineered gene fusions for the repeated use of a module in a modular polyketide synthase - Olano_2003_Chem.Commun.(Camb)__2780
Author(s) : Olano C , Wilkinson B , Moss SJ , Brana AF , Mendez C , Leadlay PF , Salas JA
Ref : Chem Commun (Camb) , :2780 , 2003
PubMedID: 14651102
Gene_locus related to this paper: 9acto-q70hz7 , 9acto-q70i09 , 9acto-q70i12

Title : Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase - Molnar_1996_Gene_169_1
Author(s) : Molnar I , Aparicio JF , Haydock SF , Khaw LE , Schwecke T , Konig A , Staunton J , Leadlay PF
Ref : Gene , 169 :1 , 1996
PubMedID: 8635730
Gene_locus related to this paper: strhy-ORFZ

Title : Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase - Aparicio_1996_Gene_169_9
Author(s) : Aparicio JF , Molnar I , Schwecke T , Konig A , Haydock SF , Khaw LE , Staunton J , Leadlay PF
Ref : Gene , 169 :9 , 1996
PubMedID: 8635756
Gene_locus related to this paper: strhy-ORFZ

Title : 6-Deoxyerythronolide-B synthase 2 from Saccharopolyspora erythraea. Cloning of the structural gene, sequence analysis and inferred domain structure of the multifunctional enzyme - Bevitt_1992_Eur.J.Biochem_204_39
Author(s) : Bevitt DJ , Cortes J , Haydock SF , Leadlay PF
Ref : European Journal of Biochemistry , 204 :39 , 1992
PubMedID: 1740151
Gene_locus related to this paper: sacer-ery3

Title : Identification of DEBS 1, DEBS 2 and DEBS 3, the multienzyme polypeptides of the erythromycin-producing polyketide synthase from Saccharopolyspora erythraea - Caffrey_1992_FEBS.Lett_304_225
Author(s) : Caffrey P , Bevitt DJ , Staunton J , Leadlay PF
Ref : FEBS Letters , 304 :225 , 1992
PubMedID: 1618327
Gene_locus related to this paper: sacer-ery3

Title : Cloning and sequence analysis of genes involved in erythromycin biosynthesis in Saccharopolyspora erythraea: sequence similarities between EryG and a family of S-adenosylmethionine-dependent methyltransferases. -
Author(s) : Haydock SF , Dowson JA , Dhillon N , Roberts GA , Cortes J , Leadlay PF
Ref : Molecular & General Genetics , 230 :120 , 1991
PubMedID: 1840640
Gene_locus related to this paper: sacer-Q9JN61

Title : An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of Saccharopolyspora erythraea - Cortes_1990_Nature_348_176
Author(s) : Cortes J , Haydock SF , Roberts GA , Bevitt DJ , Leadlay PF
Ref : Nature , 348 :176 , 1990
PubMedID: 2234082
Gene_locus related to this paper: sacer-ery3