Title : Donepezil-induced Degradation of hERG Potassium Channel via Lysosomal Pathway is Exacerbated by Hypoxia - Li_2025_Eur.J.Pharmacol__177549 |
Author(s) : Li YX , Sun JY , Li XX , Yu WT , Ren JC , Wang BQ , Han XX , Ma L , Sun X , Teng W , Gu XW , Ding QR , Li BX |
Ref : European Journal of Pharmacology , :177549 , 2025 |
Abstract : |
PubMedSearch : Li_2025_Eur.J.Pharmacol__177549 |
PubMedID: 40157707 |
Title : Lipases are differentially regulated by hormones to maintain free fatty acid homeostasis for insect brain development - Li_2024_BMC.Biol_22_171 |
Author(s) : Li YX , Yan Q , Liu TW , Wang JX , Zhao XF |
Ref : BMC Biol , 22 :171 , 2024 |
Abstract : |
PubMedSearch : Li_2024_BMC.Biol_22_171 |
PubMedID: 39135168 |
Gene_locus related to this paper: helam-a0a2w1bfr0 , helam-Lhalike |
Title : Discovery and synthesis of tetrahydropyrimidinedione-4-carboxamides as endothelial lipase inhibitors - Hu_2018_Bioorg.Med.Chem.Lett_28_3721 |
Author(s) : Hu CH , Wang TC , Qiao JX , Haque L , Chen AYA , Taylor DS , Ying X , Onorato JM , Galella M , Shen H , Huang CS , Toussaint N , Li YX , Abell L , Adam LP , Gordon D , Wexler RR , Finlay HJ |
Ref : Bioorganic & Medicinal Chemistry Lett , 28 :3721 , 2018 |
Abstract : |
PubMedSearch : Hu_2018_Bioorg.Med.Chem.Lett_28_3721 |
PubMedID: 30348490 |
Title : Optimization of Activity, Selectivity, and Liability Profiles in 5-Oxopyrrolopyridine DPP4 Inhibitors Leading to Clinical Candidate (Sa)-2-(3-(Aminomethyl)-4-(2,4-dichlorophenyl)-2-methyl-5-oxo-5H-pyrrolo[3,4-b]py ridin-6(7H)-yl)-N,N-dimethylacetamide (BMS-767778) - Devasthale_2013_J.Med.Chem_56_7343 |
Author(s) : Devasthale P , Wang Y , Wang W , Fevig J , Feng J , Wang A , Harrity T , Egan D , Morgan N , Cap M , Fura A , Klei HE , Kish K , Weigelt C , Sun L , Levesque P , Moulin F , Li YX , Zahler R , Kirby MS , Hamann LG |
Ref : Journal of Medicinal Chemistry , 56 :7343 , 2013 |
Abstract : |
PubMedSearch : Devasthale_2013_J.Med.Chem_56_7343 |
PubMedID: 23964740 |
Gene_locus related to this paper: human-DPP4 |
Title : 7-Oxopyrrolopyridine-derived DPP4 inhibitors-mitigation of CYP and hERG liabilities via introduction of polar functionalities in the active site - Wang_2011_Bioorg.Med.Chem.Lett_21_6646 |
Author(s) : Wang W , Devasthale P , Wang A , Harrity T , Egan D , Morgan N , Cap M , Fura A , Klei HE , Kish K , Weigelt C , Sun L , Levesque P , Li YX , Zahler R , Kirby MS , Hamann LG |
Ref : Bioorganic & Medicinal Chemistry Lett , 21 :6646 , 2011 |
Abstract : |
PubMedSearch : Wang_2011_Bioorg.Med.Chem.Lett_21_6646 |
PubMedID: 21996520 |
Gene_locus related to this paper: human-DPP4 |
Title : Simple determination of huperzine A in human plasma by liquid chromatographic-tandem mass spectrometric method - Li_2007_Biomed.Chromatogr_21_15 |
Author(s) : Li YX , Jiang XH , Lan K , Wang L |
Ref : Biomedical Chromatography , 21 :15 , 2007 |
Abstract : |
PubMedSearch : Li_2007_Biomed.Chromatogr_21_15 |
PubMedID: 17080497 |
Title : Double-stranded RNA injection produces null phenotypes in zebrafish - Li_2000_Dev.Biol_217_394 |
Author(s) : Li YX , Farrell MJ , Liu R , Mohanty N , Kirby ML |
Ref : Developmental Biology , 217 :394 , 2000 |
Abstract : |
PubMedSearch : Li_2000_Dev.Biol_217_394 |
PubMedID: 10625563 |