| Title : Discovery of 4-(5-methyloxazolo[4,5-b]pyridin-2-yl)-1,4-diazabicyclo[3.2.2]nonane (CP-810,123), a novel alpha 7 nicotinic acetylcholine receptor agonist for the treatment of cognitive disorders in schizophrenia: synthesis, SAR development, and in vivo efficacy in cognition models - O'Donnell_2010_J.Med.Chem_53_1222 |
| Author(s) : O'Donnell CJ , Rogers BN , Bronk BS , Bryce DK , Coe JW , Cook KK , Duplantier AJ , Evrard E , Hajos M , Hoffmann WE , Hurst RS , Maklad N , Mather RJ , McLean S , Nedza FM , O'Neill BT , Peng L , Qian W , Rottas MM , Sands SB , Schmidt AW , Shrikhande AV , Spracklin DK , Wong DF , Zhang A , Zhang L |
| Ref : Journal of Medicinal Chemistry , 53 :1222 , 2010 |
| Abstract : |
| PubMedSearch : O'Donnell_2010_J.Med.Chem_53_1222 |
| PubMedID: 20043678 |
| Title : Discovery of 4-(5-methyloxazolo[4,5-b]pyridin-2-yl)-1,4-diazabicyclo[3.2.2]nonane (CP-810,123), a novel alpha 7 nicotinic acetylcholine receptor agonist for the treatment of cognitive disorders in schizophrenia: synthesis, SAR development, and in vivo efficacy in cognition models - O'Donnell_2010_J.Med.Chem_53_1222 |
| Author(s) : O'Donnell CJ , Rogers BN , Bronk BS , Bryce DK , Coe JW , Cook KK , Duplantier AJ , Evrard E , Hajos M , Hoffmann WE , Hurst RS , Maklad N , Mather RJ , McLean S , Nedza FM , O'Neill BT , Peng L , Qian W , Rottas MM , Sands SB , Schmidt AW , Shrikhande AV , Spracklin DK , Wong DF , Zhang A , Zhang L |
| Ref : Journal of Medicinal Chemistry , 53 :1222 , 2010 |
| Abstract : |
| PubMedSearch : O'Donnell_2010_J.Med.Chem_53_1222 |
| PubMedID: 20043678 |
| Title : Discovery of 4-(5-methyloxazolo[4,5-b]pyridin-2-yl)-1,4-diazabicyclo[3.2.2]nonane (CP-810,123), a novel alpha 7 nicotinic acetylcholine receptor agonist for the treatment of cognitive disorders in schizophrenia: synthesis, SAR development, and in vivo efficacy in cognition models - O'Donnell_2010_J.Med.Chem_53_1222 |
| Author(s) : O'Donnell CJ , Rogers BN , Bronk BS , Bryce DK , Coe JW , Cook KK , Duplantier AJ , Evrard E , Hajos M , Hoffmann WE , Hurst RS , Maklad N , Mather RJ , McLean S , Nedza FM , O'Neill BT , Peng L , Qian W , Rottas MM , Sands SB , Schmidt AW , Shrikhande AV , Spracklin DK , Wong DF , Zhang A , Zhang L |
| Ref : Journal of Medicinal Chemistry , 53 :1222 , 2010 |
| Abstract : |
| PubMedSearch : O'Donnell_2010_J.Med.Chem_53_1222 |
| PubMedID: 20043678 |
| Title : Preclinical pharmacology of the alpha4beta2 nAChR partial agonist varenicline related to effects on reward, mood and cognition - Rollema_2009_Biochem.Pharmacol_78(7)_813 |
| Author(s) : Rollema H , Hajos M , Seymour PA , Kozak R , Majchrzak MJ , Guanowsky V , Horner WE , Chapin DS , Hoffmann WE , Johnson DE , McLean S , Freeman J , Williams KE |
| Ref : Biochemical Pharmacology , 78 :813 , 2009 |
| Abstract : |
| PubMedSearch : Rollema_2009_Biochem.Pharmacol_78(7)_813 |
| PubMedID: 19501054 |
| Title : Preclinical pharmacology of the alpha4beta2 nAChR partial agonist varenicline related to effects on reward, mood and cognition - Rollema_2009_Biochem.Pharmacol_78(7)_813 |
| Author(s) : Rollema H , Hajos M , Seymour PA , Kozak R , Majchrzak MJ , Guanowsky V , Horner WE , Chapin DS , Hoffmann WE , Johnson DE , McLean S , Freeman J , Williams KE |
| Ref : Biochemical Pharmacology , 78 :813 , 2009 |
| Abstract : |
| PubMedSearch : Rollema_2009_Biochem.Pharmacol_78(7)_813 |
| PubMedID: 19501054 |
| Title : Preclinical pharmacology of the alpha4beta2 nAChR partial agonist varenicline related to effects on reward, mood and cognition - Rollema_2009_Biochem.Pharmacol_78(7)_813 |
| Author(s) : Rollema H , Hajos M , Seymour PA , Kozak R , Majchrzak MJ , Guanowsky V , Horner WE , Chapin DS , Hoffmann WE , Johnson DE , McLean S , Freeman J , Williams KE |
| Ref : Biochemical Pharmacology , 78 :813 , 2009 |
| Abstract : |
| PubMedSearch : Rollema_2009_Biochem.Pharmacol_78(7)_813 |
| PubMedID: 19501054 |