Hajos M

General

Full name : Hajos Mihaly

First name : Mihaly

Mail : University Dept. of Pharmacology, Mansfield Road, Oxford OXl 3QT

Zip Code :

City :

Country : United Kingdom

Email :

Phone : (44) 865 271850

Fax : (44) 865 271853

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References (13)

Title : Treatment effects on event-related EEG potentials and oscillations in Alzheimer's disease - Yener_2022_Int.J.Psychophysiol__
Author(s) : Yener G , Hunerli-Gunduz D , Yildirim E , Akturk T , Basar-Eroglu C , Bonanni L , Del Percio C , Farina F , Ferri R , Guntekin B , Hajos M , Ibanez A , Jiang Y , Lizio R , Lopez S , Noce G , Parra M , Randall F , Stocchi F , Babiloni C
Ref : Int J Psychophysiol , : , 2022
Abstract :
PubMedSearch : Yener_2022_Int.J.Psychophysiol__
PubMedID: 35588964

Title : Modulation of hippocampal neuronal network oscillations by alpha7 nACh receptors - Stoiljkovic_2015_Biochem.Pharmacol_97(4)_445
Author(s) : Stoiljkovic M , Kelley C , Nagy D , Hajos M
Ref : Biochemical Pharmacology , 97 :445 , 2015
Abstract :
PubMedSearch : Stoiljkovic_2015_Biochem.Pharmacol_97(4)_445
PubMedID: 26206189

Title : Concentration-response relationship of the alpha7 nicotinic acetylcholine receptor agonist FRM-17874 across multiple in vitro and in vivo assays - Stoiljkovic_2015_Biochem.Pharmacol_97(4)_576
Author(s) : Stoiljkovic M , Leventhal L , Chen A , Chen T , Driscoll R , Flood D , Hodgdon H , Hurst R , Nagy D , Piser T , Tang C , Townsend M , Tu Z , Bertrand D , Koenig G , Hajos M
Ref : Biochemical Pharmacology , 97 :576 , 2015
Abstract :
PubMedSearch : Stoiljkovic_2015_Biochem.Pharmacol_97(4)_576
PubMedID: 26206187

Title : Targeting alpha7 nicotinic acetylcholine receptors in the treatment of schizophrenia - Hajos_2010_Curr.Pharm.Des_16_538
Author(s) : Hajos M , Rogers BN
Ref : Curr Pharm Des , 16 :538 , 2010
Abstract :
PubMedSearch : Hajos_2010_Curr.Pharm.Des_16_538
PubMedID: 19909231

Title : Discovery of 4-(5-methyloxazolo[4,5-b]pyridin-2-yl)-1,4-diazabicyclo[3.2.2]nonane (CP-810,123), a novel alpha 7 nicotinic acetylcholine receptor agonist for the treatment of cognitive disorders in schizophrenia: synthesis, SAR development, and in vivo efficacy in cognition models - O'Donnell_2010_J.Med.Chem_53_1222
Author(s) : O'Donnell CJ , Rogers BN , Bronk BS , Bryce DK , Coe JW , Cook KK , Duplantier AJ , Evrard E , Hajos M , Hoffmann WE , Hurst RS , Maklad N , Mather RJ , McLean S , Nedza FM , O'Neill BT , Peng L , Qian W , Rottas MM , Sands SB , Schmidt AW , Shrikhande AV , Spracklin DK , Wong DF , Zhang A , Zhang L
Ref : Journal of Medicinal Chemistry , 53 :1222 , 2010
Abstract :
PubMedSearch : O'Donnell_2010_J.Med.Chem_53_1222
PubMedID: 20043678

Title : Preclinical pharmacology of the alpha4beta2 nAChR partial agonist varenicline related to effects on reward, mood and cognition - Rollema_2009_Biochem.Pharmacol_78(7)_813
Author(s) : Rollema H , Hajos M , Seymour PA , Kozak R , Majchrzak MJ , Guanowsky V , Horner WE , Chapin DS , Hoffmann WE , Johnson DE , McLean S , Freeman J , Williams KE
Ref : Biochemical Pharmacology , 78 :813 , 2009
Abstract :
PubMedSearch : Rollema_2009_Biochem.Pharmacol_78(7)_813
PubMedID: 19501054

Title : Discovery of N-[(3R,5R)-1-azabicyclo[3.2.1]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide as an agonist of the alpha7 nicotinic acetylcholine receptor: in vitro and in vivo activity - Acker_2008_Bioorg.Med.Chem.Lett_18_3611
Author(s) : Acker BA , Jacobsen EJ , Rogers BN , Wishka DG , Reitz SC , Piotrowski DW , Myers JK , Wolfe ML , Groppi VE , Thornburgh BA , Tinholt PM , Walters RR , Olson BA , Fitzgerald L , Staton BA , Raub TJ , Krause M , Li KS , Hoffmann WE , Hajos M , Hurst RS , Walker DP
Ref : Bioorganic & Medicinal Chemistry Lett , 18 :3611 , 2008
Abstract :
PubMedSearch : Acker_2008_Bioorg.Med.Chem.Lett_18_3611
PubMedID: 18490160

Title : Design, synthesis, structure-activity relationship, and in vivo activity of azabicyclic aryl amides as alpha7 nicotinic acetylcholine receptor agonists - Walker_2006_Bioorg.Med.Chem_14_8219
Author(s) : Walker DP , Wishka DG , Piotrowski DW , Jia S , Reitz SC , Yates KM , Myers JK , Vetman TN , Margolis BJ , Jacobsen EJ , Acker BA , Groppi VE , Wolfe ML , Thornburgh BA , Tinholt PM , Cortes-Burgos LA , Walters RR , Hester MR , Seest EP , Dolak LA , Han F , Olson BA , Fitzgerald L , Staton BA , Raub TJ , Hajos M , Hoffmann WE , Li KS , Higdon NR , Wall TM , Hurst RS , Wong EH , Rogers BN
Ref : Bioorganic & Medicinal Chemistry , 14 :8219 , 2006
Abstract :
PubMedSearch : Walker_2006_Bioorg.Med.Chem_14_8219
PubMedID: 17011782

Title : Discovery of N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide, an agonist of the alpha7 nicotinic acetylcholine receptor, for the potential treatment of cognitive deficits in schizophrenia: synthesis and structure--activity relationship - Wishka_2006_J.Med.Chem_49_4425
Author(s) : Wishka DG , Walker DP , Yates KM , Reitz SC , Jia S , Myers JK , Olson KL , Jacobsen EJ , Wolfe ML , Groppi VE , Hanchar AJ , Thornburgh BA , Cortes-Burgos LA , Wong EH , Staton BA , Raub TJ , Higdon NR , Wall TM , Hurst RS , Walters RR , Hoffmann WE , Hajos M , Franklin S , Carey G , Gold LH , Cook KK , Sands SB , Zhao SX , Soglia JR , Kalgutkar AS , Arneric SP , Rogers BN
Ref : Journal of Medicinal Chemistry , 49 :4425 , 2006
Abstract :
PubMedSearch : Wishka_2006_J.Med.Chem_49_4425
PubMedID: 16821801

Title : A novel positive allosteric modulator of the alpha7 neuronal nicotinic acetylcholine receptor: in vitro and in vivo characterization - Hurst_2005_J.Neurosci_25_4396
Author(s) : Hurst RS , Hajos M , Raggenbass M , Wall TM , Higdon NR , Lawson JA , Rutherford-Root KL , Berkenpas MB , Hoffmann WE , Piotrowski DW , Groppi VE , Allaman G , Ogier R , Bertrand S , Bertrand D , Arneric SP
Ref : Journal of Neuroscience , 25 :4396 , 2005
Abstract :
PubMedSearch : Hurst_2005_J.Neurosci_25_4396
PubMedID: 15858066

Title : Discovery and structure-activity relationship of quinuclidine benzamides as agonists of alpha7 nicotinic acetylcholine receptors - Bodnar_2005_J.Med.Chem_48_905
Author(s) : Bodnar AL , Cortes-Burgos LA , Cook KK , Dinh DM , Groppi VE , Hajos M , Higdon NR , Hoffmann WE , Hurst RS , Myers JK , Rogers BN , Wall TM , Wolfe ML , Wong E
Ref : Journal of Medicinal Chemistry , 48 :905 , 2005
Abstract :
PubMedSearch : Bodnar_2005_J.Med.Chem_48_905
PubMedID: 15715459

Title : Nicotine inhibits firing activity of dorsal raphe 5-HT neurones in vivo - Engberg_2000_Naunyn.Schmiedebergs.Arch.Pharmacol_362_41
Author(s) : Engberg G , Erhardt S , Sharp T , Hajos M
Ref : Naunyn Schmiedebergs Arch Pharmacol , 362 :41 , 2000
Abstract :
PubMedSearch : Engberg_2000_Naunyn.Schmiedebergs.Arch.Pharmacol_362_41
PubMedID: 10935531

Title : Differential actions of acetylcholinesterase on the soma and dendrites of dopaminergic substantia nigra neurons in vitro - Hajos_1992_Brain.Res_585_416
Author(s) : Hajos M , Greenfield SA
Ref : Brain Research , 585 :416 , 1992
Abstract :
PubMedSearch : Hajos_1992_Brain.Res_585_416
PubMedID: 1511329