Full name : Rogers Bruce N
First name : Bruce N
Mail : Pfizer Inc., Eastern Point Road, Groton, CT 06340
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Comment
| Title : Discovery of Trifluoromethyl Glycol Carbamates as Potent and Selective Covalent Monoacylglycerol Lipase (MAGL) Inhibitors for Treatment of Neuroinflammation - McAllister_2018_J.Med.Chem_61_3008 |
| Author(s) : McAllister LA , Butler CR , Mente S , O'Neil SV , Fonseca KR , Piro JR , Cianfrogna JA , Foley TL , Gilbert AM , Harris AR , Helal CJ , Johnson DS , Montgomery JI , Nason DM , Noell S , Pandit J , Rogers BN , Samad TA , Shaffer CL , da Silva RG , Uccello DP , Webb D , Brodney MA |
| Ref : Journal of Medicinal Chemistry , 61 :3008 , 2018 |
| Abstract : |
| PubMedSearch : McAllister_2018_J.Med.Chem_61_3008 |
| PubMedID: 29498843 |
| Gene_locus related to this paper: human-MGLL |
| Title : Azetidine and Piperidine Carbamates as Efficient, Covalent Inhibitors of Monoacylglycerol Lipase - Butler_2017_J.Med.Chem_60_9860 |
| Author(s) : Butler CR , Beck EM , Harris A , Huang Z , McAllister LA , Am Ende CW , Fennell K , Foley TL , Fonseca K , Hawrylik SJ , Johnson DS , Knafels JD , Mente S , Noell GS , Pandit J , Phillips TB , Piro JR , Rogers BN , Samad TA , Wang J , Wan S , Brodney MA |
| Ref : Journal of Medicinal Chemistry , 60 :9860 , 2017 |
| Abstract : |
| PubMedSearch : Butler_2017_J.Med.Chem_60_9860 |
| PubMedID: 29148769 |
| Gene_locus related to this paper: human-MGLL |
| Title : Affinity purification of a chimeric nicotinic acetylcholine receptor in the agonist and antagonist bound states - Liu_2011_Protein.Expr.Purif_79_102 |
| Author(s) : Liu S , Babcock MS , Bode J , Chang JS , Fischer HD , Garlick RL , Gill GS , Lund ET , Margolis BJ , Mathews WR , Rogers BN , Wolfe M , Groppi V , Baldwin ET |
| Ref : Protein Expr Purif , 79 :102 , 2011 |
| Abstract : |
| PubMedSearch : Liu_2011_Protein.Expr.Purif_79_102 |
| PubMedID: 21664975 |
| Title : Discovery of 4-(5-methyloxazolo[4,5-b]pyridin-2-yl)-1,4-diazabicyclo[3.2.2]nonane (CP-810,123), a novel alpha 7 nicotinic acetylcholine receptor agonist for the treatment of cognitive disorders in schizophrenia: synthesis, SAR development, and in vivo efficacy in cognition models - O'Donnell_2010_J.Med.Chem_53_1222 |
| Author(s) : O'Donnell CJ , Rogers BN , Bronk BS , Bryce DK , Coe JW , Cook KK , Duplantier AJ , Evrard E , Hajos M , Hoffmann WE , Hurst RS , Maklad N , Mather RJ , McLean S , Nedza FM , O'Neill BT , Peng L , Qian W , Rottas MM , Sands SB , Schmidt AW , Shrikhande AV , Spracklin DK , Wong DF , Zhang A , Zhang L |
| Ref : Journal of Medicinal Chemistry , 53 :1222 , 2010 |
| Abstract : |
| PubMedSearch : O'Donnell_2010_J.Med.Chem_53_1222 |
| PubMedID: 20043678 |
| Title : Targeting alpha7 nicotinic acetylcholine receptors in the treatment of schizophrenia - Hajos_2010_Curr.Pharm.Des_16_538 |
| Author(s) : Hajos M , Rogers BN |
| Ref : Curr Pharm Des , 16 :538 , 2010 |
| Abstract : |
| PubMedSearch : Hajos_2010_Curr.Pharm.Des_16_538 |
| PubMedID: 19909231 |
| Title : Discovery of N-[(3R,5R)-1-azabicyclo[3.2.1]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide as an agonist of the alpha7 nicotinic acetylcholine receptor: in vitro and in vivo activity - Acker_2008_Bioorg.Med.Chem.Lett_18_3611 |
| Author(s) : Acker BA , Jacobsen EJ , Rogers BN , Wishka DG , Reitz SC , Piotrowski DW , Myers JK , Wolfe ML , Groppi VE , Thornburgh BA , Tinholt PM , Walters RR , Olson BA , Fitzgerald L , Staton BA , Raub TJ , Krause M , Li KS , Hoffmann WE , Hajos M , Hurst RS , Walker DP |
| Ref : Bioorganic & Medicinal Chemistry Lett , 18 :3611 , 2008 |
| Abstract : |
| PubMedSearch : Acker_2008_Bioorg.Med.Chem.Lett_18_3611 |
| PubMedID: 18490160 |
| Title : Design, synthesis, structure-activity relationship, and in vivo activity of azabicyclic aryl amides as alpha7 nicotinic acetylcholine receptor agonists - Walker_2006_Bioorg.Med.Chem_14_8219 |
| Author(s) : Walker DP , Wishka DG , Piotrowski DW , Jia S , Reitz SC , Yates KM , Myers JK , Vetman TN , Margolis BJ , Jacobsen EJ , Acker BA , Groppi VE , Wolfe ML , Thornburgh BA , Tinholt PM , Cortes-Burgos LA , Walters RR , Hester MR , Seest EP , Dolak LA , Han F , Olson BA , Fitzgerald L , Staton BA , Raub TJ , Hajos M , Hoffmann WE , Li KS , Higdon NR , Wall TM , Hurst RS , Wong EH , Rogers BN |
| Ref : Bioorganic & Medicinal Chemistry , 14 :8219 , 2006 |
| Abstract : |
| PubMedSearch : Walker_2006_Bioorg.Med.Chem_14_8219 |
| PubMedID: 17011782 |
| Title : Discovery of N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide, an agonist of the alpha7 nicotinic acetylcholine receptor, for the potential treatment of cognitive deficits in schizophrenia: synthesis and structure--activity relationship - Wishka_2006_J.Med.Chem_49_4425 |
| Author(s) : Wishka DG , Walker DP , Yates KM , Reitz SC , Jia S , Myers JK , Olson KL , Jacobsen EJ , Wolfe ML , Groppi VE , Hanchar AJ , Thornburgh BA , Cortes-Burgos LA , Wong EH , Staton BA , Raub TJ , Higdon NR , Wall TM , Hurst RS , Walters RR , Hoffmann WE , Hajos M , Franklin S , Carey G , Gold LH , Cook KK , Sands SB , Zhao SX , Soglia JR , Kalgutkar AS , Arneric SP , Rogers BN |
| Ref : Journal of Medicinal Chemistry , 49 :4425 , 2006 |
| Abstract : |
| PubMedSearch : Wishka_2006_J.Med.Chem_49_4425 |
| PubMedID: 16821801 |
| Title : Discovery and structure-activity relationship of quinuclidine benzamides as agonists of alpha7 nicotinic acetylcholine receptors - Bodnar_2005_J.Med.Chem_48_905 |
| Author(s) : Bodnar AL , Cortes-Burgos LA , Cook KK , Dinh DM , Groppi VE , Hajos M , Higdon NR , Hoffmann WE , Hurst RS , Myers JK , Rogers BN , Wall TM , Wolfe ML , Wong E |
| Ref : Journal of Medicinal Chemistry , 48 :905 , 2005 |
| Abstract : |
| PubMedSearch : Bodnar_2005_J.Med.Chem_48_905 |
| PubMedID: 15715459 |