| Title : Common single-base insertions in the VNTR of the carboxyl ester lipase (CEL) gene are benign and also likely to arise somatically in the exocrine pancreas - Brekke_2024_Hum.Mol.Genet__ |
| Author(s) : Brekke RS , Gravdal A , El Jellas K , Curry GE , Lin J , Wilhelm SJ , Steine SJ , Mas E , Johansson S , Lowe ME , Johansson BB , Xiao X , Fjeld K , Molven A |
| Ref : Hum Mol Genet , : , 2024 |
| Abstract : |
| PubMedSearch : Brekke_2024_Hum.Mol.Genet__ |
| PubMedID: 38483348 |
| Title : Abnormal exocrine-endocrine cell cross-talk promotes beta-cell dysfunction and loss in MODY8 - Kahraman_2022_Nat.Metab_4_76 |
| Author(s) : Kahraman S , Dirice E , Basile G , Diegisser D , Alam J , Johansson BB , Gupta MK , Hu J , Huang L , Soh CL , Huangfu D , Muthuswamy SK , Raeder H , Molven A , Kulkarni RN |
| Ref : Nat Metab , 4 :76 , 2022 |
| Abstract : |
| PubMedSearch : Kahraman_2022_Nat.Metab_4_76 |
| PubMedID: 35058633 |
| Gene_locus related to this paper: human-CEL |
| Title : The genetic risk factor CEL-HYB1 causes proteotoxicity and chronic pancreatitis in mice - Fjeld_2022_Pancreatology_22_1099 |
| Author(s) : Fjeld K , Gravdal A , Brekke RS , Alam J , Wilhelm SJ , El Jellas K , Pettersen HN , Lin J , Solheim MH , Steine SJ , Johansson BB , Njlstad PR , Verbeke CS , Xiao X , Lowe ME , Molven A |
| Ref : Pancreatology , 22 :1099 , 2022 |
| Abstract : |
| PubMedSearch : Fjeld_2022_Pancreatology_22_1099 |
| PubMedID: 36379850 |
| Gene_locus related to this paper: human-CEL |
| Title : Protein misfolding in combination with other risk factors in CEL-HYB1-mediated chronic pancreatitis - Tjora_2021_Eur.J.Gastroenterol.Hepatol_33_839 |
| Author(s) : Tjora E , Gravdal A , Engjom T , Cnop M , Johansson BB , Dimcevski GG , Molven A , Fjeld K |
| Ref : European Journal of Gastroenterology & Hepatology , 33 :839 , 2021 |
| Abstract : |
| PubMedSearch : Tjora_2021_Eur.J.Gastroenterol.Hepatol_33_839 |
| PubMedID: 33079780 |
| Gene_locus related to this paper: human-CEL |
| Title : The position of single-base deletions in the VNTR sequence of the carboxyl ester lipase (CEL) gene determines proteotoxicity - Gravdal_2021_J.Biol.Chem_296_100661 |
| Author(s) : Gravdal A , Xiao X , Cnop M , El Jellas K , Johansson S , Njolstad PR , Lowe ME , Johansson BB , Molven A , Fjeld K |
| Ref : Journal of Biological Chemistry , 296 :100661 , 2021 |
| Abstract : |
| PubMedSearch : Gravdal_2021_J.Biol.Chem_296_100661 |
| PubMedID: 33862081 |
| Title : Two new mutations in the CEL gene causing diabetes and hereditary pancreatitis: How to correctly identify MODY8 cases - El Jellas_2021_J.Clin.Endocrinol.Metab__ |
| Author(s) : El Jellas K , Dusatkova P , Haldorsen IS , Molnes J , Tjora E , Johansson BB , Fjeld K , Johansson S , Pruhova S , Groop L , Lohr JM , Njolstad PR , Molven A |
| Ref : J Clinical Endocrinology Metab , : , 2021 |
| Abstract : |
| PubMedSearch : El Jellas_2021_J.Clin.Endocrinol.Metab__ |
| PubMedID: 34850019 |
| Gene_locus related to this paper: human-CEL |
| Title : Characterization of CEL-DUP2: Complete duplication of the carboxyl ester lipase gene is unlikely to influence risk of chronic pancreatitis - Fjeld_2020_Pancreatology__ |
| Author(s) : Fjeld K , Masson E , Lin JH , Michl P , Stokowy T , Gravdal A , El Jellas K , Steine SJ , Hoem D , Johansson BB , Dalva M , Ruffert C , Zou WB , Li ZS , Njolstad PR , Chen JM , Liao Z , Johansson S , Rosendahl J , Ferec C , Molven A |
| Ref : Pancreatology , : , 2020 |
| Abstract : |
| PubMedSearch : Fjeld_2020_Pancreatology__ |
| PubMedID: 32007358 |
| Title : Single nucleotide polymorphisms in CEL-HYB1 increase risk for chronic pancreatitis through proteotoxic misfolding - Cassidy_2020_Hum.Mutat_41_1967 |
| Author(s) : Cassidy BM , Zino S , Fjeld K , Molven A , Lowe ME , Xiao X |
| Ref : Hum Mutat , 41 :1967 , 2020 |
| Abstract : |
| PubMedSearch : Cassidy_2020_Hum.Mutat_41_1967 |
| PubMedID: 32906201 |
| Gene_locus related to this paper: human-CEL |
| Title : Pathogenic Carboxyl Ester Lipase (CEL) Variants Interact with the Normal CEL Protein in Pancreatic Cells - Dalva_2020_Cells_9_244 |
| Author(s) : Dalva M , Lavik IK , El Jellas K , Gravdal A , Lugea A , Pandol SJ , Njolstad PR , Waldron RT , Fjeld K , Johansson BB , Molven A |
| Ref : Cells , 9 :244 , 2020 |
| Abstract : |
| PubMedSearch : Dalva_2020_Cells_9_244 |
| PubMedID: 31963687 |
| Gene_locus related to this paper: human-CEL |
| Title : The hybrid allele 1 of carboxyl-ester lipase (CEL-HYB1) in Polish pediatric patients with chronic pancreatitis - Oracz_2019_Pancreatology_19_531 |
| Author(s) : Oracz G , Kujko AA , Fjeld K , Wertheim-Tysarowska K , Adamus-Bialek W , Steine SJ , Koziel D , Gluszek S , Molven A , Rygiel AM |
| Ref : Pancreatology , 19 :531 , 2019 |
| Abstract : |
| PubMedSearch : Oracz_2019_Pancreatology_19_531 |
| PubMedID: 31036489 |
| Title : The role of the carboxyl ester lipase (CEL) gene in pancreatic disease - Johansson_2018_Pancreatology_18_12 |
| Author(s) : Johansson BB , Fjeld K , El Jellas K , Gravdal A , Dalva M , Tjora E , Raeder H , Kulkarni RN , Johansson S , Njolstad PR , Molven A |
| Ref : Pancreatology , 18 :12 , 2018 |
| Abstract : |
| PubMedSearch : Johansson_2018_Pancreatology_18_12 |
| PubMedID: 29233499 |
| Gene_locus related to this paper: human-CEL |
| Title : Copy number variants and VNTR length polymorphisms of the carboxyl-ester lipase (CEL) gene as risk factors in pancreatic cancer - Dalva_2017_Pancreatology_17_83 |
| Author(s) : Dalva M , El Jellas K , Steine SJ , Johansson BB , Ringdal M , Torsvik J , Immervoll H , Hoem D , Laemmerhirt F , Simon P , Lerch MM , Johansson S , Njolstad PR , Weiss FU , Fjeld K , Molven A |
| Ref : Pancreatology , 17 :83 , 2017 |
| Abstract : |
| PubMedSearch : Dalva_2017_Pancreatology_17_83 |
| PubMedID: 27773618 |
| Gene_locus related to this paper: human-CEL |
| Title : Branched Fatty Acid Esters of Hydroxy Fatty Acids Are Preferred Substrates of the MODY8 Protein Carboxyl Ester Lipase - Kolar_2016_Biochemistry_55_4636 |
| Author(s) : Kolar MJ , Kamat SS , Parsons WH , Homan EA , Maher T , Peroni OD , Syed I , Fjeld K , Molven A , Kahn BB , Cravatt BF , Saghatelian A |
| Ref : Biochemistry , 55 :4636 , 2016 |
| Abstract : |
| PubMedSearch : Kolar_2016_Biochemistry_55_4636 |
| PubMedID: 27509211 |
| Gene_locus related to this paper: human-CEL |
| Title : Lipase gene fusion: a new route to chronic pancreatitis - |
| Author(s) : Molven A , Njolstad PR , Weiss FU |
| Ref : Oncotarget , 6 :30443 , 2015 |
| PubMedID: 26387137 |
| Title : A recombined allele of the lipase gene CEL and its pseudogene CELP confers susceptibility to chronic pancreatitis - Fjeld_2015_Nat.Genet_47_518 |
| Author(s) : Fjeld K , Weiss FU , Lasher D , Rosendahl J , Chen JM , Johansson BB , Kirsten H , Ruffert C , Masson E , Steine SJ , Bugert P , Cnop M , Grutzmann R , Mayerle J , Mossner J , Ringdal M , Schulz HU , Sendler M , Simon P , Sztromwasser P , Torsvik J , Scholz M , Tjora E , Ferec C , Witt H , Lerch MM , Njolstad PR , Johansson S , Molven A |
| Ref : Nat Genet , 47 :518 , 2015 |
| Abstract : |
| PubMedSearch : Fjeld_2015_Nat.Genet_47_518 |
| PubMedID: 25774637 |
| Gene_locus related to this paper: human-CEL |
| Title : The number of tandem repeats in the carboxyl-ester lipase (CEL) gene as a risk factor in alcoholic and idiopathic chronic pancreatitis - Ragvin_2013_Pancreatology_13_29 |
| Author(s) : Ragvin A , Fjeld K , Weiss FU , Torsvik J , Aghdassi A , Mayerle J , Simon P , Njolstad PR , Lerch MM , Johansson S , Molven A |
| Ref : Pancreatology , 13 :29 , 2013 |
| Abstract : |
| PubMedSearch : Ragvin_2013_Pancreatology_13_29 |
| PubMedID: 23395566 |
| Gene_locus related to this paper: human-CEL |
| Title : Diabetes and pancreatic exocrine dysfunction due to mutations in the carboxyl ester lipase gene-maturity onset diabetes of the young (CEL-MODY): a protein misfolding disease - Johansson_2011_J.Biol.Chem_286_34593 |
| Author(s) : Johansson BB , Torsvik J , Bjorkhaug L , Vesterhus M , Ragvin A , Tjora E , Fjeld K , Hoem D , Johansson S , Raeder H , Lindquist S , Hernell O , Cnop M , Saraste J , Flatmark T , Molven A , Njolstad PR |
| Ref : Journal of Biological Chemistry , 286 :34593 , 2011 |
| Abstract : |
| PubMedSearch : Johansson_2011_J.Biol.Chem_286_34593 |
| PubMedID: 21784842 |
| Gene_locus related to this paper: human-CEL |
| Title : Mutations in the VNTR of the carboxyl-ester lipase gene (CEL) are a rare cause of monogenic diabetes - Torsvik_2010_Hum.Genet_127_55 |
| Author(s) : Torsvik J , Johansson S , Johansen A , Ek J , Minton J , Raeder H , Ellard S , Hattersley A , Pedersen O , Hansen T , Molven A , Njolstad PR |
| Ref : Hum Genet , 127 :55 , 2010 |
| Abstract : |
| PubMedSearch : Torsvik_2010_Hum.Genet_127_55 |
| PubMedID: 19760265 |
| Gene_locus related to this paper: human-CEL |
| Title : Pancreatic function in carboxyl-ester lipase knockout mice - Vesterhus_2010_Pancreatology_10_467 |
| Author(s) : Vesterhus M , Raeder H , Kurpad AJ , Kawamori D , Molven A , Kulkarni RN , Kahn CR , Njolstad PR |
| Ref : Pancreatology , 10 :467 , 2010 |
| Abstract : |
| PubMedSearch : Vesterhus_2010_Pancreatology_10_467 |
| PubMedID: 20720448 |
| Gene_locus related to this paper: human-CEL |
| Title : Lack of pancreatic body and tail in HNF1B mutation carriers - Haldorsen_2008_Diabet.Med_25_782 |
| Author(s) : Haldorsen IS , Vesterhus M , Raeder H , Jensen DK , Sovik O , Molven A , Njolstad PR |
| Ref : Diabet Med , 25 :782 , 2008 |
| Abstract : |
| PubMedSearch : Haldorsen_2008_Diabet.Med_25_782 |
| PubMedID: 18644064 |
| Title : Reduced pancreatic volume in hepatocyte nuclear factor 1A-maturity-onset diabetes of the young - Vesterhus_2008_J.Clin.Endocrinol.Metab_93_3505 |
| Author(s) : Vesterhus M , Haldorsen IS , Raeder H , Molven A , Njolstad PR |
| Ref : J Clinical Endocrinology Metab , 93 :3505 , 2008 |
| Abstract : |
| PubMedSearch : Vesterhus_2008_J.Clin.Endocrinol.Metab_93_3505 |
| PubMedID: 18593771 |
| Title : Pancreatic exocrine dysfunction in maturity-onset diabetes of the young type 3 - Vesterhus_2008_Diabetes.Care_31_306 |
| Author(s) : Vesterhus M , Raeder H , Johansson S , Molven A , Njolstad PR |
| Ref : Diabetes Care , 31 :306 , 2008 |
| Abstract : |
| PubMedSearch : Vesterhus_2008_Diabetes.Care_31_306 |
| PubMedID: 17989309 |
| Gene_locus related to this paper: human-CEL |
| Title : Neurological features and enzyme therapy in patients with endocrine and exocrine pancreas dysfunction due to CEL mutations - Vesterhus_2008_Diabetes.Care_31_1738 |
| Author(s) : Vesterhus M , Raeder H , Aurlien H , Gjesdal CG , Bredrup C , Holm PI , Molven A , Bindoff L , Berstad A , Njolstad PR |
| Ref : Diabetes Care , 31 :1738 , 2008 |
| Abstract : |
| PubMedSearch : Vesterhus_2008_Diabetes.Care_31_1738 |
| PubMedID: 18544793 |
| Gene_locus related to this paper: human-CEL |
| Title : Pancreatic lipomatosis is a structural marker in nondiabetic children with mutations in carboxyl-ester lipase - Raeder_2007_Diabetes_56_444 |
| Author(s) : Raeder H , Haldorsen IS , Ersland L , Gruner R , Taxt T , Sovik O , Molven A , Njolstad PR |
| Ref : Diabetes , 56 :444 , 2007 |
| Abstract : |
| PubMedSearch : Raeder_2007_Diabetes_56_444 |
| PubMedID: 17259390 |
| Title : Mutations in the CEL VNTR cause a syndrome of diabetes and pancreatic exocrine dysfunction. - Raeder_2006_Nat.Genet_38_54 |
| Author(s) : Raeder H , Johansson S , Holm PI , Haldorsen IS , Mas E , Sbarra V , Nermoen I , Eide SA , Grevle L , Bjorkhaug L , Sagen JV , Aksnes L , Svik O , Lombardo D , Molven A , Njolstad PR |
| Ref : Nat Genet , 38 :54 , 2006 |
| Abstract : |
| PubMedSearch : Raeder_2006_Nat.Genet_38_54 |
| PubMedID: 16369531 |
| Gene_locus related to this paper: human-CEL |