| Title : Hybrid molecules with dual inhibition of acetylcholinesterase and Tau hyperphosphorylation: design, inhibitory activity evaluation, apoptosis assessment, and mechanistic exploration - Hu_2025_Chem.Biol.Interact__111848 |
| Author(s) : Hu Q , Xu K , Ran Q , Zhang W , Gan C , Fang Q , Hui A |
| Ref : Chemico-Biological Interactions , :111848 , 2025 |
| Abstract : |
| PubMedSearch : Hu_2025_Chem.Biol.Interact__111848 |
| PubMedID: 41285280 |
| Title : Orlistat Confers Neuroprotection in Traumatic Brain Injury by Modulating Microglial Lipid Metabolism - Yu_2025_Cells_14_1469 |
| Author(s) : Yu C , Ni Y , Xiong Y , Kang H , Jiang Z , Liu Y , Zhang X , Zhao K , Wang S , Gan C , Zhang H |
| Ref : Cells , 14 : , 2025 |
| Abstract : |
| PubMedSearch : Yu_2025_Cells_14_1469 |
| PubMedID: 41002434 |
| Title : Hybrid molecules with dual inhibition of acetylcholinesterase and Tau hyperphosphorylation: design, inhibitory activity evaluation, apoptosis assessment, and mechanistic exploration - Hu_2025_Chem.Biol.Interact__111848 |
| Author(s) : Hu Q , Xu K , Ran Q , Zhang W , Gan C , Fang Q , Hui A |
| Ref : Chemico-Biological Interactions , :111848 , 2025 |
| Abstract : |
| PubMedSearch : Hu_2025_Chem.Biol.Interact__111848 |
| PubMedID: 41285280 |
| Title : Orlistat Confers Neuroprotection in Traumatic Brain Injury by Modulating Microglial Lipid Metabolism - Yu_2025_Cells_14_1469 |
| Author(s) : Yu C , Ni Y , Xiong Y , Kang H , Jiang Z , Liu Y , Zhang X , Zhao K , Wang S , Gan C , Zhang H |
| Ref : Cells , 14 : , 2025 |
| Abstract : |
| PubMedSearch : Yu_2025_Cells_14_1469 |
| PubMedID: 41002434 |
| Title : Orlistat Confers Neuroprotection in Traumatic Brain Injury by Modulating Microglial Lipid Metabolism - Yu_2025_Cells_14_1469 |
| Author(s) : Yu C , Ni Y , Xiong Y , Kang H , Jiang Z , Liu Y , Zhang X , Zhao K , Wang S , Gan C , Zhang H |
| Ref : Cells , 14 : , 2025 |
| Abstract : |
| PubMedSearch : Yu_2025_Cells_14_1469 |
| PubMedID: 41002434 |
| Title : Hybrid molecules with dual inhibition of acetylcholinesterase and Tau hyperphosphorylation: design, inhibitory activity evaluation, apoptosis assessment, and mechanistic exploration - Hu_2025_Chem.Biol.Interact__111848 |
| Author(s) : Hu Q , Xu K , Ran Q , Zhang W , Gan C , Fang Q , Hui A |
| Ref : Chemico-Biological Interactions , :111848 , 2025 |
| Abstract : |
| PubMedSearch : Hu_2025_Chem.Biol.Interact__111848 |
| PubMedID: 41285280 |
| Title : Pharmacokinetics of the KRAS(G12C) inhibitor adagrasib is limited by CYP3A and ABCB1, and influenced by binding to mouse plasma carboxylesterase 1c - Loos_2023_Biomed.Pharmacother_166_115304 |
| Author(s) : Loos NHC , Retmana IA , Rijmers J , Wang Y , Gan C , Lebre MC , Sparidans RW , Beijnen JH , Schinkel AH |
| Ref : Biomed Pharmacother , 166 :115304 , 2023 |
| Abstract : |
| PubMedSearch : Loos_2023_Biomed.Pharmacother_166_115304 |
| PubMedID: 37586117 |
| Title : Carboxylesterase 1 family knockout alters drug disposition and lipid metabolism - Gan_2023_Acta.Pharm.Sin.B_13_618 |
| Author(s) : Gan C , Wang J , Martinez-Chavez A , Hillebrand M , de Vries N , Beukers J , Wagenaar E , Wang Y , Lebre MC , Rosing H , Klarenbeek S , Ali RB , Pritchard C , Huijbers I , Beijnen JH , Schinkel AH |
| Ref : Acta Pharm Sin B , 13 :618 , 2023 |
| Abstract : |
| PubMedSearch : Gan_2023_Acta.Pharm.Sin.B_13_618 |
| PubMedID: 36873183 |
| Gene_locus related to this paper: mouse-Ces1a , mouse-Ces1b , mouse-Ces1c , mouse-Ces1d , mouse-Ces1e , mouse-Ces1f , mouse-Ces1g , mouse-Ces1h |
| Title : Pharmacokinetics of the KRAS(G12C) inhibitor adagrasib is limited by CYP3A and ABCB1, and influenced by binding to mouse plasma carboxylesterase 1c - Loos_2023_Biomed.Pharmacother_166_115304 |
| Author(s) : Loos NHC , Retmana IA , Rijmers J , Wang Y , Gan C , Lebre MC , Sparidans RW , Beijnen JH , Schinkel AH |
| Ref : Biomed Pharmacother , 166 :115304 , 2023 |
| Abstract : |
| PubMedSearch : Loos_2023_Biomed.Pharmacother_166_115304 |
| PubMedID: 37586117 |
| Title : Carboxylesterase 1 family knockout alters drug disposition and lipid metabolism - Gan_2023_Acta.Pharm.Sin.B_13_618 |
| Author(s) : Gan C , Wang J , Martinez-Chavez A , Hillebrand M , de Vries N , Beukers J , Wagenaar E , Wang Y , Lebre MC , Rosing H , Klarenbeek S , Ali RB , Pritchard C , Huijbers I , Beijnen JH , Schinkel AH |
| Ref : Acta Pharm Sin B , 13 :618 , 2023 |
| Abstract : |
| PubMedSearch : Gan_2023_Acta.Pharm.Sin.B_13_618 |
| PubMedID: 36873183 |
| Gene_locus related to this paper: mouse-Ces1a , mouse-Ces1b , mouse-Ces1c , mouse-Ces1d , mouse-Ces1e , mouse-Ces1f , mouse-Ces1g , mouse-Ces1h |
| Title : Pharmacokinetics of the KRAS(G12C) inhibitor adagrasib is limited by CYP3A and ABCB1, and influenced by binding to mouse plasma carboxylesterase 1c - Loos_2023_Biomed.Pharmacother_166_115304 |
| Author(s) : Loos NHC , Retmana IA , Rijmers J , Wang Y , Gan C , Lebre MC , Sparidans RW , Beijnen JH , Schinkel AH |
| Ref : Biomed Pharmacother , 166 :115304 , 2023 |
| Abstract : |
| PubMedSearch : Loos_2023_Biomed.Pharmacother_166_115304 |
| PubMedID: 37586117 |
| Title : Carboxylesterase 1 family knockout alters drug disposition and lipid metabolism - Gan_2023_Acta.Pharm.Sin.B_13_618 |
| Author(s) : Gan C , Wang J , Martinez-Chavez A , Hillebrand M , de Vries N , Beukers J , Wagenaar E , Wang Y , Lebre MC , Rosing H , Klarenbeek S , Ali RB , Pritchard C , Huijbers I , Beijnen JH , Schinkel AH |
| Ref : Acta Pharm Sin B , 13 :618 , 2023 |
| Abstract : |
| PubMedSearch : Gan_2023_Acta.Pharm.Sin.B_13_618 |
| PubMedID: 36873183 |
| Gene_locus related to this paper: mouse-Ces1a , mouse-Ces1b , mouse-Ces1c , mouse-Ces1d , mouse-Ces1e , mouse-Ces1f , mouse-Ces1g , mouse-Ces1h |
| Title : Natural deletion of mouse carboxylesterases Ces1c\/d\/e impacts drug metabolism and metabolic syndrome development - Gan_2023_Biomed.Pharmacother_164_114956 |
| Author(s) : Gan C , Wang J , Wang Y , Martinez-Chavez A , Hillebrand M , de Vries N , Beukers J , Lebre MC , Wagenaar E , Rosing H , Klarenbeek S , Bleijerveld OB , Song JY , Altelaar M , Beijnen JH , Schinkel AH |
| Ref : Biomed Pharmacother , 164 :114956 , 2023 |
| Abstract : |
| PubMedSearch : Gan_2023_Biomed.Pharmacother_164_114956 |
| PubMedID: 37267638 |
| Gene_locus related to this paper: human-CES1 , mouse-Ces1c , mouse-Ces1d , mouse-Ces1e |
| Title : Natural deletion of mouse carboxylesterases Ces1c\/d\/e impacts drug metabolism and metabolic syndrome development - Gan_2023_Biomed.Pharmacother_164_114956 |
| Author(s) : Gan C , Wang J , Wang Y , Martinez-Chavez A , Hillebrand M , de Vries N , Beukers J , Lebre MC , Wagenaar E , Rosing H , Klarenbeek S , Bleijerveld OB , Song JY , Altelaar M , Beijnen JH , Schinkel AH |
| Ref : Biomed Pharmacother , 164 :114956 , 2023 |
| Abstract : |
| PubMedSearch : Gan_2023_Biomed.Pharmacother_164_114956 |
| PubMedID: 37267638 |
| Gene_locus related to this paper: human-CES1 , mouse-Ces1c , mouse-Ces1d , mouse-Ces1e |
| Title : Natural deletion of mouse carboxylesterases Ces1c\/d\/e impacts drug metabolism and metabolic syndrome development - Gan_2023_Biomed.Pharmacother_164_114956 |
| Author(s) : Gan C , Wang J , Wang Y , Martinez-Chavez A , Hillebrand M , de Vries N , Beukers J , Lebre MC , Wagenaar E , Rosing H , Klarenbeek S , Bleijerveld OB , Song JY , Altelaar M , Beijnen JH , Schinkel AH |
| Ref : Biomed Pharmacother , 164 :114956 , 2023 |
| Abstract : |
| PubMedSearch : Gan_2023_Biomed.Pharmacother_164_114956 |
| PubMedID: 37267638 |
| Gene_locus related to this paper: human-CES1 , mouse-Ces1c , mouse-Ces1d , mouse-Ces1e |