Title : Structure-activity relationship studies for the development of inhibitors of murine adipose triglyceride lipase (ATGL) - Mayer_2020_Bioorg.Med.Chem_28_115610 |
Author(s) : Mayer N , Schweiger M , Fuchs E , Migglautsch AK , Doler C , Grabner GF , Romauch M , Melcher MC , Zechner R , Zimmermann R , Breinbauer R |
Ref : Bioorganic & Medicinal Chemistry , 28 :115610 , 2020 |
Abstract : |
PubMedSearch : Mayer_2020_Bioorg.Med.Chem_28_115610 |
PubMedID: 32690265 |
Title : Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice - Schweiger_2017_Nat.Commun_8_14859 |
Author(s) : Schweiger M , Romauch M , Schreiber R , Grabner GF , Hutter S , Kotzbeck P , Benedikt P , Eichmann TO , Yamada S , Knittelfelder O , Diwoky C , Doler C , Mayer N , De Cecco W , Breinbauer R , Zimmermann R , Zechner R |
Ref : Nat Commun , 8 :14859 , 2017 |
Abstract : |
PubMedSearch : Schweiger_2017_Nat.Commun_8_14859 |
PubMedID: 28327588 |
Title : Lysosomal Acid Lipase Hydrolyzes Retinyl Ester and Affects Retinoid Turnover - Grumet_2016_J.Biol.Chem_291_17977 |
Author(s) : Grumet L , Eichmann TO , Taschler U , Zierler KA , Leopold C , Moustafa T , Radovic B , Romauch M , Yan C , Du H , Haemmerle G , Zechner R , Fickert P , Kratky D , Zimmermann R , Lass A |
Ref : Journal of Biological Chemistry , 291 :17977 , 2016 |
Abstract : |
PubMedSearch : Grumet_2016_J.Biol.Chem_291_17977 |
PubMedID: 27354281 |
Gene_locus related to this paper: human-LIPA , mouse-1llip |
Title : Adipose triglyceride lipase is involved in the mobilization of triglyceride and retinoid stores of hepatic stellate cells - Taschler_2015_Biochim.Biophys.Acta_1851_937 |
Author(s) : Taschler U , Schreiber R , Chitraju C , Grabner GF , Romauch M , Wolinski H , Haemmerle G , Breinbauer R , Zechner R , Lass A , Zimmermann R |
Ref : Biochimica & Biophysica Acta , 1851 :937 , 2015 |
Abstract : |
PubMedSearch : Taschler_2015_Biochim.Biophys.Acta_1851_937 |
PubMedID: 25732851 |
Title : alpha\/beta Hydrolase Domain-containing 6 (ABHD6) Degrades the Late Endosomal\/Lysosomal Lipid Bis(monoacylglycero)phosphate - Pribasnig_2015_J.Biol.Chem_290_29869 |
Author(s) : Pribasnig MA , Mrak I , Grabner GF , Taschler U , Knittelfelder O , Scherz B , Eichmann TO , Heier C , Grumet L , Kowaliuk J , Romauch M , Holler S , Anderl F , Wolinski H , Lass A , Breinbauer R , Marsche G , Brown JM , Zimmermann R |
Ref : Journal of Biological Chemistry , 290 :29869 , 2015 |
Abstract : |
PubMedSearch : Pribasnig_2015_J.Biol.Chem_290_29869 |
PubMedID: 26491015 |
Gene_locus related to this paper: human-ABHD6 |
Title : Development of small-molecule inhibitors targeting adipose triglyceride lipase - Mayer_2013_Nat.Chem.Biol_9_785 |
Author(s) : Mayer N , Schweiger M , Romauch M , Grabner GF , Eichmann TO , Fuchs E , Ivkovic J , Heier C , Mrak I , Lass A , Hofler G , Fledelius C , Zechner R , Zimmermann R , Breinbauer R |
Ref : Nat Chemical Biology , 9 :785 , 2013 |
Abstract : |
PubMedSearch : Mayer_2013_Nat.Chem.Biol_9_785 |
PubMedID: 24096302 |