| Title : Mutational scanning pinpoints distinct binding sites of key ATGL regulators in lipolysis - Kohlmayr_2024_Nat.Commun_15_2516 |
| Author(s) : Kohlmayr JM , Grabner GF , Nusser A , Holl A , Manojlovic V , Halwachs B , Masser S , Jany-Luig E , Engelke H , Zimmermann R , Stelzl U |
| Ref : Nat Commun , 15 :2516 , 2024 |
| Abstract : |
| PubMedSearch : Kohlmayr_2024_Nat.Commun_15_2516 |
| PubMedID: 38514628 |
| Title : Inhibition of diacylglycerol lipase beta modulates lipid and endocannabinoid levels in the ex vivo human placenta - Berger_2023_Front.Endocrinol.(Lausanne)_14_1092024 |
| Author(s) : Berger N , van der Wel T , Hirschmugl B , Baernthaler T , Gindlhuber J , Fawzy N , Eichmann T , Birner-Gruenberger R , Zimmermann R , van der Stelt M , Wadsack C |
| Ref : Front Endocrinol (Lausanne) , 14 :1092024 , 2023 |
| Abstract : |
| PubMedSearch : Berger_2023_Front.Endocrinol.(Lausanne)_14_1092024 |
| PubMedID: 36864832 |
| Gene_locus related to this paper: human-DAGLA , human-DAGLB |
| Title : Impact of (intestinal) LAL deficiency on lipid metabolism and macrophage infiltration - Bianco_2023_Mol.Metab__101737 |
| Author(s) : Bianco V , Korbelius M , Vujic N , Akhmetshina A , Amor M , Kolb D , Pirchheim A , Bradic I , Kuentzel KB , Buerger M , Schauer S , Phan HTT , Bulfon D , Hoefler G , Zimmermann R , Kratky D |
| Ref : Mol Metab , :101737 , 2023 |
| Abstract : |
| PubMedSearch : Bianco_2023_Mol.Metab__101737 |
| PubMedID: 37182562 |
| Title : Small-Molecule Inhibitors Targeting Lipolysis in Human Adipocytes - Grabner_2022_J.Am.Chem.Soc__ |
| Author(s) : Grabner GF , Guttenberger N , Mayer N , Migglautsch-Sulzer AK , Lembacher-Fadum C , Fawzy N , Bulfon D , Hofer P , Zullig T , Hartig L , Kulminskaya N , Chalhoub G , Schratter M , Radner FPW , Preiss-Landl K , Masser S , Lass A , Zechner R , Gruber K , Oberer M , Breinbauer R , Zimmermann R |
| Ref : Journal of the American Chemical Society , : , 2022 |
| Abstract : |
| PubMedSearch : Grabner_2022_J.Am.Chem.Soc__ |
| PubMedID: 35362954 |
| Title : Off-target effects of the lysosomal acid lipase inhibitors Lalistat-1 and Lalistat-2 on neutral lipid hydrolases - Bradic_2022_Mol.Metab__101510 |
| Author(s) : Bradic I , Kuentzel KB , Honeder S , Grabner GF , Vujic N , Zimmermann R , Birner-Gruenberger R , Kratky D |
| Ref : Mol Metab , :101510 , 2022 |
| Abstract : |
| PubMedSearch : Bradic_2022_Mol.Metab__101510 |
| PubMedID: 35504532 |
| Title : alpha\/beta-Hydrolase Domain-Containing 6 (ABHD6)- A Multifunctional Lipid Hydrolase - Pusch_2022_Metabolites_12_761 |
| Author(s) : Pusch LM , Riegler-Berket L , Oberer M , Zimmermann R , Taschler U |
| Ref : Metabolites , 12 : , 2022 |
| Abstract : |
| PubMedSearch : Pusch_2022_Metabolites_12_761 |
| PubMedID: 36005632 |
| Gene_locus related to this paper: human-ABHD6 |
| Title : Hepatocyte-specific deletion of adipose triglyceride lipase (ATGL\/PNPLA2) ameliorates dietary induced steatohepatitis in mice - Fuchs_2021_Hepatology__ |
| Author(s) : Fuchs CD , Radun R , Dixon ED , Mlitz V , Timelthaler G , Halilbasic E , Herac M , Jonker JW , Ronda O , Tardelli M , Haemmerle G , Zimmermann R , Scharnagl H , Stojakovic T , Verkade HJ , Trauner M |
| Ref : Hepatology , : , 2021 |
| Abstract : |
| PubMedSearch : Fuchs_2021_Hepatology__ |
| PubMedID: 34387896 |
| Title : Optimized expression and purification of adipose triglyceride lipase improved hydrolysis and transacylation catalytic activities in vitro - Kulminskaya_2021_J.Biol.Chem__101206 |
| Author(s) : Kulminskaya N , Radler C , Viertlmayr R , Heier C , Hofer P , Colaco-Gaspar M , Owens RJ , Zimmermann R , Schreiber R , Zechner R , Oberer M |
| Ref : Journal of Biological Chemistry , :101206 , 2021 |
| Abstract : |
| PubMedSearch : Kulminskaya_2021_J.Biol.Chem__101206 |
| PubMedID: 34543623 |
| Title : Structure-activity relationship studies for the development of inhibitors of murine adipose triglyceride lipase (ATGL) - Mayer_2020_Bioorg.Med.Chem_28_115610 |
| Author(s) : Mayer N , Schweiger M , Fuchs E , Migglautsch AK , Doler C , Grabner GF , Romauch M , Melcher MC , Zechner R , Zimmermann R , Breinbauer R |
| Ref : Bioorganic & Medicinal Chemistry , 28 :115610 , 2020 |
| Abstract : |
| PubMedSearch : Mayer_2020_Bioorg.Med.Chem_28_115610 |
| PubMedID: 32690265 |
| Title : Dysregulated expression of monoacylglycerol lipase is a marker for anti-diabetic drug metformin-targeted therapy to correct impaired neurogenesis and spatial memory in Alzheimer's disease - Syal_2020_Theranostics_10_6337 |
| Author(s) : Syal C , Kosaraju J , Hamilton L , Aumont A , Chu A , Sarma SN , Thomas J , Seegobin M , Dilworth FJ , He L , Wondisford FE , Zimmermann R , Parent M , Fernandes K , Wang J |
| Ref : Theranostics , 10 :6337 , 2020 |
| Abstract : |
| PubMedSearch : Syal_2020_Theranostics_10_6337 |
| PubMedID: 32483456 |
| Title : Lysosomal acid lipase is the major acid retinyl ester hydrolase in cultured human hepatic stellate cells but not essential for retinyl ester degradation - Wagner_2020_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids_1865_158730 |
| Author(s) : Wagner C , Hois V , Pajed L , Pusch LM , Wolinski H , Trauner M , Zimmermann R , Taschler U , Lass A |
| Ref : Biochimica & Biophysica Acta Molecular & Cellular Biology Lipids , 1865 :158730 , 2020 |
| Abstract : |
| PubMedSearch : Wagner_2020_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids_1865_158730 |
| PubMedID: 32361002 |
| Gene_locus related to this paper: human-LIPA |
| Title : Metabolic disease and ABHD6 alter the circulating bis(monoacylglycerol)phosphate profile in mice and humans - Grabner_2019_J.Lipid.Res_60_1020 |
| Author(s) : Grabner GF , Fawzy N , Pribasnig MA , Trieb M , Taschler U , Holzer M , Schweiger M , Wolinski H , Kolb D , Horvath A , Breinbauer R , Rulicke T , Rabl R , Lass A , Stadlbauer V , Hutter-Paier B , Stauber RE , Fickert P , Zechner R , Marsche G , Eichmann TO , Zimmermann R |
| Ref : J Lipid Res , 60 :1020 , 2019 |
| Abstract : |
| PubMedSearch : Grabner_2019_J.Lipid.Res_60_1020 |
| PubMedID: 30894461 |
| Gene_locus related to this paper: human-ABHD6 |
| Title : Hepatocyte-specific deletion of lysosomal acid lipase leads to cholesteryl ester but not triglyceride or retinyl ester accumulation - Pajed_2019_J.Biol.Chem_294_9118 |
| Author(s) : Pajed L , Wagner C , Taschler U , Schreiber R , Kolleritsch S , Fawzy N , Pototschnig I , Schoiswohl G , Pusch LM , Wieser BI , Vesely P , Hoefler G , Eichmann TO , Zimmermann R , Lass A |
| Ref : Journal of Biological Chemistry , 294 :9118 , 2019 |
| Abstract : |
| PubMedSearch : Pajed_2019_J.Biol.Chem_294_9118 |
| PubMedID: 31023823 |
| Title : The alpha\/beta-hydrolase domain-containing 4- and 5-related phospholipase Pummelig controls energy storage in Drosophila - Hehlert_2019_J.Lipid.Res_60_1365 |
| Author(s) : Hehlert P , Hofferek V , Heier C , Eichmann TO , Riedel D , Rosenberg J , Takacs A , Nagy HM , Oberer M , Zimmermann R , Kuhnlein RP |
| Ref : J Lipid Res , 60 :1365 , 2019 |
| Abstract : |
| PubMedSearch : Hehlert_2019_J.Lipid.Res_60_1365 |
| PubMedID: 31164391 |
| Gene_locus related to this paper: drome-CG1882 |
| Title : The crystal structure of monoacylglycerol lipase from M. tuberculosis reveals the basis for specific inhibition - Aschauer_2018_Sci.Rep_8_8948 |
| Author(s) : Aschauer P , Zimmermann R , Breinbauer R , Pavkov-Keller T , Oberer M |
| Ref : Sci Rep , 8 :8948 , 2018 |
| Abstract : |
| PubMedSearch : Aschauer_2018_Sci.Rep_8_8948 |
| PubMedID: 29895832 |
| Gene_locus related to this paper: myctu-rv0183 |
| Title : Hypoxia-inducible lipid droplet-associated protein inhibits adipose triglyceride lipase - Padmanabha_2018_J.Lipid.Res_59_531 |
| Author(s) : Padmanabha Das KM , Wechselberger L , Liziczai M , De la Rosa Rodriguez M , Grabner GF , Heier C , Viertlmayr R , Radler C , Lichtenegger J , Zimmermann R , Borst JW , Zechner R , Kersten S , Oberer M |
| Ref : J Lipid Res , 59 :531 , 2018 |
| Abstract : |
| PubMedSearch : Padmanabha_2018_J.Lipid.Res_59_531 |
| PubMedID: 29326160 |
| Title : Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice - Schweiger_2017_Nat.Commun_8_14859 |
| Author(s) : Schweiger M , Romauch M , Schreiber R , Grabner GF , Hutter S , Kotzbeck P , Benedikt P , Eichmann TO , Yamada S , Knittelfelder O , Diwoky C , Doler C , Mayer N , De Cecco W , Breinbauer R , Zimmermann R , Zechner R |
| Ref : Nat Commun , 8 :14859 , 2017 |
| Abstract : |
| PubMedSearch : Schweiger_2017_Nat.Commun_8_14859 |
| PubMedID: 28327588 |
| Title : Monoglyceride lipase deficiency affects hepatic cholesterol metabolism and lipid-dependent gut transit in ApoE-\/- mice - Vujic_2017_Oncotarget_8_33122 |
| Author(s) : Vujic N , Korbelius M , Leopold C , Duta-Mare M , Rainer S , Schlager S , Goeritzer M , Kolb D , Eichmann TO , Diwoky C , Zimmer A , Zimmermann R , Lass A , Radovic B , Kratky D |
| Ref : Oncotarget , 8 :33122 , 2017 |
| Abstract : |
| PubMedSearch : Vujic_2017_Oncotarget_8_33122 |
| PubMedID: 28380440 |
| Title : Crystal structure of the Saccharomyces cerevisiae monoglyceride lipase Yju3p - Aschauer_2016_Biochim.Biophys.Acta_1861_462 |
| Author(s) : Aschauer P , Rengachari S , Lichtenegger J , Schittmayer M , Das KM , Mayer N , Breinbauer R , Birner-Gruenberger R , Gruber CC , Zimmermann R , Gruber K , Oberer M |
| Ref : Biochimica & Biophysica Acta , 1861 :462 , 2016 |
| Abstract : |
| PubMedSearch : Aschauer_2016_Biochim.Biophys.Acta_1861_462 |
| PubMedID: 26869448 |
| Gene_locus related to this paper: yeast-mgll |
| Title : Monoacylglycerol Lipases Act as Evolutionarily Conserved Regulators of Non-oxidative Ethanol Metabolism - Heier_2016_J.Biol.Chem_291_11865 |
| Author(s) : Heier C , Taschler U , Radulovic M , Aschauer P , Eichmann TO , Grond S , Wolinski H , Oberer M , Zechner R , Kohlwein SD , Zimmermann R |
| Ref : Journal of Biological Chemistry , 291 :11865 , 2016 |
| Abstract : |
| PubMedSearch : Heier_2016_J.Biol.Chem_291_11865 |
| PubMedID: 27036938 |
| Title : Lysosomal Acid Lipase Hydrolyzes Retinyl Ester and Affects Retinoid Turnover - Grumet_2016_J.Biol.Chem_291_17977 |
| Author(s) : Grumet L , Eichmann TO , Taschler U , Zierler KA , Leopold C , Moustafa T , Radovic B , Romauch M , Yan C , Du H , Haemmerle G , Zechner R , Fickert P , Kratky D , Zimmermann R , Lass A |
| Ref : Journal of Biological Chemistry , 291 :17977 , 2016 |
| Abstract : |
| PubMedSearch : Grumet_2016_J.Biol.Chem_291_17977 |
| PubMedID: 27354281 |
| Gene_locus related to this paper: human-LIPA , mouse-1llip |
| Title : Deletion of Monoglyceride Lipase in Astrocytes Attenuates Lipopolysaccharide-induced Neuroinflammation - Grabner_2016_J.Biol.Chem_291_913 |
| Author(s) : Grabner GF , Eichmann TO , Wagner B , Gao Y , Farzi A , Taschler U , Radner FP , Schweiger M , Lass A , Holzer P , Zinser E , Tschop MH , Yi CX , Zimmermann R |
| Ref : Journal of Biological Chemistry , 291 :913 , 2016 |
| Abstract : |
| PubMedSearch : Grabner_2016_J.Biol.Chem_291_913 |
| PubMedID: 26565024 |
| Title : Monoglyceride lipase deficiency modulates endocannabinoid signaling and improves plaque stability in ApoE-knockout mice - Vujic_2015_Atherosclerosis_244_9 |
| Author(s) : Vujic N , Schlager S , Eichmann TO , Madreiter-Sokolowski CT , Goeritzer M , Rainer S , Schauer S , Rosenberger A , Woelfler A , Doddapattar P , Zimmermann R , Hoefler G , Lass A , Graier WF , Radovic B , Kratky D |
| Ref : Atherosclerosis , 244 :9 , 2015 |
| Abstract : |
| PubMedSearch : Vujic_2015_Atherosclerosis_244_9 |
| PubMedID: 26584135 |
| Title : Adipose triglyceride lipase is involved in the mobilization of triglyceride and retinoid stores of hepatic stellate cells - Taschler_2015_Biochim.Biophys.Acta_1851_937 |
| Author(s) : Taschler U , Schreiber R , Chitraju C , Grabner GF , Romauch M , Wolinski H , Haemmerle G , Breinbauer R , Zechner R , Lass A , Zimmermann R |
| Ref : Biochimica & Biophysica Acta , 1851 :937 , 2015 |
| Abstract : |
| PubMedSearch : Taschler_2015_Biochim.Biophys.Acta_1851_937 |
| PubMedID: 25732851 |
| Title : alpha\/beta Hydrolase Domain-containing 6 (ABHD6) Degrades the Late Endosomal\/Lysosomal Lipid Bis(monoacylglycero)phosphate - Pribasnig_2015_J.Biol.Chem_290_29869 |
| Author(s) : Pribasnig MA , Mrak I , Grabner GF , Taschler U , Knittelfelder O , Scherz B , Eichmann TO , Heier C , Grumet L , Kowaliuk J , Romauch M , Holler S , Anderl F , Wolinski H , Lass A , Breinbauer R , Marsche G , Brown JM , Zimmermann R |
| Ref : Journal of Biological Chemistry , 290 :29869 , 2015 |
| Abstract : |
| PubMedSearch : Pribasnig_2015_J.Biol.Chem_290_29869 |
| PubMedID: 26491015 |
| Gene_locus related to this paper: human-ABHD6 |
| Title : Hypophagia and metabolic adaptations in mice with defective ATGL-mediated lipolysis cause resistance to HFD-induced obesity - Schreiber_2015_Proc.Natl.Acad.Sci.U.S.A_112_13850 |
| Author(s) : Schreiber R , Hofer P , Taschler U , Voshol PJ , Rechberger GN , Kotzbeck P , Jaeger D , Preiss-Landl K , Lord CC , Brown JM , Haemmerle G , Zimmermann R , Vidal-Puig A , Zechner R |
| Ref : Proc Natl Acad Sci U S A , 112 :13850 , 2015 |
| Abstract : |
| PubMedSearch : Schreiber_2015_Proc.Natl.Acad.Sci.U.S.A_112_13850 |
| PubMedID: 26508640 |
| Title : Increased tonic cannabinoid CB1R activity and brain region-specific desensitization of CB1R Gi\/o signaling axis in mice with global genetic knockout of monoacylglycerol lipase - Navia-Paldanius_2015_Eur.J.Pharm.Sci_77_180 |
| Author(s) : Navia-Paldanius D , Aaltonen N , Lehtonen M , Savinainen JR , Taschler U , Radner FP , Zimmermann R , Laitinen JT |
| Ref : Eur J Pharm Sci , 77 :180 , 2015 |
| Abstract : |
| PubMedSearch : Navia-Paldanius_2015_Eur.J.Pharm.Sci_77_180 |
| PubMedID: 26070239 |
| Title : Structure-activity studies in the development of a hydrazone based inhibitor of adipose-triglyceride lipase (ATGL) - Mayer_2015_Bioorg.Med.Chem_23_2904 |
| Author(s) : Mayer N , Schweiger M , Melcher MC , Fledelius C , Zechner R , Zimmermann R , Breinbauer R |
| Ref : Bioorganic & Medicinal Chemistry , 23 :2904 , 2015 |
| Abstract : |
| PubMedSearch : Mayer_2015_Bioorg.Med.Chem_23_2904 |
| PubMedID: 25778769 |
| Title : Fatty Acid-binding Proteins Interact with Comparative Gene Identification-58 Linking Lipolysis with Lipid Ligand Shuttling - Hofer_2015_J.Biol.Chem_290_18438 |
| Author(s) : Hofer P , Boeszoermenyi A , Jaeger D , Feiler U , Arthanari H , Mayer N , Zehender F , Rechberger G , Oberer M , Zimmermann R , Lass A , Haemmerle G , Breinbauer R , Zechner R , Preiss-Landl K |
| Ref : Journal of Biological Chemistry , 290 :18438 , 2015 |
| Abstract : |
| PubMedSearch : Hofer_2015_J.Biol.Chem_290_18438 |
| PubMedID: 25953897 |
| Gene_locus related to this paper: human-ABHD5 |
| Title : ATGL and CGI-58 are lipid droplet proteins of the hepatic stellate cell line HSC-T6 - Eichmann_2015_J.Lipid.Res_56_1972 |
| Author(s) : Eichmann TO , Grumet L , Taschler U , Hartler J , Heier C , Woblistin A , Pajed L , Kollroser M , Rechberger G , Thallinger GG , Zechner R , Haemmerle G , Zimmermann R , Lass A |
| Ref : J Lipid Res , 56 :1972 , 2015 |
| Abstract : |
| PubMedSearch : Eichmann_2015_J.Lipid.Res_56_1972 |
| PubMedID: 26330055 |
| Gene_locus related to this paper: human-ABHD5 |
| Title : Adipose triglyceride lipase activity is inhibited by long-chain acyl-coenzyme A - Nagy_2014_Biochim.Biophys.Acta_1841_588 |
| Author(s) : Nagy HM , Paar M , Heier C , Moustafa T , Hofer P , Haemmerle G , Lass A , Zechner R , Oberer M , Zimmermann R |
| Ref : Biochimica & Biophysica Acta , 1841 :588 , 2014 |
| Abstract : |
| PubMedSearch : Nagy_2014_Biochim.Biophys.Acta_1841_588 |
| PubMedID: 24440819 |
| Title : The serine hydrolase ABHD6 Is a critical regulator of the metabolic syndrome - Thomas_2013_Cell.Rep_5_508 |
| Author(s) : Thomas G , Betters JL , Lord CC , Brown AL , Marshall S , Ferguson D , Sawyer J , Davis MA , Melchior JT , Blume LC , Howlett AC , Ivanova PT , Milne SB , Myers DS , Mrak I , Leber V , Heier C , Taschler U , Blankman JL , Cravatt BF , Lee RG , Crooke RM , Graham MJ , Zimmermann R , Brown HA , Brown JM |
| Ref : Cell Rep , 5 :508 , 2013 |
| Abstract : |
| PubMedSearch : Thomas_2013_Cell.Rep_5_508 |
| PubMedID: 24095738 |
| Gene_locus related to this paper: human-ABHD6 |
| Title : Development of small-molecule inhibitors targeting adipose triglyceride lipase - Mayer_2013_Nat.Chem.Biol_9_785 |
| Author(s) : Mayer N , Schweiger M , Romauch M , Grabner GF , Eichmann TO , Fuchs E , Ivkovic J , Heier C , Mrak I , Lass A , Hofler G , Fledelius C , Zechner R , Zimmermann R , Breinbauer R |
| Ref : Nat Chemical Biology , 9 :785 , 2013 |
| Abstract : |
| PubMedSearch : Mayer_2013_Nat.Chem.Biol_9_785 |
| PubMedID: 24096302 |
| Title : Contraction-induced lipolysis is not impaired by inhibition of hormone-sensitive lipase in skeletal muscle - Alsted_2013_J.Physiol_591_5141 |
| Author(s) : Alsted TJ , Ploug T , Prats C , Serup AK , Hoeg L , Schjerling P , Holm C , Zimmermann R , Fledelius C , Galbo H , Kiens B |
| Ref : Journal of Physiology , 591 :5141 , 2013 |
| Abstract : |
| PubMedSearch : Alsted_2013_J.Physiol_591_5141 |
| PubMedID: 23878361 |
| Title : The structure of monoacylglycerol lipase from Bacillus sp. H257 reveals unexpected conservation of the cap architecture between bacterial and human enzymes - Rengachari_2012_Biochim.Biophys.Acta_1821_1012 |
| Author(s) : Rengachari S , Bezerra GA , Riegler-Berket L , Gruber CC , Sturm C , Taschler U , Boeszoermenyi A , Dreveny I , Zimmermann R , Gruber K , Oberer M |
| Ref : Biochimica & Biophysica Acta , 1821 :1012 , 2012 |
| Abstract : |
| PubMedSearch : Rengachari_2012_Biochim.Biophys.Acta_1821_1012 |
| PubMedID: 22561231 |
| Gene_locus related to this paper: bac25-mglp |
| Title : Adiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase - Kumari_2012_Cell.Metab_15_691 |
| Author(s) : Kumari M , Schoiswohl G , Chitraju C , Paar M , Cornaciu I , Rangrez AY , Wongsiriroj N , Nagy HM , Ivanova PT , Scott SA , Knittelfelder O , Rechberger GN , Birner-Gruenberger R , Eder S , Brown HA , Haemmerle G , Oberer M , Lass A , Kershaw EE , Zimmermann R , Zechner R |
| Ref : Cell Metab , 15 :691 , 2012 |
| Abstract : |
| PubMedSearch : Kumari_2012_Cell.Metab_15_691 |
| PubMedID: 22560221 |
| Title : Adipose triglyceride lipase contributes to cancer-associated cachexia - Das_2011_Science_333_233 |
| Author(s) : Das SK , Eder S , Schauer S , Diwoky C , Temmel H , Guertl B , Gorkiewicz G , Tamilarasan KP , Kumari P , Trauner M , Zimmermann R , Vesely P , Haemmerle G , Zechner R , Hoefler G |
| Ref : Science , 333 :233 , 2011 |
| Abstract : |
| PubMedSearch : Das_2011_Science_333_233 |
| PubMedID: 21680814 |
| Gene_locus related to this paper: human-LIPE |
| Title : Lipolysis - a highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores - Lass_2011_Prog.Lipid.Res_50_14 |
| Author(s) : Lass A , Zimmermann R , Oberer M , Zechner R |
| Ref : Prog Lipid Res , 50 :14 , 2011 |
| Abstract : |
| PubMedSearch : Lass_2011_Prog.Lipid.Res_50_14 |
| PubMedID: 21087632 |
| Title : The minimal domain of adipose triglyceride lipase (ATGL) ranges until leucine 254 and can be activated and inhibited by CGI-58 and G0S2, respectively - Cornaciu_2011_PLoS.One_6_e26349 |
| Author(s) : Cornaciu I , Boeszoermenyi A , Lindermuth H , Nagy HM , Cerk IK , Ebner C , Salzburger B , Gruber A , Schweiger M , Zechner R , Lass A , Zimmermann R , Oberer M |
| Ref : PLoS ONE , 6 :e26349 , 2011 |
| Abstract : |
| PubMedSearch : Cornaciu_2011_PLoS.One_6_e26349 |
| PubMedID: 22039468 |
| Gene_locus related to this paper: human-ABHD5 |
| Title : The N-terminal region of comparative gene identification-58 (CGI-58) is important for lipid droplet binding and activation of adipose triglyceride lipase - Gruber_2010_J.Biol.Chem_285_12289 |
| Author(s) : Gruber A , Cornaciu I , Lass A , Schweiger M , Poeschl M , Eder C , Kumari M , Schoiswohl G , Wolinski H , Kohlwein SD , Zechner R , Zimmermann R , Oberer M |
| Ref : Journal of Biological Chemistry , 285 :12289 , 2010 |
| Abstract : |
| PubMedSearch : Gruber_2010_J.Biol.Chem_285_12289 |
| PubMedID: 20164531 |
| Title : Growth retardation, impaired triacylglycerol catabolism, hepatic steatosis, and lethal skin barrier defect in mice lacking comparative gene identification-58 (CGI-58) - Radner_2010_J.Biol.Chem_285_7300 |
| Author(s) : Radner FP , Streith IE , Schoiswohl G , Schweiger M , Kumari M , Eichmann TO , Rechberger G , Koefeler HC , Eder S , Schauer S , Theussl HC , Preiss-Landl K , Lass A , Zimmermann R , Hoefler G , Zechner R , Haemmerle G |
| Ref : Journal of Biological Chemistry , 285 :7300 , 2010 |
| Abstract : |
| PubMedSearch : Radner_2010_J.Biol.Chem_285_7300 |
| PubMedID: 20023287 |
| Gene_locus related to this paper: mouse-abhd5 |
| Title : Identification of Yju3p as functional orthologue of mammalian monoglyceride lipase in the yeast Saccharomycescerevisiae - Heier_2010_Biochim.Biophys.Acta_1801_1063 |
| Author(s) : Heier C , Taschler U , Rengachari S , Oberer M , Wolinski H , Natter K , Kohlwein SD , Leber R , Zimmermann R |
| Ref : Biochimica & Biophysica Acta , 1801 :1063 , 2010 |
| Abstract : |
| PubMedSearch : Heier_2010_Biochim.Biophys.Acta_1801_1063 |
| PubMedID: 20554061 |
| Gene_locus related to this paper: human-MGLL , mouse-MGLL , yeast-mgll |
| Title : Adipose triglyceride lipase plays a key role in the supply of the working muscle with fatty acids - Schoiswohl_2010_J.Lipid.Res_51_490 |
| Author(s) : Schoiswohl G , Schweiger M , Schreiber R , Gorkiewicz G , Preiss-Landl K , Taschler U , Zierler KA , Radner FP , Eichmann TO , Kienesberger PC , Eder S , Lass A , Haemmerle G , Alsted TJ , Kiens B , Hoefler G , Zechner R , Zimmermann R |
| Ref : J Lipid Res , 51 :490 , 2010 |
| Abstract : |
| PubMedSearch : Schoiswohl_2010_J.Lipid.Res_51_490 |
| PubMedID: 19965578 |
| Title : Cholesteryl ester hydrolase activity is abolished in HSL-\/- macrophages but unchanged in macrophages lacking KIAA1363 - Buchebner_2010_J.Lipid.Res_51_2896 |
| Author(s) : Buchebner M , Pfeifer T , Rathke N , Chandak PG , Lass A , Schreiber R , Kratzer A , Zimmermann R , Sattler W , Koefeler H , Frohlich E , Kostner GM , Birner-Gruenberger R , Chiang KP , Haemmerle G , Zechner R , Levak-Frank S , Cravatt B , Kratky D |
| Ref : J Lipid Res , 51 :2896 , 2010 |
| Abstract : |
| PubMedSearch : Buchebner_2010_J.Lipid.Res_51_2896 |
| PubMedID: 20625037 |
| Gene_locus related to this paper: human-NCEH1 , mouse-Q8BLF1 |
| Title : Fate of fat: the role of adipose triglyceride lipase in lipolysis - Zimmermann_2009_Biochim.Biophys.Acta_1791_494 |
| Author(s) : Zimmermann R , Lass A , Haemmerle G , Zechner R |
| Ref : Biochimica & Biophysica Acta , 1791 :494 , 2009 |
| Abstract : |
| PubMedSearch : Zimmermann_2009_Biochim.Biophys.Acta_1791_494 |
| PubMedID: 19010445 |
| Title : Adipose triglyceride lipase and the lipolytic catabolism of cellular fat stores - Zechner_2009_J.Lipid.Res_50_3 |
| Author(s) : Zechner R , Kienesberger PC , Haemmerle G , Zimmermann R , Lass A |
| Ref : J Lipid Res , 50 :3 , 2009 |
| Abstract : |
| PubMedSearch : Zechner_2009_J.Lipid.Res_50_3 |
| PubMedID: 18952573 |
| Title : Adipose triglyceride lipase in human skeletal muscle is upregulated by exercise training - Alsted_2009_Am.J.Physiol.Endocrinol.Metab_296_E445 |
| Author(s) : Alsted TJ , Nybo L , Schweiger M , Fledelius C , Jacobsen P , Zimmermann R , Zechner R , Kiens B |
| Ref : American Journal of Physiology Endocrinol Metab , 296 :E445 , 2009 |
| Abstract : |
| PubMedSearch : Alsted_2009_Am.J.Physiol.Endocrinol.Metab_296_E445 |
| PubMedID: 19106247 |
| Title : Neutral lipid storage disease: genetic disorders caused by mutations in adipose triglyceride lipase\/PNPLA2 or CGI-58\/ABHD5 - Schweiger_2009_Am.J.Physiol.Endocrinol.Metab_297_E289 |
| Author(s) : Schweiger M , Lass A , Zimmermann R , Eichmann TO , Zechner R |
| Ref : American Journal of Physiology Endocrinol Metab , 297 :E289 , 2009 |
| Abstract : |
| PubMedSearch : Schweiger_2009_Am.J.Physiol.Endocrinol.Metab_297_E289 |
| PubMedID: 19401457 |
| Gene_locus related to this paper: human-ABHD5 |
| Title : The C-terminal region of human adipose triglyceride lipase affects enzyme activity and lipid droplet binding - Schweiger_2008_J.Biol.Chem_283_17211 |
| Author(s) : Schweiger M , Schoiswohl G , Lass A , Radner FP , Haemmerle G , Malli R , Graier W , Cornaciu I , Oberer M , Salvayre R , Fischer J , Zechner R , Zimmermann R |
| Ref : Journal of Biological Chemistry , 283 :17211 , 2008 |
| Abstract : |
| PubMedSearch : Schweiger_2008_J.Biol.Chem_283_17211 |
| PubMedID: 18445597 |
| Title : Identification of an insulin-regulated lysophospholipase with homology to neuropathy target esterase - Kienesberger_2008_J.Biol.Chem_283_5908 |
| Author(s) : Kienesberger PC , Lass A , Preiss-Landl K , Wolinski H , Kohlwein SD , Zimmermann R , Zechner R |
| Ref : Journal of Biological Chemistry , 283 :5908 , 2008 |
| Abstract : |
| PubMedSearch : Kienesberger_2008_J.Biol.Chem_283_5908 |
| PubMedID: 18086666 |
| Title : LPL-mediated lipolysis of VLDL induces an upregulation of AU-rich mRNAs and an activation of HuR in endothelial cells - Tschernatsch_2006_Atherosclerosis_189_310 |
| Author(s) : Tschernatsch MM , Mlecnik B , Trajanoski Z , Zechner R , Zimmermann R |
| Ref : Atherosclerosis , 189 :310 , 2006 |
| Abstract : |
| PubMedSearch : Tschernatsch_2006_Atherosclerosis_189_310 |
| PubMedID: 16494882 |
| Title : Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome - Lass_2006_Cell.Metab_3_309 |
| Author(s) : Lass A , Zimmermann R , Haemmerle G , Riederer M , Schoiswohl G , Schweiger M , Kienesberger P , Strauss JG , Gorkiewicz G , Zechner R |
| Ref : Cell Metab , 3 :309 , 2006 |
| Abstract : |
| PubMedSearch : Lass_2006_Cell.Metab_3_309 |
| PubMedID: 16679289 |
| Gene_locus related to this paper: human-ABHD5 |
| Title : Adipose triglyceride lipase and hormone-sensitive lipase are the major enzymes in adipose tissue triacylglycerol catabolism - Schweiger_2006_J.Biol.Chem_281_40236 |
| Author(s) : Schweiger M , Schreiber R , Haemmerle G , Lass A , Fledelius C , Jacobsen P , Tornqvist H , Zechner R , Zimmermann R |
| Ref : Journal of Biological Chemistry , 281 :40236 , 2006 |
| Abstract : |
| PubMedSearch : Schweiger_2006_J.Biol.Chem_281_40236 |
| PubMedID: 17074755 |
| Title : The ATGL gene is associated with free fatty acids, triglycerides, and type 2 diabetes - Schoenborn_2006_Diabetes_55_1270 |
| Author(s) : Schoenborn V , Heid IM , Vollmert C , Lingenhel A , Adams TD , Hopkins PN , Illig T , Zimmermann R , Zechner R , Hunt SC , Kronenberg F |
| Ref : Diabetes , 55 :1270 , 2006 |
| Abstract : |
| PubMedSearch : Schoenborn_2006_Diabetes_55_1270 |
| PubMedID: 16644682 |
| Title : Obese yeast: triglyceride lipolysis is functionally conserved from mammals to yeast - Kurat_2006_J.Biol.Chem_281_491 |
| Author(s) : Kurat CF , Natter K , Petschnigg J , Wolinski H , Scheuringer K , Scholz H , Zimmermann R , Leber R , Zechner R , Kohlwein SD |
| Ref : Journal of Biological Chemistry , 281 :491 , 2006 |
| Abstract : |
| PubMedSearch : Kurat_2006_J.Biol.Chem_281_491 |
| PubMedID: 16267052 |
| Title : Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase - Haemmerle_2006_Science_312_734 |
| Author(s) : Haemmerle G , Lass A , Zimmermann R , Gorkiewicz G , Meyer C , Rozman J , Heldmaier G , Maier R , Theussl C , Eder S , Kratky D , Wagner EF , Klingenspor M , Hoefler G , Zechner R |
| Ref : Science , 312 :734 , 2006 |
| Abstract : |
| PubMedSearch : Haemmerle_2006_Science_312_734 |
| PubMedID: 16675698 |
| Title : The lipolytic proteome of mouse adipose tissue - Birner-Gruenberger_2005_Mol.Cell.Proteomics_4_1710 |
| Author(s) : Birner-Gruenberger R , Susani-Etzerodt H , Waldhuber M , Riesenhuber G , Schmidinger H , Rechberger G , Kollroser M , Strauss JG , Lass A , Zimmermann R , Haemmerle G , Zechner R , Hermetter A |
| Ref : Mol Cell Proteomics , 4 :1710 , 2005 |
| Abstract : |
| PubMedSearch : Birner-Gruenberger_2005_Mol.Cell.Proteomics_4_1710 |
| PubMedID: 16048907 |
| Title : The lipid droplet enzyme Tgl1p hydrolyzes both steryl esters and triglycerides in the yeast, Saccharomyces cerevisiae - Jandrositz_2005_Biochim.Biophys.Acta_1735_50 |
| Author(s) : Jandrositz A , Petschnigg J , Zimmermann R , Natter K , Scholze H , Hermetter A , Kohlwein SD , Leber R |
| Ref : Biochimica & Biophysica Acta , 1735 :50 , 2005 |
| Abstract : |
| PubMedSearch : Jandrositz_2005_Biochim.Biophys.Acta_1735_50 |
| PubMedID: 15922657 |
| Gene_locus related to this paper: yeast-tgl1 |
| Title : Lipolysis: pathway under construction - Zechner_2005_Curr.Opin.Lipidol_16_333 |
| Author(s) : Zechner R , Strauss JG , Haemmerle G , Lass A , Zimmermann R |
| Ref : Curr Opin Lipidol , 16 :333 , 2005 |
| Abstract : |
| PubMedSearch : Zechner_2005_Curr.Opin.Lipidol_16_333 |
| PubMedID: 15891395 |
| Title : Endothelial lipase provides an alternative pathway for FFA uptake in lipoprotein lipase-deficient mouse adipose tissue - Kratky_2005_J.Clin.Invest_115_161 |
| Author(s) : Kratky D , Zimmermann R , Wagner EM , Strauss JG , Jin W , Kostner GM , Haemmerle G , Rader DJ , Zechner R |
| Ref : J Clinical Investigation , 115 :161 , 2005 |
| Abstract : |
| PubMedSearch : Kratky_2005_J.Clin.Invest_115_161 |
| PubMedID: 15630456 |
| Title : Increased hepatic insulin sensitivity together with decreased hepatic triglyceride stores in hormone-sensitive lipase-deficient mice - Voshol_2003_Endocrinology_144_3456 |
| Author(s) : Voshol PJ , Haemmerle G , Ouwens DM , Zimmermann R , Zechner R , Teusink B , Maassen JA , Havekes LM , Romijn JA |
| Ref : Endocrinology , 144 :3456 , 2003 |
| Abstract : |
| PubMedSearch : Voshol_2003_Endocrinology_144_3456 |
| PubMedID: 12865325 |
| Gene_locus related to this paper: mouse-hslip |
| Title : Letting lipids go: hormone-sensitive lipase - Haemmerle_2003_Curr.Opin.Lipidol_14_289 |
| Author(s) : Haemmerle G , Zimmermann R , Zechner R |
| Ref : Curr Opin Lipidol , 14 :289 , 2003 |
| Abstract : |
| PubMedSearch : Haemmerle_2003_Curr.Opin.Lipidol_14_289 |
| PubMedID: 12840660 |
| Title : Hormone-sensitive lipase deficiency in mice changes the plasma lipid profile by affecting the tissue-specific expression pattern of lipoprotein lipase in adipose tissue and muscle - Haemmerle_2002_J.Biol.Chem_277_12946 |
| Author(s) : Haemmerle G , Zimmermann R , Strauss JG , Kratky D , Riederer M , Knipping G , Zechner R |
| Ref : Journal of Biological Chemistry , 277 :12946 , 2002 |
| Abstract : |
| PubMedSearch : Haemmerle_2002_J.Biol.Chem_277_12946 |
| PubMedID: 11809748 |
| Title : Lipoprotein lipase: the regulation of tissue specific expression and its role in lipid and energy metabolism - Preiss-Landl_2002_Curr.Opin.Lipidol_13_471 |
| Author(s) : Preiss-Landl K , Zimmermann R , Hammerle G , Zechner R |
| Ref : Curr Opin Lipidol , 13 :471 , 2002 |
| Abstract : |
| PubMedSearch : Preiss-Landl_2002_Curr.Opin.Lipidol_13_471 |
| PubMedID: 12352010 |
| Title : Endogenously produced lipoprotein lipase enhances the binding and cell association of native, mildly oxidized and moderately oxidized low-density lipoprotein in mouse peritoneal macrophages - Wang_1999_Biochem.J_343 Pt 2_347 |
| Author(s) : Wang X , Greilberger J , Levak-Frank S , Zimmermann R , Zechner R , Jurgens G |
| Ref : Biochemical Journal , 343 Pt 2 :347 , 1999 |
| Abstract : |
| PubMedSearch : Wang_1999_Biochem.J_343 Pt 2_347 |
| PubMedID: 10510299 |