Zechner R

General

Full name : Zechner Rudolf

First name : Rudolf

Mail : Institute of Molecular Biosciences, University of Graz, Graz, A-8010

Zip Code :

City :

Country : Austria

Email :

Phone :

Fax :

Website :

Directory :

References (92)

Title : PNPLA-mediated lipid hydrolysis and transacylation - At the intersection of catabolism and anabolism - Colaco-Gaspar_2023_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids__159410
Author(s) : Colaco-Gaspar M , Hofer P , Oberer M , Zechner R
Ref : Biochimica & Biophysica Acta Molecular & Cellular Biology Lipids , :159410 , 2023
PubMedID: 37951382

Title : Unmasking Crucial Residues in Adipose Triglyceride Lipase (ATGL) for Co-Activation with Comparative Gene Identification-58 (CGI-58) - Kulminskaya_2023_J.Lipid.Res__100491
Author(s) : Kulminskaya N , Rodriguez Gamez CF , Hofer P , Cerk IK , Dubey N , Viertlmayr R , Sagmeister T , Pavkov-Keller T , Zechner R , Oberer M
Ref : J Lipid Res , :100491 , 2023
PubMedID: 38135254
Gene_locus related to this paper: human-ABHD5 , mouse-abhd5

Title : The Potential Roles of Transacylation in Intracellular Lipolysis and Related Qssa Approximations - Elias_2023_Bull.Math.Biol_85_82
Author(s) : Elias J , Fellner K , Hofer P , Oberer M , Schreiber R , Zechner R
Ref : Bull Math Biol , 85 :82 , 2023
PubMedID: 37544001

Title : Small-Molecule Inhibitors Targeting Lipolysis in Human Adipocytes - Grabner_2022_J.Am.Chem.Soc__
Author(s) : Grabner GF , Guttenberger N , Mayer N , Migglautsch-Sulzer AK , Lembacher-Fadum C , Fawzy N , Bulfon D , Hofer P , Zullig T , Hartig L , Kulminskaya N , Chalhoub G , Schratter M , Radner FPW , Preiss-Landl K , Masser S , Lass A , Zechner R , Gruber K , Oberer M , Breinbauer R , Zimmermann R
Ref : Journal of the American Chemical Society , : , 2022
PubMedID: 35362954

Title : Adipose triglyceride lipase mediated lipid catabolism is essential for bronchiolar regeneration - Kanti_2022_JCI.Insight__
Author(s) : Kanti MM , Striessnig-Bina I , Wieser BI , Schauer S , Leitinger G , Eichmann TO , Schweiger M , Winkler M , Winter E , Lana A , Kufferath I , Marsh LM , Kwapiszewska G , Zechner R , Hoefler G , Vesely PW
Ref : JCI Insight , : , 2022
PubMedID: 35349484

Title : Rosiglitazone reverses inflammation in epididymal white adipose tissue in hormone-sensitive lipase-knockout mice - Kotzbeck_2022_J.Lipid.Res__100305
Author(s) : Kotzbeck P , Taschler U , Haudum C , Foessl I , Schoiswohl G , Boulgaropoulos B , Bounab K , Einsiedler J , Pajed L , Tilp A , Schwarz A , Eichmann TO , Obermayer-Pietsch B , Giordano A , Cinti S , Zechner R , Pieber TR
Ref : J Lipid Res , :100305 , 2022
PubMedID: 36273647

Title : Optimized expression and purification of adipose triglyceride lipase improved hydrolysis and transacylation catalytic activities in vitro - Kulminskaya_2021_J.Biol.Chem__101206
Author(s) : Kulminskaya N , Radler C , Viertlmayr R , Heier C , Hofer P , Colaco-Gaspar M , Owens RJ , Zimmermann R , Schreiber R , Zechner R , Oberer M
Ref : Journal of Biological Chemistry , :101206 , 2021
PubMedID: 34543623

Title : Distinct roles of adipose triglyceride lipase and hormone-sensitive lipase in the catabolism of triacylglycerol estolides - Brejchova_2021_Proc.Natl.Acad.Sci.U.S.A_118_
Author(s) : Brejchova K , Radner FPW , Balas L , Paluchova V , Cajka T , Chodounska H , Kudova E , Schratter M , Schreiber R , Durand T , Zechner R , Kuda O
Ref : Proc Natl Acad Sci U S A , 118 : , 2021
PubMedID: 33372146

Title : Structure-activity relationship studies for the development of inhibitors of murine adipose triglyceride lipase (ATGL) - Mayer_2020_Bioorg.Med.Chem_28_115610
Author(s) : Mayer N , Schweiger M , Fuchs E , Migglautsch AK , Doler C , Grabner GF , Romauch M , Melcher MC , Zechner R , Zimmermann R , Breinbauer R
Ref : Bioorganic & Medicinal Chemistry , 28 :115610 , 2020
PubMedID: 32690265

Title : Enhanced monoacylglycerol lipolysis by ABHD6 promotes NSCLC pathogenesis - Tang_2020_EBioMedicine_53_102696
Author(s) : Tang Z , Xie H , Heier C , Huang J , Zheng Q , Eichmann TO , Schoiswohl G , Ni J , Zechner R , Ni S , Hao H
Ref : EBioMedicine , 53 :102696 , 2020
PubMedID: 32143183

Title : Metabolic disease and ABHD6 alter the circulating bis(monoacylglycerol)phosphate profile in mice and humans - Grabner_2019_J.Lipid.Res_60_1020
Author(s) : Grabner GF , Fawzy N , Pribasnig MA , Trieb M , Taschler U , Holzer M , Schweiger M , Wolinski H , Kolb D , Horvath A , Breinbauer R , Rulicke T , Rabl R , Lass A , Stadlbauer V , Hutter-Paier B , Stauber RE , Fickert P , Zechner R , Marsche G , Eichmann TO , Zimmermann R
Ref : J Lipid Res , 60 :1020 , 2019
PubMedID: 30894461
Gene_locus related to this paper: human-ABHD6

Title : Hypoxia-inducible lipid droplet-associated protein inhibits adipose triglyceride lipase - Padmanabha_2018_J.Lipid.Res_59_531
Author(s) : Padmanabha Das KM , Wechselberger L , Liziczai M , De la Rosa Rodriguez M , Grabner GF , Heier C , Viertlmayr R , Radler C , Lichtenegger J , Zimmermann R , Borst JW , Zechner R , Kersten S , Oberer M
Ref : J Lipid Res , 59 :531 , 2018
PubMedID: 29326160

Title : Lipolysis Triggers a Systemic Insulin Response Essential for Efficient Energy Replenishment of Activated Brown Adipose Tissue in Mice - Heine_2018_Cell.Metab_28_644
Author(s) : Heine M , Fischer AW , Schlein C , Jung C , Straub LG , Gottschling K , Mangels N , Yuan Y , Nilsson SK , Liebscher G , Chen O , Schreiber R , Zechner R , Scheja L , Heeren J
Ref : Cell Metab , 28 :644 , 2018
PubMedID: 30033199

Title : Skin Barrier Development Depends on CGI-58 Protein Expression during Late-Stage Keratinocyte Differentiation - Grond_2017_J.Invest.Dermatol_137_403
Author(s) : Grond S , Radner FP , Eichmann TO , Kolb D , Grabner GF , Wolinski H , Gruber R , Hofer P , Heier C , Schauer S , Rulicke T , Hoefler G , Schmuth M , Elias PM , Lass A , Zechner R , Haemmerle G
Ref : Journal of Investigative Dermatology , 137 :403 , 2017
PubMedID: 27725204
Gene_locus related to this paper: human-ABHD5

Title : Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice - Schweiger_2017_Nat.Commun_8_14859
Author(s) : Schweiger M , Romauch M , Schreiber R , Grabner GF , Hutter S , Kotzbeck P , Benedikt P , Eichmann TO , Yamada S , Knittelfelder O , Diwoky C , Doler C , Mayer N , De Cecco W , Breinbauer R , Zimmermann R , Zechner R
Ref : Nat Commun , 8 :14859 , 2017
PubMedID: 28327588

Title : Mice lacking lipid droplet-associated hydrolase, a gene linked to human prostate cancer, have normal cholesterol ester metabolism - Kory_2017_J.Lipid.Res_58_226
Author(s) : Kory N , Grond S , Kamat SS , Li Z , Krahmer N , Chitraju C , Zhou P , Frohlich F , Semova I , Ejsing C , Zechner R , Cravatt BF , Farese RV, Jr. , Walther TC
Ref : J Lipid Res , 58 :226 , 2017
PubMedID: 27836991
Gene_locus related to this paper: human-LDAH , mouse-Ldah

Title : Monoacylglycerol Lipases Act as Evolutionarily Conserved Regulators of Non-oxidative Ethanol Metabolism - Heier_2016_J.Biol.Chem_291_11865
Author(s) : Heier C , Taschler U , Radulovic M , Aschauer P , Eichmann TO , Grond S , Wolinski H , Oberer M , Zechner R , Kohlwein SD , Zimmermann R
Ref : Journal of Biological Chemistry , 291 :11865 , 2016
PubMedID: 27036938

Title : Lysosomal Acid Lipase Hydrolyzes Retinyl Ester and Affects Retinoid Turnover - Grumet_2016_J.Biol.Chem_291_17977
Author(s) : Grumet L , Eichmann TO , Taschler U , Zierler KA , Leopold C , Moustafa T , Radovic B , Romauch M , Yan C , Du H , Haemmerle G , Zechner R , Fickert P , Kratky D , Zimmermann R , Lass A
Ref : Journal of Biological Chemistry , 291 :17977 , 2016
PubMedID: 27354281
Gene_locus related to this paper: human-LIPA , mouse-1llip

Title : Regulation of Hepatic Triacylglycerol Metabolism by CGI-58 Does Not Require ATGL Co-activation - Lord_2016_Cell.Rep_16_939
Author(s) : Lord CC , Ferguson D , Thomas G , Brown AL , Schugar RC , Burrows A , Gromovsky AD , Betters J , Neumann C , Sacks J , Marshall S , Watts R , Schweiger M , Lee RG , Crooke RM , Graham MJ , Lathia JD , Sakaguchi TF , Lehner R , Haemmerle G , Zechner R , Brown JM
Ref : Cell Rep , 16 :939 , 2016
PubMedID: 27396333

Title : Micro RNA-124a regulates lipolysis via adipose triglyceride lipase and comparative gene identification 58 - Das_2015_Int.J.Mol.Sci_16_8555
Author(s) : Das SK , Stadelmeyer E , Schauer S , Schwarz A , Strohmaier H , Claudel T , Zechner R , Hoefler G , Vesely PW
Ref : Int J Mol Sci , 16 :8555 , 2015
PubMedID: 25894224

Title : Structure-activity studies in the development of a hydrazone based inhibitor of adipose-triglyceride lipase (ATGL) - Mayer_2015_Bioorg.Med.Chem_23_2904
Author(s) : Mayer N , Schweiger M , Melcher MC , Fledelius C , Zechner R , Zimmermann R , Breinbauer R
Ref : Bioorganic & Medicinal Chemistry , 23 :2904 , 2015
PubMedID: 25778769

Title : Structure of a CGI-58 Motif Provides the Molecular Basis of Lipid Droplet Anchoring - Boeszoermenyi_2015_J.Biol.Chem_290_26361
Author(s) : Boeszoermenyi A , Nagy HM , Arthanari H , Pillip CJ , Lindermuth H , Luna RE , Wagner G , Zechner R , Zangger K , Oberer M
Ref : Journal of Biological Chemistry , 290 :26361 , 2015
PubMedID: 26350461
Gene_locus related to this paper: human-ABHD5

Title : Aging. Lysosomal signaling molecules regulate longevity in Caenorhabditis elegans - Folick_2015_Science_347_83
Author(s) : Folick A , Oakley HD , Yu Y , Armstrong EH , Kumari M , Sanor L , Moore DD , Ortlund EA , Zechner R , Wang MC
Ref : Science , 347 :83 , 2015
PubMedID: 25554789
Gene_locus related to this paper: caeel-K04A8.5

Title : Hypophagia and metabolic adaptations in mice with defective ATGL-mediated lipolysis cause resistance to HFD-induced obesity - Schreiber_2015_Proc.Natl.Acad.Sci.U.S.A_112_13850
Author(s) : Schreiber R , Hofer P , Taschler U , Voshol PJ , Rechberger GN , Kotzbeck P , Jaeger D , Preiss-Landl K , Lord CC , Brown JM , Haemmerle G , Zimmermann R , Vidal-Puig A , Zechner R
Ref : Proc Natl Acad Sci U S A , 112 :13850 , 2015
PubMedID: 26508640

Title : Adipose triglyceride lipase is involved in the mobilization of triglyceride and retinoid stores of hepatic stellate cells - Taschler_2015_Biochim.Biophys.Acta_1851_937
Author(s) : Taschler U , Schreiber R , Chitraju C , Grabner GF , Romauch M , Wolinski H , Haemmerle G , Breinbauer R , Zechner R , Lass A , Zimmermann R
Ref : Biochimica & Biophysica Acta , 1851 :937 , 2015
PubMedID: 25732851

Title : Fatty Acid-binding Proteins Interact with Comparative Gene Identification-58 Linking Lipolysis with Lipid Ligand Shuttling - Hofer_2015_J.Biol.Chem_290_18438
Author(s) : Hofer P , Boeszoermenyi A , Jaeger D , Feiler U , Arthanari H , Mayer N , Zehender F , Rechberger G , Oberer M , Zimmermann R , Lass A , Haemmerle G , Breinbauer R , Zechner R , Preiss-Landl K
Ref : Journal of Biological Chemistry , 290 :18438 , 2015
PubMedID: 25953897
Gene_locus related to this paper: human-ABHD5

Title : ATGL and CGI-58 are lipid droplet proteins of the hepatic stellate cell line HSC-T6 - Eichmann_2015_J.Lipid.Res_56_1972
Author(s) : Eichmann TO , Grumet L , Taschler U , Hartler J , Heier C , Woblistin A , Pajed L , Kollroser M , Rechberger G , Thallinger GG , Zechner R , Haemmerle G , Zimmermann R , Lass A
Ref : J Lipid Res , 56 :1972 , 2015
PubMedID: 26330055
Gene_locus related to this paper: human-ABHD5

Title : The hepatitis C virus core protein inhibits adipose triglyceride lipase (ATGL)-mediated lipid mobilization and enhances the ATGL interaction with comparative gene identification 58 (CGI-58) and lipid droplets - Camus_2014_J.Biol.Chem_289_35770
Author(s) : Camus G , Schweiger M , Herker E , Harris C , Kondratowicz AS , Tsou CL , Farese RV, Jr. , Herath K , Previs SF , Roddy TP , Pinto S , Zechner R , Ott M
Ref : Journal of Biological Chemistry , 289 :35770 , 2014
PubMedID: 25381252

Title : Hormone-sensitive lipase deficiency in humans - Zechner_2014_Cell.Metab_20_199
Author(s) : Zechner R , Langin D
Ref : Cell Metab , 20 :199 , 2014
PubMedID: 25100058
Gene_locus related to this paper: human-LIPE

Title : Comparative gene identification-58\/alpha\/beta hydrolase domain 5: more than just an adipose triglyceride lipase activator? - Zierler_2014_Curr.Opin.Lipidol_25_102
Author(s) : Zierler KA , Zechner R , Haemmerle G
Ref : Curr Opin Lipidol , 25 :102 , 2014
PubMedID: 24565921

Title : Fat-specific protein 27 (FSP27) interacts with adipose triglyceride lipase (ATGL) to regulate lipolysis and insulin sensitivity in human adipocytes - Grahn_2014_J.Biol.Chem_289_12029
Author(s) : Grahn THM , Kaur R , Yin J , Schweiger M , Sharma VM , Lee MJ , Ido Y , Smas CM , Zechner R , Lass A , Puri V
Ref : Journal of Biological Chemistry , 289 :12029 , 2014
PubMedID: 24627478

Title : Adipose triglyceride lipase activity is inhibited by long-chain acyl-coenzyme A - Nagy_2014_Biochim.Biophys.Acta_1841_588
Author(s) : Nagy HM , Paar M , Heier C , Moustafa T , Hofer P , Haemmerle G , Lass A , Zechner R , Oberer M , Zimmermann R
Ref : Biochimica & Biophysica Acta , 1841 :588 , 2014
PubMedID: 24440819

Title : Early structural and metabolic cardiac remodelling in response to inducible adipose triglyceride lipase ablation - Kienesberger_2013_Cardiovasc.Res_99_442
Author(s) : Kienesberger PC , Pulinilkunnil T , Nagendran J , Young ME , Bogner-Strauss JG , Hackl H , Khadour R , Heydari E , Haemmerle G , Zechner R , Kershaw EE , Dyck JR
Ref : Cardiovascular Research , 99 :442 , 2013
PubMedID: 23708736

Title : Development of small-molecule inhibitors targeting adipose triglyceride lipase - Mayer_2013_Nat.Chem.Biol_9_785
Author(s) : Mayer N , Schweiger M , Romauch M , Grabner GF , Eichmann TO , Fuchs E , Ivkovic J , Heier C , Mrak I , Lass A , Hofler G , Fledelius C , Zechner R , Zimmermann R , Breinbauer R
Ref : Nat Chemical Biology , 9 :785 , 2013
PubMedID: 24096302

Title : Biochemistry and pathophysiology of intravascular and intracellular lipolysis - Young_2013_Genes.Dev_27_459
Author(s) : Young SG , Zechner R
Ref : Genes Dev , 27 :459 , 2013
PubMedID: 23475957
Gene_locus related to this paper: human-ABHD5 , human-LPL

Title : Adiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase - Kumari_2012_Cell.Metab_15_691
Author(s) : Kumari M , Schoiswohl G , Chitraju C , Paar M , Cornaciu I , Rangrez AY , Wongsiriroj N , Nagy HM , Ivanova PT , Scott SA , Knittelfelder O , Rechberger GN , Birner-Gruenberger R , Eder S , Brown HA , Haemmerle G , Oberer M , Lass A , Kershaw EE , Zimmermann R , Zechner R
Ref : Cell Metab , 15 :691 , 2012
PubMedID: 22560221

Title : Adipose Triglyceride Lipase (ATGL) and Hormone-Sensitive Lipase (HSL) Deficiencies Affect Expression of Lipolytic Activities in Mouse Adipose Tissues - Morak_2012_Mol.Cell.Proteomics_11_1777
Author(s) : Morak M , Schmidinger H , Riesenhuber G , Rechberger GN , Kollroser M , Haemmerle G , Zechner R , Kronenberg F , Hermetter A
Ref : Mol Cell Proteomics , 11 :1777 , 2012
PubMedID: 22984285

Title : Cardiac dysfunction in adipose triglyceride lipase deficiency: treatment with a PPARalpha agonist - Wolkart_2012_Br.J.Pharmacol_165_380
Author(s) : Wolkart G , Schrammel A , Dorffel K , Haemmerle G , Zechner R , Mayer B
Ref : British Journal of Pharmacology , 165 :380 , 2012
PubMedID: 21585347

Title : Resveratrol regulates lipolysis via adipose triglyceride lipase - Lasa_2012_J.Nutr.Biochem_23_379
Author(s) : Lasa A , Schweiger M , Kotzbeck P , Churruca I , Simon E , Zechner R , Portillo MP
Ref : J Nutr Biochem , 23 :379 , 2012
PubMedID: 21543206

Title : Adipose triglyceride lipase contributes to cancer-associated cachexia - Das_2011_Science_333_233
Author(s) : Das SK , Eder S , Schauer S , Diwoky C , Temmel H , Guertl B , Gorkiewicz G , Tamilarasan KP , Kumari P , Trauner M , Zimmermann R , Vesely P , Haemmerle G , Zechner R , Hoefler G
Ref : Science , 333 :233 , 2011
PubMedID: 21680814
Gene_locus related to this paper: human-LIPE

Title : Macrophage adipose triglyceride lipase deficiency attenuates atherosclerotic lesion development in low-density lipoprotein receptor knockout mice - Lammers_2011_Arterioscler.Thromb.Vasc.Biol_31_67
Author(s) : Lammers B , Chandak PG , Aflaki E , Van Puijvelde GH , Radovic B , Hildebrand RB , Meurs I , Out R , Kuiper J , van Berkel TJ , Kolb D , Haemmerle G , Zechner R , Levak-Frank S , Van Eck M , Kratky D
Ref : Arterioscler Thromb Vasc Biol , 31 :67 , 2011
PubMedID: 21030715

Title : Lipolysis - a highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores - Lass_2011_Prog.Lipid.Res_50_14
Author(s) : Lass A , Zimmermann R , Oberer M , Zechner R
Ref : Prog Lipid Res , 50 :14 , 2011
PubMedID: 21087632

Title : Recent insights into the structure and function of comparative gene identification-58 - Oberer_2011_Curr.Opin.Lipidol_22_149
Author(s) : Oberer M , Boeszoermenyi A , Nagy HM , Zechner R
Ref : Curr Opin Lipidol , 22 :149 , 2011
PubMedID: 21494142
Gene_locus related to this paper: human-ABHD5

Title : The minimal domain of adipose triglyceride lipase (ATGL) ranges until leucine 254 and can be activated and inhibited by CGI-58 and G0S2, respectively - Cornaciu_2011_PLoS.One_6_e26349
Author(s) : Cornaciu I , Boeszoermenyi A , Lindermuth H , Nagy HM , Cerk IK , Ebner C , Salzburger B , Gruber A , Schweiger M , Zechner R , Lass A , Zimmermann R , Oberer M
Ref : PLoS ONE , 6 :e26349 , 2011
PubMedID: 22039468
Gene_locus related to this paper: human-ABHD5

Title : Efficient phagocytosis requires triacylglycerol hydrolysis by adipose triglyceride lipase - Chandak_2010_J.Biol.Chem_285_20192
Author(s) : Chandak PG , Radovic B , Aflaki E , Kolb D , Buchebner M , Frohlich E , Magnes C , Sinner F , Haemmerle G , Zechner R , Tabas I , Levak-Frank S , Kratky D
Ref : Journal of Biological Chemistry , 285 :20192 , 2010
PubMedID: 20424161

Title : Growth retardation, impaired triacylglycerol catabolism, hepatic steatosis, and lethal skin barrier defect in mice lacking comparative gene identification-58 (CGI-58) - Radner_2010_J.Biol.Chem_285_7300
Author(s) : Radner FP , Streith IE , Schoiswohl G , Schweiger M , Kumari M , Eichmann TO , Rechberger G , Koefeler HC , Eder S , Schauer S , Theussl HC , Preiss-Landl K , Lass A , Zimmermann R , Hoefler G , Zechner R , Haemmerle G
Ref : Journal of Biological Chemistry , 285 :7300 , 2010
PubMedID: 20023287
Gene_locus related to this paper: mouse-abhd5

Title : Cholesteryl ester hydrolase activity is abolished in HSL-\/- macrophages but unchanged in macrophages lacking KIAA1363 - Buchebner_2010_J.Lipid.Res_51_2896
Author(s) : Buchebner M , Pfeifer T , Rathke N , Chandak PG , Lass A , Schreiber R , Kratzer A , Zimmermann R , Sattler W , Koefeler H , Frohlich E , Kostner GM , Birner-Gruenberger R , Chiang KP , Haemmerle G , Zechner R , Levak-Frank S , Cravatt B , Kratky D
Ref : J Lipid Res , 51 :2896 , 2010
PubMedID: 20625037
Gene_locus related to this paper: human-NCEH1 , mouse-Q8BLF1

Title : Recommended nomenclature for five mammalian carboxylesterase gene families: human, mouse, and rat genes and proteins - Holmes_2010_Mamm.Genome_21_427
Author(s) : Holmes RS , Wright MW , Laulederkind SJ , Cox LA , Hosokawa M , Imai T , Ishibashi S , Lehner R , Miyazaki M , Perkins EJ , Potter PM , Redinbo MR , Robert J , Satoh T , Yamashita T , Yan B , Yokoi T , Zechner R , Maltais LJ
Ref : Mamm Genome , 21 :427 , 2010
PubMedID: 20931200
Gene_locus related to this paper: human-CES1 , human-CES2 , human-CES3 , human-CES4A , human-CES5A

Title : The N-terminal region of comparative gene identification-58 (CGI-58) is important for lipid droplet binding and activation of adipose triglyceride lipase - Gruber_2010_J.Biol.Chem_285_12289
Author(s) : Gruber A , Cornaciu I , Lass A , Schweiger M , Poeschl M , Eder C , Kumari M , Schoiswohl G , Wolinski H , Kohlwein SD , Zechner R , Zimmermann R , Oberer M
Ref : Journal of Biological Chemistry , 285 :12289 , 2010
PubMedID: 20164531

Title : Weight loss and lipolysis promote a dynamic immune response in murine adipose tissue - Kosteli_2010_J.Clin.Invest_120_3466
Author(s) : Kosteli A , Sugaru E , Haemmerle G , Martin JF , Lei J , Zechner R , Ferrante AW, Jr.
Ref : J Clinical Investigation , 120 :3466 , 2010
PubMedID: 20877011

Title : Adipose triglyceride lipase plays a key role in the supply of the working muscle with fatty acids - Schoiswohl_2010_J.Lipid.Res_51_490
Author(s) : Schoiswohl G , Schweiger M , Schreiber R , Gorkiewicz G , Preiss-Landl K , Taschler U , Zierler KA , Radner FP , Eichmann TO , Kienesberger PC , Eder S , Lass A , Haemmerle G , Alsted TJ , Kiens B , Hoefler G , Zechner R , Zimmermann R
Ref : J Lipid Res , 51 :490 , 2010
PubMedID: 19965578

Title : A beta cell-specific knockout of hormone-sensitive lipase in mice results in hyperglycaemia and disruption of exocytosis - Fex_2009_Diabetologia_52_271
Author(s) : Fex M , Haemmerle G , Wierup N , Dekker-Nitert M , Rehn M , Ristow M , Zechner R , Sundler F , Holm C , Eliasson L , Mulder H
Ref : Diabetologia , 52 :271 , 2009
PubMedID: 19023560

Title : Fate of fat: the role of adipose triglyceride lipase in lipolysis - Zimmermann_2009_Biochim.Biophys.Acta_1791_494
Author(s) : Zimmermann R , Lass A , Haemmerle G , Zechner R
Ref : Biochimica & Biophysica Acta , 1791 :494 , 2009
PubMedID: 19010445

Title : Adipose triglyceride lipase and the lipolytic catabolism of cellular fat stores - Zechner_2009_J.Lipid.Res_50_3
Author(s) : Zechner R , Kienesberger PC , Haemmerle G , Zimmermann R , Lass A
Ref : J Lipid Res , 50 :3 , 2009
PubMedID: 18952573

Title : Adipose triglyceride lipase deficiency causes tissue-specific changes in insulin signaling - Kienesberger_2009_J.Biol.Chem_284_30218
Author(s) : Kienesberger PC , Lee D , Pulinilkunnil T , Brenner DS , Cai L , Magnes C , Koefeler HC , Streith IE , Rechberger GN , Haemmerle G , Flier JS , Zechner R , Kim YB , Kershaw EE
Ref : Journal of Biological Chemistry , 284 :30218 , 2009
PubMedID: 19723629

Title : Neutral lipid storage disease: genetic disorders caused by mutations in adipose triglyceride lipase\/PNPLA2 or CGI-58\/ABHD5 - Schweiger_2009_Am.J.Physiol.Endocrinol.Metab_297_E289
Author(s) : Schweiger M , Lass A , Zimmermann R , Eichmann TO , Zechner R
Ref : American Journal of Physiology Endocrinol Metab , 297 :E289 , 2009
PubMedID: 19401457
Gene_locus related to this paper: human-ABHD5

Title : Adipose triglyceride lipase in human skeletal muscle is upregulated by exercise training - Alsted_2009_Am.J.Physiol.Endocrinol.Metab_296_E445
Author(s) : Alsted TJ , Nybo L , Schweiger M , Fledelius C , Jacobsen P , Zimmermann R , Zechner R , Kiens B
Ref : American Journal of Physiology Endocrinol Metab , 296 :E445 , 2009
PubMedID: 19106247

Title : Adipose triglyceride lipase is implicated in fuel- and non-fuel-stimulated insulin secretion - Peyot_2009_J.Biol.Chem_284_16848
Author(s) : Peyot ML , Guay C , Latour MG , Lamontagne J , Lussier R , Pineda M , Ruderman NB , Haemmerle G , Zechner R , Joly E , Madiraju SR , Poitout V , Prentki M
Ref : Journal of Biological Chemistry , 284 :16848 , 2009
PubMedID: 19389712

Title : The C-terminal region of human adipose triglyceride lipase affects enzyme activity and lipid droplet binding - Schweiger_2008_J.Biol.Chem_283_17211
Author(s) : Schweiger M , Schoiswohl G , Lass A , Radner FP , Haemmerle G , Malli R , Graier W , Cornaciu I , Oberer M , Salvayre R , Fischer J , Zechner R , Zimmermann R
Ref : Journal of Biological Chemistry , 283 :17211 , 2008
PubMedID: 18445597

Title : Differential transcriptional modulation of biological processes in adipocyte triglyceride lipase and hormone-sensitive lipase-deficient mice - Pinent_2008_Genomics_92_26
Author(s) : Pinent M , Hackl H , Burkard TR , Prokesch A , Papak C , Scheideler M , Hammerle G , Zechner R , Trajanoski Z , Strauss JG
Ref : Genomics , 92 :26 , 2008
PubMedID: 18572100

Title : Hepatic overexpression of hormone-sensitive lipase and adipose triglyceride lipase promotes fatty acid oxidation, stimulates direct release of free fatty acids, and ameliorates steatosis - Reid_2008_J.Biol.Chem_283_13087
Author(s) : Reid BN , Ables GP , Otlivanchik OA , Schoiswohl G , Zechner R , Blaner WS , Goldberg IJ , Schwabe RF , Chua SC, Jr. , Huang LS
Ref : Journal of Biological Chemistry , 283 :13087 , 2008
PubMedID: 18337240

Title : Identification of an insulin-regulated lysophospholipase with homology to neuropathy target esterase - Kienesberger_2008_J.Biol.Chem_283_5908
Author(s) : Kienesberger PC , Lass A , Preiss-Landl K , Wolinski H , Kohlwein SD , Zimmermann R , Zechner R
Ref : Journal of Biological Chemistry , 283 :5908 , 2008
PubMedID: 18086666

Title : Mitochondria maintain maturation and secretion of lipoprotein lipase in the endoplasmic reticulum - Osibow_2006_Biochem.J_396_173
Author(s) : Osibow K , Frank S , Malli R , Zechner R , Graier WF
Ref : Biochemical Journal , 396 :173 , 2006
PubMedID: 16466345

Title : LPL-mediated lipolysis of VLDL induces an upregulation of AU-rich mRNAs and an activation of HuR in endothelial cells - Tschernatsch_2006_Atherosclerosis_189_310
Author(s) : Tschernatsch MM , Mlecnik B , Trajanoski Z , Zechner R , Zimmermann R
Ref : Atherosclerosis , 189 :310 , 2006
PubMedID: 16494882

Title : Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome - Lass_2006_Cell.Metab_3_309
Author(s) : Lass A , Zimmermann R , Haemmerle G , Riederer M , Schoiswohl G , Schweiger M , Kienesberger P , Strauss JG , Gorkiewicz G , Zechner R
Ref : Cell Metab , 3 :309 , 2006
PubMedID: 16679289
Gene_locus related to this paper: human-ABHD5

Title : The ATGL gene is associated with free fatty acids, triglycerides, and type 2 diabetes - Schoenborn_2006_Diabetes_55_1270
Author(s) : Schoenborn V , Heid IM , Vollmert C , Lingenhel A , Adams TD , Hopkins PN , Illig T , Zimmermann R , Zechner R , Hunt SC , Kronenberg F
Ref : Diabetes , 55 :1270 , 2006
PubMedID: 16644682

Title : Obese yeast: triglyceride lipolysis is functionally conserved from mammals to yeast - Kurat_2006_J.Biol.Chem_281_491
Author(s) : Kurat CF , Natter K , Petschnigg J , Wolinski H , Scheuringer K , Scholz H , Zimmermann R , Leber R , Zechner R , Kohlwein SD
Ref : Journal of Biological Chemistry , 281 :491 , 2006
PubMedID: 16267052

Title : Adipose triglyceride lipase and hormone-sensitive lipase are the major enzymes in adipose tissue triacylglycerol catabolism - Schweiger_2006_J.Biol.Chem_281_40236
Author(s) : Schweiger M , Schreiber R , Haemmerle G , Lass A , Fledelius C , Jacobsen P , Tornqvist H , Zechner R , Zimmermann R
Ref : Journal of Biological Chemistry , 281 :40236 , 2006
PubMedID: 17074755

Title : Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase - Haemmerle_2006_Science_312_734
Author(s) : Haemmerle G , Lass A , Zimmermann R , Gorkiewicz G , Meyer C , Rozman J , Heldmaier G , Maier R , Theussl C , Eder S , Kratky D , Wagner EF , Klingenspor M , Hoefler G , Zechner R
Ref : Science , 312 :734 , 2006
PubMedID: 16675698

Title : The lipolytic proteome of mouse adipose tissue - Birner-Gruenberger_2005_Mol.Cell.Proteomics_4_1710
Author(s) : Birner-Gruenberger R , Susani-Etzerodt H , Waldhuber M , Riesenhuber G , Schmidinger H , Rechberger G , Kollroser M , Strauss JG , Lass A , Zimmermann R , Haemmerle G , Zechner R , Hermetter A
Ref : Mol Cell Proteomics , 4 :1710 , 2005
PubMedID: 16048907

Title : Endothelial lipase provides an alternative pathway for FFA uptake in lipoprotein lipase-deficient mouse adipose tissue - Kratky_2005_J.Clin.Invest_115_161
Author(s) : Kratky D , Zimmermann R , Wagner EM , Strauss JG , Jin W , Kostner GM , Haemmerle G , Rader DJ , Zechner R
Ref : J Clinical Investigation , 115 :161 , 2005
PubMedID: 15630456

Title : Lipolysis: pathway under construction - Zechner_2005_Curr.Opin.Lipidol_16_333
Author(s) : Zechner R , Strauss JG , Haemmerle G , Lass A , Zimmermann R
Ref : Curr Opin Lipidol , 16 :333 , 2005
PubMedID: 15891395

Title : Dependence of lipoprotein-lipase-catalyzed triacylglycerol hydrolysis on droplet size of synthetic monodisperse emulsions measured with static light scattering - Fritz_2004_J.Colloid.Interface.Sci_275_642
Author(s) : Fritz G , Wagner EM , Lindner H , Hofmann W , Zechner R , Glatter O
Ref : J Colloid Interface Sci , 275 :642 , 2004
PubMedID: 15178298

Title : Cardiac-specific knock-out of lipoprotein lipase alters plasma lipoprotein triglyceride metabolism and cardiac gene expression - Augustus_2004_J.Biol.Chem_279_25050
Author(s) : Augustus A , Yagyu H , Haemmerle G , Bensadoun A , Vikramadithyan RK , Park SY , Kim JK , Zechner R , Goldberg IJ
Ref : Journal of Biological Chemistry , 279 :25050 , 2004
PubMedID: 15028738

Title : Letting lipids go: hormone-sensitive lipase - Haemmerle_2003_Curr.Opin.Lipidol_14_289
Author(s) : Haemmerle G , Zimmermann R , Zechner R
Ref : Curr Opin Lipidol , 14 :289 , 2003
PubMedID: 12840660

Title : Increased hepatic insulin sensitivity together with decreased hepatic triglyceride stores in hormone-sensitive lipase-deficient mice - Voshol_2003_Endocrinology_144_3456
Author(s) : Voshol PJ , Haemmerle G , Ouwens DM , Zimmermann R , Zechner R , Teusink B , Maassen JA , Havekes LM , Romijn JA
Ref : Endocrinology , 144 :3456 , 2003
PubMedID: 12865325
Gene_locus related to this paper: mouse-hslip

Title : Inactive lipoprotein lipase (LPL) alone increases selective cholesterol ester uptake in vivo, whereas in the presence of active LPL it also increases triglyceride hydrolysis and whole particle lipoprotein uptake - Merkel_2002_J.Biol.Chem_277_7405
Author(s) : Merkel M , Heeren J , Dudeck W , Rinninger F , Radner H , Breslow JL , Goldberg IJ , Zechner R , Greten H
Ref : Journal of Biological Chemistry , 277 :7405 , 2002
PubMedID: 11751882

Title : Hormone-sensitive lipase deficiency in mice changes the plasma lipid profile by affecting the tissue-specific expression pattern of lipoprotein lipase in adipose tissue and muscle - Haemmerle_2002_J.Biol.Chem_277_12946
Author(s) : Haemmerle G , Zimmermann R , Strauss JG , Kratky D , Riederer M , Knipping G , Zechner R
Ref : Journal of Biological Chemistry , 277 :12946 , 2002
PubMedID: 11809748

Title : Lipoprotein lipase: the regulation of tissue specific expression and its role in lipid and energy metabolism - Preiss-Landl_2002_Curr.Opin.Lipidol_13_471
Author(s) : Preiss-Landl K , Zimmermann R , Hammerle G , Zechner R
Ref : Curr Opin Lipidol , 13 :471 , 2002
PubMedID: 12352010

Title : Tissue-specific activity of lipoprotein lipase in skeletal muscle regulates the expression of uncoupling protein 3 in transgenic mouse models - Kratky_2001_Biochem.J_355_647
Author(s) : Kratky D , Strauss JG , Zechner R
Ref : Biochemical Journal , 355 :647 , 2001
PubMedID: 11311126

Title : In muscle-specific lipoprotein lipase-overexpressing mice, muscle triglyceride content is increased without inhibition of insulin-stimulated whole-body and muscle-specific glucose uptake - Voshol_2001_Diabetes_50_2585
Author(s) : Voshol PJ , Jong MC , Dahlmans VE , Kratky D , Levak-Frank S , Zechner R , Romijn JA , Havekes LM
Ref : Diabetes , 50 :2585 , 2001
PubMedID: 11679438

Title : Induced mutant mouse lines that express lipoprotein lipase in cardiac muscle, but not in skeletal muscle and adipose tissue, have normal plasma triglyceride and high-density lipoprotein-cholesterol levels - Levak-Frank_1999_Proc.Natl.Acad.Sci.U.S.A_96_3165
Author(s) : Levak-Frank S , Hofmann W , Weinstock PH , Radner H , Sattler W , Breslow JL , Zechner R
Ref : Proc Natl Acad Sci U S A , 96 :3165 , 1999
PubMedID: 10077655

Title : Endogenously produced lipoprotein lipase enhances the binding and cell association of native, mildly oxidized and moderately oxidized low-density lipoprotein in mouse peritoneal macrophages - Wang_1999_Biochem.J_343 Pt 2_347
Author(s) : Wang X , Greilberger J , Levak-Frank S , Zimmermann R , Zechner R , Jurgens G
Ref : Biochemical Journal , 343 Pt 2 :347 , 1999
PubMedID: 10510299

Title : Induced mutant mice expressing lipoprotein lipase exclusively in muscle have subnormal triglycerides yet reduced high density lipoprotein cholesterol levels in plasma - Levak-Frank_1997_J.Biol.Chem_272_17182
Author(s) : Levak-Frank S , Weinstock PH , Hayek T , Verdery R , Hofmann W , Ramakrishnan R , Sattler W , Breslow JL , Zechner R
Ref : Journal of Biological Chemistry , 272 :17182 , 1997
PubMedID: 9202040

Title : The tissue-specific expression of lipoprotein lipase: implications for energy and lipoprotein metabolism - Zechner_1997_Curr.Opin.Lipidol_8_77
Author(s) : Zechner R
Ref : Curr Opin Lipidol , 8 :77 , 1997
PubMedID: 9183545

Title : Severe hypertriglyceridemia, reduced high density lipoprotein, and neonatal death in lipoprotein lipase knockout mice. Mild hypertriglyceridemia with impaired very low density lipoprotein clearance in heterozygotes - Weinstock_1995_J.Clin.Invest_96_2555
Author(s) : Weinstock PH , Bisgaier CL , Aalto-Setala K , Radner H , Ramakrishnan R , Levak-Frank S , Essenburg AD , Zechner R , Breslow JL
Ref : J Clinical Investigation , 96 :2555 , 1995
PubMedID: 8675619

Title : Muscle-specific overexpression of lipoprotein lipase causes a severe myopathy characterized by proliferation of mitochondria and peroxisomes in transgenic mice - Levak-Frank_1995_J.Clin.Invest_96_976
Author(s) : Levak-Frank S , Radner H , Walsh A , Stollberger R , Knipping G , Hoefler G , Sattler W , Weinstock PH , Breslow JL , Zechner R
Ref : J Clinical Investigation , 96 :976 , 1995
PubMedID: 7635990

Title : A single G to A nucleotide transition in exon IV of the lecithin: cholesterol acyltransferase (LCAT) gene results in an Arg140 to His substitution and causes LCAT-deficiency - Steyrer_1995_Hum.Genet_96_105
Author(s) : Steyrer E , Haubenwallner S , Horl G , Giessauf W , Kostner GM , Zechner R
Ref : Hum Genet , 96 :105 , 1995
PubMedID: 7607641

Title : A novel missense mutation in the gene for lipoprotein lipase resulting in a highly conservative amino acid substitution (Asp180-->Glu) causes familial chylomicronemia (type I hyperlipoproteinemia) - Haubenwallner_1993_Genomics_18_392
Author(s) : Haubenwallner S , Horl G , Shachter NS , Presta E , Fried SK , Hofler G , Kostner GM , Breslow JL , Zechner R
Ref : Genomics , 18 :392 , 1993
PubMedID: 8288243
Gene_locus related to this paper: human-LPL

Title : The structure of the mouse lipoprotein lipase gene: a B1 repetitive element is inserted into the 3' untranslated region of the mRNA - Zechner_1991_Genomics_11_62
Author(s) : Zechner R , Newman TC , Steiner E , Breslow JL
Ref : Genomics , 11 :62 , 1991
PubMedID: 1765386

Title : Rapid and simple isolation procedure for lipoprotein lipase from human milk - Zechner_1990_Biochim.Biophys.Acta_1044_20
Author(s) : Zechner R
Ref : Biochimica & Biophysica Acta , 1044 :20 , 1990
PubMedID: 2340307
Gene_locus related to this paper: human-LPL

Title : Plasma lipids and lipoproteins of a patient with cholesteryl ester storage disease - Kostner_1985_J.Inherit.Metab.Dis_8_9
Author(s) : Kostner GM , Hadorn B , Roscher A , Zechner R
Ref : J Inherit Metab Dis , 8 :9 , 1985
PubMedID: 3921762