Brown JM

References (18)

Title : Re-examining the potential of targeting ABHD6 in multiple sclerosis: Efficacy of systemic and peripherally restricted inhibitors in experimental autoimmune encephalomyelitis - Manterola_2018_Neuropharmacol_141_181
Author(s) : Manterola A , Bernal-Chico A , Cipriani R , Ruiz A , Perez-Samartin A , Moreno-Rodriguez M , Hsu KL , Cravatt BF , Brown JM , Rodriguez-Puertas R , Matute C , Mato S
Ref : Neuropharmacology , 141 :181 , 2018
PubMedID: 30171986
Gene_locus related to this paper: human-ABHD6

Title : Deregulation of the endocannabinoid system and therapeutic potential of ABHD6 blockade in the cuprizone model of demyelination - Manterola_2018_Biochem.Pharmacol_157_189
Author(s) : Manterola A , Bernal-Chico A , Cipriani R , Canedo-Antelo M , Moreno-Garcia A , Martin-Fontecha M , Perez-Cerda F , Sanchez-Gomez MV , Ortega-Gutierrez S , Brown JM , Hsu KL , Cravatt B , Matute C , Mato S
Ref : Biochemical Pharmacology , 157 :189 , 2018
PubMedID: 30075103
Gene_locus related to this paper: human-ABHD6

Title : An in vivo multiplexed small-molecule screening platform - Gruner_2016_Nat.Methods_13_883
Author(s) : Gruner BM , Schulze CJ , Yang D , Ogasawara D , Dix MM , Rogers ZN , Chuang CH , McFarland CD , Chiou SH , Brown JM , Cravatt BF , Bogyo M , Winslow MM
Ref : Nat Methods , 13 :883 , 2016
PubMedID: 27617390

Title : alpha\/beta-Hydrolase Domain 6 Deletion Induces Adipose Browning and Prevents Obesity and Type 2 Diabetes - Zhao_2016_Cell.Rep_14_2872
Author(s) : Zhao S , Mugabo Y , Ballentine G , Attane C , Iglesias J , Poursharifi P , Zhang D , Nguyen TA , Erb H , Prentki R , Peyot ML , Joly E , Tobin S , Fulton S , Brown JM , Madiraju SR , Prentki M
Ref : Cell Rep , 14 :2872 , 2016
PubMedID: 26997277
Gene_locus related to this paper: human-ABHD6 , mouse-ABHD6

Title : Regulation of Hepatic Triacylglycerol Metabolism by CGI-58 Does Not Require ATGL Co-activation - Lord_2016_Cell.Rep_16_939
Author(s) : Lord CC , Ferguson D , Thomas G , Brown AL , Schugar RC , Burrows A , Gromovsky AD , Betters J , Neumann C , Sacks J , Marshall S , Watts R , Schweiger M , Lee RG , Crooke RM , Graham MJ , Lathia JD , Sakaguchi TF , Lehner R , Haemmerle G , Zechner R , Brown JM
Ref : Cell Rep , 16 :939 , 2016
PubMedID: 27396333

Title : alpha\/beta Hydrolase Domain-containing 6 (ABHD6) Degrades the Late Endosomal\/Lysosomal Lipid Bis(monoacylglycero)phosphate - Pribasnig_2015_J.Biol.Chem_290_29869
Author(s) : Pribasnig MA , Mrak I , Grabner GF , Taschler U , Knittelfelder O , Scherz B , Eichmann TO , Heier C , Grumet L , Kowaliuk J , Romauch M , Holler S , Anderl F , Wolinski H , Lass A , Breinbauer R , Marsche G , Brown JM , Zimmermann R
Ref : Journal of Biological Chemistry , 290 :29869 , 2015
PubMedID: 26491015
Gene_locus related to this paper: human-ABHD6

Title : Hypophagia and metabolic adaptations in mice with defective ATGL-mediated lipolysis cause resistance to HFD-induced obesity - Schreiber_2015_Proc.Natl.Acad.Sci.U.S.A_112_13850
Author(s) : Schreiber R , Hofer P , Taschler U , Voshol PJ , Rechberger GN , Kotzbeck P , Jaeger D , Preiss-Landl K , Lord CC , Brown JM , Haemmerle G , Zimmermann R , Vidal-Puig A , Zechner R
Ref : Proc Natl Acad Sci U S A , 112 :13850 , 2015
PubMedID: 26508640

Title : alpha\/beta-Hydrolase domain-6-accessible monoacylglycerol controls glucose-stimulated insulin secretion - Zhao_2014_Cell.Metab_19_993
Author(s) : Zhao S , Mugabo Y , Iglesias J , Xie L , Delghingaro-Augusto V , Lussier R , Peyot ML , Joly E , Taib B , Davis MA , Brown JM , Abousalham A , Gaisano H , Madiraju SR , Prentki M
Ref : Cell Metab , 19 :993 , 2014
PubMedID: 24814481

Title : Deletion of CGI-58 or adipose triglyceride lipase differently affects macrophage function and atherosclerosis - Goeritzer_2014_J.Lipid.Res_55_2562
Author(s) : Goeritzer M , Schlager S , Radovic B , Madreiter CT , Rainer S , Thomas G , Lord CC , Sacks J , Brown AL , Vujic N , Obrowsky S , Sachdev V , Kolb D , Chandak PG , Graier WF , Sattler W , Brown JM , Kratky D
Ref : J Lipid Res , 55 :2562 , 2014
PubMedID: 25316883
Gene_locus related to this paper: mouse-abhd5

Title : In vivo metabolite profiling as a means to identify uncharacterized lipase function: Recent success stories within the alpha beta hydrolase domain (ABHD) enzyme family - Thomas_2014_Biochim.Biophys.Acta_1841_1097
Author(s) : Thomas G , Brown AL , Brown JM
Ref : Biochimica & Biophysica Acta , 1841 :1097 , 2014
PubMedID: 24423940
Gene_locus related to this paper: human-ABHD3 , human-ABHD6 , human-ABHD12

Title : Nocardia vulneris sp. nov., isolated from wounds of human patients in North America - Lasker_2014_Antonie.Van.Leeuwenhoek_106_543
Author(s) : Lasker BA , Bell M , Klenk HP , Sproer C , Schumann C , Schumann P , Brown JM
Ref : Antonie Van Leeuwenhoek , 106 :543 , 2014
PubMedID: 25015412
Gene_locus related to this paper: 9noca-k0el65 , 9noca-k0eub3 , 9noca-a0a034u924 , 9noca-a0a0c1b4e1 , 9noca-a0a0c1czw1 , 9noca-a0a0c1d845 , 9noca-a0a0c1cxc1

Title : The serine hydrolase ABHD6 Is a critical regulator of the metabolic syndrome - Thomas_2013_Cell.Rep_5_508
Author(s) : Thomas G , Betters JL , Lord CC , Brown AL , Marshall S , Ferguson D , Sawyer J , Davis MA , Melchior JT , Blume LC , Howlett AC , Ivanova PT , Milne SB , Myers DS , Mrak I , Leber V , Heier C , Taschler U , Blankman JL , Cravatt BF , Lee RG , Crooke RM , Graham MJ , Zimmermann R , Brown HA , Brown JM
Ref : Cell Rep , 5 :508 , 2013
PubMedID: 24095738
Gene_locus related to this paper: human-ABHD6

Title : Mammalian alpha beta hydrolase domain (ABHD) proteins: Lipid metabolizing enzymes at the interface of cell signaling and energy metabolism - Lord_2013_Biochim.Biophys.Acta_1831_792
Author(s) : Lord CC , Thomas G , Brown JM
Ref : Biochimica & Biophysica Acta , 1831 :792 , 2013
PubMedID: 23328280

Title : CGI-58\/ABHD5-derived signaling lipids regulate systemic inflammation and insulin action - Lord_2012_Diabetes_61_355
Author(s) : Lord CC , Betters JL , Ivanova PT , Milne SB , Myers DS , Madenspacher J , Thomas G , Chung S , Liu M , Davis MA , Lee RG , Crooke RM , Graham MJ , Parks JS , Brasaemle DL , Fessler MB , Brown HA , Brown JM
Ref : Diabetes , 61 :355 , 2012
PubMedID: 22228714
Gene_locus related to this paper: human-ABHD5

Title : Distinct roles for alpha-beta hydrolase domain 5 (ABHD5\/CGI-58) and adipose triglyceride lipase (ATGL\/PNPLA2) in lipid metabolism and signaling - Lord_2012_Adipocyte_1_123
Author(s) : Lord CC , Brown JM
Ref : Adipocyte , 1 :123 , 2012
PubMedID: 23145367
Gene_locus related to this paper: human-ABHD5

Title : Adipose-selective overexpression of ABHD5\/CGI-58 does not increase lipolysis or protect against diet-induced obesity - Caviglia_2011_J.Lipid.Res_52_2032
Author(s) : Caviglia JM , Betters JL , Dapito DH , Lord CC , Sullivan S , Chua S , Yin T , Sekowski A , Mu H , Shapiro L , Brown JM , Brasaemle DL
Ref : J Lipid Res , 52 :2032 , 2011
PubMedID: 21885429

Title : CGI-58 knockdown in mice causes hepatic steatosis but prevents diet-induced obesity and glucose intolerance - Brown_2010_J.Lipid.Res_51_3306
Author(s) : Brown JM , Betters JL , Lord C , Ma Y , Han X , Yang K , Alger HM , Melchior J , Sawyer J , Shah R , Wilson MD , Liu X , Graham MJ , Lee R , Crooke R , Shulman GI , Xue B , Shi H , Yu L
Ref : J Lipid Res , 51 :3306 , 2010
PubMedID: 20802159
Gene_locus related to this paper: human-ABHD5 , mouse-abhd5

Title : CGI-58 facilitates the mobilization of cytoplasmic triglyceride for lipoprotein secretion in hepatoma cells - Brown_2007_J.Lipid.Res_48_2295
Author(s) : Brown JM , Chung S , Das A , Shelness GS , Rudel LL , Yu L
Ref : J Lipid Res , 48 :2295 , 2007
PubMedID: 17664529