| Title : Deregulation of the endocannabinoid system and therapeutic potential of ABHD6 blockade in the cuprizone model of demyelination - Manterola_2018_Biochem.Pharmacol_157_189 |
| Author(s) : Manterola A , Bernal-Chico A , Cipriani R , Canedo-Antelo M , Moreno-Garcia A , Martin-Fontecha M , Perez-Cerda F , Sanchez-Gomez MV , Ortega-Gutierrez S , Brown JM , Hsu KL , Cravatt B , Matute C , Mato S |
| Ref : Biochemical Pharmacology , 157 :189 , 2018 |
| Abstract : |
| PubMedSearch : Manterola_2018_Biochem.Pharmacol_157_189 |
| PubMedID: 30075103 |
| Gene_locus related to this paper: human-ABHD6 |
| Title : Re-examining the potential of targeting ABHD6 in multiple sclerosis: Efficacy of systemic and peripherally restricted inhibitors in experimental autoimmune encephalomyelitis - Manterola_2018_Neuropharmacol_141_181 |
| Author(s) : Manterola A , Bernal-Chico A , Cipriani R , Ruiz A , Perez-Samartin A , Moreno-Rodriguez M , Hsu KL , Cravatt BF , Brown JM , Rodriguez-Puertas R , Matute C , Mato S |
| Ref : Neuropharmacology , 141 :181 , 2018 |
| Abstract : |
| PubMedSearch : Manterola_2018_Neuropharmacol_141_181 |
| PubMedID: 30171986 |
| Gene_locus related to this paper: human-ABHD6 |
| Title : Regulation of Hepatic Triacylglycerol Metabolism by CGI-58 Does Not Require ATGL Co-activation - Lord_2016_Cell.Rep_16_939 |
| Author(s) : Lord CC , Ferguson D , Thomas G , Brown AL , Schugar RC , Burrows A , Gromovsky AD , Betters J , Neumann C , Sacks J , Marshall S , Watts R , Schweiger M , Lee RG , Crooke RM , Graham MJ , Lathia JD , Sakaguchi TF , Lehner R , Haemmerle G , Zechner R , Brown JM |
| Ref : Cell Rep , 16 :939 , 2016 |
| Abstract : |
| PubMedSearch : Lord_2016_Cell.Rep_16_939 |
| PubMedID: 27396333 |
| Title : An in vivo multiplexed small-molecule screening platform - Gruner_2016_Nat.Methods_13_883 |
| Author(s) : Gruner BM , Schulze CJ , Yang D , Ogasawara D , Dix MM , Rogers ZN , Chuang CH , McFarland CD , Chiou SH , Brown JM , Cravatt BF , Bogyo M , Winslow MM |
| Ref : Nat Methods , 13 :883 , 2016 |
| Abstract : |
| PubMedSearch : Gruner_2016_Nat.Methods_13_883 |
| PubMedID: 27617390 |
| Title : alpha\/beta-Hydrolase Domain 6 Deletion Induces Adipose Browning and Prevents Obesity and Type 2 Diabetes - Zhao_2016_Cell.Rep_14_2872 |
| Author(s) : Zhao S , Mugabo Y , Ballentine G , Attane C , Iglesias J , Poursharifi P , Zhang D , Nguyen TA , Erb H , Prentki R , Peyot ML , Joly E , Tobin S , Fulton S , Brown JM , Madiraju SR , Prentki M |
| Ref : Cell Rep , 14 :2872 , 2016 |
| Abstract : |
| PubMedSearch : Zhao_2016_Cell.Rep_14_2872 |
| PubMedID: 26997277 |
| Gene_locus related to this paper: human-ABHD6 , mouse-ABHD6 |
| Title : alpha\/beta Hydrolase Domain-containing 6 (ABHD6) Degrades the Late Endosomal\/Lysosomal Lipid Bis(monoacylglycero)phosphate - Pribasnig_2015_J.Biol.Chem_290_29869 |
| Author(s) : Pribasnig MA , Mrak I , Grabner GF , Taschler U , Knittelfelder O , Scherz B , Eichmann TO , Heier C , Grumet L , Kowaliuk J , Romauch M , Holler S , Anderl F , Wolinski H , Lass A , Breinbauer R , Marsche G , Brown JM , Zimmermann R |
| Ref : Journal of Biological Chemistry , 290 :29869 , 2015 |
| Abstract : |
| PubMedSearch : Pribasnig_2015_J.Biol.Chem_290_29869 |
| PubMedID: 26491015 |
| Gene_locus related to this paper: human-ABHD6 |
| Title : Hypophagia and metabolic adaptations in mice with defective ATGL-mediated lipolysis cause resistance to HFD-induced obesity - Schreiber_2015_Proc.Natl.Acad.Sci.U.S.A_112_13850 |
| Author(s) : Schreiber R , Hofer P , Taschler U , Voshol PJ , Rechberger GN , Kotzbeck P , Jaeger D , Preiss-Landl K , Lord CC , Brown JM , Haemmerle G , Zimmermann R , Vidal-Puig A , Zechner R |
| Ref : Proc Natl Acad Sci U S A , 112 :13850 , 2015 |
| Abstract : |
| PubMedSearch : Schreiber_2015_Proc.Natl.Acad.Sci.U.S.A_112_13850 |
| PubMedID: 26508640 |
| Title : In vivo metabolite profiling as a means to identify uncharacterized lipase function: Recent success stories within the alpha beta hydrolase domain (ABHD) enzyme family - Thomas_2014_Biochim.Biophys.Acta_1841_1097 |
| Author(s) : Thomas G , Brown AL , Brown JM |
| Ref : Biochimica & Biophysica Acta , 1841 :1097 , 2014 |
| Abstract : |
| PubMedSearch : Thomas_2014_Biochim.Biophys.Acta_1841_1097 |
| PubMedID: 24423940 |
| Gene_locus related to this paper: human-ABHD3 , human-ABHD6 , human-ABHD12 |
| Title : Deletion of CGI-58 or adipose triglyceride lipase differently affects macrophage function and atherosclerosis - Goeritzer_2014_J.Lipid.Res_55_2562 |
| Author(s) : Goeritzer M , Schlager S , Radovic B , Madreiter CT , Rainer S , Thomas G , Lord CC , Sacks J , Brown AL , Vujic N , Obrowsky S , Sachdev V , Kolb D , Chandak PG , Graier WF , Sattler W , Brown JM , Kratky D |
| Ref : J Lipid Res , 55 :2562 , 2014 |
| Abstract : |
| PubMedSearch : Goeritzer_2014_J.Lipid.Res_55_2562 |
| PubMedID: 25316883 |
| Gene_locus related to this paper: mouse-abhd5 |
| Title : Nocardia vulneris sp. nov., isolated from wounds of human patients in North America - Lasker_2014_Antonie.Van.Leeuwenhoek_106_543 |
| Author(s) : Lasker BA , Bell M , Klenk HP , Sproer C , Schumann C , Schumann P , Brown JM |
| Ref : Antonie Van Leeuwenhoek , 106 :543 , 2014 |
| Abstract : |
| PubMedSearch : Lasker_2014_Antonie.Van.Leeuwenhoek_106_543 |
| PubMedID: 25015412 |
| Gene_locus related to this paper: 9noca-k0el65 , 9noca-k0eub3 , 9noca-a0a034u924 , 9noca-a0a0c1b4e1 , 9noca-a0a0c1czw1 , 9noca-a0a0c1d845 , 9noca-a0a0c1cxc1 |
| Title : alpha\/beta-Hydrolase domain-6-accessible monoacylglycerol controls glucose-stimulated insulin secretion - Zhao_2014_Cell.Metab_19_993 |
| Author(s) : Zhao S , Mugabo Y , Iglesias J , Xie L , Delghingaro-Augusto V , Lussier R , Peyot ML , Joly E , Taib B , Davis MA , Brown JM , Abousalham A , Gaisano H , Madiraju SR , Prentki M |
| Ref : Cell Metab , 19 :993 , 2014 |
| Abstract : |
| PubMedSearch : Zhao_2014_Cell.Metab_19_993 |
| PubMedID: 24814481 |
| Title : The serine hydrolase ABHD6 Is a critical regulator of the metabolic syndrome - Thomas_2013_Cell.Rep_5_508 |
| Author(s) : Thomas G , Betters JL , Lord CC , Brown AL , Marshall S , Ferguson D , Sawyer J , Davis MA , Melchior JT , Blume LC , Howlett AC , Ivanova PT , Milne SB , Myers DS , Mrak I , Leber V , Heier C , Taschler U , Blankman JL , Cravatt BF , Lee RG , Crooke RM , Graham MJ , Zimmermann R , Brown HA , Brown JM |
| Ref : Cell Rep , 5 :508 , 2013 |
| Abstract : |
| PubMedSearch : Thomas_2013_Cell.Rep_5_508 |
| PubMedID: 24095738 |
| Gene_locus related to this paper: human-ABHD6 |
| Title : Mammalian alpha beta hydrolase domain (ABHD) proteins: Lipid metabolizing enzymes at the interface of cell signaling and energy metabolism - Lord_2013_Biochim.Biophys.Acta_1831_792 |
| Author(s) : Lord CC , Thomas G , Brown JM |
| Ref : Biochimica & Biophysica Acta , 1831 :792 , 2013 |
| Abstract : |
| PubMedSearch : Lord_2013_Biochim.Biophys.Acta_1831_792 |
| PubMedID: 23328280 |
| Title : Distinct roles for alpha-beta hydrolase domain 5 (ABHD5\/CGI-58) and adipose triglyceride lipase (ATGL\/PNPLA2) in lipid metabolism and signaling - Lord_2012_Adipocyte_1_123 |
| Author(s) : Lord CC , Brown JM |
| Ref : Adipocyte , 1 :123 , 2012 |
| Abstract : |
| PubMedSearch : Lord_2012_Adipocyte_1_123 |
| PubMedID: 23145367 |
| Gene_locus related to this paper: human-ABHD5 |
| Title : CGI-58\/ABHD5-derived signaling lipids regulate systemic inflammation and insulin action - Lord_2012_Diabetes_61_355 |
| Author(s) : Lord CC , Betters JL , Ivanova PT , Milne SB , Myers DS , Madenspacher J , Thomas G , Chung S , Liu M , Davis MA , Lee RG , Crooke RM , Graham MJ , Parks JS , Brasaemle DL , Fessler MB , Brown HA , Brown JM |
| Ref : Diabetes , 61 :355 , 2012 |
| Abstract : |
| PubMedSearch : Lord_2012_Diabetes_61_355 |
| PubMedID: 22228714 |
| Gene_locus related to this paper: human-ABHD5 |
| Title : Adipose-selective overexpression of ABHD5\/CGI-58 does not increase lipolysis or protect against diet-induced obesity - Caviglia_2011_J.Lipid.Res_52_2032 |
| Author(s) : Caviglia JM , Betters JL , Dapito DH , Lord CC , Sullivan S , Chua S , Yin T , Sekowski A , Mu H , Shapiro L , Brown JM , Brasaemle DL |
| Ref : J Lipid Res , 52 :2032 , 2011 |
| Abstract : |
| PubMedSearch : Caviglia_2011_J.Lipid.Res_52_2032 |
| PubMedID: 21885429 |
| Title : CGI-58 knockdown in mice causes hepatic steatosis but prevents diet-induced obesity and glucose intolerance - Brown_2010_J.Lipid.Res_51_3306 |
| Author(s) : Brown JM , Betters JL , Lord C , Ma Y , Han X , Yang K , Alger HM , Melchior J , Sawyer J , Shah R , Wilson MD , Liu X , Graham MJ , Lee R , Crooke R , Shulman GI , Xue B , Shi H , Yu L |
| Ref : J Lipid Res , 51 :3306 , 2010 |
| Abstract : |
| PubMedSearch : Brown_2010_J.Lipid.Res_51_3306 |
| PubMedID: 20802159 |
| Gene_locus related to this paper: human-ABHD5 , mouse-abhd5 |
| Title : CGI-58 facilitates the mobilization of cytoplasmic triglyceride for lipoprotein secretion in hepatoma cells - Brown_2007_J.Lipid.Res_48_2295 |
| Author(s) : Brown JM , Chung S , Das A , Shelness GS , Rudel LL , Yu L |
| Ref : J Lipid Res , 48 :2295 , 2007 |
| Abstract : |
| PubMedSearch : Brown_2007_J.Lipid.Res_48_2295 |
| PubMedID: 17664529 |