| Title : Design, Synthesis, and In Vitro, In Silico and In Cellulo Evaluation of New Pyrimidine and Pyridine Amide and Carbamate Derivatives as Multi-Functional Cholinesterase Inhibitors - Bortolami_2022_Pharmaceuticals.(Basel)_15_ |
| Author(s) : Bortolami M , Pandolfi F , Tudino V , Messore A , Madia VN , De Vita D , Di Santo R , Costi R , Romeo I , Alcaro S , Colone M , Stringaro A , Espargaro A , Sabate R , Scipione L |
| Ref : Pharmaceuticals (Basel) , 15 : , 2022 |
| Abstract : |
| PubMedSearch : Bortolami_2022_Pharmaceuticals.(Basel)_15_ |
| PubMedID: 35745594 |
| Title : Acetylcholinesterase inhibitors for the treatment of Alzheimer's disease - a patent review (2016-present) - Bortolami_2021_Expert.Opin.Ther.Pat__ |
| Author(s) : Bortolami M , Rocco D , Messore A , Di Santo R , Costi R , Madia VN , Scipione L , Pandolfi F |
| Ref : Expert Opin Ther Pat , : , 2021 |
| Abstract : |
| PubMedSearch : Bortolami_2021_Expert.Opin.Ther.Pat__ |
| PubMedID: 33428491 |
| Title : New Pyrimidine and Pyridine Derivatives as Multitarget Cholinesterase Inhibitors: Design, Synthesis, and In Vitro and In Cellulo Evaluation - Bortolami_2021_ACS.Chem.Neurosci__ |
| Author(s) : Bortolami M , Pandolfi F , Tudino V , Messore A , Madia VN , De Vita D , Di Santo R , Costi R , Romeo I , Alcaro S , Colone M , Stringaro A , Espargaro A , Sabate R , Scipione L |
| Ref : ACS Chem Neurosci , : , 2021 |
| Abstract : |
| PubMedSearch : Bortolami_2021_ACS.Chem.Neurosci__ |
| PubMedID: 34652128 |
| Title : New deferiprone derivatives as multi-functional cholinesterase inhibitors: design, synthesis and in vitro evaluation - Bortolami_2020_Eur.J.Med.Chem_198_112350 |
| Author(s) : Bortolami M , Pandolfi F , De Vita D , Carafa C , Messore A , Di Santo R , Feroci M , Costi R , Chiarotto I , Bagetta D , Alcaro S , Colone M , Stringaro A , Scipione L |
| Ref : Eur Journal of Medicinal Chemistry , 198 :112350 , 2020 |
| Abstract : |
| PubMedSearch : Bortolami_2020_Eur.J.Med.Chem_198_112350 |
| PubMedID: 32380385 |
| Title : New pyridine derivatives as inhibitors of acetylcholinesterase and amyloid aggregation - Pandolfi_2017_Eur.J.Med.Chem_141_197 |
| Author(s) : Pandolfi F , De Vita D , Bortolami M , Coluccia A , Di Santo R , Costi R , Andrisano V , Alabiso F , Bergamini C , Fato R , Bartolini M , Scipione L |
| Ref : Eur Journal of Medicinal Chemistry , 141 :197 , 2017 |
| Abstract : |
| PubMedSearch : Pandolfi_2017_Eur.J.Med.Chem_141_197 |
| PubMedID: 29031067 |
| Title : New N,N-dimethylcarbamate inhibitors of acetylcholinesterase: design synthesis and biological evaluation - De Vita_2016_J.Enzyme.Inhib.Med.Chem__1 |
| Author(s) : De Vita D , Pandolfi F , Ornano L , Feroci M , Chiarotto I , Sileno I , Pepi F , Costi R , Di Santo R , Scipione L |
| Ref : J Enzyme Inhib Med Chem , :1 , 2016 |
| Abstract : |
| PubMedSearch : De Vita_2016_J.Enzyme.Inhib.Med.Chem__1 |
| PubMedID: 27594053 |
| Title : Design, synthesis and evaluation of 3,4-dihydroxybenzoic acid derivatives as antioxidants, bio-metal chelating agents and acetylcholinesterase inhibitors - Friggeri_2015_J.Enzyme.Inhib.Med.Chem_30_166 |
| Author(s) : Friggeri L , De Vita D , Pandolfi F , Tortorella S , Costi R , Di Santo R , Scipione L |
| Ref : J Enzyme Inhib Med Chem , 30 :166 , 2015 |
| Abstract : |
| PubMedSearch : Friggeri_2015_J.Enzyme.Inhib.Med.Chem_30_166 |
| PubMedID: 24517367 |
| Title : (Thiazol-2-yl)hydrazone derivatives from acetylpyridines as dual inhibitors of MAO and AChE: synthesis, biological evaluation and molecular modeling studies - D'Ascenzio_2015_J.Enzyme.Inhib.Med.Chem_30_908 |
| Author(s) : D'Ascenzio M , Chimenti P , Gidaro MC , De Monte C , De Vita D , Granese A , Scipione L , Di Santo R , Costa G , Alcaro S , Yanez M , Carradori S |
| Ref : J Enzyme Inhib Med Chem , 30 :908 , 2015 |
| Abstract : |
| PubMedSearch : D'Ascenzio_2015_J.Enzyme.Inhib.Med.Chem_30_908 |
| PubMedID: 25807300 |
| Title : 4-Aminopyridine derivatives with anticholinesterase and antiamnesic activity - Scipione_2008_Bioorg.Med.Chem.Lett_18_309 |
| Author(s) : Scipione L , De Vita D , Musella A , Flammini L , Bertoni S , Barocelli E |
| Ref : Bioorganic & Medicinal Chemistry Lett , 18 :309 , 2008 |
| Abstract : |
| PubMedSearch : Scipione_2008_Bioorg.Med.Chem.Lett_18_309 |
| PubMedID: 18023348 |
| Title : Choline pivaloyl ester strengthened the benefit effects of Tacrine and Galantamine on electroencephalographic and cognitive performances in nucleus basalis magnocellularis-lesioned and aged rats - Rispoli_2006_Pharmacol.Biochem.Behav_84_453 |
| Author(s) : Rispoli V , Marra R , Costa N , Scipione L , Rotiroti D , De Vita D , Liberatore F , Carelli V |
| Ref : Pharmacol Biochem Behav , 84 :453 , 2006 |
| Abstract : |
| PubMedSearch : Rispoli_2006_Pharmacol.Biochem.Behav_84_453 |
| PubMedID: 16859739 |
| Title : Electroencephalographic effects induced by choline pivaloyl esters in scopolamine-treated or nucleus basalis magnocellularis lesioned rats - Rispoli_2004_Pharmacol.Biochem.Behav_78_667 |
| Author(s) : Rispoli V , Rotiroti D , Carelli V , Liberatore F , Scipione L , Marra R , Tortorella S , Di Rienzo B |
| Ref : Pharmacol Biochem Behav , 78 :667 , 2004 |
| Abstract : |
| PubMedSearch : Rispoli_2004_Pharmacol.Biochem.Behav_78_667 |
| PubMedID: 15301920 |
| Title : Molecular modeling and enzymatic studies of the interaction of a choline analogue and acetylcholinesterase - Alcaro_2002_Bioorg.Med.Chem.Lett_12_2899 |
| Author(s) : Alcaro S , Scipione L , Ortuso F , Posca S , Rispoli V , Rotiroti D |
| Ref : Bioorganic & Medicinal Chemistry Lett , 12 :2899 , 2002 |
| Abstract : |
| PubMedSearch : Alcaro_2002_Bioorg.Med.Chem.Lett_12_2899 |
| PubMedID: 12270172 |