| Title : Novel Inhibitory Function of the Rhizomucor miehei Lipase Propeptide and Three-Dimensional Structures of Its Complexes with the Enzyme - Moroz_2019_ACS.Omega_4_9964 |
| Author(s) : Moroz OV , Blagova E , Reiser V , Saikia R , Dalal S , Jorgensen CI , Bhatia VK , Baunsgaard L , Andersen B , Svendsen A , Wilson KS |
| Ref : ACS Omega , 4 :9964 , 2019 |
| Abstract : |
| PubMedSearch : Moroz_2019_ACS.Omega_4_9964 |
| PubMedID: 31460089 |
| Gene_locus related to this paper: rhimi-lipas |
| Title : Direct observation of Thermomyces lanuginosus lipase diffusional states by Single Particle Tracking and their remodeling by mutations and inhibition - Bohr_2019_Sci.Rep_9_16169 |
| Author(s) : Bohr SS , Lund PM , Kallenbach AS , Pinholt H , Thomsen J , Iversen L , Svendsen A , Christensen SM , Hatzakis NS |
| Ref : Sci Rep , 9 :16169 , 2019 |
| Abstract : |
| PubMedSearch : Bohr_2019_Sci.Rep_9_16169 |
| PubMedID: 31700110 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Molecular Modeling Investigation of the Interaction between Humicola insolens Cutinase and SDS Surfactant Suggests a Mechanism for Enzyme Inactivation - Kjolbye_2019_J.Chem.Inf.Model_59_1977 |
| Author(s) : Kjolbye LR , Laustsen A , Vestergaard M , Periole X , De Maria L , Svendsen A , Coletta A , Schiott B |
| Ref : J Chem Inf Model , 59 :1977 , 2019 |
| Abstract : |
| PubMedSearch : Kjolbye_2019_J.Chem.Inf.Model_59_1977 |
| PubMedID: 30844270 |
| Gene_locus related to this paper: humin-cut |
| Title : The effect of mutations in the lid region of Thermomyces lanuginosus lipase on interactions with triglyceride surfaces: A multi-scale simulation study - Willems_2018_Chem.Phys.Lipids_211_4 |
| Author(s) : Willems N , Lelimousin M , Skjold-Jorgensen J , Svendsen A , Sansom MSP |
| Ref : Chemistry & Physic of Lipids , 211 :4 , 2018 |
| Abstract : |
| PubMedSearch : Willems_2018_Chem.Phys.Lipids_211_4 |
| PubMedID: 28818576 |
| Title : Engineered Humicola insolens cutinase for efficient cellulose acetate deacetylation - Shirke_2017_Biotechnol.J_12_ |
| Author(s) : Shirke AN , Butterfoss GL , Saikia R , Basu A , De Maria L , Svendsen A , Gross RA |
| Ref : Biotechnol J , 12 : , 2017 |
| Abstract : |
| PubMedSearch : Shirke_2017_Biotechnol.J_12_ |
| PubMedID: 28488758 |
| Title : Understanding the activation mechanism of Thermomyces lanuginosus lipase using rational design and tryptophan-induced fluorescence quenching - Skjold-Jorgensen_2016_Eur.J.Lipid.Sci.Tech_118_1644 |
| Author(s) : Skjold-Jorgensen, J , Vind J , Svendsen A , Bjerrum MJ |
| Ref : Eur.J.Lipid.Sci.Tech , 118 :1644 , 2016 |
| Abstract : |
| PubMedSearch : Skjold-Jorgensen_2016_Eur.J.Lipid.Sci.Tech_118_1644 |
| PubMedID: |
| Title : Lipases That Activate at High Solvent Polarities - Skjold-Jorgensen_2016_Biochemistry_55_146 |
| Author(s) : Skjold-Jorgensen J , Vind J , Svendsen A , Bjerrum MJ |
| Ref : Biochemistry , 55 :146 , 2016 |
| Abstract : |
| PubMedSearch : Skjold-Jorgensen_2016_Biochemistry_55_146 |
| PubMedID: 26645098 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Controlled lid-opening in Thermomyces lanuginosus lipase- An engineered switch for studying lipase function - Skjold-Jorgensen_2016_Biochim.Biophys.Acta_1865_20 |
| Author(s) : Skjold-Jorgensen J , Vind J , Moroz OV , Blagova E , Bhatia VK , Svendsen A , Wilson KS , Bjerrum MJ |
| Ref : Biochimica & Biophysica Acta , 1865 :20 , 2016 |
| Abstract : |
| PubMedSearch : Skjold-Jorgensen_2016_Biochim.Biophys.Acta_1865_20 |
| PubMedID: 27693248 |
| Gene_locus related to this paper: humla-1lipa |
| Title : The Enzymatic Activity of Lipases Correlates with Polarity-Induced Conformational Changes: A Trp-Induced Quenching Fluorescence Study - Skjold-Jorgensen_2015_Biochemistry_54_4186 |
| Author(s) : Skjold-Jorgensen J , Bhatia VK , Vind J , Svendsen A , Bjerrum MJ , Farrens D |
| Ref : Biochemistry , 54 :4186 , 2015 |
| Abstract : |
| PubMedSearch : Skjold-Jorgensen_2015_Biochemistry_54_4186 |
| PubMedID: 26087334 |
| Title : Promoting protein self-association in non-glycosylated Thermomyces lanuginosus lipase based on crystal lattice contacts - Madsen_2015_Biochim.Biophys.Acta_1854_1914 |
| Author(s) : Madsen JK , Sorensen TR , Kaspersen JD , Silow MB , Vind J , Pedersen JS , Svendsen A , Otzen DE |
| Ref : Biochimica & Biophysica Acta , 1854 :1914 , 2015 |
| Abstract : |
| PubMedSearch : Madsen_2015_Biochim.Biophys.Acta_1854_1914 |
| PubMedID: 26431886 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Thermodynamic and structural investigation of the specific SDS binding of humicola insolens cutinase - Kold_2014_Protein.Sci_23_1023 |
| Author(s) : Kold D , Dauter Z , Laustsen AK , Brzozowski AM , Turkenburg JP , Nielsen AD , Koldso H , Petersen E , Schiott B , De Maria L , Wilson KS , Svendsen A , Wimmer R |
| Ref : Protein Science , 23 :1023 , 2014 |
| Abstract : |
| PubMedSearch : Kold_2014_Protein.Sci_23_1023 |
| PubMedID: 24832484 |
| Gene_locus related to this paper: humin-cut |
| Title : Altering the activation mechanism in Thermomyces lanuginosus lipase - Skjold-Jorgensen_2014_Biochemistry_53_4152 |
| Author(s) : Skjold-Jorgensen J , Vind J , Svendsen A , Bjerrum MJ |
| Ref : Biochemistry , 53 :4152 , 2014 |
| Abstract : |
| PubMedSearch : Skjold-Jorgensen_2014_Biochemistry_53_4152 |
| PubMedID: 24870718 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Variant of the Thermomyces lanuginosus lipase with improved kinetic stability: A candidate for enzyme replacement therapy - Wang_2013_Biophys.Chem_172C_43 |
| Author(s) : Wang H , Hagedorn J , Svendsen A , Borch K , Otzen DE |
| Ref : Biophysical Chemistry , 172C :43 , 2013 |
| Abstract : |
| PubMedSearch : Wang_2013_Biophys.Chem_172C_43 |
| PubMedID: 23357413 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Bioinformatic analysis of alpha\/beta-hydrolase fold enzymes reveals subfamily-specific positions responsible for discrimination of amidase and lipase activities - Suplatov_2012_Protein.Eng.Des.Sel_25_689 |
| Author(s) : Suplatov DA , Besenmatter W , Svedas VK , Svendsen A |
| Ref : Protein Engineering Des Sel , 25 :689 , 2012 |
| Abstract : |
| PubMedSearch : Suplatov_2012_Protein.Eng.Des.Sel_25_689 |
| PubMedID: 23043134 |
| Gene_locus related to this paper: canar-LipB |
| Title : Esterases with an introduced amidase-like hydrogen bond in the transition state have increased amidase specificity - |
| Author(s) : Syren PO , Hendil-Forssell P , Aumailley L , Besenmatter W , Gounine F , Svendsen A , Martinelle M , Hult K |
| Ref : Chembiochem , 13 :645 , 2012 |
| PubMedID: 22378481 |
| Title : Enzymatic activity of lipase-nanoparticle conjugates and the digestion of lipid liquid crystalline assemblies - Brennan_2010_Langmuir_26_13590 |
| Author(s) : Brennan JL , Kanaras AG , Nativo P , Tshikhudo TR , Rees C , Fernandez LC , Dirvianskyte N , Razumas V , Skjot M , Svendsen A , Jorgensen CI , Schweins R , Zackrisson M , Nylander T , Brust M , Barauskas J |
| Ref : Langmuir , 26 :13590 , 2010 |
| Abstract : |
| PubMedSearch : Brennan_2010_Langmuir_26_13590 |
| PubMedID: 20695608 |
| Title : Understanding the plasticity of the alpha\/beta hydrolase fold: lid swapping on the Candida antarctica lipase B results in chimeras with interesting biocatalytic properties - Skjot_2009_Chembiochem_10_520 |
| Author(s) : Skjot M , De Maria L , Chatterjee R , Svendsen A , Patkar SA , Ostergaard PR , Brask J |
| Ref : Chembiochem , 10 :520 , 2009 |
| Abstract : |
| PubMedSearch : Skjot_2009_Chembiochem_10_520 |
| PubMedID: 19156649 |
| Gene_locus related to this paper: canar-LipB |
| Title : Probing of lipase activity at air\/water interface by sum-frequency generation spectroscopy - Niaura_2008_J.Phys.Chem.B_112_4094 |
| Author(s) : Niaura G , Kuprionis Z , Ignatjev I , Kazemekaite M , Valincius G , Talaikyte Z , Razumas V , Svendsen A |
| Ref : J Phys Chem B , 112 :4094 , 2008 |
| Abstract : |
| PubMedSearch : Niaura_2008_J.Phys.Chem.B_112_4094 |
| PubMedID: 18324801 |
| Title : Atomic force microscope visualization of lipid bilayer degradation due to action of phospholipase A2 and Humicola lanuginosa lipase - Balashev_2007_Biochim.Biophys.Acta_1768_90 |
| Author(s) : Balashev K , John DiNardo N , Callisen TH , Svendsen A , Bjornholm T |
| Ref : Biochimica & Biophysica Acta , 1768 :90 , 2007 |
| Abstract : |
| PubMedSearch : Balashev_2007_Biochim.Biophys.Acta_1768_90 |
| PubMedID: 17084807 |
| Title : Synthesis and single enzyme activity of a clicked lipase-BSA hetero-dimer - Hatzakis_2006_Chem.Commun.(Camb)__2012 |
| Author(s) : Hatzakis NS , Engelkamp H , Velonia K , Hofkens J , Christianen PC , Svendsen A , Patkar SA , Vind J , Maan JC , Rowan AE , Nolte RJ |
| Ref : Chem Commun (Camb) , :2012 , 2006 |
| Abstract : |
| PubMedSearch : Hatzakis_2006_Chem.Commun.(Camb)__2012 |
| PubMedID: 16767259 |
| Title : Implications of surface charge and curvature for the binding orientation of Thermomyces lanuginosus lipase on negatively charged or zwitterionic phospholipid vesicles as studied by ESR spectroscopy - Hedin_2005_Biochemistry_44_16658 |
| Author(s) : Hedin EM , Hoyrup P , Patkar SA , Vind J , Svendsen A , Hult K |
| Ref : Biochemistry , 44 :16658 , 2005 |
| Abstract : |
| PubMedSearch : Hedin_2005_Biochemistry_44_16658 |
| PubMedID: 16342956 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Electrochemical method for the detection of lipase activity - Valincius_2005_Anal.Chem_77_2632 |
| Author(s) : Valincius G , Ignatjev I , Niaura G , Kazemekaite M , Talaikyte Z , Razumas V , Svendsen A |
| Ref : Analytical Chemistry , 77 :2632 , 2005 |
| Abstract : |
| PubMedSearch : Valincius_2005_Anal.Chem_77_2632 |
| PubMedID: 15828803 |
| Title : Unfolding and inactivation of cutinases by AOT and guanidine hydrochloride - Ternstrom_2005_Biochim.Biophys.Acta_1748_74 |
| Author(s) : Ternstrom T , Svendsen A , Akke M , Adlercreutz P |
| Ref : Biochimica & Biophysica Acta , 1748 :74 , 2005 |
| Abstract : |
| PubMedSearch : Ternstrom_2005_Biochim.Biophys.Acta_1748_74 |
| PubMedID: 15752695 |
| Gene_locus related to this paper: humin-cut |
| Title : Direct amperometric determination of lipase activity - |
| Author(s) : Ignatjev I , Valincius G , Svedaite I , Gaidamauskas E , Kazemekaite M , Razumas V , Svendsen A |
| Ref : Analytical Biochemistry , 344 :275 , 2005 |
| PubMedID: 16091283 |
| Title : Structure of a feruloyl esterase from Aspergillus niger - McAuley_2004_Acta.Crystallogr.D.Biol.Crystallogr_60_878 |
| Author(s) : McAuley KE , Svendsen A , Patkar SA , Wilson KS |
| Ref : Acta Crystallographica D Biol Crystallogr , 60 :878 , 2004 |
| Abstract : |
| PubMedSearch : McAuley_2004_Acta.Crystallogr.D.Biol.Crystallogr_60_878 |
| PubMedID: 15103133 |
| Gene_locus related to this paper: aspni-FAEA |
| Title : Humicola lanuginosa lipase hydrolysis of mono-oleoyl-rac-glycerol at the lipid-water interface observed by atomic force microscopy - Balashev_2003_Biochim.Biophys.Acta_1615_93 |
| Author(s) : Balashev K , Gudmand M , Iversen L , Callisen TH , Svendsen A , Bjornholm T |
| Ref : Biochimica & Biophysica Acta , 1615 :93 , 2003 |
| Abstract : |
| PubMedSearch : Balashev_2003_Biochim.Biophys.Acta_1615_93 |
| PubMedID: 12948591 |
| Title : Surface fluorescence resonance energy transfer studies on interfacial adsorption of Thermomyces (humicola) lanuginosa lipase, using monomolecular films of cis-parinaric acid - Yapoudjian_2002_Biopolymers_65_121 |
| Author(s) : Yapoudjian S , Ivanova M , Douchet I , Zenatti A , Sentis M , Marine W , Svendsen A , Verger R |
| Ref : Biopolymers , 65 :121 , 2002 |
| Abstract : |
| PubMedSearch : Yapoudjian_2002_Biopolymers_65_121 |
| PubMedID: 12209462 |
| Title : Interfacial orientation of Thermomyces lanuginosa lipase on phospholipid vesicles investigated by electron spin resonance relaxation spectroscopy - Hedin_2002_Biochemistry_41_14185 |
| Author(s) : Hedin EM , Hoyrup P , Patkar SA , Vind J , Svendsen A , Fransson L , Hult K |
| Ref : Biochemistry , 41 :14185 , 2002 |
| Abstract : |
| PubMedSearch : Hedin_2002_Biochemistry_41_14185 |
| PubMedID: 12450382 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Binding of Thermomyces (Humicola) lanuginosa lipase to the mixed micelles of cis-parinaric acid\/NaTDC - Yapoudjian_2002_Eur.J.Biochem_269_1613 |
| Author(s) : Yapoudjian S , Ivanova MG , Brzozowski AM , Patkar SA , Vind J , Svendsen A , Verger R |
| Ref : European Journal of Biochemistry , 269 :1613 , 2002 |
| Abstract : |
| PubMedSearch : Yapoudjian_2002_Eur.J.Biochem_269_1613 |
| PubMedID: 11895431 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Impact of the tryptophan residues of Humicola lanuginosa lipase on its thermal stability - Zhu_2001_Biochim.Biophys.Acta_1547_329 |
| Author(s) : Zhu K , Jutila A , Tuominen EK , Patkar SA , Svendsen A , Kinnunen PK |
| Ref : Biochimica & Biophysica Acta , 1547 :329 , 2001 |
| Abstract : |
| PubMedSearch : Zhu_2001_Biochim.Biophys.Acta_1547_329 |
| PubMedID: 11410289 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Structural origins of the interfacial activation in Thermomyces (Humicola) lanuginosa lipase - Brzozowski_2000_Biochemistry_39_15071 |
| Author(s) : Brzozowski AM , Savage H , Verma CS , Turkenburg JP , Lawson DM , Svendsen A , Patkar S |
| Ref : Biochemistry , 39 :15071 , 2000 |
| Abstract : |
| PubMedSearch : Brzozowski_2000_Biochemistry_39_15071 |
| PubMedID: 11106485 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Lipase protein engineering - |
| Author(s) : Svendsen A |
| Ref : Biochimica & Biophysica Acta , 1543 :223 , 2000 |
| PubMedID: 11150608 |
| Title : Effect of the lipid interface on the catalytic activity and spectroscopic properties of a fungal lipase - Cajal_2000_Biochimie_82_1053 |
| Author(s) : Cajal Y , Svendsen A , De Bolos J , Patkar SA , Alsina MA |
| Ref : Biochimie , 82 :1053 , 2000 |
| Abstract : |
| PubMedSearch : Cajal_2000_Biochimie_82_1053 |
| PubMedID: 11099802 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Detergent-induced conformational changes of Humicola lanuginosa lipase studied by fluorescence spectroscopy - Jutila_2000_Biophys.J_78_1634 |
| Author(s) : Jutila A , Zhu K , Patkar SA , Vind J , Svendsen A , Kinnunen PK |
| Ref : Biophysical Journal , 78 :1634 , 2000 |
| Abstract : |
| PubMedSearch : Jutila_2000_Biophys.J_78_1634 |
| PubMedID: 10692347 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Interfacial control of lid opening in Thermomyces lanuginosa lipase - Cajal_2000_Biochemistry_39_413 |
| Author(s) : Cajal Y , Svendsen A , Girona V , Patkar SA , Alsina MA |
| Ref : Biochemistry , 39 :413 , 2000 |
| Abstract : |
| PubMedSearch : Cajal_2000_Biochemistry_39_413 |
| PubMedID: 10631003 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Active serine involved in the stabilization of the active site loop in the Humicola lanuginosa lipase - Peters_1998_Biochemistry_37_12375 |
| Author(s) : Peters GH , Svendsen A , Langberg H , Vind J , Patkar SA , Toxvaerd S , Kinnunen PK |
| Ref : Biochemistry , 37 :12375 , 1998 |
| Abstract : |
| PubMedSearch : Peters_1998_Biochemistry_37_12375 |
| PubMedID: 9730809 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Theoretical investigation of the dynamics of the active site lid in Rhizomucor miehei lipase - Peters_1996_Biophys.J_71_119 |
| Author(s) : Peters GH , Olsen OH , Svendsen A , Wade RC |
| Ref : Biophysical Journal , 71 :119 , 1996 |
| Abstract : |
| PubMedSearch : Peters_1996_Biophys.J_71_119 |
| PubMedID: 8804595 |
| Title : The role of Glu87 and Trp89 in the lid of Humicola lanuginosa lipase - Martinelle_1996_Protein.Eng_9_519 |
| Author(s) : Martinelle M , Holmquist M , Clausen IG , Patkar S , Svendsen A , Hult K |
| Ref : Protein Engineering , 9 :519 , 1996 |
| Abstract : |
| PubMedSearch : Martinelle_1996_Protein.Eng_9_519 |
| PubMedID: 8862552 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Biochemical properties of cloned lipases from the Pseudomonas family - Svendsen_1995_Biochim.Biophys.Acta_1259_9 |
| Author(s) : Svendsen A , Borch K , Barfoed M , Nielsen TB , Gormsen E , Patkar SA |
| Ref : Biochimica & Biophysica Acta , 1259 :9 , 1995 |
| Abstract : |
| PubMedSearch : Svendsen_1995_Biochim.Biophys.Acta_1259_9 |
| PubMedID: 7492621 |
| Title : Probing a functional role of Glu87 and Trp89 in the lid of Humicola lanuginosa lipase through transesterification reactions in organic solvent - Holmquist_1995_J.Protein.Chem_14_217 |
| Author(s) : Holmquist M , Clausen IG , Patkar S , Svendsen A , Hult K |
| Ref : J Protein Chem , 14 :217 , 1995 |
| Abstract : |
| PubMedSearch : Holmquist_1995_J.Protein.Chem_14_217 |
| PubMedID: 7662109 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Trp89 in the lid of Humicola lanuginosa lipase is important for efficient hydrolysis of tributyrin - Holmquist_1994_Lipids_29_599 |
| Author(s) : Holmquist M , Martinelle M , Clausen IG , Patkar S , Svendsen A , Hult K |
| Ref : Lipids , 29 :599 , 1994 |
| Abstract : |
| PubMedSearch : Holmquist_1994_Lipids_29_599 |
| PubMedID: 7815893 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Theoretical studies of Rhizomucor miehei lipase activation - Norin_1993_Protein.Eng_6_855 |
| Author(s) : Norin M , Olsen O , Svendsen A , Edholm O , Hult K |
| Ref : Protein Engineering , 6 :855 , 1993 |
| Abstract : |
| PubMedSearch : Norin_1993_Protein.Eng_6_855 |
| PubMedID: 8309933 |
| Title : Lipases from Rhizomucor miehei and Humicola lanuginosa: modification of the lid covering the active site alters enantioselectivity - Holmquist_1993_J.Protein.Chem_12_749 |
| Author(s) : Holmquist M , Martinelle M , Berglund P , Clausen IG , Patkar S , Svendsen A , Hult K |
| Ref : J Protein Chem , 12 :749 , 1993 |
| Abstract : |
| PubMedSearch : Holmquist_1993_J.Protein.Chem_12_749 |
| PubMedID: 8136025 |