Humicola insolens (Soft-rot fungus) (Thermomyces insolens) Cutinase (HiC) HiCut
Novozym 51032 Hydrolysis of triglycerides and a variety of molecules containing ester linkages. Specific hydrolytic activity on polyvinyl acetate .Catalyzed Polyester-Polyurethane degradation
Family : Cutinase
Block : X
Position in NCBI Life Tree : Humicola insolens
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Fungi N E > Dikarya N E > Ascomycota N E > saccharomyceta N E > Pezizomycotina N E > leotiomyceta N E > sordariomyceta N E > Sordariomycetes N E > Sordariomycetidae N E > Sordariales N E > Chaetomiaceae N E > Humicola N E > Humicola insolens N EQLGAIENGLE SGSANACPDA ILIFARGSTE PGNMGITVGP ALANGLESHI RNIWIQGVGG PYDAALATNF LPRGTSQANI DEGKRLFALA NQKCPNTPVV AGGYSQGAAL IAAAVSELSG AVKEQVKGVA LFGYTQNLQN RGGIPNYPRE RTKVFCNVGD AVCTGTLIIT PAHLSYTIEA RGEAARFLRD RIRA
Title : Recyclable Enzymatic Hydrolysis with Metal-Organic Framework Stabilized Humicola insolens Cutinase (HiC) for Potential PET Upcycling - Wu_2024_Chem.Bio.Eng_1_798 |
Author(s) : Wu A , Sha F , Su S , Farha OK |
Ref : Chem Bio Eng , 1 :798 , 2024 |
Abstract : |
PubMedSearch : Wu_2024_Chem.Bio.Eng_1_798 |
PubMedID: 39974180 |
Gene_locus related to this paper: humin-cut |
Title : Natural deep eutectic solvents as thermostabilizer for Humicola insolens cutinase - Romano_2023_N.Biotechnol_76_118 |
Author(s) : Romano A , Varriale S , Pezzella C , Totaro G , Andanson JM , Verney V , Sisti L |
Ref : N Biotechnol , 76 :118 , 2023 |
Abstract : |
PubMedSearch : Romano_2023_N.Biotechnol_76_118 |
PubMedID: 37257817 |
Gene_locus related to this paper: humin-cut |
Title : Reaction Pathways for the Enzymatic Degradation of Poly(Ethylene Terephthalate): What Characterizes an Efficient PET-Hydrolase? - Schubert_2022_Chembiochem__e202200516 |
Author(s) : Schubert S , Schaller K , Baath JA , Hunt C , Borch K , Jensen K , Brask J , Westh P |
Ref : Chembiochem , :e202200516 , 2022 |
Abstract : |
PubMedSearch : Schubert_2022_Chembiochem__e202200516 |
PubMedID: 36399069 |
Gene_locus related to this paper: idesa-peth , humin-cut , 9bact-g9by57 , thefu-q6a0i4 |
Title : Cutinase-Catalyzed Polyester-Polyurethane Degradation: Elucidation of the Hydrolysis Mechanism - Di Bisceglie_2022_Polymers.(Basel)_14_411 |
Author(s) : Di Bisceglie F , Quartinello F , Vielnascher R , Guebitz GM , Pellis A |
Ref : Polymers (Basel) , 14 :411 , 2022 |
Abstract : |
PubMedSearch : Di Bisceglie_2022_Polymers.(Basel)_14_411 |
PubMedID: 35160402 |
Gene_locus related to this paper: humin-cut |
Title : Novel efficient enzymatic synthesis of the key-reaction intermediate of PET depolymerization, mono(2-hydroxyethyl terephthalate) - MHET - de Queiros Eugenio_2022_J.Biotechnol__ |
Author(s) : de Queiros Eugenio E , Campisano ISP , Dias AG , de Castro AM , Coelho MAZ , Langone MAP |
Ref : J Biotechnol , : , 2022 |
Abstract : |
PubMedSearch : de Queiros Eugenio_2022_J.Biotechnol__ |
PubMedID: 36063976 |
Gene_locus related to this paper: humin-cut |
Title : Comparison of the enzymatic depolymerization of polyethylene terephthalate and AkestraTM using Humicola insolens cutinase - Aristizabal-Lanza_2022_Frontiers.in.Chemical.Engineering_4_ |
Author(s) : Aristizabal-Lanza L , Mankar SV , Tullberg C , Zhang B , Linares-Pasten JA |
Ref : Frontiers in Chemical Engineering , 4 : , 2022 |
Abstract : |
PubMedSearch : Aristizabal-Lanza_2022_Frontiers.in.Chemical.Engineering_4_ |
PubMedID: |
Gene_locus related to this paper: humin-cut |
Title : Adsorption of enzymes with hydrolytic activity on polyethylene terephthalate - Badino_2021_Enzyme.Microb.Technol_152_109937 |
Author(s) : Badino SF , Baath JA , Borch K , Jensen K , Westh P |
Ref : Enzyme Microb Technol , 152 :109937 , 2021 |
Abstract : |
PubMedSearch : Badino_2021_Enzyme.Microb.Technol_152_109937 |
PubMedID: 34749019 |
Gene_locus related to this paper: idesa-peth , humin-cut , thefu-q6a0i4 |
Title : Enzymatic depolymerization of highly crystalline polyethylene terephthalate enabled in moist-solid reaction mixtures - Kaabel_2021_Proc.Natl.Acad.Sci.U.S.A_118_ |
Author(s) : Kaabel S , Therien JPD , Deschenes CE , Duncan D , Friscic T , Auclair K |
Ref : Proc Natl Acad Sci U S A , 118 : , 2021 |
Abstract : |
PubMedSearch : Kaabel_2021_Proc.Natl.Acad.Sci.U.S.A_118_ |
PubMedID: 34257154 |
Gene_locus related to this paper: humin-cut |
Title : Experimental and mathematical modeling approaches for biocatalytic post-consumer poly(ethylene terephthalate) hydrolysis - de Queiros Eugenio_2021_J.Biotechnol__ |
Author(s) : de Queiros Eugenio E , Campisano ISP , de Castro AM , Coelho MAZ , Langone MAP |
Ref : J Biotechnol , : , 2021 |
Abstract : |
PubMedSearch : de Queiros Eugenio_2021_J.Biotechnol__ |
PubMedID: 34534594 |
Gene_locus related to this paper: humin-cut |
Title : Perspectives on the Role of Enzymatic Biocatalysis for the Degradation of Plastic PET - Magalhaes_2021_Int.J.Mol.Sci_22_11257 |
Author(s) : Magalhaes RP , Cunha JM , Sousa SF |
Ref : Int J Mol Sci , 22 :11257 , 2021 |
Abstract : |
PubMedSearch : Magalhaes_2021_Int.J.Mol.Sci_22_11257 |
PubMedID: 34681915 |
Gene_locus related to this paper: 9entr-EsEstB , 9bact-a0a2h5z9r5 , 9psed-peh , 9actn-h6wx58 , idesa-mheth , idesa-peth , thecd-d1a2h1 , humin-cut , 9acto-d4q9n1 , 9acto-f7ix06 , 9bact-g9by57 , bacsu-lip , bacsu-pnbae , canar-LipB , thela-m4tp71 , psemy-a4y035 , thefu-1831 , thefu-q6a0i4 , strsw-c9zcr8 , fusox-CUT , sacvd-c7mve8 |
Title : Comparative biochemistry of four polyester (PET) hydrolases - Baath_2020_Chembiochem_22_1627 |
Author(s) : Baath JA , Borch K , Jensen K , Brask J , Westh P |
Ref : Chembiochem , 22 :1627 , 2020 |
Abstract : |
PubMedSearch : Baath_2020_Chembiochem_22_1627 |
PubMedID: 33351214 |
Gene_locus related to this paper: idesa-peth , humin-cut , bacsu-pnbae , thefu-q6a0i4 , thefu-q6a0i3 |
Title : Cutinases as stereoselective catalysts: Specific activity and enantioselectivity of cutinases and lipases for menthol and its analogs - Su_2020_Enzyme.Microb.Technol_133_109467 |
Author(s) : Su A , Kiokekli S , Naviwala M , Shirke AN , Pavlidis IV , Gross RA |
Ref : Enzyme Microb Technol , 133 :109467 , 2020 |
Abstract : |
PubMedSearch : Su_2020_Enzyme.Microb.Technol_133_109467 |
PubMedID: 31874689 |
Gene_locus related to this paper: humin-cut , canar-LipB , humla-1lipa , rhimi-lipas |
Title : Enhanced activity towards polyacrylates and poly(vinyl acetate) by site-directed mutagenesis of Humicola insolens cutinase - Su_2020_Int.J.Biol.Macromol_162_1752 |
Author(s) : Su L , Hong R , Kong D , Wu J |
Ref : Int J Biol Macromol , 162 :1752 , 2020 |
Abstract : |
PubMedSearch : Su_2020_Int.J.Biol.Macromol_162_1752 |
PubMedID: 32771512 |
Gene_locus related to this paper: humin-cut |
Title : Molecular Modeling Investigation of the Interaction between Humicola insolens Cutinase and SDS Surfactant Suggests a Mechanism for Enzyme Inactivation - Kjolbye_2019_J.Chem.Inf.Model_59_1977 |
Author(s) : Kjolbye LR , Laustsen A , Vestergaard M , Periole X , De Maria L , Svendsen A , Coletta A , Schiott B |
Ref : J Chem Inf Model , 59 :1977 , 2019 |
Abstract : |
PubMedSearch : Kjolbye_2019_J.Chem.Inf.Model_59_1977 |
PubMedID: 30844270 |
Gene_locus related to this paper: humin-cut |
Title : A novel process for poly(ethylene terephthalate) depolymerization via enzyme-catalyzed glycolysis - Machado de Castro_2017_Biochem.Eng.J_124_64 |
Author(s) : Machado de Castro A , Carniel A |
Ref : Biochem Eng J , 124 :64 , 2017 |
Abstract : |
PubMedSearch : Machado de Castro_2017_Biochem.Eng.J_124_64 |
PubMedID: |
Gene_locus related to this paper: humin-cut , canar-LipB |
Title : Substrate specificities of cutinases on aliphatic-aromatic polyesters and on their model substrates - Perz_2016_N.Biotechnol_33_295 |
Author(s) : Perz V , Bleymaier K , Sinkel C , Kueper U , Bonnekessel M , Ribitsch D , Guebitz GM |
Ref : N Biotechnol , 33 :295 , 2016 |
Abstract : |
PubMedSearch : Perz_2016_N.Biotechnol_33_295 |
PubMedID: 26594021 |
Gene_locus related to this paper: humin-cut , thefu-q6a0i4 |
Title : Thermodynamic and structural investigation of the specific SDS binding of humicola insolens cutinase - Kold_2014_Protein.Sci_23_1023 |
Author(s) : Kold D , Dauter Z , Laustsen AK , Brzozowski AM , Turkenburg JP , Nielsen AD , Koldso H , Petersen E , Schiott B , De Maria L , Wilson KS , Svendsen A , Wimmer R |
Ref : Protein Science , 23 :1023 , 2014 |
Abstract : |
PubMedSearch : Kold_2014_Protein.Sci_23_1023 |
PubMedID: 24832484 |
Gene_locus related to this paper: humin-cut |
Title : Two novel class II hydrophobins from Trichoderma spp. stimulate enzymatic hydrolysis of poly(ethylene terephthalate) when expressed as fusion proteins - Espino-Rammer_2013_Appl.Environ.Microbiol_79_4230 |
Author(s) : Espino-Rammer L , Ribitsch D , Przylucka A , Marold A , Greimel KJ , Herrero Acero E , Guebitz GM , Kubicek CP , Druzhinina IS |
Ref : Applied Environmental Microbiology , 79 :4230 , 2013 |
Abstract : |
PubMedSearch : Espino-Rammer_2013_Appl.Environ.Microbiol_79_4230 |
PubMedID: 23645195 |
Gene_locus related to this paper: humin-cut |
Title : Thiol-functionalization of acrylic ester monomers catalyzed by immobilized Humicola insolens cutinase - Kazenwadel_2012_Enzyme.Microb.Technol_51_9 |
Author(s) : Kazenwadel C , Eiben S , Maurer S , Beuttler H , Wetzl D , Hauer B , Koschorreck K |
Ref : Enzyme Microb Technol , 51 :9 , 2012 |
Abstract : |
PubMedSearch : Kazenwadel_2012_Enzyme.Microb.Technol_51_9 |
PubMedID: 22579385 |
Gene_locus related to this paper: humin-cut |
Title : Identification and comparison of cutinases for synthetic polyester degradation - Baker_2012_Appl.Microbiol.Biotechnol_93_229 |
Author(s) : Baker PJ , Poultney C , Liu Z , Gross R , Montclare JK |
Ref : Applied Microbiology & Biotechnology , 93 :229 , 2012 |
Abstract : |
PubMedSearch : Baker_2012_Appl.Microbiol.Biotechnol_93_229 |
PubMedID: 21713515 |
Gene_locus related to this paper: humin-cut |
Title : Substrate conformations set the rate of enzymatic acrylation by lipases - Syren_2010_Chembiochem_11_802 |
Author(s) : Syren PO , Hult K |
Ref : Chembiochem , 11 :802 , 2010 |
Abstract : |
PubMedSearch : Syren_2010_Chembiochem_11_802 |
PubMedID: 20301160 |
Gene_locus related to this paper: humin-cut |
Title : Cutinase-catalyzed hydrolysis of poly(ethylene terephthalate) - Ronkvist_2009_Macromolecules_42_4632 |
Author(s) : Ronkvist AM , Xie W , Lu W , Gross RA |
Ref : Macromolecules , 42 :5128 , 2009 |
Abstract : |
PubMedSearch : Ronkvist_2009_Macromolecules_42_4632 |
PubMedID: |
Gene_locus related to this paper: humin-cut , canar-LipB , fusso-cutas , psemy-a4y035 |
Title : Humicola insolens cutinase-catalyzed lactone ring-opening polymerizations: kinetic and mechanistic studies - Hunsen_2008_Biomacromolecules_9_518 |
Author(s) : Hunsen M , Abul A , Xie W , Gross R |
Ref : Biomacromolecules , 9 :518 , 2008 |
Abstract : |
PubMedSearch : Hunsen_2008_Biomacromolecules_9_518 |
PubMedID: 18198834 |
Gene_locus related to this paper: humin-cut |
Title : Thermal stability of Humicola insolens cutinase in aqueous SDS - Nielsen_2007_J.Phys.Chem.B_111_2941 |
Author(s) : Nielsen AD , Borch K , Westh P |
Ref : J Phys Chem B , 111 :2941 , 2007 |
Abstract : |
PubMedSearch : Nielsen_2007_J.Phys.Chem.B_111_2941 |
PubMedID: 17319710 |
Gene_locus related to this paper: humin-cut |
Title : Analysis of protein-surfactant interactions--a titration calorimetric and fluorescence spectroscopic investigation of interactions between Humicola insolens cutinase and an anionic surfactant - Nielsen_2005_Biochim.Biophys.Acta_1752_124 |
Author(s) : Nielsen AD , Arleth L , Westh P |
Ref : Biochimica & Biophysica Acta , 1752 :124 , 2005 |
Abstract : |
PubMedSearch : Nielsen_2005_Biochim.Biophys.Acta_1752_124 |
PubMedID: 16162423 |
Gene_locus related to this paper: humin-cut |
Title : Interactions of Humicola insolens cutinase with an anionic surfactant studied by small-angle neutron scattering and isothermal titration calorimetry - Nielsen_2005_Langmuir_21_4299 |
Author(s) : Nielsen AD , Arleth L , Westh P |
Ref : Langmuir , 21 :4299 , 2005 |
Abstract : |
PubMedSearch : Nielsen_2005_Langmuir_21_4299 |
PubMedID: 16032839 |
Gene_locus related to this paper: humin-cut |
Title : Unfolding and inactivation of cutinases by AOT and guanidine hydrochloride - Ternstrom_2005_Biochim.Biophys.Acta_1748_74 |
Author(s) : Ternstrom T , Svendsen A , Akke M , Adlercreutz P |
Ref : Biochimica & Biophysica Acta , 1748 :74 , 2005 |
Abstract : |
PubMedSearch : Ternstrom_2005_Biochim.Biophys.Acta_1748_74 |
PubMedID: 15752695 |
Gene_locus related to this paper: humin-cut |