| Title : Inhibition of triple negative breast cancer-associated inflammation, tumor growth and brain colonization by targeting monoacylglycerol lipase - Benchama_2022_Sci.Rep_12_5328 |
| Author(s) : Benchama O , Tyukhtenko S , Malamas MS , Williams MK , Makriyannis A , Avraham HK |
| Ref : Sci Rep , 12 :5328 , 2022 |
| Abstract : |
| PubMedSearch : Benchama_2022_Sci.Rep_12_5328 |
| PubMedID: 35351947 |
| Gene_locus related to this paper: human-MGLL |
| Title : Conformational gating, dynamics and allostery in human monoacylglycerol lipase - Tyukhtenko_2020_Sci.Rep_10_18531 |
| Author(s) : Tyukhtenko S , Ma X , Rajarshi G , Karageorgos I , Anderson KW , Hudgens JW , Guo JJ , Nasr ML , Zvonok N , Vemuri K , Wagner G , Makriyannis A |
| Ref : Sci Rep , 10 :18531 , 2020 |
| Abstract : |
| PubMedSearch : Tyukhtenko_2020_Sci.Rep_10_18531 |
| PubMedID: 33116203 |
| Gene_locus related to this paper: human-MGLL |
| Title : Synthesis and evaluation of potent and selective MGL inhibitors as a glaucoma treatment - Alapafuja_2019_Bioorg.Med.Chem_27_55 |
| Author(s) : Alapafuja SO , Malamas MS , Shukla V , Zvonok A , Miller S , Daily L , Rajarshi G , Miyabe CY , Chandrashekhar H , Wood J , Tyukhtenko S , Straiker A , Makriyannis A |
| Ref : Bioorganic & Medicinal Chemistry , 27 :55 , 2019 |
| Abstract : |
| PubMedSearch : Alapafuja_2019_Bioorg.Med.Chem_27_55 |
| PubMedID: 30446439 |
| Title : Effects of Distal Mutations on the Structure, Dynamics and Catalysis of Human Monoacylglycerol Lipase - Tyukhtenko_2018_Sci.Rep_8_1719 |
| Author(s) : Tyukhtenko S , Rajarshi G , Karageorgos I , Zvonok N , Gallagher ES , Huang H , Vemuri K , Hudgens JW , Ma X , Nasr ML , Pavlopoulos S , Makriyannis A |
| Ref : Sci Rep , 8 :1719 , 2018 |
| Abstract : |
| PubMedSearch : Tyukhtenko_2018_Sci.Rep_8_1719 |
| PubMedID: 29379013 |
| Gene_locus related to this paper: human-MGLL |
| Title : Specific Inter-residue Interactions as Determinants of Human Monoacylglycerol Lipase Catalytic Competency: A ROLE FOR GLOBAL CONFORMATIONAL CHANGES - Tyukhtenko_2016_J.Biol.Chem_291_2556 |
| Author(s) : Tyukhtenko S , Karageorgos I , Rajarshi G , Zvonok N , Pavlopoulos S , Janero DR , Makriyannis A |
| Ref : Journal of Biological Chemistry , 291 :2556 , 2016 |
| Abstract : |
| PubMedSearch : Tyukhtenko_2016_J.Biol.Chem_291_2556 |
| PubMedID: 26555264 |
| Title : Identification by nuclear magnetic resonance spectroscopy of an active-site hydrogen-bond network in human monoacylglycerol lipase (hMGL): implications for hMGL dynamics, pharmacological inhibition, and catalytic mechanism - Karageorgos_2010_Mol.Biosyst_6_1381 |
| Author(s) : Karageorgos I , Tyukhtenko S , Zvonok N , Janero DR , Sallum C , Makriyannis A |
| Ref : Mol Biosyst , 6 :1381 , 2010 |
| Abstract : |
| PubMedSearch : Karageorgos_2010_Mol.Biosyst_6_1381 |
| PubMedID: 20464001 |