Zvonok N

References (14)

Title : Design and Synthesis of Highly Potent and Specific ABHD6 Inhibitors - Malamas_2021_ChemMedChem__
Author(s) : Malamas MS , Lamani M , Farah SI , Mohammad KA , Miyabe CY , Rajarshi G , Wu S , Zvonok N , Chandrashekhar H , Wood J , Makriyannis A
Ref : ChemMedChem , : , 2021
PubMedID: 34486233
Gene_locus related to this paper: human-ABHD6 , mouse-ABHD6

Title : 1-, 2- and 3-AG as substrates of the endocannabinoid enzymes and endogenous ligands of the cannabinoid receptor 1 - Farah_2021_Biochem.Biophys.Res.Commun_591_31
Author(s) : Farah SI , Hilston S , Tran N , Zvonok N , Makriyannis A
Ref : Biochemical & Biophysical Research Communications , 591 :31 , 2021
PubMedID: 34995983
Gene_locus related to this paper: human-ABHD6 , human-MGLL

Title : Conformational gating, dynamics and allostery in human monoacylglycerol lipase - Tyukhtenko_2020_Sci.Rep_10_18531
Author(s) : Tyukhtenko S , Ma X , Rajarshi G , Karageorgos I , Anderson KW , Hudgens JW , Guo JJ , Nasr ML , Zvonok N , Vemuri K , Wagner G , Makriyannis A
Ref : Sci Rep , 10 :18531 , 2020
PubMedID: 33116203
Gene_locus related to this paper: human-MGLL

Title : Biochemical and Proteomic Characterization of Recombinant Human alpha\/beta Hydrolase Domain 6 - Shields_2019_Sci.Rep_9_890
Author(s) : Shields CM , Zvonok N , Zvonok A , Makriyannis A
Ref : Sci Rep , 9 :890 , 2019
PubMedID: 30696836
Gene_locus related to this paper: human-ABHD6

Title : ( R)- N-(1-Methyl-2-hydroxyethyl)-13-( S)-methyl-arachidonamide (AMG315): A Novel Chiral Potent Endocannabinoid Ligand with Stability to Metabolizing Enzymes - Liu_2018_J.Med.Chem_61_8639
Author(s) : Liu Y , Ji L , Eno M , Kudalkar S , Li AL , Schimpgen M , Benchama O , Morales P , Xu S , Hurst D , Wu S , Mohammad KA , Wood JT , Zvonok N , Papahatjis DP , Zhou H , Honrao C , Mackie K , Reggio P , Hohmann AG , Marnett LJ , Makriyannis A , Nikas SP
Ref : Journal of Medicinal Chemistry , 61 :8639 , 2018
PubMedID: 30196704

Title : Effects of Distal Mutations on the Structure, Dynamics and Catalysis of Human Monoacylglycerol Lipase - Tyukhtenko_2018_Sci.Rep_8_1719
Author(s) : Tyukhtenko S , Rajarshi G , Karageorgos I , Zvonok N , Gallagher ES , Huang H , Vemuri K , Hudgens JW , Ma X , Nasr ML , Pavlopoulos S , Makriyannis A
Ref : Sci Rep , 8 :1719 , 2018
PubMedID: 29379013
Gene_locus related to this paper: human-MGLL

Title : The role of human monoacylglycerol lipase (hMAGL) binding pocket in breakup of unsaturated phospholipid membranes - Karageorgos_2017_Anal.Biochem_536_90
Author(s) : Karageorgos I , Silin VI , Zvonok N , Marino J , Janero DR , Makriyannis A
Ref : Analytical Biochemistry , 536 :90 , 2017
PubMedID: 28822686
Gene_locus related to this paper: human-MGLL

Title : Specific Inter-residue Interactions as Determinants of Human Monoacylglycerol Lipase Catalytic Competency: A ROLE FOR GLOBAL CONFORMATIONAL CHANGES - Tyukhtenko_2016_J.Biol.Chem_291_2556
Author(s) : Tyukhtenko S , Karageorgos I , Rajarshi G , Zvonok N , Pavlopoulos S , Janero DR , Makriyannis A
Ref : Journal of Biological Chemistry , 291 :2556 , 2016
PubMedID: 26555264

Title : Active-site inhibitors modulate the dynamic properties of human monoacylglycerol lipase: a hydrogen exchange mass spectrometry study - Karageorgos_2013_Biochemistry_52_5016
Author(s) : Karageorgos I , Wales TE , Janero DR , Zvonok N , Vemuri VK , Engen JR , Makriyannis A
Ref : Biochemistry , 52 :5016 , 2013
PubMedID: 23795559

Title : Membrane phospholipid bilayer as a determinant of monoacylglycerol lipase kinetic profile and conformational repertoire - Nasr_2013_Protein.Sci_22_774
Author(s) : Nasr ML , Shi X , Bowman AL , Johnson M , Zvonok N , Janero DR , Vemuri VK , Wales TE , Engen JR , Makriyannis A
Ref : Protein Science , 22 :774 , 2013
PubMedID: 23553709

Title : Endocannabinoid enzyme engineering: soluble human thio-monoacylglycerol lipase (sol-S-hMGL) - Karageorgos_2012_ACS.Chem.Neurosci_3_393
Author(s) : Karageorgos I , Zvonok N , Janero DR , Vemuri VK , Shukla V , Wales TE , Engen JR , Makriyannis A
Ref : ACS Chem Neurosci , 3 :393 , 2012
PubMedID: 22860208
Gene_locus related to this paper: human-MGLL

Title : Identification by nuclear magnetic resonance spectroscopy of an active-site hydrogen-bond network in human monoacylglycerol lipase (hMGL): implications for hMGL dynamics, pharmacological inhibition, and catalytic mechanism - Karageorgos_2010_Mol.Biosyst_6_1381
Author(s) : Karageorgos I , Tyukhtenko S , Zvonok N , Janero DR , Sallum C , Makriyannis A
Ref : Mol Biosyst , 6 :1381 , 2010
PubMedID: 20464001

Title : Full mass spectrometric characterization of human monoacylglycerol lipase generated by large-scale expression and single-step purification - Zvonok_2008_J.Proteome.Res_7_2158
Author(s) : Zvonok N , Williams J , Johnston M , Pandarinathan L , Janero DR , Li J , Krishnan SC , Makriyannis A
Ref : J Proteome Res , 7 :2158 , 2008
PubMedID: 18452279

Title : Covalent inhibitors of human monoacylglycerol lipase: ligand-assisted characterization of the catalytic site by mass spectrometry and mutational analysis - Zvonok_2008_Chem.Biol_15_854
Author(s) : Zvonok N , Pandarinathan L , Williams J , Johnston M , Karageorgos I , Janero DR , Krishnan SC , Makriyannis A
Ref : Chemical Biology , 15 :854 , 2008
PubMedID: 18721756