| Title : Conformational gating, dynamics and allostery in human monoacylglycerol lipase - Tyukhtenko_2020_Sci.Rep_10_18531 |
| Author(s) : Tyukhtenko S , Ma X , Rajarshi G , Karageorgos I , Anderson KW , Hudgens JW , Guo JJ , Nasr ML , Zvonok N , Vemuri K , Wagner G , Makriyannis A |
| Ref : Sci Rep , 10 :18531 , 2020 |
| Abstract : |
| PubMedSearch : Tyukhtenko_2020_Sci.Rep_10_18531 |
| PubMedID: 33116203 |
| Gene_locus related to this paper: human-MGLL |
| Title : Effects of Distal Mutations on the Structure, Dynamics and Catalysis of Human Monoacylglycerol Lipase - Tyukhtenko_2018_Sci.Rep_8_1719 |
| Author(s) : Tyukhtenko S , Rajarshi G , Karageorgos I , Zvonok N , Gallagher ES , Huang H , Vemuri K , Hudgens JW , Ma X , Nasr ML , Pavlopoulos S , Makriyannis A |
| Ref : Sci Rep , 8 :1719 , 2018 |
| Abstract : |
| PubMedSearch : Tyukhtenko_2018_Sci.Rep_8_1719 |
| PubMedID: 29379013 |
| Gene_locus related to this paper: human-MGLL |
| Title : The role of human monoacylglycerol lipase (hMAGL) binding pocket in breakup of unsaturated phospholipid membranes - Karageorgos_2017_Anal.Biochem_536_90 |
| Author(s) : Karageorgos I , Silin VI , Zvonok N , Marino J , Janero DR , Makriyannis A |
| Ref : Analytical Biochemistry , 536 :90 , 2017 |
| Abstract : |
| PubMedSearch : Karageorgos_2017_Anal.Biochem_536_90 |
| PubMedID: 28822686 |
| Gene_locus related to this paper: human-MGLL |
| Title : Specific Inter-residue Interactions as Determinants of Human Monoacylglycerol Lipase Catalytic Competency: A ROLE FOR GLOBAL CONFORMATIONAL CHANGES - Tyukhtenko_2016_J.Biol.Chem_291_2556 |
| Author(s) : Tyukhtenko S , Karageorgos I , Rajarshi G , Zvonok N , Pavlopoulos S , Janero DR , Makriyannis A |
| Ref : Journal of Biological Chemistry , 291 :2556 , 2016 |
| Abstract : |
| PubMedSearch : Tyukhtenko_2016_J.Biol.Chem_291_2556 |
| PubMedID: 26555264 |
| Title : Active-site inhibitors modulate the dynamic properties of human monoacylglycerol lipase: a hydrogen exchange mass spectrometry study - Karageorgos_2013_Biochemistry_52_5016 |
| Author(s) : Karageorgos I , Wales TE , Janero DR , Zvonok N , Vemuri VK , Engen JR , Makriyannis A |
| Ref : Biochemistry , 52 :5016 , 2013 |
| Abstract : |
| PubMedSearch : Karageorgos_2013_Biochemistry_52_5016 |
| PubMedID: 23795559 |
| Title : Endocannabinoid enzyme engineering: soluble human thio-monoacylglycerol lipase (sol-S-hMGL) - Karageorgos_2012_ACS.Chem.Neurosci_3_393 |
| Author(s) : Karageorgos I , Zvonok N , Janero DR , Vemuri VK , Shukla V , Wales TE , Engen JR , Makriyannis A |
| Ref : ACS Chem Neurosci , 3 :393 , 2012 |
| Abstract : |
| PubMedSearch : Karageorgos_2012_ACS.Chem.Neurosci_3_393 |
| PubMedID: 22860208 |
| Gene_locus related to this paper: human-MGLL |
| Title : Identification by nuclear magnetic resonance spectroscopy of an active-site hydrogen-bond network in human monoacylglycerol lipase (hMGL): implications for hMGL dynamics, pharmacological inhibition, and catalytic mechanism - Karageorgos_2010_Mol.Biosyst_6_1381 |
| Author(s) : Karageorgos I , Tyukhtenko S , Zvonok N , Janero DR , Sallum C , Makriyannis A |
| Ref : Mol Biosyst , 6 :1381 , 2010 |
| Abstract : |
| PubMedSearch : Karageorgos_2010_Mol.Biosyst_6_1381 |
| PubMedID: 20464001 |
| Title : Covalent inhibitors of human monoacylglycerol lipase: ligand-assisted characterization of the catalytic site by mass spectrometry and mutational analysis - Zvonok_2008_Chem.Biol_15_854 |
| Author(s) : Zvonok N , Pandarinathan L , Williams J , Johnston M , Karageorgos I , Janero DR , Krishnan SC , Makriyannis A |
| Ref : Chemical Biology , 15 :854 , 2008 |
| Abstract : |
| PubMedSearch : Zvonok_2008_Chem.Biol_15_854 |
| PubMedID: 18721756 |