| Title : Generation and validation of a novel multitarget small molecule in glioblastoma - Artetxe-Zurutuza_2025_Cell.Death.Dis_16_250 |
| Author(s) : Artetxe-Zurutuza A , Iturrioz-Rodriguez N , Elizazu J , Toledano-Pinedo M , Porro-Perez A , De Goni I , Elua-Pinin A , Schaker-Hubner L , Azkargorta M , Elortza F , Iriepa I , Lopez-Munoz F , Moncho-Amor V , Hansen FK , Sampron N , Marco-Contelles JL , Matheu A |
| Ref : Cell Death Dis , 16 :250 , 2025 |
| Abstract : |
| PubMedSearch : Artetxe-Zurutuza_2025_Cell.Death.Dis_16_250 |
| PubMedID: 40185715 |
| Title : 2-{N-[-(1-Benzylpiperidin-4-yl)alkyl]amino}-6-[(prop-2-yn-1-yl)amino]pyridine-3,5-dicarbonitriles Showing High Affinity for (1\/2) Receptors - Deuther-Conrad_2025_Int.J.Mol.Sci_26_ |
| Author(s) : Deuther-Conrad W , Schepmann D , Iriepa I , Lopez-Munoz F , Chioua M , Wunsch B , Samadi A , Marco-Contelles J |
| Ref : Int J Mol Sci , 26 : , 2025 |
| Abstract : |
| PubMedSearch : Deuther-Conrad_2025_Int.J.Mol.Sci_26_ |
| PubMedID: 39941036 |
| Title : Contilistat, a new polyfunctionalized histone deacetylase inhibitor, showing potential capacity to inhibit cholinesterase\/monoamine oxidase enzymes, and modulate histamine 3, sigma 1, 5-HT6 and dopamine 3 receptors for the treatment of cancer and neurodegenerative diseases - Diez-Iriepa_2023_Chemrxiv__ |
| Author(s) : Diez-Iriepa D , Toledano-Pinedo M , Porro A , Almendros P , Rodriguez-Fernandez, MM , Samadi A , Iriepa I , Lopez-Munoz F , Artetxe-Zurutuza A , Matheu A , Marco-Contelles J |
| Ref : Chemrxiv , : , 2023 |
| Abstract : |
| PubMedSearch : Diez-Iriepa_2023_Chemrxiv__ |
| PubMedID: |
| Title : 8-Hydroxyquinolylnitrones as multifunctional ligands for the therapy of neurodegenerative diseases - Knez_2023_Acta.Pharmaceutica.Sinica.B_13_2152 |
| Author(s) : Knez D , Diez-Iriepa D , Chioua M , Gottinger A , Denic M , Chantegreil F , Nachon F , Brazzolotto X , Skrzypczak-Wiercioch A , Meden A , Pislar A , Kos J , Zakelj S , Stojan J , Salat K , Serrano J , Patricia Fernandez AP , Sanchez-Garcia A , Martinez-Murillo R , Binda C , Lopez-Munoz F , Gobec S , Marco-Contelles J |
| Ref : Acta Pharmaceutica Sinica B , 13 :2152 , 2023 |
| Abstract : |
| PubMedSearch : Knez_2023_Acta.Pharmaceutica.Sinica.B_13_2152 |
| PubMedID: 37250172 |
| Gene_locus related to this paper: human-BCHE |
| Title : Polyfunctionalized alpha-Phenyl-tert-butyl(benzyl)nitrones: Multifunctional Antioxidants for Stroke Treatment - Diez-Iriepa_2022_Antioxidants.(Basel)_11_ |
| Author(s) : Diez-Iriepa D , Knez D , Gobec S , Iriepa I , de los Rios C , Bravo I , Lopez-Munoz F , Marco-Contelles J , Hadjipavlou-Litina D |
| Ref : Antioxidants (Basel) , 11 : , 2022 |
| Abstract : |
| PubMedSearch : Diez-Iriepa_2022_Antioxidants.(Basel)_11_ |
| PubMedID: 36139811 |
| Title : The Chemotype of Chromanones as a Privileged Scaffold for Multineurotarget Anti-Alzheimer Agents - Keuler_2022_ACS.Pharmacol.Transl.Sci_5_1097 |
| Author(s) : Keuler T , Lemke C , Elsinghorst PW , Iriepa I , Chioua M , Martinez-Grau MA , Beadle CD , Vetman T , Lopez-Munoz F , Wille T , Bartz U , Deuther-Conrad W , Marco-Contelles J , Gutschow M |
| Ref : ACS Pharmacol Transl Sci , 5 :1097 , 2022 |
| Abstract : |
| PubMedSearch : Keuler_2022_ACS.Pharmacol.Transl.Sci_5_1097 |
| PubMedID: 36407962 |
| Title : Studies on the affinity of 6-[(n-(cyclo)aminoalkyl)oxy]-4H-chromen-4-ones for sigma 1\/2 receptors - Deuther-Conrad_2021_RSC.Med.Chem_12_1000 |
| Author(s) : Deuther-Conrad W , Diez-Iriepa D , Iriepa I , Lopez-Munoz F , Martinez-Grau MA , Gutschow M , Marco-Contelles J |
| Ref : RSC Med Chem , 12 :1000 , 2021 |
| Abstract : |
| PubMedSearch : Deuther-Conrad_2021_RSC.Med.Chem_12_1000 |
| PubMedID: 34223165 |
| Title : Acetylcholinesterase Inhibition of Diversely Functionalized Quinolinones for Alzheimer's Disease Therapy - Bautista-Aguilera_2020_Int.J.Mol.Sci_21_ |
| Author(s) : Bautista-Aguilera OM , Ismaili L , Chioua M , Andrys R , Schmidt M , Bzonek P , Martinez-Grau MA , Beadle CD , Vetman T , Lopez-Munoz F , Iriepa I , Refouvelet B , Musilek K , Marco-Contelles J |
| Ref : Int J Mol Sci , 21 : , 2020 |
| Abstract : |
| PubMedSearch : Bautista-Aguilera_2020_Int.J.Mol.Sci_21_ |
| PubMedID: 32486316 |
| Title : Contilisant, a Tetratarget Small Molecule for Alzheimer's Disease Therapy Combining Cholinesterase, Monoamine Oxidase Inhibition, and H3R Antagonism with S1R Agonism Profile - Bautista-Aguilera_2018_J.Med.Chem_61_6937 |
| Author(s) : Bautista-Aguilera OM , Budni J , Mina F , Medeiros EB , Deuther-Conrad W , Entrena JM , Moraleda I , Iriepa I , Lopez-Munoz F , Marco-Contelles J |
| Ref : Journal of Medicinal Chemistry , 61 :6937 , 2018 |
| Abstract : |
| PubMedSearch : Bautista-Aguilera_2018_J.Med.Chem_61_6937 |
| PubMedID: 29969030 |
| Title : Multitarget-Directed Ligands Combining Cholinesterase and Monoamine Oxidase Inhibition with Histamine H3 R Antagonism for Neurodegenerative Diseases - Bautista-Aguilera_2017_Angew.Chem.Int.Ed.Engl_56_12765 |
| Author(s) : Bautista-Aguilera OM , Hagenow S , Palomino-Antolin A , Farre-Alins V , Ismaili L , Joffrin PL , Jimeno ML , Soukup O , Janockova J , Kalinowsky L , Proschak E , Iriepa I , Moraleda I , Schwed JS , Romero Martinez A , Lopez-Munoz F , Chioua M , Egea J , Ramsay RR , Marco-Contelles J , Stark H |
| Ref : Angew Chem Int Ed Engl , 56 :12765 , 2017 |
| Abstract : |
| PubMedSearch : Bautista-Aguilera_2017_Angew.Chem.Int.Ed.Engl_56_12765 |
| PubMedID: 28861918 |
| Title : [The development of neurotoxic agents as chemical weapons during the National Socialist period in Germany] - Lopez-Munoz_2008_Rev.Neurol_47_99 |
| Author(s) : Lopez-Munoz F , Alamo C , Guerra JA , Garcia-Garcia P |
| Ref : Rev Neurol , 47 :99 , 2008 |
| Abstract : |
| PubMedSearch : Lopez-Munoz_2008_Rev.Neurol_47_99 |
| PubMedID: 18623009 |