| Title : Tumor-targeted enzyme\/prodrug therapy mediates long-term disease-free survival of mice bearing disseminated neuroblastoma - Danks_2007_Cancer.Res_67_22 |
| Author(s) : Danks MK , Yoon KJ , Bush RA , Remack JS , Wierdl M , Tsurkan L , Kim SU , Garcia E , Metz MZ , Najbauer J , Potter PM , Aboody KS |
| Ref : Cancer Research , 67 :22 , 2007 |
| Abstract : |
| PubMedSearch : Danks_2007_Cancer.Res_67_22 |
| PubMedID: 17210679 |
| Title : Development of a tumor-selective approach to treat metastatic cancer - Aboody_2006_PLoS.One_1_e23 |
| Author(s) : Aboody KS , Bush RA , Garcia E , Metz MZ , Najbauer J , Justus KA , Phelps DA , Remack JS , Yoon KJ , Gillespie S , Kim SU , Glackin CA , Potter PM , Danks MK |
| Ref : PLoS ONE , 1 :e23 , 2006 |
| Abstract : |
| PubMedSearch : Aboody_2006_PLoS.One_1_e23 |
| PubMedID: 17183650 |
| Title : Development of an etoposide prodrug for dual prodrug-enzyme antitumor therapy - Yoon_2006_Mol.Cancer.Ther_5_1577 |
| Author(s) : Yoon KJ , Qi J , Remack JS , Virga KG , Hatfield MJ , Potter PM , Lee RE , Danks MK |
| Ref : Mol Cancer Ther , 5 :1577 , 2006 |
| Abstract : |
| PubMedSearch : Yoon_2006_Mol.Cancer.Ther_5_1577 |
| PubMedID: 16818517 |
| Title : Identification and characterization of novel benzil (diphenylethane-1,2-dione) analogues as inhibitors of mammalian carboxylesterases - Wadkins_2005_J.Med.Chem_48_2906 |
| Author(s) : Wadkins RM , Hyatt JL , Wei X , Yoon KJ , Wierdl M , Edwards CC , Morton CL , Obenauer JC , Damodaran K , Beroza P , Danks MK , Potter PM |
| Ref : Journal of Medicinal Chemistry , 48 :2906 , 2005 |
| Abstract : |
| PubMedSearch : Wadkins_2005_J.Med.Chem_48_2906 |
| PubMedID: 15828829 |
| Title : Development of prodrugs for enzyme-mediated, tumor-selective therapy - Yoon_2005_Curr.Med.Chem.Anticancer.Agents_5_107 |
| Author(s) : Yoon KJ , Potter PM , Danks MK |
| Ref : Curr Med Chem Anticancer Agents , 5 :107 , 2005 |
| Abstract : |
| PubMedSearch : Yoon_2005_Curr.Med.Chem.Anticancer.Agents_5_107 |
| PubMedID: 15777218 |
| Title : Inhibition of acetylcholinesterase by the anticancer prodrug CPT-11 - Hyatt_2005_Chem.Biol.Interact_157-158_247 |
| Author(s) : Hyatt JL , Tsurkan L , Morton CL , Yoon KJ , Harel M , Brumshtein B , Silman I , Sussman JL , Wadkins RM , Potter PM |
| Ref : Chemico-Biological Interactions , 157-158 :247 , 2005 |
| Abstract : |
| PubMedSearch : Hyatt_2005_Chem.Biol.Interact_157-158_247 |
| PubMedID: 16257398 |
| Title : Inhibition of carboxylesterases by benzil (diphenylethane-1,2-dione) and heterocyclic analogues is dependent upon the aromaticity of the ring and the flexibility of the dione moiety - Hyatt_2005_J.Med.Chem_48_5543 |
| Author(s) : Hyatt JL , Stacy V , Wadkins RM , Yoon KJ , Wierdl M , Edwards CC , Zeller M , Hunter AD , Danks MK , Crundwell G , Potter PM |
| Ref : Journal of Medicinal Chemistry , 48 :5543 , 2005 |
| Abstract : |
| PubMedSearch : Hyatt_2005_J.Med.Chem_48_5543 |
| PubMedID: 16107154 |
| Title : The crystal structure of the complex of the anticancer prodrug 7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothecin (CPT-11) with Torpedo californica acetylcholinesterase provides a molecular explanation for its cholinergic action - Harel_2005_Mol.Pharmacol_67_1874 |
| Author(s) : Harel M , Hyatt JL , Brumshtein B , Morton CL , Yoon KJ , Wadkins RM , Silman I , Sussman JL , Potter PM |
| Ref : Molecular Pharmacology , 67 :1874 , 2005 |
| Abstract : |
| PubMedSearch : Harel_2005_Mol.Pharmacol_67_1874 |
| PubMedID: 15772291 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Characterization of inhibitors of specific carboxylesterases: development of carboxylesterase inhibitors for translational application - Yoon_2004_Mol.Cancer.Ther_3_903 |
| Author(s) : Yoon KJ , Hyatt JL , Morton CL , Lee RE , Potter PM , Danks MK |
| Ref : Mol Cancer Ther , 3 :903 , 2004 |
| Abstract : |
| PubMedSearch : Yoon_2004_Mol.Cancer.Ther_3_903 |
| PubMedID: 15299073 |
| Title : Discovery of novel selective inhibitors of human intestinal carboxylesterase for the amelioration of irinotecan-induced diarrhea: synthesis, quantitative structure-activity relationship analysis, and biological activity - Wadkins_2004_Mol.Pharmacol_65_1336 |
| Author(s) : Wadkins RM , Hyatt JL , Yoon KJ , Morton CL , Lee RE , Damodaran K , Beroza P , Danks MK , Potter PM |
| Ref : Molecular Pharmacology , 65 :1336 , 2004 |
| Abstract : |
| PubMedSearch : Wadkins_2004_Mol.Pharmacol_65_1336 |
| PubMedID: 15155827 |
| Title : Activation of a camptothecin prodrug by specific carboxylesterases as predicted by quantitative structure-activity relationship and molecular docking studies - Yoon_2003_Mol.Cancer.Ther_2_1171 |
| Author(s) : Yoon KJ , Krull EJ , Morton CL , Bornmann WG , Lee RE , Potter PM , Danks MK |
| Ref : Mol Cancer Ther , 2 :1171 , 2003 |
| Abstract : |
| PubMedSearch : Yoon_2003_Mol.Cancer.Ther_2_1171 |
| PubMedID: 14617791 |
| Title : Synthesis and evaluation of esters and carbamates to identify critical functional groups for esterase-specific metabolism - Yoon_2003_Bioorg.Med.Chem_11_3237 |
| Author(s) : Yoon KJ , Morton CL , Potter PM , Danks MK , Lee RE |
| Ref : Bioorganic & Medicinal Chemistry , 11 :3237 , 2003 |
| Abstract : |
| PubMedSearch : Yoon_2003_Bioorg.Med.Chem_11_3237 |
| PubMedID: 12837533 |