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Author Report for: Reetz MT

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    Title: Focused rational iterative site-specific mutagenesis (FRISM)
    Li D, Wu Q, Reetz MT
    Ref: Methods Enzymol, 643:225, 2020 : PubMed

            

    Title: Artificial cysteine-lipases with high activity and altered catalytic mechanism created by laboratory evolution
    Cen Y, Singh W, Arkin M, Moody TS, Huang M, Zhou J, Wu Q, Reetz MT
    Ref: Nat Commun, 10:3198, 2019 : PubMed

            

    Title: Directed Evolution of Artificial Metalloenzymes: A Universal Means to Tune the Selectivity of Transition Metal Catalysts?
    Reetz MT
    Ref: Acc Chem Res, 52:336, 2019 : PubMed

            

    Title: Stereodivergent Protein Engineering of a Lipase To Access All Possible Stereoisomers of Chiral Esters with Two Stereocenters
    Xu J, Cen Y, Singh W, Fan J, Wu L, Lin X, Zhou J, Huang M, Reetz MT, Wu Q
    Ref: Journal of the American Chemical Society, 141:7934, 2019 : PubMed

            

    Title: (1)H, (13)C and (15)N resonance assignments of wild-type Bacillus subtilis Lipase A and its mutant evolved towards thermostability
    Augustyniak W, Wienk H, Boelens R, Reetz MT
    Ref: Biomol NMR Assign, 7:249, 2013 : PubMed

            

    Title: Biophysical characterization of mutants of Bacillus subtilis lipase evolved for thermostability: factors contributing to increased activity retention
    Augustyniak W, Brzezinska AA, Pijning T, Wienk H, Boelens R, Dijkstra BW, Reetz MT
    Ref: Protein Science, 21:487, 2012 : PubMed

            

    Title: Enhancing the efficiency of directed evolution in focused enzyme libraries by the adaptive substituent reordering algorithm
    Feng X, Sanchis J, Reetz MT, Rabitz H
    Ref: Chemistry, 18:5646, 2012 : PubMed

            

    Title: Revisiting the lipase from Pseudomonas aeruginosa: directed evolution of substrate acceptance and enantioselectivity using iterative saturation mutagenesis
    Prasad S, Bocola M, Reetz MT
    Ref: Chemphyschem, 12:1550, 2011 : PubMed

            

    Title: Manipulating the expression rate and enantioselectivity of an epoxide hydrolase by using directed evolution
    Reetz MT, Zheng H
    Ref: Chembiochem, 12:1529, 2011 : PubMed

            

    Title: Increasing the stability of an enzyme toward hostile organic solvents by directed evolution based on iterative saturation mutagenesis using the B-FIT method
    Reetz MT, Soni P, Fernandez L, Gumulya Y, Carballeira JD
    Ref: Chem Commun (Camb), 46:8657, 2010 : PubMed

            

    Title: Manipulating the stereoselectivity of limonene epoxide hydrolase by directed evolution based on iterative saturation mutagenesis
    Zheng H, Reetz MT
    Ref: Journal of the American Chemical Society, 132:15744, 2010 : PubMed

            

    Title: Knowledge-guided laboratory evolution of protein thermolability
    Reetz MT, Soni P, Fernandez L
    Ref: Biotechnol Bioeng, 102:1712, 2009 : PubMed

            

    Title: Directed evolution of an enantioselective epoxide hydrolase: uncovering the source of enantioselectivity at each evolutionary stage
    Reetz MT, Bocola M, Wang LW, Sanchis J, Cronin A, Arand M, Zou J, Archelas A, Bottalla AL and Mowbray SL <1 more author(s)>
    Ref: Journal of the American Chemical Society, 131:7334, 2009 : PubMed

            

    Title: A genetic selection system for evolving enantioselectivity of enzymes
    Reetz MT, Hobenreich H, Soni P, Fernandez L
    Ref: Chem Commun (Camb), :5502, 2008 : PubMed

            

    Title: Improved PCR method for the creation of saturation mutagenesis libraries in directed evolution: application to difficult-to-amplify templates
    Sanchis J, Fernandez L, Carballeira JD, Drone J, Gumulya Y, Hobenreich H, Kahakeaw D, Kille S, Lohmer R and Reetz MT <7 more author(s)>
    Ref: Applied Microbiology & Biotechnology, 81:387, 2008 : PubMed

            

    Title: Learning from directed evolution: Further lessons from theoretical investigations into cooperative mutations in lipase enantioselectivity
    Reetz MT, Puls M, Carballeira JD, Vogel A, Jaeger KE, Eggert T, Thiel W, Bocola M, Otte N
    Ref: Chembiochem, 8:106, 2007 : PubMed

            

    Title: Directed evolution of Bacillus subtilis lipase A by use of enantiomeric phosphonate inhibitors: crystal structures and phage display selection
    Droge MJ, Boersma YL, van Pouderoyen G, Vrenken TE, Ruggeberg CJ, Reetz MT, Dijkstra BW, Quax WJ
    Ref: Chembiochem, 7:149, 2006 : PubMed

            

    Title: Expanding the substrate scope of enzymes: combining mutations obtained by CASTing
    Reetz MT, Carballeira JD, Peyralans J, Hobenreich H, Maichele A, Vogel A
    Ref: Chemistry, 12:6031, 2006 : PubMed

            

    Title: Multiplex-PCR-based recombination as a novel high-fidelity method for directed evolution
    Eggert T, Funke SA, Rao NM, Acharya P, Krumm H, Reetz MT, Jaeger KE
    Ref: Chembiochem, 6:1062, 2005 : PubMed

            

    Title: Learning from directed evolution: theoretical investigations into cooperative mutations in lipase enantioselectivity
    Bocola M, Otte N, Jaeger KE, Reetz MT, Thiel W
    Ref: Chembiochem, 5:214, 2004 : PubMed

            

    Title: Controlling the enantioselectivity of enzymes by directed evolution: practical and theoretical ramifications
    Reetz MT
    Ref: Proc Natl Acad Sci U S A, 101:5716, 2004 : PubMed

            

    Title: Enhancing the enantioselectivity of an epoxide hydrolase by directed evolution
    Reetz MT, Torre C, Eipper A, Lohmer R, Hermes M, Brunner B, Maichele A, Bocola M, Arand M and Furstoss R <3 more author(s)>
    Ref: Org Lett, 6:177, 2004 : PubMed

            

    Title: Liquid poly(ethylene glycol) and supercritical carbon dioxide as a biphasic solvent system for lipase-catalyzed esterification
    Reetz MT, Wiesenhofer W
    Ref: Chem Commun (Camb), :2750, 2004 : PubMed

            

    Title: Binding of phage displayed Bacillus subtilis lipase A to a phosphonate suicide inhibitor
    Droge MJ, Ruggeberg CJ, van der Sloot AM, Schimmel J, Dijkstra DS, Verhaert RM, Reetz MT, Quax WJ
    Ref: J Biotechnol, 101:19, 2003 : PubMed

            

    Title: Lipases as practical biocatalysts
    Reetz MT
    Ref: Curr Opin Chemical Biology, 6:145, 2002 : PubMed

            

    Title: Directed evolution and the creation of enantioselective biocatalysts
    Jaeger KE, Eggert T, Eipper A, Reetz MT
    Ref: Applied Microbiology & Biotechnology, 55:519, 2001 : PubMed

            

    Title: Directed Evolution of an Enantioselective Enzyme through Combinatorial Multiple-Cassette Mutagenesis
    Reetz MT, Wilensek S, Zha D, Jaeger KE
    Ref: Angew Chem Int Ed Engl, 40:3589, 2001 : PubMed

            

    Title: Directed evolution of enantioselective enzymes for organic chemistry
    Jaeger KE, Reetz MT
    Ref: Curr Opin Chemical Biology, 4:68, 2000 : PubMed

            

    Title: Directed evolution of an enantioselective lipase
    Liebeton K, Zonta A, Schimossek K, Nardini M, Lang D, Dijkstra BW, Reetz MT, Jaeger KE
    Ref: Chemical Biology, 7:709, 2000 : PubMed

            

    Title: Enantioselective enzymes for organic synthesis created by directed evolution
    Reetz MT, Jaeger KE
    Ref: Chemistry, 6:407, 2000 : PubMed

            

    Title: Bacterial biocatalysts: molecular biology, three-dimensional structures, and biotechnological applications of lipases
    Jaeger KE, Dijkstra BW, Reetz MT
    Ref: Annu Rev Microbiol, 53:315, 1999 : PubMed

            

    Title: Microbial lipases form versatile tools for biotechnology
    Jaeger KE, Reetz MT
    Ref: Trends Biotechnol, 16:396, 1998 : PubMed

            

    Title: Overexpression, immobilization and biotechnological application of Pseudomonas lipases
    Reetz MT, Jaeger KE
    Ref: Chemistry & Physic of Lipids, 93:3, 1998 : PubMed

            


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