AcoC_BiotinLipoyl-ABH
Relationship
Comment
This family groups proteins with an architecture composed of two or three domains: a Biotin_lipoyl domain, possibly a E3_binding domain and an alpha/beta hydrolase domain. PF00364. Biotin_lipoyl IPR000089. Biotin_lipoyl. Biotin/lipoyl attachment domain has a conserved lysine residue that binds biotin or lipoic acid. Biotin plays a catalytic role in some carboxyl transfer reactions and is covalently attached, via an amide bond, to a lysine residue in enzymes requiring this coenzyme. PF02817. E3_binding. IPR004167. E3-bd. is a small domain of the E2 subunit of 2-oxo-acid dehydrogenases (not an alpha beta hydrolase) that is responsible for the binding of the E3 subunit. Here dihydrolipoamide acetyltransferase (acoC) from the 2,3-butanediol catabolic pathway: acetyl-CoA:enzyme N6-(dihydrolipoyl)lysine S-acetyltransferase. Transfer of thio acetate from Acetyl-CoA to N6-(dihydrolipoyl)lysine of an enzyme
Database
Interpro : No interpro
PIRSF : No PIRSF
Pdoc : No Pdoc
Pfam : PF12697 Abhydrolase_6
Prints : No Print
EC Number : No EC Number
Sequences
| Peptide in | Fasta |
| Nucleotide in | Fasta |
| Alignment with Multalin | Text only |
| Seed alignment with MAFFT | No colour / coloured with Mview |
| Alignment with MAFFT | No colour / coloured with Mview |
| Dendrogram | The dnd file |
| Gene_locus | Name | Species |
|---|---|---|
| 9burk-b5wb88 | Burkholderia sp. H160 Alpha\/beta hydrolase fold | Burkholderia sp. H160 |
| 9rhiz-c4wq75 | Ochrobactrum intermedium LMG 3301 Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex | Ochrobactrum intermedium LMG 3301 |
| 9rhiz-c4wr57 | Ochrobactrum intermedium LMG 3301 Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex | Ochrobactrum intermedium LMG 3301 |
| 9rhob-a3sj80 | Roseovarius nubinhibens ISM Dihydrolipoamide acetyltransferase | Roseovarius nubinhibens ISM |
| 9rhob-a9hdu2 | Roseobacter litoralis Och 149 Branched-chain alpha-keto acid dehydrogenase E2 subunit | Roseobacter litoralis Och 149 |
| 9rhob-b5k4j3 | Octadecabacter antarcticus 238 Dihydrolipoamide acetyltransferase, long form | Octadecabacter antarcticus 238 |
| 9rhob-c8s2q9 | Rhodobacter sp. SW2 Biotin\/lipoyl attachment domain-containing protein | Rhodobacter sp. SW2 |
| acepa-este2 | Acetobacter pasteurianus gene for esterase2 | Acetobacter pasteurianus |
| azoc5-a8i2n5 | Azorhizobium caulinodans (strain ATCC 43989 \/ DSM 5975 \/ ORS 571) Acetoin dehydrogenase complex E2 component protein | Azorhizobium caulinodans |
| azos1-d3nt15 | Azospirillum sp. (strain B510) Pyruvate dehydrogenase E2 component | Azospirillum sp. |
| azovd-c1dex6 | Azotobacter vinelandii (strain DJ \/ ATCC BAA-1303\; AvOP) Dihydrolipoamide acetyltransferase,acetoin dehydrogeanse E2 component, AcoC | Azotobacter vinelandii |
| beii9-b2ibq5 | Beijerinckia indica subsp. indica (strain ATCC 9039 \/ DSM 1715 \/ NCI 8712) Alpha\/beta hydrolase fold | Beijerinckia indica subsp. indica |
| brume-dhE2 | Brucella abortus, Brucella melitensis, Brucella suis, B. canis, B. neotomae, B. sp., B. ceti, B. pinnipedialis, putative dhE2 | Brucella abortus |
| burcc-b1jtb7 | Burkholderia cenocepacia (strain MC0-3) (strain AU 1054) (strain HI2424) (PC 184)alpha\/beta hydrolase fold | Burkholderia cenocepacia |
| burcm-q0beu2 | Burkholderia cepacia, Burkholderia ambifaria, Burkholderia multivorans, Acetoin dehydrogenase E2 component | Burkholderia cepacia |
| burp8-b2jn41 | Burkholderia phymatum (strain DSM 17167 \/ STM815) Alpha\/beta hydrolase fold protein | Burkholderia phymatum |
| burpp-b2tg00 | Burkholderia phytofirmans (strain DSM 17436 \/ PsJN) Alpha\/beta hydrolase fold | Burkholderia phytofirmans |
| burvg-a4jer5 | Burkholderia vietnamiensis, Burkholderi cepacia, Burkholderia dolosa Alpha\/beta hydrolase fold :biotin\/lipoyl attachment | Burkholderia vietnamiensis |
| burxl-q13jv8 | Burkholderia xenovorans (strain LB400) putative acetoin dehydrogenase (EC 2.3.1.12) | Burkholderia xenovorans |
| cuppj-q46pn7 | Cupriavidus pinatubonensis (strain JMP134 \/ LMG 1197) (Alcaligenes eutrophus) (Ralstonia eutropha) alpha\/beta hydrolase fold:biotin\/lipoyl attachment | Ralstonia eutropha |
| cuptr-b2ahw1 | Cupriavidus taiwanensis (strain R1 \/ LMG 19424) (Ralstonia taiwanensis (strain LMG 19424)) Dihydrolipoyllysine-residue acetyltransferase component of acetoin cleaving system | Cupriavidus taiwanensis |
| dinsh-a8lnx4 | Dinoroseobacter shibae (strain DFL 12) Dihydrolipoamide acetyltransferase | Dinoroseobacter shibae |
| gluda-acoc | Gluconacetobacter diazotrophicus (strain ATCC 49037 \/ DSM 5601 PAl5) Putative pyruvate dehydrogenase E2 component Dihydrolipoamide acetyltransferase | Gluconacetobacter diazotrophicus |
| meslo-acoc | Mesorhizobium loti (Rhizobium loti) dihydrolipoamide S-acetyltransferase | Mesorhizobium loti |
| metpp-a2sg73 | Methylibium petroleiphilum (strain PM1) Acetoin dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase | Methylibium petroleiphilum |
| metsb-b8ejc1 | Methylocella silvestris (strain BL2 \/ DSM 15510 \/ NCIMB 13906) Alpha\/beta hydrolase fold protein | Methylocella silvestris |
| nakmy-c8xbn3 | Nakamurella multipartita (strain ATCC 700099 \/ DSM 44233 \/ JCM 9543 \/ Y-104) (Microsphaera multipartita) Alpha\/beta hydrolase fold protein | Nakamurella multipartita |
| ocha4-a6x6g3 | Ochrobactrum anthropi (strain ATCC 49188 \/ DSM 6882 \/ NCTC 12168) Biotin\/lipoyl attachment domain protein | Ochrobactrum anthropi |
| pardp-a1bbz9 | Paracoccus denitrificans (strain Pd 1222) alpha\/beta hydrolase fold | Paracoccus denitrificans |
| pseae-PA4152 | Pseudomonas aeruginosa PA4152 Putative uncharacterized protein | Pseudomonas aeruginosa |
| psef5-q4keq4 | Pseudomonas fluorescens (strain Pf-5 \/ ATCC BAA-477) (EC 2.3.1.12) | Pseudomonas fluorescens |
| psepu-acoc | Pseudomonas putida dihydrolipoamide acetyltransferase (acoC) | Pseudomonas putida |
| cupnh-acoc | Ralstonia eutropha (strain ATCC 17699 \/ H16 \/ DSM 428 \/ Stanier 337 ) (fast-migrating protein) (fmp) dihydrolipoamide acetyltransferase DHLTA | Ralstonia eutropha |
| rhisn-c3klz9 | Rhizobium sp. (strain NGR234) Acoc1 and 2 Dihydrolipoyllysine-residue acetyltransferase component of acetoincleaving system | Rhizobium sp. |
| rubxd-q1ate5 | Rubrobacter xylanophilus (strain DSM 9941 \/ NBRC 16129) alpha\/beta hydrolase fold | Rubrobacter xylanophilus |
| sacen-a4fiz9 | Saccharopolyspora erythraea (strain NRRL 23338) Acetoin dehydrogenase, dihydrolipoamide acetyltransferase component | Saccharopolyspora erythraea |
| silpo-q5llx5 | Silicibacter pomeroyi acetyltransferase (EC 2.3.1.12) | Silicibacter pomeroyi |
| sinmw-a6udy3 | Sinorhizobium medicae (strain WSM419) (Ensifer medicae) Biotin\/lipoyl attachment domain-containing protein | Sinorhizobium medicae |
| sphtd-d1c9y3 | Sphaerobacter thermophilus (strain DSM 20745 \/ S 6022) Alpha\/beta hydrolase fold protein | Sphaerobacter thermophilus |
| verei-a1wk19 | Verminephrobacter eiseniae (strain EF01-2) alpha\/beta hydrolase fold | Verminephrobacter eiseniae |
| xanp2-a7ifm6 | Xanthobacter autotrophicus (strain ATCC BAA-1158 \/ Py2) Biotin\/lipoyl attachment domain-containing protein | Xanthobacter autotrophicus |
| xanp2-a7imm2 | Xanthobacter autotrophicus (strain ATCC BAA-1158 \/ Py2) Alpha\/beta hydrolase fold | Xanthobacter autotrophicus |
References (2)
| Title : Molecular characterization of the Pseudomonas putida 2,3-butanediol catabolic pathway. - Huang_1994_FEMS.Microbiol.Lett_124_141 |
| Author(s) : Huang M , Oppermann FB , Steinbuchel A |
| Ref : FEMS Microbiology Letters , 124 :141 , 1994 |
| Abstract : |
| PubMedSearch : Huang_1994_FEMS.Microbiol.Lett_124_141 |
| PubMedID: 7813883 |
| Gene_locus related to this paper: psepu-acoc |
| Title : Identification and molecular characterization of the Alcaligenes eutrophus H16 aco operon genes involved in acetoin catabolism - Priefert_1991_J.Bacteriol_173_4056 |
| Author(s) : Priefert H , Hein S , Krueger N , Zeh K , Schmidt B , Steinbuechel A |
| Ref : Journal of Bacteriology , 173 :4056 , 1991 |
| Abstract : |
| PubMedSearch : Priefert_1991_J.Bacteriol_173_4056 |
| PubMedID: 2061286 |
| Gene_locus related to this paper: cupnh-acoc |