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Family Report for: PHAZ7_phb_depolymerase

PHAZ7_phb_depolymerase



Relationship
Block X
Comment
Thermoalkalophilic hydrolase of Paucimonas and Shewanella species with high specificity for amorphous polyesters of short chain-length hydroxyalkanoic acids. An unusual substrate specificity for amorphous poly((R)-3-hydroxyalkanoates PHA and no homologies to any other PHB depolymerase. Formerly included in Lipase_2. Family IX was introduced by Handrick et al. (Arpigny_Jaeger Family IX). Paper: Arpigny and Jaeger (1999).

Database
Sequences
Interpro
|
PIRSF
|
Pdoc
|
PFam
|
Prints
|
Prosite
|
no EC number



Peptide in
|Fasta
Nucleotide in
|Fasta
Alignment with Multalin
|Text only/graphic display
Seed alignment with MAFFT
|No colour/coloured with Mview
Alignment with MAFFT
|No colour/coloured with Mview
Dendrogram
|Graphical display, obtained with the dnd file produced by Clustalw

References
1 more
    Title: The structure of PhaZ7 at atomic (1.2 A) resolution reveals details of the active site and suggests a substrate-binding mode
    Wakadkar S, Hermawan S, Jendrossek D, Papageorgiou AC
    Ref: Acta Crystallographica Sect F Struct Biol Cryst Commun, 66:648, 2010 : PubMed

            

    Title: Structural basis of poly(3-hydroxybutyrate) hydrolysis by PhaZ7 depolymerase from Paucimonas lemoignei
    Papageorgiou AC, Hermawan S, Singh CB, Jendrossek D
    Ref: Journal of Molecular Biology, 382:1184, 2008 : PubMed

            

    Title: A new type of thermoalkalophilic hydrolase of Paucimonas lemoignei with high specificity for amorphous polyesters of short chain-length hydroxyalkanoic acids
    Handrick R, Reinhardt S, Focarete ML, Scandola M, Adamus G, Kowalczuk M, Jendrossek D
    Ref: Journal of Biological Chemistry, 276:36215, 2001 : PubMed

            

Other Papers


No structure scheme yet for this family

Structures in PHAZ7_phb_depolymerase family (11)

Genes Proteins in PHAZ7_phb_depolymerase family (34)

Fragments of genes in PHAZ7_phb_depolymerase family (3)

Substrates of some enzymes in the PHAZ7_phb_depolymerase family (3)

No Inhibitor



Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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