armos-armb

Armillaria ostoyae (Armillaria root rot fungus); Armillaria mellea; Armillaria gallica . Non-reducing polyketide synthase ArmB

Comment

Armillaria ostoyae (Armillaria root rot fungus)\; Armillaria mellea (Shoestring root rot fungus) (Honey mushroom)\; Armillaria gallica (Bulbous honey fungus) (Armillaria bulbosa)

Relationship

Family : Thioesterase

Block : X

Position in NCBI Life Tree : Armillaria ostoyae

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Fungi N E > Dikarya N E > Basidiomycota N E > Agaricomycotina N E > Agaricomycetes N E > Agaricomycetidae N E > Agaricales N E > Physalacriaceae N E > Armillaria N E > Armillaria ostoyae N E

Molecular evidence

No mutation

No structure

No kinetic

No disease

No substrate

No inhibitor

Sequence

Peptide

AQVQAGPSSP SSDLVDTKPM FVSVLGLDES DIQDDTEFET IGLDSLTAIE ALHAIQTEYG LELPSNLFEL HTTAKAVNQY ISSKRPGKSP KQVEETAMDP DREEDLSDLT PEQVQSVVRV LRLDEVPMSV QKSSSSGSPL FLFHDGSGAV NYLRRLGSVD REFWGFNNPN YATGKPWGSV EAMASAYADY AVKVAGSRPV IFGGWSFGGV VGFEAARQLM RRGVPVKGVV LIDSPFPVDH VPSSNEFMAV TAGAFTRGGR TPIGRMMWKQ LQQNAPLLKT YDPRIAGGPY PPLVLLHNKE GIPPDAFLPY PVPRWMSEKG TDPCLLADDW SGLVGAPIKV IHLPGTHFTT FATPHLGAVT QALVDGCAYL DGL

References (14)

Title : Susceptibility of Garden Trees and Shrubs to Armillaria Root Rot - Cromey_2020_Plant.Dis_104_483
Author(s) : Cromey MG , Drakulic J , Beal EJ , Waghorn IAG , Perry JN , Clover GRG
Ref : Plant Dis , 104 :483 , 2020
Abstract :
PubMedSearch : Cromey_2020_Plant.Dis_104_483
PubMedID: 31746694
Gene_locus related to this paper: armos-armb

Title : Induction of Autophagic Death of Human Hepatocellular Carcinoma Cells by Armillaridin from Armillaria mellea - Leu_2019_Am.J.Chin.Med_47_1365
Author(s) : Leu YS , Chen YJ , Chen CC , Huang HL
Ref : Am J Chin Med , 47 :1365 , 2019
Abstract :
PubMedSearch : Leu_2019_Am.J.Chin.Med_47_1365
PubMedID: 31488037
Gene_locus related to this paper: armos-armb

Title : Armillaria - Sipos_2018_Curr.Biol_28_R297
Author(s) : Sipos G , Anderson JB , Nagy LG
Ref : Current Biology , 28 :R297 , 2018
Abstract :
PubMedSearch : Sipos_2018_Curr.Biol_28_R297
PubMedID: 29614282
Gene_locus related to this paper: armos-armb

Title : Clonal evolution and genome stability in a 2500-year-old fungal individual - Anderson_2018_Proc.Biol.Sci_285_20182233
Author(s) : Anderson JB , Bruhn JN , Kasimer D , Wang H , Rodrigue N , Smith ML
Ref : Proc Biol Sci , 285 :20182233 , 2018
Abstract :
PubMedSearch : Anderson_2018_Proc.Biol.Sci_285_20182233
PubMedID: 30963893
Gene_locus related to this paper: armos-armb

Title : Genome expansion and lineage-specific genetic innovations in the forest pathogenic fungi Armillaria - Sipos_2017_Nat.Ecol.Evol_1_1931
Author(s) : Sipos G , Prasanna AN , Walter MC , O'Connor E , Balint B , Krizsan K , Kiss B , Hess J , Varga T , Slot J , Riley R , Boka B , Rigling D , Barry K , Lee J , Mihaltcheva S , LaButti K , Lipzen A , Waldron R , Moloney NM , Sperisen C , Kredics L , Vagvolgyi C , Patrignani A , Fitzpatrick D , Nagy I , Doyle S , Anderson JB , Grigoriev IV , Guldener U , Munsterkotter M , Nagy LG
Ref : Nat Ecol Evol , 1 :1931 , 2017
Abstract :
PubMedSearch : Sipos_2017_Nat.Ecol.Evol_1_1931
PubMedID: 29085064
Gene_locus related to this paper: armos-armb

Title : Structure, cytotoxic activity and mechanism of protoilludane sesquiterpene aryl esters from the mycelium of Armillaria mellea - Li_2016_J.Ethnopharmacol_184_119
Author(s) : Li Z , Wang Y , Jiang B , Li W , Zheng L , Yang X , Bao Y , Sun L , Huang Y , Li Y
Ref : J Ethnopharmacol , 184 :119 , 2016
Abstract :
PubMedSearch : Li_2016_J.Ethnopharmacol_184_119
PubMedID: 26952552
Gene_locus related to this paper: armos-armb

Title : Armillaridin induces autophagy-associated cell death in human chronic myelogenous leukemia K562 cells - Chang_2016_Tumour.Biol_37_14291
Author(s) : Chang WH , Huang HL , Huang WP , Chen CC , Chen YJ
Ref : Tumour Biol , 37 :14291 , 2016
Abstract :
PubMedSearch : Chang_2016_Tumour.Biol_37_14291
PubMedID: 27592257
Gene_locus related to this paper: armos-armb

Title : A Fivefold Parallelized Biosynthetic Process Secures Chlorination of Armillaria mellea (Honey Mushroom) Toxins - Wick_2016_Appl.Environ.Microbiol_82_1196
Author(s) : Wick J , Heine D , Lackner G , Misiek M , Tauber J , Jagusch H , Hertweck C , Hoffmeister D
Ref : Applied Environmental Microbiology , 82 :1196 , 2016
Abstract :
PubMedSearch : Wick_2016_Appl.Environ.Microbiol_82_1196
PubMedID: 26655762
Gene_locus related to this paper: armos-armb

Title : Armillaridin, a Honey Medicinal Mushroom, Armillaria mellea (Higher Basidiomycetes) Component, Inhibits Differentiation and Activation of Human Macrophages - Liu_2015_Int.J.Med.Mushrooms_17_161
Author(s) : Liu TP , Chen CC , Shiao PY , Shieh HR , Chen YY , Chen YJ
Ref : Int J Med Mushrooms , 17 :161 , 2015
Abstract :
PubMedSearch : Liu_2015_Int.J.Med.Mushrooms_17_161
PubMedID: 25746621
Gene_locus related to this paper: armos-armb

Title : Therapeutic and radiosensitizing effects of armillaridin on human esophageal cancer cells - Chi_2013_Evid.Based.Complement.Alternat.Med_2013_459271
Author(s) : Chi CW , Chen CC , Chen YJ
Ref : Evid Based Complement Alternat Med , 2013 :459271 , 2013
Abstract :
PubMedSearch : Chi_2013_Evid.Based.Complement.Alternat.Med_2013_459271
PubMedID: 23864890
Gene_locus related to this paper: armos-armb

Title : Assembly of melleolide antibiotics involves a polyketide synthase with cross-coupling activity - Lackner_2013_Chem.Biol_20_1101
Author(s) : Lackner G , Bohnert M , Wick J , Hoffmeister D
Ref : Chemical Biology , 20 :1101 , 2013
Abstract :
PubMedSearch : Lackner_2013_Chem.Biol_20_1101
PubMedID: 23993460
Gene_locus related to this paper: armos-armb

Title : Genome mining reveals the evolutionary origin and biosynthetic potential of basidiomycete polyketide synthases - Lackner_2012_Fungal.Genet.Biol_49_996
Author(s) : Lackner G , Misiek M , Braesel J , Hoffmeister D
Ref : Fungal Genet Biol , 49 :996 , 2012
Abstract :
PubMedSearch : Lackner_2012_Fungal.Genet.Biol_49_996
PubMedID: 23078836
Gene_locus related to this paper: armos-armb

Title : In vitro cytotoxicity of melleolide antibiotics: structural and mechanistic aspects - Bohnert_2011_Bioorg.Med.Chem.Lett_21_2003
Author(s) : Bohnert M , Miethbauer S , Dahse HM , Ziemen J , Nett M , Hoffmeister D
Ref : Bioorganic & Medicinal Chemistry Lett , 21 :2003 , 2011
Abstract :
PubMedSearch : Bohnert_2011_Bioorg.Med.Chem.Lett_21_2003
PubMedID: 21376582
Gene_locus related to this paper: armos-armb

Title : Cloning and characterization of an Armillaria gallica cDNA encoding protoilludene synthase, which catalyzes the first committed step in the synthesis of antimicrobial melleolides - Engels_2011_J.Biol.Chem_286_6871
Author(s) : Engels B , Heinig U , Grothe T , Stadler M , Jennewein S
Ref : Journal of Biological Chemistry , 286 :6871 , 2011
Abstract :
PubMedSearch : Engels_2011_J.Biol.Chem_286_6871
PubMedID: 21148562
Gene_locus related to this paper: armos-armb