tetur-ACHE

Tetranychus urticae (Two-spotted spider mite) tetur19g00850 CCE49 acetylcholinesterase

Comment

There is only one gene of AChE in Tetranychus urticae two-spotted spider mite. The strain TKD is the suceptible strain and the NCN is the resistant strain. AChE gene duplication results in the proportional overexpression which is necessary for the reduced catalytic activity caused by mutations G119S A280T F331W (G228S,A391T,F439W) UD strain is a suceptible strain with GAF G228A391F439, PyriF strain has 50\% G228S mutation in two copies of AChE gene, AD strainshave 6 copies of AChE with mutation frequencies of 50\% for G228S and 75\% F439W. Other strains: Tetranychus kanzawai Kanzawa spider mite (only three aa different between ACHE in the two species Aiki et al. They show F439W mutation in resistant strain

Relationship

Family : ACHE

Block : C

Position in NCBI Life Tree : Tetranychus urticae

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Protostomia N E > Ecdysozoa N E > Panarthropoda N E > Arthropoda N E > Chelicerata N E > Arachnida N E > Acari N E > Acariformes N E > Trombidiformes N E > Prostigmata N E > Eleutherengona N E > Raphignathae N E > Tetranychoidea N E > Tetranychidae N E > Tetranychus N E > Tetranychus urticae N E

Molecular evidence

No mutation

No structure

No kinetic

No disease

No substrate

No inhibitor

Database

Sequence

Peptide

MVPMFNHNIN HFNNVIVTTL THHQYTNSRC NSNNNVIKRI TNSILKSVTV FTVKTLWNHL LVPIVVILLF QSSANVFSSA LPHSEINSFH ADGPSSSSSF NSEHHHHHHH NDPLVVLTKK GYVRGRSVVS PTGKPVDAFL GIRYAKPPTG KFRFRHPKPI DSWQGIFNAT SFSGACYQVN DTFFGNFMGA TEWNPNVPLD EDCLSVNIWV PRPRPKSAAV LLWIYGGGFW SGSSSLDFYD GSVLAGEESI IFVSINYRVA SLGFIFFDTS DAPGNAGLFD QLMAMEWIRE NIAAFGGNPA NITIFGESAG AVSAALHLLS PLSRNVFSQA ILQSGSATCP WAISDRKKAY QRSLALAQAV GCGSTSTRSV HAIIECMQSI PASELVAQEE TTTGVVEFAF IPIVDGSFLD EDPEVSLRTK NFKHTPILTG SNRDEGTYFL VYHSPHIFNL SEGIYISRSE FQSLIRIIYP HLSPLAQEAV IQEYTHWINP DDQIENREAT DKFVGDYHFT CPVNEMSYRY ALYGNDVWTY HFTHRSSKSF WPSWMGVIHG EEIKFVLGEP LDPVHGYTPA EVQLSKRIMR YWANFARTGN PNKQFPDGDD TESIVWPEYT AHEKEYLVIS TNDSSIGRGL RAKQCAFWKN FLPKLINALE NRHNSTCTSH SNQIGSSNWS LAISLISLIM CFLPSLR

References (10)

Title : Identification and characterization of striking multiple-insecticide resistance in a Tetranychus urticae field population from Greece - Papapostolou_2021_Pest.Manag.Sci_77_666
Author(s) : Papapostolou KM , Riga M , Charamis J , Skoufa E , Souchlas V , Ilias A , Dermauw W , Ioannidis P , Van Leeuwen T , Vontas J
Ref : Pest Manag Sci , 77 :666 , 2021
PubMedID: 33051974
Gene_locus related to this paper: tetur-ACHE

Title : Acaricide resistance status and identification of resistance mutations in populations of the two-spotted spider mite Tetranychus urticae from Ethiopia - Simma_2020_Exp.Appl.Acarol_82_475
Author(s) : Simma EA , Hailu B , Jonckheere W , Rogiers C , Duchateau L , Dermauw W , Van Leeuwen T
Ref : Exp Appl Acarol , 82 :475 , 2020
PubMedID: 33174613
Gene_locus related to this paper: tetur-ACHE

Title : Global distribution and origin of target site insecticide resistance mutations in Tetranychus urticae - Ilias_2014_Insect.Biochem.Mol.Biol_48_17
Author(s) : Ilias A , Vontas J , Tsagkarakou A
Ref : Insect Biochemistry & Molecular Biology , 48 :17 , 2014
PubMedID: 24602758
Gene_locus related to this paper: tetur-ACHE

Title : The overexpression of acetylcholinesterase compensates for the reduced catalytic activity caused by resistance-conferring mutations in Tetranychus urticae - Kwon_2012_Insect.Biochem.Mol.Biol_42_212
Author(s) : Kwon DH , Choi JY , Je YH , Lee SH
Ref : Insect Biochemistry & Molecular Biology , 42 :212 , 2012
PubMedID: 22198354
Gene_locus related to this paper: tetur-ACHE

Title : Acetylcholinesterase point mutations putatively associated with monocrotophos resistance in the two-spotted spider mite - Kwon_2010_Pestic.Biochem.Physiol_96_36
Author(s) : Kwon DH , Im JS , Ahn JJ , Lee J-H , Clark JM , Lee SH
Ref : Pesticide Biochemistry and Physiology , 96 :36 , 2010
PubMedID:
Gene_locus related to this paper: tetur-ACHE

Title : Acetylcholinesterase point mutations in European strains of Tetranychus urticae (Acari: Tetranychidae) resistant to organophosphates - Khajehali_2010_Pest.Manag.Sci_66_220
Author(s) : Khajehali J , Van Leeuwen T , Grispou M , Morou E , Alout H , Weill M , Tirry L , Vontas J , Tsagkarakou A
Ref : Pest Manag Sci , 66 :220 , 2010
PubMedID: 19894225
Gene_locus related to this paper: tetur-ACHE

Title : Extensive gene duplication of acetylcholinesterase associated with organophosphate resistance in the two-spotted spider mite - Kwon_2010_Insect.Mol.Biol_19_195
Author(s) : Kwon DH , Clark JM , Lee SH
Ref : Insect Molecular Biology , 19 :195 , 2010
PubMedID: 20002213
Gene_locus related to this paper: tetur-ACHE

Title : Amino acid substitution in Ace paralogous acetylcholinesterase accompanied by organophosphate resistance in the spider mite Tetranychus kanzawai - Aiki_2005_Pestic.Biochem.Physiol_82_154
Author(s) : Aiki Y , Kozaki T , Mizuno H , Kono Y
Ref : Pesticide Biochemistry and Physiology , 82 :154 , 2005
PubMedID:
Gene_locus related to this paper: tetur-ACHE

Title : Sequence of a cDNA encoding acetylcholinesterase from susceptible and resistant two-spotted spider mite, Tetranychus urticae - Anazawa_2003_Insect.Biochem.Mol.Biol_33_509
Author(s) : Anazawa Y , Tomita T , Aiki Y , Kozaki T , Kono Y
Ref : Insect Biochemistry & Molecular Biology , 33 :509 , 2003
PubMedID: 12706630
Gene_locus related to this paper: tetur-ACHE