mouse-4neur

Mus musculus (Mouse) neuroligin 4

Comment

Relationship

Family : Neuroligin

Block : C

Position in NCBI Life Tree : Mus musculus

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Deuterostomia N E > Chordata N E > Craniata N E > Vertebrata N E > Gnathostomata N E > Teleostomi N E > Euteleostomi N E > Sarcopterygii N E > Dipnotetrapodomorpha N E > Tetrapoda N E > Amniota N E > Mammalia N E > Theria N E > Eutheria N E > Boreoeutheria N E > Euarchontoglires N E > Glires N E > Rodentia N E > Myomorpha N E > Muroidea N E > Muridae N E > Murinae N E > Mus [genus] N E > Mus [subgenus] N E > Mus musculus N E

Molecular evidence

No mutation

No structure

No kinetic

No disease

No substrate

No inhibitor

Database

Sequence

Peptide

MPAPAPALLC LALALASAQP SPPPPPPFPV VATNYGKLRG VRAALPGDVL GPVTQFLGVP YAAPPTGERR FQPPEPPSSW AGVRDATRFA PVCPQHLDER ALLRDRLPAW FAANLDAIAA YVQDQSEDCL YLNLYVPGGA NGKKMADDVT GNDHGDDQDS RDPGVGGAAA AAARKPVMVY IHGGSYMEGT ANIVDGSVLA SYGDVIVVTV NYRLGVLGFL STGDQAAKGN YGLLDQIQAL RWVEENAGAF GGDPDRVTVF GSGAGASCVS LLTLSHYSEG LFQKAIIQSG TALSSWAVNY QPARYARALG ERVGCATPDP GSPPGSPPGW DSASLVSCLR GKAAGELARA RVTPATYHVA FGPTVDGDVI PDDPQILMEQ GEFLNYDIML GVNQGEGARF VDGLGGGHDG GYGGYGGGYG GGVEDDEVQD GGPDGAAGGV SAGEFDLAVS GFINDLYGRP EGRGDALRET VKFMYTDWAD RDSPEARRKT LVALFTDHQW VAPAVATADL HARYGSPTYF YAFYHRCHGG GGGGGGVDGV AGGVAGGVGG EEARPAWADA AHGDEVPYVF GVPMAGPGDV FGCNFSRNDV MLSAVVMTYW TNFAKTGDPN QPVAQDTRFV HTRPNRFEEV AWAKYDPRGQ LYLHIGLRPR VRDHYRAAKV AFWLELVPHL HGLAADPGAY LSAAATRAAP SGDPDRDPGG GGGGRRRPRP ATRRPAVMTS SSMASGSGMT SSSGSGMTSS SGSSASAVLI ETRRDYSTEL SVTIAVGASL LFLNVLAFAA LYYKKDKRRH ETHRRPPPPR PPQAPPSAAA ADRNPRPDPG PAGRRGGECG AVVTAMAAEA SAGGLGHDGV GGVGVGGVIG GVAGLRLACP PDYALTLRRS PDDVPRAGAG PGAMTLIPGA LGGGGGGAVH GFNTFGSGVG VAGVAGVATS QAGPGLPHGH STTRV

References (7)

Title : Sex-Specific Microglia State in the Neuroligin-4 Knock-Out Mouse Model of Autism Spectrum Disorder - Guneykaya_2023_Brain.Behav.Immun__
Author(s) : Guneykaya D , Ugursu B , Logiacco F , Popp O , Almut Feiks M , Meyer N , Wendt S , Semtner M , Cherif F , Gauthier C , Madore C , Yin Z , Cinar O , Arslan T , Gerevich Z , Mertins P , Butovsky O , Kettenmann H , Wolf SA
Ref : Brain Behavior & Immunity , : , 2023
PubMedID: 37001827
Gene_locus related to this paper: mouse-4neur

Title : NLGN4X TCR transgenic T cells to treat gliomas - Kramer_2023_Neuro.Oncol__
Author(s) : Kramer C , Kilian M , Chih YC , Kourtesakis A , Hoffmann DC , Boschert T , Koopmann P , Sanghvi K , De Roia A , Jung S , Jahne K , Day B , Shultz LD , Ratliff M , Harbottle R , Green EW , Will R , Wick W , Platten M , Bunse L
Ref : Neuro Oncol , : , 2023
PubMedID: 37715782
Gene_locus related to this paper: human-NLGN4X , mouse-4neur

Title : Evolution of the Autism-Associated Neuroligin-4 Gene Reveals Broad Erosion of Pseudoautosomal Regions in Rodents - Maxeiner_2020_Mol.Biol.Evol__
Author(s) : Maxeiner S , Benseler F , Krasteva-Christ G , Brose N , Sudhof TC
Ref : Molecular Biology Evolution , : , 2020
PubMedID: 32011705
Gene_locus related to this paper: mouse-4neur

Title : Autism-associated neuroligin-4 mutation selectively impairs glycinergic synaptic transmission in mouse brainstem synapses - Zhang_2018_J.Exp.Med_215_1543
Author(s) : Zhang B , Gokce O , Hale WD , Brose N , Sudhof TC
Ref : J Exp Med , 215 :1543 , 2018
PubMedID: 29724786
Gene_locus related to this paper: mouse-4neur

Title : Unusually rapid evolution of Neuroligin-4 in mice - Bolliger_2008_Proc.Natl.Acad.Sci.U.S.A_105_6421
Author(s) : Bolliger MF , Pei J , Maxeiner S , Boucard AA , Grishin NV , Sudhof TC
Ref : Proc Natl Acad Sci U S A , 105 :6421 , 2008
PubMedID: 18434543
Gene_locus related to this paper: mouse-4neur

Title : Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism - Jamain_2008_Proc.Natl.Acad.Sci.U.S.A_105_1710
Author(s) : Jamain S , Radyushkin K , Hammerschmidt K , Granon S , Boretius S , Varoqueaux F , Ramanantsoa N , Gallego J , Ronnenberg A , Winter D , Frahm J , Fischer J , Bourgeron T , Ehrenreich H , Brose N
Ref : Proc Natl Acad Sci U S A , 105 :1710 , 2008
PubMedID: 18227507
Gene_locus related to this paper: mouse-4neur

Title : Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism - Jamain_2003_Nat.Genet_34_27
Author(s) : Jamain S , Quach H , Betancur C , Rastam M , Colineaux C , Gillberg IC , Soderstrom H , Giros B , Leboyer M , Gillberg C , Bourgeron T
Ref : Nat Genet , 34 :27 , 2003
PubMedID: 12669065
Gene_locus related to this paper: human-NLGN2 , human-NLGN4X , human-NLGN4Y , mouse-4neur , human-NLGN3