pig-a9gyw6

Sus scrofa (Pig) APLE Alternative Pig Liver Esterase

Comment

There are at least 6 isoenzyme (may be different genes Q9TS80 PLE1 A5A4F5 PLE3). Isoenzymes of pig-liver esterase reveal striking differences in enantioselectivities Hummel et al. 2007<\/A>. Polyisoprenylated. methylated protein methyl esterase (PMPMEase). Pig liver esterase 5 (PLE5) (pig-a9gyw6<\/A>) is the isoenzyme crystallized (5FV4<\/A>)

Relationship

Family : Carb_B_Chordata

Block : C

Position in NCBI Life Tree : Sus scrofa

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Deuterostomia N E > Chordata N E > Craniata N E > Vertebrata N E > Gnathostomata N E > Teleostomi N E > Euteleostomi N E > Sarcopterygii N E > Dipnotetrapodomorpha N E > Tetrapoda N E > Amniota N E > Mammalia N E > Theria N E > Eutheria N E > Boreoeutheria N E > Laurasiatheria N E > Cetartiodactyla N E > Suina N E > Suidae N E > Sus N E > Sus scrofa N E

Molecular evidence

No mutation

No kinetic

No disease

No substrate

No inhibitor

Database

Sequence

Peptide

GQPASPPVVD TAQGRVLGKY VSLEGLAQPV AVFLGVPFAK PPLGSLRFAP PQPAEPWSFV KNTTSYPPMC CQEPIGGQML SDLFTNRKER LIPEFSEDCL YLNIYTPADL TKRGRLPVMV WIHGGGLVVG GASTYDGLAL AAHENVVVVA IQYRLGIWGF FSTGDEHSRG NWGHLDQVAA LHWVQENIAN FGGDPGSVTI FGESAGGESV SVLVLSPLAK NLFHRAISES GVAFTAGLVR KDMKAAAKQI AVLAGCKTTT SAVFVHCLRQ KSEDELLDLT LKMKFFALDL HGDPRESHPF LTTVVDGVLL PKMPEEILAE KDFNTVPYIV GINKQEFGWL LPTMMGFPLS EGKLDQKTAT SLLWKSYPIA NIPEELTPVA TDKYLGGTDD PVKKKDLFLD LMGDVVFGVP SVTVARQHRD AGAPTYMYEF QYRPSFSSDK KPKTVIGDHG DEIFSVFGFP LLKGDAPEEE VSLSKTVMKF WANFARSGNP NGEGLPHWPM YDQEEGYLQI GVNTQAAKRL KGEEVAFWND LLSKEAAKKP PKIKHAEL

References (3)

Title : Regioselective ester cleavage of di-(2-ethylhexyl) trimellitates by porcine liver esterase - Hollerer_2018_Toxicol.In.Vitro_47_178
Author(s) : Hollerer C , Becker G , Goen T , Eckert E
Ref : Toxicol In Vitro , 47 :178 , 2018
PubMedID: 29180039
Gene_locus related to this paper: pig-a9gyw6 , pig-EST1 , pig-a0a1s6l948 , pig-a0a1s6l967

Title : Breed Differences in Pig Liver Esterase (PLE) between Tongcheng (Chinese Local Breed) and Large White Pigs - Xiao_2018_Sci.Rep_8_16364
Author(s) : Xiao Q , Zhou Q , Yang L , Tian Z , Wang X , Xiao Y , Shi D
Ref : Sci Rep , 8 :16364 , 2018
PubMedID: 30397234
Gene_locus related to this paper: pig-a9gyw6 , pig-EST1 , pig-PLE1 , pig-a0a1s6l948 , pig-a0a1s6l959 , pig-a0a1s6l967

Title : Alternative pig liver esterase (APLE) - cloning, identification and functional expression in Pichia pastoris of a versatile new biocatalyst - Hermann_2008_J.Biotechnol_133_301
Author(s) : Hermann M , Kietzmann MU , Ivancic M , Zenzmaier C , Luiten RG , Skranc W , Wubbolts M , Winkler M , Birner-Gruenberger R , Pichler H , Schwab H
Ref : J Biotechnol , 133 :301 , 2008
PubMedID: 18078679
Gene_locus related to this paper: pig-a9gyw6