plaf7-q8ii19

Plasmodium falciparum (isolate 3D7) PF3D7_1134500 GPI inositol-deacylase

Comment

only c-term PGAP1 1523-1738

Relationship

Family : PGAP1

Block : X

Position in NCBI Life Tree : Plasmodium falciparum

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Eukaryota N E > Alveolata N E > Apicomplexa N E > Aconoidasida N E > Haemosporida N E > Plasmodiidae N E > Plasmodium N E > Plasmodium (Laverania) N E > Plasmodium falciparum N E

Molecular evidence

No mutation

No structure

No kinetic

No disease

No substrate

Database

Sequence

Peptide

MYNYYMNVVN SFFNTKKDDN NNNNNILEYN AHKEKYFYTD RMNFDEMSSF LLKKLKNTNI GKKNDIMFVA HSMGGLLTQY ILLKNDHFLN KTKCIFFYAT PHFGSPLSSS AYLLKPFLSP YVYQLNDYDS KLNYLQQSFK ERIKNKDLVI YSFSESEKSP LPFIGVYTMI VPCTSAYLYY SKIFTIIKYC NHLEISKLNS EEDVKFYYLN KVMKEFSKIK

References (1)

Title : The Antimalarial Natural Product Salinipostin A Identifies Essential alpha\/beta Serine Hydrolases Involved in Lipid Metabolism in P. falciparum Parasites - Yoo_2020_Cell.Chem.Biol_27_143
Author(s) : Yoo E , Schulze CJ , Stokes BH , Onguka O , Yeo T , Mok S , Gnadig NF , Zhou Y , Kurita K , Foe IT , Terrell SM , Boucher MJ , Cieplak P , Kumpornsin K , Lee MCS , Linington RG , Long JZ , Uhlemann AC , Weerapana E , Fidock DA , Bogyo M
Ref : Cell Chemical Biology , 27 :143 , 2020
PubMedID: 31978322
Gene_locus related to this paper: plaf7-q8ii19 , plafa-a0a143zya4 , plaf7-q8iik5 , plafa-MAL8P1.38 , plafa-PF07.0040 , plafa-PF10.0020 , plafa-PF10.0379 , plafa-PF13.0153