Saccharomyces cerevisiae (Baker's yeast) (strains YJM789; RM11-1a; AWRI1631) Uncharacterized membrane protein Mil1 YFL034W
The lipase like protein: yeast-yfd4 Mil1(Yfl034w), specifically binds Apm2, one of the adaptor protein of (AP) complexes responsible for binding clathrin, cargo-sorting motifs, accessory factors, and membrane lipids. The paper by Whitfield et al.<\/A> is the first description of a function for a member of the Duf_726<\/A> family. The same protein had been shown to interact with the ribosomal phosphoprotein P0 Aruna et al.<\/A>.. yeast-yfd4 has a conserved catalytic triad || only central part Pfam A DUF726 536 875
Family : Duf_726
Block : X
Position in NCBI Life Tree : Saccharomyces cerevisiae
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Fungi N E > Dikarya N E > Ascomycota N E > saccharomyceta N E > Saccharomycotina N E > Saccharomycetes N E > Saccharomycetales N E > Saccharomycetaceae N E > Saccharomyces N E > Saccharomyces cerevisiae N EMVGGSLVLGL SGGLLAPVIG GGIAAGLSTI GITGATSFLT GVGGTTVVAV SSTAIGANIG ARGMSKRMGS VRTFEFRPLH NNRRVNLILT VSGWMVGNED DVRLPFSTVD PVEGDLYSLY WEPEMLKSIG QTVSIVATEI FTTSLQQILG ATVLTALISS IQWPMALSKL GYILDNPWNV SLDRAWSAGK ILADTLIARN LGARPITLVG FSIGARVIFS CLIELCKKKA LGLIENVYLF GTPAVMKKEQ LVMARSVVSG RFVNGYSDKD WFLAYLFRAA AGGFSAVMGI STIENVEGIE NINCTEFVDG HLNYRKSMPK LLKRIGIAV
| Title : The alternate AP-1 adaptor subunit Apm2 interacts with the Mil1 regulatory protein and confers differential cargo sorting - Whitfield_2016_Mol.Biol.Cell_27_588 |
| Author(s) : Whitfield ST , Burston HE , Bean BD , Raghuram N , Maldonado-Baez L , Davey M , Wendland B , Conibear E |
| Ref : Mol Biology of the cell , 27 :588 , 2016 |
| Abstract : |
| PubMedSearch : Whitfield_2016_Mol.Biol.Cell_27_588 |
| PubMedID: 26658609 |
| Gene_locus related to this paper: yeast-yfd4 |
| Title : Comparative genome analysis of a Saccharomyces cerevisiae wine strain - Borneman_2008_FEMS.Yeast.Res_8_1185 |
| Author(s) : Borneman AR , Forgan AH , Pretorius IS , Chambers PJ |
| Ref : FEMS Yeast Res , 8 :1185 , 2008 |
| Abstract : |
| PubMedSearch : Borneman_2008_FEMS.Yeast.Res_8_1185 |
| PubMedID: 18778279 |
| Gene_locus related to this paper: yeast-AIM2 , yeast-BST1 , yeast-cbpy1 , yeast-cld1 , yeast-dap1 , yeast-dap2 , yeast-dlhh , yeast-ECM18 , yeast-FSH1 , yeast-FSH3 , yeast-ict1 , yeast-kex01 , yeast-LDH1 , yeast-MCFS1 , yeast-MCFS2 , yeast-met2 , yeast-mgll , yeast-pdat , yeast-ppme1 , yeast-ROG1 , yeast-SAY1 , yeast-tgl1 , yeast-tgl2 , yeast-yby9 , yeast-YDR428C , yeast-YDR444W , yeast-yfd4 , yeast-yg19 , yeast-yj68 , yeast-yj77 , yeast-yjg8 , yeast-YLL012W , yeast-YLR020C , yeast-YLR118c , yeast-ym60 , yeast-ynl5 , yeast-yo059 , yeast-YPR147C , yeast-hda1 |
| Title : A multidimensional chromatography technology for in-depth phosphoproteome analysis - Albuquerque_2008_Mol.Cell.Proteomics_7_1389 |
| Author(s) : Albuquerque CP , Smolka MB , Payne SH , Bafna V , Eng J , Zhou H |
| Ref : Mol Cell Proteomics , 7 :1389 , 2008 |
| Abstract : |
| PubMedSearch : Albuquerque_2008_Mol.Cell.Proteomics_7_1389 |
| PubMedID: 18407956 |
| Gene_locus related to this paper: yeast-YDR428C , yeast-YDR444W , yeast-yfd4 |
| Title : A global topology map of the Saccharomyces cerevisiae membrane proteome - Kim_2006_Proc.Natl.Acad.Sci.U.S.A_103_11142 |
| Author(s) : Kim H , Melen K , Osterberg M , von Heijne G |
| Ref : Proc Natl Acad Sci U S A , 103 :11142 , 2006 |
| Abstract : |
| PubMedSearch : Kim_2006_Proc.Natl.Acad.Sci.U.S.A_103_11142 |
| PubMedID: 16847258 |
| Gene_locus related to this paper: yeast-yfd4 |
| Title : Synergistic computational and experimental proteomics approaches for more accurate detection of active serine hydrolases in yeast - Baxter_2004_Mol.Cell.Proteomics_3_209 |
| Author(s) : Baxter SM , Rosenblum JS , Knutson S , Nelson MR , Montimurro JS , Di Gennaro JA , Speir JA , Burbaum JJ , Fetrow JS |
| Ref : Mol Cell Proteomics , 3 :209 , 2004 |
| Abstract : |
| PubMedSearch : Baxter_2004_Mol.Cell.Proteomics_3_209 |
| PubMedID: 14645503 |
| Gene_locus related to this paper: yeast-FSH1 , yeast-FSH2 , yeast-FSH3 , yeast-mgll , yeast-ppme1 , yeast-YDR428C , yeast-yfd4 , yeast-YLR118c |
| Title : Identification of a hypothetical membrane protein interactor of ribosomal phosphoprotein P0 - Aruna_2004_J.Biosci_29_33 |
| Author(s) : Aruna K , Chakraborty T , Nambeesan S , Mannan AB , Sehgal A , Bhalchandara SR , Sharma S |
| Ref : J Biosci , 29 :33 , 2004 |
| Abstract : |
| PubMedSearch : Aruna_2004_J.Biosci_29_33 |
| PubMedID: 15286401 |
| Gene_locus related to this paper: yeast-yfd4 |
| Title : Global analysis of protein expression in yeast - Ghaemmaghami_2003_Nature_425_737 |
| Author(s) : Ghaemmaghami S , Huh WK , Bower K , Howson RW , Belle A , Dephoure N , O'Shea EK , Weissman JS |
| Ref : Nature , 425 :737 , 2003 |
| Abstract : |
| PubMedSearch : Ghaemmaghami_2003_Nature_425_737 |
| PubMedID: 14562106 |
| Gene_locus related to this paper: yeast-AIM2 , yeast-ECM18 , yeast-FSH1 , yeast-FSH2 , yeast-MCFS1 , yeast-MCFS2 , yeast-mgll , yeast-YDL109C , yeast-YDR444W , yeast-yfd4 , yeast-yjg8 , yeast-YLR118c , yeast-yo059 , yeast-YPR147C , yeast-hda1 , yeast-ymc0 |
| Title : Analysis of the nucleotide sequence of chromosome VI from Saccharomyces cerevisiae - Murakami_1995_Nat.Genet_10_261 |
| Author(s) : Murakami Y , Naitou M , Hagiwara H , Shibata T , Ozawa M , Sasanuma S , Sasanuma M , Tsuchiya Y , Soeda E , Yokoyama K , et al. |
| Ref : Nat Genet , 10 :261 , 1995 |
| Abstract : |
| PubMedSearch : Murakami_1995_Nat.Genet_10_261 |
| PubMedID: 7670463 |
| Gene_locus related to this paper: yeast-BST1 , yeast-yfd4 |