Gene_locus Report for: canal-q59ln6 Candida albicans SC5314 hypothetical protein
Comment
Other strains: Candida albicans P78048 L26 19F SC5314 P87 P94015 P57072 P37039 SC5314 GC75 P75010 P57055 WO-1 Relationship
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.) cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Fungi: N E > Dikarya: N E > Ascomycota: N E > saccharomyceta: N E > Saccharomycotina: N E > Saccharomycetes: N E > Saccharomycetales: N E > Debaryomycetaceae: N E > Candida/Lodderomyces clade: N E > Candida [Debaryomycetaceae]: N E > Candida albicans: N E > Candida albicans SC5314: N E 6_AlphaBeta_hydrolase :
canal-q5ams7 Candida albicans SC5314 hypothetical protein ,
canal-q59k70 Candida albicans SC5314 hypothetical protein ,
canal-q59s22 Candida albicans SC5314 potential vacuolar protein ,
canal-q59vf1 Candida albicans SC5314 potential esterase/lipase/thioesterase/phosphatase .
A85-EsteraseD-FGH :
canal-q59nl9 Candida albicans SC5314 hypothetical protein .
ABHD11-Acetyl_transferase :
canal-q5a0i7 Candida albicans SC5314 hypothetical protein ,
canal-q59we9 Candida albicans SC5314 hypothetical protein .
ABHD13-BEM46 :
canal-q5acl5 Candida albicans SC5314 hypothetical protein .
abh_upf0017 :
canal-q59u61 Candida albicans (strains WO-1; SC5314) (Yeast) hypothetical protein .
Acidic_Lipase :
canal-q5ad17 Candida albicans, Candida tropicalis, Candida dubliniensis (Yeast) hypothetical protein tgl1 ,
canal-q5akz5 Candida albicans, Candida dubliniensis (Yeast) hypothetical protein tgl99 .
Carboxypeptidase_S10 :
canal-q5aa97 Candida albicans PRC3 CPY2 potential serine carboxypeptidase ,
canal-q59nw6 Candida albicans (Yeast), Candida dubliniensis, potential serine carboxypeptidase .
CGI-58_ABHD5_ABHD4 :
canal-q59ng0 Candida albicans SC5314 cardiolipin-specific phospholipase ,
canal-q59y42 Candida albicans SC5314 hypothetical protein ,
canal-q59y97 Candida albicans (strains SC5314; WO-1) (Yeast)hypothetical protein .
Dienelactone_hydrolase :
canal-q5ai87 Candida albicans SC5314 hypothetical protein ,
canal-q5amn4 Candida albicans SC5314 hypothetical protein ,
canal-q5amn7 Candida albicans SC5314 hypothetical protein .
DPP4N_Peptidase_S9 :
canal-q5ag57 Candida albicans, Candida dubliniensis, hypothetical protein dap2 ,
canal-q59m48 Candida albicans, Candida dubliniensis, potential alpha-factor pheromone maturation protease .
Duf_676 :
canal-q5ak29 Candida albicans SC5314 hypothetical protein ,
canal-q5ams2 Candida albicans SC5314 hypothetical protein ,
canal-q59kl3 Candida albicans potential lipid particle serine esterase .
FSH1 :
canal-q5adx4 Candida albicans; Candida dubliniensis hypothetical protein ,
canal-q5akr2 Candida albicans; Candida dubliniensis hypothetical protein .
Fusarinine_C_esterase_sidJ :
canal-q5ajt3 Candida albicans (Yeast). hypothetical protein .
Homoserine_transacetylase :
canal-q5a948 Candida albicans SC5314 potential homoserine o-trans-acetylase ,
canal-q59tt5 Candida albicans SC5314 potential serine o-trans-acetylase .
Lipase_3 :
canal-q5amg8 Candida albicans SC5314 potential triglyceride lipase ,
canal-q59xq6 Candida albicans SC5314 potential secreted triacylglycerol lipase. Autophagy-related protein 15 .
LYsophospholipase_carboxylesterase :
canal-apth1 Candida albicans SC5314 likely phospholipase/carboxylesterase .
Monoglyceridelipase_lysophospholip :
canal-q5apu4 Candida albicans, Candida dubliniensis hypothetical protein yju3 .
Palmitoyl-protein_thioesterase :
canal-q5a6l4 Candida albicans SC5314 hypothetical protein ppt2 .
PC-sterol_acyltransferase :
canal-q5abf2 Candida albicans SC5314 hypothetical protein lro1 .
PGAP1 :
canal-q5ai09 Candida albicans (strains SC5314; WO-1) hypothetical protein tgl2 ,
canal-q59vp0 Candida albicans (strains SC5314; WO-1) hypothetical protein bst1 .
PPase_methylesterase_euk :
canal-ppme1 Candida albicans (and strain WO-1)Candida dubliniensis (strain CD36 / CBS 7987 / NCPF 3949 / NRR Y-17841) protein phosphatase methylesterase 1 (EC 3.1.1.-) (pme-1) .
Proline_iminopeptidase :
canal-q5a2i9 Candida albicans (Yeast) hypothetical protein pna1 Warning: This entry is a compilation of different species or line or strain with more than 90% amino acide identity. You can
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(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.) Candida albicans WO-1:
N ,
E .
Molecular evidence
Database
No mutation No structure No kinetic No Substrate No inhibitor
> 3 Genbank links12 more : AACQ01000251 , KGR12483 , KGU13747 < 15 Genbank links12 less : AACQ01000251 , KGR12483 , KGU13747 , KGU12033 , KHC80037 , KHC87564 , KGU09958 , KGQ87724 , KGR10594 , KHC56482 , XP_710647 , KGQ99407 , KHC64493 , KGU33249 , EEQ44164 2 UniProt :
A0A1D8PJ34 ,
C4YPM5 2 Interpro :
A0A1D8PJ34 ,
C4YPM5 2 Pfam :
A0A1D8PJ34 ,
C4YPM5 2 PIRSF :
A0A1D8PJ34 ,
C4YPM5 2 SUPERFAM :
A0A1D8PJ34 ,
C4YPM5
Sequence
Graphical view for this peptide sequence: canal-q59ln6 Colored MSA for Duf_676 (raw)
MAAHPSLWYRDKDSLRIGGVARYTIEYTRLDPTIKRIYFRLKNIEKSSIR
AIHLLSGPFILYCHVVPCNYNPRKPFHPENVQKNTEVVFENQIKPNQAFN
VSLLLNSNSLKGKDDKGYDIFQWEIEIVSQIVITKKTEVVYDFMIGDDLH
FMKKLGQSIIQQTLTSLGTKIDMNEGTKPTIVDKAMDEIHNDSHKIYNTQ
LKVSKLTTDDIWSNEPKDPKKPVHLVIVTHGIFSNLTADMLYIKDQLELR
VKENILVRGYRYNAGRTERGVKKLGTNVANYITDLIENSLYQYDKISFIG
HSLGGVVQLYAIKYILMTKGPDYFERMRIKPVNFIGMASPFLGILNEMNF
LISWVLDMGTLGKTGRDLTLSKRLPAWSDISIGESKKRDSFKPVLETLPE
DPLQKFLTQFEQLVVYANAMNDGIVPLRTSALLYLDYEALGDVSELKKSK
HMHVHPELEEADHKIQVNRSRDTVSEVPEEANQMVQDIQDAAKSTDNSQS
TESSETMGKNHVISRYKEFLNLNFSEHNSNNHKPKLTKRQRKYKNFSVRG
TDYNVFNDVLPEDHSFQSEETNSTQDSQTIVVPPRASAIESAINTLICPI
PSNEFLINPESRQHVIFHDKYYQFNKSSQEEGNLNKHSKVEWFASVLLRY
HSKWKLEKQKQIADKYHNACGWRKVLVNLPLDAHNNIVVRRRFANGYGWG
VVDHLCDLFRVSENKL
Legend
This sequence has been compared to family alignement (MSA) red => minority aminoacid blue => majority aminoacid color intensity => conservation rate title => sequence position(MSA position)aminoacid rate Catalytic site Catalytic site in the MSA
M A A H P S L W Y R D K D S L R I G G V A R Y T I E Y T R L D P T I K R I Y F R L K N I E K S S I R A I H L L S G P F I L Y C H V V P C N Y N P R K P F H P E N V Q K N T E V V F E N Q I K P N Q A F N V S L L L N S N S L K G K D D K G Y D I F Q W E I E I V S Q I V I T K K T E V V Y D F M I G D D L H F M K K L G Q S I I Q Q T L T S L G T K I D M N E G T K P T I V D K A M D E I H N D S H K I Y N T Q L K V S K L T T D D I W S N E P K D P K K P V H L V I V T H G I F S N L T A D M L Y I K D Q L E L R V K E N I L V R G Y R Y N A G R T E R G V K K L G T N V A N Y I T D L I E N S L Y Q Y D K I S F I G H S L G G V V Q L Y A I K Y I L M T K G P D Y F E R M R I K P V N F I G M A S P F L G I L N E M N F L I S W V L D M G T L G K T G R D L T L S K R L P A W S D I S I G E S K K R D S F K P V L E T L P E D P L Q K F L T Q F E Q L V V Y A N A M N D G I V P L R T S A L L Y L D Y E A L G D V S E L K K S K H M H V H P E L E E A D H K I Q V N R S R D T V S E V P E E A N Q M V Q D I Q D A A K S T D N S Q S T E S S E T M G K N H V I S R Y K E F L N L N F S E H N S N N H K P K L T K R Q R K Y K N F S V R G T D Y N V F N D V L P E D H S F Q S E E T N S T Q D S Q T I V V P P R A S A I E S A I N T L I C P I P S N E F L I N P E S R Q H V I F H D K Y Y Q F N K S S Q E E G N L N K H S K V E W F A S V L L R Y H S K W K L E K Q K Q I A D K Y H N A C G W R K V L V N L P L D A H N N I V V R R R F A N G Y G W G V V D H L C D L F R V S E N K L
Reference
Title: The diploid genome sequence of Candida albicansJones T , Federspiel NA , Chibana H , Dungan J , Kalman S , Magee BB , Newport G , Thorstenson YR , Agabian N and Scherer S <2 more author(s)> Jones T , Federspiel NA , Chibana H , Dungan J , Kalman S , Magee BB , Newport G , Thorstenson YR , Agabian N , Magee PT , Davis RW , Scherer S (- 2) Ref: Proc Natl Acad Sci U S A, 101 :7329, 2004 : PubMed Abstract ESTHER: Jones_2004_Proc.Natl.Acad.Sci.U.S.A_101_7329 PubMedSearch: Jones 2004 Proc.Natl.Acad.Sci.U.S.A 101 7329 PubMedID: 15123810 Gene_locus related to this paper: canal-apth1 ,
canal-ATG15 ,
canal-bna7 ,
canal-c4yl13 ,
canal-cbpy ,
canal-LIP1 ,
canal-LIP2 ,
canal-LIP3 ,
canal-LIP4 ,
canal-LIP5 ,
canal-LIP6 ,
canal-LIP7 ,
canal-LIP8 ,
canal-LIP9 ,
canal-LIP10 ,
canal-ppme1 ,
canal-q5a0c9 ,
canal-q5a0i7 ,
canal-q5a2i9 ,
canal-q5a2u7 ,
canal-q5a6l4 ,
canal-q5a042 ,
canal-q5a948 ,
canal-q5aa97 ,
canal-q5abf2 ,
canal-q5acl5 ,
canal-q5ad17 ,
canal-q5adx4 ,
canal-q5ady2 ,
canal-q5aeu3 ,
canal-q5afp8 ,
canal-q5ag57 ,
canal-q5ah37 ,
canal-q5ai09 ,
canal-q5ai12 ,
canal-q5ai87 ,
canal-q5ajt3 ,
canal-q5ak09 ,
canal-q5ak29 ,
canal-q5ak96 ,
canal-q5akr2 ,
canal-q5akz5 ,
canal-q5amg8 ,
canal-q5amn4 ,
canal-q5amn7 ,
canal-q5ams2 ,
canal-q5ams7 ,
canal-q5apu4 ,
canal-q59k70 ,
canal-q59kl3 ,
canal-q59l46 ,
canal-q59ln6 ,
canal-q59m48 ,
canal-q59ng0 ,
canal-q59nl9 ,
canal-q59nw6 ,
canal-q59nx4 ,
canal-q59nx8 ,
canal-q59s22 ,
canal-q59tt5 ,
canal-q59u61 ,
canal-q59u64 ,
canal-q59vf1 ,
canal-q59vp0 ,
canal-q59we9 ,
canal-q59xq6 ,
canal-q59y42 ,
canal-q59y97 ,
canaw-c4yrr3 ,
canal-hda1 Abstract
We present the diploid genome sequence of the fungal pathogen Candida albicans. Because C. albicans has no known haploid or homozygous form, sequencing was performed as a whole-genome shotgun of the heterozygous diploid genome in strain SC5314, a clinical isolate that is the parent of strains widely used for molecular analysis. We developed computational methods to assemble a diploid genome sequence in good agreement with available physical mapping data. We provide a whole-genome description of heterozygosity in the organism. Comparative genomic analyses provide important clues about the evolution of the species and its mechanisms of pathogenesis.
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