Gene_Locus Report

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Gene_locus Report for: cryne-q5kc00

Cryptococcus neoformans (Filobasidiella neoformans) (and var. neoformans B-3501A) peptidase, putative

Relationship
Family|Prolyl_oligopeptidase_S9
Block| X
Position in NCBI Life Tree|Cryptococcus neoformans
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Fungi: N E > Dikarya: N E > Basidiomycota: N E > Agaricomycotina: N E > Tremellomycetes: N E > Tremellales: N E > Cryptococcaceae: N E > Cryptococcus [Filobasidiella]: N E > Cryptococcus neoformans species complex: N E > Cryptococcus neoformans: N E
Warning: This entry is a compilation of different species or line or strain with more than 90% amino acid identity. You can retrieve all strain data


Molecular evidence
Database
No mutation
No structure
No kinetic





No Substrate
No inhibitor
2 Genbank : AE017349, AAEY01000041
2 UniProt : Q5KC00, Q55NL2
2 UniProt : Q5KC00, Q55NL2
2 Interpro : Q5KC00, Q55NL2
2 Pfam : Q5KC00, Q55NL2
2 PIRSF : Q5KC00, Q55NL2
2 SUPERFAM : Q5KC00, Q55NL2
Sequence
Graphical view for this peptide sequence: cryne-q5kc00
Colored MSA for Prolyl_oligopeptidase_S9 (raw)
MRATVLTLLGLSASAWATPAPFTVEDMLAAPRPFPAIASPDKQHAIAVVD
YWEPRDDSMRREAYLATLNRPEVKHPISLFNTTPSAAADFFWLDDVTIAY
LDGSNLFSYPVEYAFSQSNFKPKHNPPRSPRHQKILSFPHGVNPTSLQYE
ASTKTLAFTGQVWSDGSFYQTRHHDKLYEKKRDSAQVYDDLMVRHWDTWR
VSGKVWTLGVVKLININDEWAELDNDINKHHKRRAEFINILNGTDLVSQT
DPIDAGSYSISSEHIAVAVKPPYLQTATHTREDIYLFPLPSSYDSASILP
KHVTPHAHGAISEIKFSPDGKKLSWLEMKKDGYESDRRVVVVYDLMSGKS
ERWTEVWDRSPKSISWAVDSQSIFLLAEFRGRTLPYHLTHPNHLPTPLLF
NGTTVSLTPLNETDILIARQSFRTPTVEWILTLPDPAEDGNAVGDGDGDK
IPAVEPLRQLTRWNEHFIRGRLDVQTGEEFWFKGAEGKDVMGWALKPRGW
KPDQKAKYPLAFLIHGGPQSAWDDSWSTRWNPALFAAQGYFVVAINPTGS
TGYGQEFTDAIQGDWGGKPFKDLLAGYHYVLENYPEIDPERTAGLGASYG
GYMVNWINGHNDHFGFKALVCHDGVFDTVTTFFSTEEIYFPTQDFAGTPW
TNRATYEKWNPVNHVIEWNTPELVIQGGKDYRLENSQGLGAFTALQLQGV
PSRFVYFPDENHWILKPHNSIKWHHEVFRWLEEWIGKPTDESEAFVVQRE
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MRATVLTLLGLSASAWATPAPFTVEDMLAAPRPFPAIASPDKQHAIAVVD
YWEPRDDSMRREAYLATLNRPEVKHPISLFNTTPSAAADFFWLDDVTIAY
LDGSNLFSYPVEYAFSQSNFKPKHNPPRSPRHQKILSFPHGVNPTSLQYE
ASTKTLAFTGQVWSDGSFYQTRHHDKLYEKKRDSAQVYDDLMVRHWDTWR
VSGKVWTLGVVKLININDEWAELDNDINKHHKRRAEFINILNGTDLVSQT
DPIDAGSYSISSEHIAVAVKPPYLQTATHTREDIYLFPLPSSYDSASILP
KHVTPHAHGAISEIKFSPDGKKLSWLEMKKDGYESDRRVVVVYDLMSGKS
ERWTEVWDRSPKSISWAVDSQSIFLLAEFRGRTLPYHLTHPNHLPTPLLF
NGTTVSLTPLNETDILIARQSFRTPTVEWILTLPDPAEDGNAVGDGDGDK
IPAVEPLRQLTRWNEHFIRGRLDVQTGEEFWFKGAEGKDVMGWALKPRGW
KPDQKAKYPLAFLIHGGPQSAWDDSWSTRWNPALFAAQGYFVVAINPTGS
TGYGQEFTDAIQGDWGGKPFKDLLAGYHYVLENYPEIDPERTAGLGASYG
GYMVNWINGHNDHFGFKALVCHDGVFDTVTTFFSTEEIYFPTQDFAGTPW
TNRATYEKWNPVNHVIEWNTPELVIQGGKDYRLENSQGLGAFTALQLQGV
PSRFVYFPDENHWILKPHNSIKWHHEVFRWLEEWIGKPTDESEAFVVQRE


Reference
    Title: The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans
    Loftus BJ, Fung E, Roncaglia P, Rowley D, Amedeo P, Bruno D, Vamathevan J, Miranda M, Anderson IJ and Hyman RW <44 more author(s)>
    Ref: Science, 307:1321, 2005 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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