Sus scrofa (Pig). Carboxylic ester hydrolase PLE-B9 pig liver esterase PLE6
PLE6 prefers to metabolize the esters that contain a small alcohol group and a large bulky acyl group || There are at least 6 isoenzyme (may be different genes Q9TS80 PLE1 A5A4F5 PLE3). Isoenzymes of pig-liver esterase reveal striking differences in enantioselectivities Hummel et al. 2007<\/A>. Polyisoprenylated. methylated protein methyl esterase (PMPMEase). Pig liver esterase 5 (PLE5) (pig-a9gyw6<\/A>) is the isoenzyme crystallized (5FV4<\/A>)
MWLLPLVLTS LASSATWAGQ PASPPVVDTA QGRVLGKYVS LEGLAQPVAV FLGVPFAKPP LGSLRFAPPQ PAEPWSFVKN TTSYPPMCCQ DQLGEQMLSD LFTNRKERLI PEFSEDCLYL NIYTPADLTK RGRLPVMVWI HGGGLVVGGA STYDGLALAA HENVVVVAIQ YRLGIWGFFS TGDEHSRGNW GHLDQVAALH WVQENIANFG GDPGSVTIFG ESAGGESVSV LVLSPLAKNL FHRAISESGV AFTAGLVRKD MKAAAKQIAV LAGCKTTTSA VFVHCLRQKS EDELLDLTLK MKFFALDLHG DPRESHPFLT TVVDGVLLPK MPEEILAEKD FNTVPYIVGI NKQEFGWLLP TMMGFPLSEG KLDQKTATSL LWKSYPIANI PEELTPVATD KYLGGTDDPV KKKDLFLDLM GDVVFGVPSV TVARQHRDAG APTYMYEFQY RPSFSSDKKP KTVIGDHGDE IFSVFGAPFL RGDAPEEEVS LSKMVMKFWA NFARSGNPNG EGLPHWPMYD QEEGYLQIGV NTQAAKRLKG EEVAFWNDLL SKEAAKKPPK IKHAEL
| Title : Pig Liver Esterases Hydrolyze Endocannabinoids and Promote Inflammatory Response - Zhou_2021_Front.Immunol_12_670427 |
| Author(s) : Zhou Q , Yan B , Sun W , Chen Q , Xiao Q , Xiao Y , Wang X , Shi D |
| Ref : Front Immunol , 12 :670427 , 2021 |
| Abstract : Zhou_2021_Front.Immunol_12_670427 |
| ESTHER : Zhou_2021_Front.Immunol_12_670427 |
| PubMedSearch : Zhou_2021_Front.Immunol_12_670427 |
| PubMedID: 34079552 |
| Gene_locus related to this paper: pig-PLE1 , pig-a0a1s6l967 |
| Title : Pig liver esterases PLE1 and PLE6: heterologous expression, hydrolysis of common antibiotics and pharmacological consequences - Zhou_2019_Sci.Rep_9_15564 |
| Author(s) : Zhou Q , Xiao Q , Zhang Y , Wang X , Xiao Y , Shi D |
| Ref : Sci Rep , 9 :15564 , 2019 |
| Abstract : Zhou_2019_Sci.Rep_9_15564 |
| ESTHER : Zhou_2019_Sci.Rep_9_15564 |
| PubMedSearch : Zhou_2019_Sci.Rep_9_15564 |
| PubMedID: 31664043 |
| Gene_locus related to this paper: pig-EST1 , pig-a0a1s6l967 |
| Title : Regioselective ester cleavage of di-(2-ethylhexyl) trimellitates by porcine liver esterase - Hollerer_2018_Toxicol.In.Vitro_47_178 |
| Author(s) : Hollerer C , Becker G , Goen T , Eckert E |
| Ref : Toxicol In Vitro , 47 :178 , 2018 |
| Abstract : Hollerer_2018_Toxicol.In.Vitro_47_178 |
| ESTHER : Hollerer_2018_Toxicol.In.Vitro_47_178 |
| PubMedSearch : Hollerer_2018_Toxicol.In.Vitro_47_178 |
| PubMedID: 29180039 |
| Gene_locus related to this paper: pig-a9gyw6 , pig-EST1 , pig-a0a1s6l948 , pig-a0a1s6l967 |
| Title : Breed Differences in Pig Liver Esterase (PLE) between Tongcheng (Chinese Local Breed) and Large White Pigs - Xiao_2018_Sci.Rep_8_16364 |
| Author(s) : Xiao Q , Zhou Q , Yang L , Tian Z , Wang X , Xiao Y , Shi D |
| Ref : Sci Rep , 8 :16364 , 2018 |
| Abstract : Xiao_2018_Sci.Rep_8_16364 |
| ESTHER : Xiao_2018_Sci.Rep_8_16364 |
| PubMedSearch : Xiao_2018_Sci.Rep_8_16364 |
| PubMedID: 30397234 |
| Gene_locus related to this paper: pig-a9gyw6 , pig-EST1 , pig-PLE1 , pig-a0a1s6l948 , pig-a0a1s6l959 , pig-a0a1s6l967 |
| Title : Third-Generation Sequencing and Analysis of Four Complete Pig Liver Esterase Gene Sequences in Clones Identified by Screening BAC Library - Zhou_2016_PLoS.One_11_e0163295 |
| Author(s) : Zhou Q , Sun W , Liu X , Wang X , Xiao Y , Bi D , Yin J , Shi D |
| Ref : PLoS ONE , 11 :e0163295 , 2016 |
| Abstract : Zhou_2016_PLoS.One_11_e0163295 |
| ESTHER : Zhou_2016_PLoS.One_11_e0163295 |
| PubMedSearch : Zhou_2016_PLoS.One_11_e0163295 |
| PubMedID: 27695062 |
| Gene_locus related to this paper: pig-EST1 , pig-PLE1 , pig-a0a1s6l948 , pig-a0a1s6l959 , pig-a0a1s6l967 |